DK170801B1 - Terapeutisk aktivt, substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende benzimidazolderivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mavetarmkanallidelser hos pattedyr sam - Google Patents
Terapeutisk aktivt, substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende benzimidazolderivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mavetarmkanallidelser hos pattedyr sam Download PDFInfo
- Publication number
- DK170801B1 DK170801B1 DK122391A DK122391A DK170801B1 DK 170801 B1 DK170801 B1 DK 170801B1 DK 122391 A DK122391 A DK 122391A DK 122391 A DK122391 A DK 122391A DK 170801 B1 DK170801 B1 DK 170801B1
- Authority
- DK
- Denmark
- Prior art keywords
- derivative
- compound
- mammals
- preparing
- benzimidazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8804628 | 1988-12-22 | ||
SE19888804628A SE8804628D0 (sv) | 1988-12-22 | 1988-12-22 | New compounds |
SE8900741 | 1989-03-13 | ||
PCT/SE1989/000741 WO1990006926A1 (en) | 1988-12-22 | 1989-12-20 | Therapeutically active substituted benzimidazole and process for its preparation |
Publications (3)
Publication Number | Publication Date |
---|---|
DK122391D0 DK122391D0 (da) | 1991-06-21 |
DK122391A DK122391A (da) | 1991-06-24 |
DK170801B1 true DK170801B1 (da) | 1996-01-22 |
Family
ID=20374309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK122391A DK170801B1 (da) | 1988-12-22 | 1991-06-21 | Terapeutisk aktivt, substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende benzimidazolderivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mavetarmkanallidelser hos pattedyr sam |
Country Status (26)
Country | Link |
---|---|
US (1) | US5019584A (zh) |
EP (1) | EP0451188B1 (zh) |
JP (1) | JP2793907B2 (zh) |
CN (1) | CN1028232C (zh) |
AT (1) | ATE110379T1 (zh) |
AU (1) | AU636866B2 (zh) |
CA (1) | CA2005987C (zh) |
DD (1) | DD296077A5 (zh) |
DE (1) | DE68917738T2 (zh) |
DK (1) | DK170801B1 (zh) |
FI (1) | FI913036A0 (zh) |
GR (1) | GR1000318B (zh) |
HU (1) | HUT57203A (zh) |
IE (1) | IE64850B1 (zh) |
IL (1) | IL92797A (zh) |
LT (1) | LT3981B (zh) |
LV (1) | LV10268B (zh) |
NO (1) | NO178338C (zh) |
PH (1) | PH27257A (zh) |
PT (1) | PT92647B (zh) |
RO (1) | RO110496B1 (zh) |
RU (1) | RU2070199C1 (zh) |
SE (1) | SE8804628D0 (zh) |
WO (1) | WO1990006926A1 (zh) |
YU (1) | YU242589A (zh) |
ZA (1) | ZA899796B (zh) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL166209B1 (pl) * | 1990-06-20 | 1995-04-28 | Astra Ab | Sposób wytwarzania nowych pochodnych benzimidazolu PL |
WO1993006097A1 (en) * | 1991-09-20 | 1993-04-01 | Merck & Co., Inc. | Novel process for the preparation of anti-ulcer agents |
US6016044A (en) * | 1995-09-11 | 2000-01-18 | Alaris Medical Systems, Inc. | Open-loop step motor control system |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6645988B2 (en) * | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
CA2472103A1 (en) * | 2002-01-25 | 2003-08-07 | Santarus, Inc. | Transmucosal delivery of proton pump inhibitors |
US20050234103A1 (en) * | 2002-03-26 | 2005-10-20 | Reddy Manne S | Crystalline forms of rabeprazole sodium |
EP1603537A4 (en) * | 2003-02-20 | 2009-11-04 | Santarus Inc | IMMEDIATE RELEASE OF OMEPRAZOLE ANTACIDAL COMPLEX WITH NEW FORMULATION FOR RAPID AND PROLONGED ELIMINATION OF GASTRIC ACID |
JP2006528181A (ja) * | 2003-07-18 | 2006-12-14 | サンタラス インコーポレイティッド | 酸分泌を阻害するために有用な薬学的製剤ならびにそれらを作製および使用する方法 |
AU2004257864A1 (en) * | 2003-07-18 | 2005-01-27 | Santarus, Inc. | Pharmaceutical formulation and method for treating acid-caused gastrointestinal disorders |
US8993599B2 (en) * | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US20070292498A1 (en) * | 2003-11-05 | 2007-12-20 | Warren Hall | Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers |
US8815916B2 (en) * | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) * | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US20090092658A1 (en) * | 2007-10-05 | 2009-04-09 | Santarus, Inc. | Novel formulations of proton pump inhibitors and methods of using these formulations |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE418966B (sv) | 1974-02-18 | 1981-07-06 | Haessle Ab | Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan |
SE416649B (sv) | 1974-05-16 | 1981-01-26 | Haessle Ab | Forfarande for framstellning av foreningar som paverkar magsyrasekretionen |
IN148930B (zh) | 1977-09-19 | 1981-07-25 | Hoffmann La Roche | |
SE7804231L (sv) | 1978-04-14 | 1979-10-15 | Haessle Ab | Magsyrasekretionsmedel |
US4359465A (en) | 1980-07-28 | 1982-11-16 | The Upjohn Company | Methods for treating gastrointestinal inflammation |
CH644116A5 (de) | 1980-08-21 | 1984-07-13 | Hoffmann La Roche | Imidazolderivate. |
US4331671A (en) * | 1981-01-09 | 1982-05-25 | Sterling Drug Inc. | 5-(Pyridinyl)-1H-benzimidazoles and 1-hydroxy-6-(pyridinyl)-1H-benzimidazoles and their cardiotonic use |
HU195220B (en) | 1983-05-03 | 1988-04-28 | Byk Gulden Lomberg Chem Fqb | Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them |
JPS6150978A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
JPS6150979A (ja) | 1984-08-16 | 1986-03-13 | Takeda Chem Ind Ltd | ピリジン誘導体およびその製造法 |
SE8500996D0 (sv) * | 1985-03-01 | 1985-03-01 | Haessle Ab | Method of treatment |
US4738975A (en) * | 1985-07-02 | 1988-04-19 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, and use as anti-ulcer agents |
GB8610607D0 (en) * | 1986-04-30 | 1986-06-04 | Smith Kline French Lab | Chemical compounds |
FR2593178B1 (fr) * | 1986-01-20 | 1988-04-29 | Esteve Labor Dr | Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments. |
WO1989003830A1 (en) * | 1987-10-30 | 1989-05-05 | Aktiebolaget Hässle | 2-pyridinylmethyl (sulfinyl or thio)benzimidazoles for treatment of diseases related to bone loss |
-
1988
- 1988-12-22 SE SE19888804628A patent/SE8804628D0/xx unknown
-
1989
- 1989-12-18 IE IE404989A patent/IE64850B1/xx not_active IP Right Cessation
- 1989-12-19 GR GR890100834A patent/GR1000318B/el unknown
- 1989-12-19 CA CA002005987A patent/CA2005987C/en not_active Expired - Lifetime
- 1989-12-19 IL IL9279789A patent/IL92797A/en not_active IP Right Cessation
- 1989-12-19 PH PH39730A patent/PH27257A/en unknown
- 1989-12-20 RO RO147868A patent/RO110496B1/ro unknown
- 1989-12-20 EP EP90901080A patent/EP0451188B1/en not_active Expired - Lifetime
- 1989-12-20 AU AU48176/90A patent/AU636866B2/en not_active Ceased
- 1989-12-20 JP JP2501538A patent/JP2793907B2/ja not_active Expired - Fee Related
- 1989-12-20 WO PCT/SE1989/000741 patent/WO1990006926A1/en active IP Right Grant
- 1989-12-20 ZA ZA899796A patent/ZA899796B/xx unknown
- 1989-12-20 HU HU901085A patent/HUT57203A/hu unknown
- 1989-12-20 US US07/454,046 patent/US5019584A/en not_active Expired - Lifetime
- 1989-12-20 AT AT90901080T patent/ATE110379T1/de not_active IP Right Cessation
- 1989-12-20 RU SU894895822A patent/RU2070199C1/ru active
- 1989-12-20 DE DE68917738T patent/DE68917738T2/de not_active Expired - Fee Related
- 1989-12-20 DD DD89335979A patent/DD296077A5/de not_active IP Right Cessation
- 1989-12-21 CN CN89109588A patent/CN1028232C/zh not_active Expired - Fee Related
- 1989-12-21 PT PT92647A patent/PT92647B/pt not_active IP Right Cessation
- 1989-12-21 YU YU02425/89A patent/YU242589A/xx unknown
-
1991
- 1991-06-20 NO NO912416A patent/NO178338C/no unknown
- 1991-06-20 FI FI913036A patent/FI913036A0/fi not_active Application Discontinuation
- 1991-06-21 DK DK122391A patent/DK170801B1/da not_active IP Right Cessation
-
1993
- 1993-06-28 LV LVP-93-692A patent/LV10268B/lv unknown
- 1993-12-30 LT LTIP1722A patent/LT3981B/lt not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK170801B1 (da) | Terapeutisk aktivt, substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende benzimidazolderivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mavetarmkanallidelser hos pattedyr sam | |
US5008278A (en) | Therapeutically active compound and a process for its preparation | |
US4965269A (en) | Therapeutically active chloro substituted benzimidazoles | |
NZ207348A (en) | Omeprazole-(5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl)-sulfinyl)-1h-benzimidazole) | |
CA2005980C (en) | Benzimidazole derivative with gastric acid inhibitory effect and process for its preparation | |
NO178337B (no) | Analogifremgangsmåte for fremstilling av terapeutisk aktiv 5-fluor-2[[(4-cyklopropyl-(metoksy-2-pyridinyl)metylÅsulfinylÅ-1H-benzimidazol og mellomprodukter |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |