DK170773B1 - Fremgangsmåde til fremstilling af d-alfa-tocopherol - Google Patents
Fremgangsmåde til fremstilling af d-alfa-tocopherol Download PDFInfo
- Publication number
- DK170773B1 DK170773B1 DK248584A DK248584A DK170773B1 DK 170773 B1 DK170773 B1 DK 170773B1 DK 248584 A DK248584 A DK 248584A DK 248584 A DK248584 A DK 248584A DK 170773 B1 DK170773 B1 DK 170773B1
- Authority
- DK
- Denmark
- Prior art keywords
- general formula
- compound
- tocopherol
- protecting group
- ether
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
- C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Epoxy Compounds (AREA)
- Glass Compositions (AREA)
- Optical Integrated Circuits (AREA)
- Optical Couplings Of Light Guides (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH339183 | 1983-06-21 | ||
CH339183 | 1983-06-21 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK248584D0 DK248584D0 (da) | 1984-05-17 |
DK248584A DK248584A (da) | 1984-12-22 |
DK170773B1 true DK170773B1 (da) | 1996-01-15 |
Family
ID=4254962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK248584A DK170773B1 (da) | 1983-06-21 | 1984-05-17 | Fremgangsmåde til fremstilling af d-alfa-tocopherol |
Country Status (6)
Country | Link |
---|---|
US (2) | US4582919A (ja) |
EP (1) | EP0129252B1 (ja) |
JP (1) | JPS6013781A (ja) |
AT (1) | ATE55382T1 (ja) |
DE (1) | DE3482917D1 (ja) |
DK (1) | DK170773B1 (ja) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK354085A (da) * | 1984-08-28 | 1986-03-01 | Hoffmann La Roche | Fremgangsmaade til fremstilling af optisk aktive forbindelser |
DK401287A (da) * | 1986-08-25 | 1988-02-26 | Hoffmann La Roche | Fremgangsmaade til fremstilling af opstisk aktive forbindelser |
US5034546A (en) * | 1986-11-28 | 1991-07-23 | Hoffmann-La Roche Inc. | Novel vitamin E intermediates and a process for their manufacture and conversion into vitamin E |
DK559887A (da) * | 1986-11-28 | 1988-05-29 | Hoffmann La Roche | Fremgangsmaade til fremstilling af carbinolderivater |
JP2912399B2 (ja) * | 1988-08-02 | 1999-06-28 | エフ・ホフマン‐ラ ロシユ アーゲー | トコフエロールの製造方法 |
US5348869A (en) * | 1988-08-02 | 1994-09-20 | Hoffmann-La Roche Inc. | Process for producing tocopherols with spheroplasts of algae |
DE4120166C2 (de) * | 1991-06-19 | 1994-10-06 | Friedrichs Konrad Kg | Strangpreßwerkzeug zur Herstellung eines Hartmetall- oder Keramikstabes mit gedrallten Innenbohrungen |
EP0531639B1 (en) * | 1991-07-18 | 1999-09-01 | F. Hoffmann-La Roche Ag | Tocopherol cyclase |
WO2000010994A1 (en) * | 1998-08-19 | 2000-03-02 | Sankyo Company, Limited | Process for the preparation of 2-(aryloxymethyl)-2,5,7,8-tetramethylchroman-6-ols |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3992420A (en) * | 1972-06-12 | 1976-11-16 | Ciba-Geigy Corporation | 3,5-dialkyl-4-hydroxybenzyl-oxiranes |
JPS57136582A (en) * | 1981-02-19 | 1982-08-23 | Eisai Co Ltd | Preparation of optically active alpha-tocopherol |
JPS57183782A (en) * | 1981-04-30 | 1982-11-12 | Sumitomo Chem Co Ltd | Preparation of coumarone compound |
DK449983A (da) * | 1982-10-27 | 1984-04-28 | Hoffmann La Roche | Fremgangsmaade til fremstilling af optiske aktive forbindelser |
-
1984
- 1984-05-17 DK DK248584A patent/DK170773B1/da not_active IP Right Cessation
- 1984-06-11 US US06/619,654 patent/US4582919A/en not_active Expired - Lifetime
- 1984-06-19 JP JP59124606A patent/JPS6013781A/ja active Granted
- 1984-06-20 EP EP84107062A patent/EP0129252B1/de not_active Expired - Lifetime
- 1984-06-20 AT AT84107062T patent/ATE55382T1/de not_active IP Right Cessation
- 1984-06-20 DE DE8484107062T patent/DE3482917D1/de not_active Expired - Lifetime
-
1986
- 1986-01-13 US US06/818,451 patent/US4709055A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK248584D0 (da) | 1984-05-17 |
DK248584A (da) | 1984-12-22 |
ATE55382T1 (de) | 1990-08-15 |
US4709055A (en) | 1987-11-24 |
US4582919A (en) | 1986-04-15 |
EP0129252A3 (en) | 1988-01-13 |
EP0129252A2 (de) | 1984-12-27 |
EP0129252B1 (de) | 1990-08-08 |
DE3482917D1 (de) | 1990-09-13 |
JPH0572387B2 (ja) | 1993-10-12 |
JPS6013781A (ja) | 1985-01-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |