DK1696909T3 - Benzothiazolderivater til behandling af diabetes - Google Patents
Benzothiazolderivater til behandling af diabetesInfo
- Publication number
- DK1696909T3 DK1696909T3 DK04787110T DK04787110T DK1696909T3 DK 1696909 T3 DK1696909 T3 DK 1696909T3 DK 04787110 T DK04787110 T DK 04787110T DK 04787110 T DK04787110 T DK 04787110T DK 1696909 T3 DK1696909 T3 DK 1696909T3
- Authority
- DK
- Denmark
- Prior art keywords
- unsubstituted
- substituted
- treatment
- benzothiazole derivatives
- group
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03102740 | 2003-09-12 | ||
| PCT/EP2004/052090 WO2005025567A1 (en) | 2003-09-12 | 2004-09-08 | Benzothiazole derivatives for the treatment of diabetes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1696909T3 true DK1696909T3 (da) | 2008-01-02 |
Family
ID=34306921
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04787110T DK1696909T3 (da) | 2003-09-12 | 2004-09-08 | Benzothiazolderivater til behandling af diabetes |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20070088017A1 (pl) |
| EP (1) | EP1696909B1 (pl) |
| JP (1) | JP5021307B2 (pl) |
| AT (1) | ATE378047T1 (pl) |
| AU (1) | AU2004271740B2 (pl) |
| CA (1) | CA2534314C (pl) |
| CY (1) | CY1107820T1 (pl) |
| DE (1) | DE602004010178T2 (pl) |
| DK (1) | DK1696909T3 (pl) |
| ES (1) | ES2297494T3 (pl) |
| HK (1) | HK1096594A1 (pl) |
| HR (1) | HRP20070527T3 (pl) |
| IL (1) | IL174250A (pl) |
| NO (1) | NO20061600L (pl) |
| PL (1) | PL1696909T3 (pl) |
| PT (1) | PT1696909E (pl) |
| SI (1) | SI1696909T1 (pl) |
| WO (1) | WO2005025567A1 (pl) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7838522B2 (en) * | 2004-11-17 | 2010-11-23 | Ares Trading S.A. | Benzothiazole formulations and use thereof |
| KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 ｊｎｋ 억제제 |
| BRPI0613042A2 (pt) | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
| US7678363B2 (en) | 2005-08-26 | 2010-03-16 | Braincells Inc | Methods of treating psychiatric conditions comprising administration of muscarinic agents in combination with SSRIs |
| EP2258359A3 (en) | 2005-08-26 | 2011-04-06 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation with sabcomelin |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| US20070112017A1 (en) | 2005-10-31 | 2007-05-17 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| EP2021000A2 (en) | 2006-05-09 | 2009-02-11 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| PT2054049E (pt) | 2006-08-24 | 2016-06-02 | Univ Tennessee Res Found | Acilanilidas substituídas e métodos de utilização das mesmas |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2008125518A2 (en) * | 2007-04-17 | 2008-10-23 | Merck Serono S.A. | Process for the preparation of piperazine benzothiazoles |
| UA100527C2 (en) * | 2007-10-10 | 2013-01-10 | Астразенека Аб | Benzothiazoles as ghrelin receptor modulators |
| US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| US9622992B2 (en) | 2012-07-13 | 2017-04-18 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
| US10314807B2 (en) | 2012-07-13 | 2019-06-11 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
| CN108143728A (zh) | 2012-07-13 | 2018-06-12 | Gtx公司 | 选择性雄激素受体调节剂在治疗乳癌中的用途 |
| US9744149B2 (en) | 2012-07-13 | 2017-08-29 | Gtx, Inc. | Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs) |
| US9969683B2 (en) | 2012-07-13 | 2018-05-15 | Gtx, Inc. | Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS) |
| US10258596B2 (en) | 2012-07-13 | 2019-04-16 | Gtx, Inc. | Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS) |
| US10987334B2 (en) | 2012-07-13 | 2021-04-27 | University Of Tennessee Research Foundation | Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs) |
| CN104903331A (zh) * | 2013-01-24 | 2015-09-09 | 山东亨利医药科技有限责任公司 | Jnk抑制剂 |
| WO2017025980A2 (en) * | 2015-08-12 | 2017-02-16 | Shoolineuniversity Of Biotechnology And Management Sciences | Novel benzothiazole derivatives with enhanced biological activity |
| US11970467B1 (en) | 2023-10-13 | 2024-04-30 | King Faisal University | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as an antimicrobial compound |
| US11905260B1 (en) | 2023-10-13 | 2024-02-20 | King Faisal University | N′-(1-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as an antimicrobial compound |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1176269A (en) * | 1981-03-02 | 1984-10-16 | Kazimir Sestanj | N-naphthoylglycine derivatives |
| US4927831A (en) * | 1988-10-20 | 1990-05-22 | American Home Products | Spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors |
| US6559188B1 (en) * | 1999-09-17 | 2003-05-06 | Novartis Ag | Method of treating metabolic disorders especially diabetes, or a disease or condition associated with diabetes |
| EP1110957A1 (en) * | 1999-12-24 | 2001-06-27 | Applied Research Systems ARS Holding N.V. | Benzazole derivatives and their use as JNK modulators |
| WO2003047570A1 (en) * | 2001-12-07 | 2003-06-12 | Applied Research Systems Ars Holding N.V. | Benzazole derivatives for the treatment of scleroderma |
| IL164796A (en) * | 2002-04-25 | 2013-02-28 | Pascale Gailllard | Piperazine benzothiazole derivatives, their preparation, pharmaceutical compositions containing them and their use |
-
2004
- 2004-09-08 PT PT04787110T patent/PT1696909E/pt unknown
- 2004-09-08 AT AT04787110T patent/ATE378047T1/de active
- 2004-09-08 EP EP04787110A patent/EP1696909B1/en active Active
- 2004-09-08 DK DK04787110T patent/DK1696909T3/da active
- 2004-09-08 ES ES04787110T patent/ES2297494T3/es active Active
- 2004-09-08 SI SI200430550T patent/SI1696909T1/sl unknown
- 2004-09-08 AU AU2004271740A patent/AU2004271740B2/en not_active Ceased
- 2004-09-08 WO PCT/EP2004/052090 patent/WO2005025567A1/en active IP Right Grant
- 2004-09-08 US US10/571,291 patent/US20070088017A1/en not_active Abandoned
- 2004-09-08 DE DE602004010178T patent/DE602004010178T2/de active Active
- 2004-09-08 CA CA2534314A patent/CA2534314C/en not_active Expired - Fee Related
- 2004-09-08 PL PL04787110T patent/PL1696909T3/pl unknown
- 2004-09-08 JP JP2006525827A patent/JP5021307B2/ja not_active Expired - Fee Related
-
2006
- 2006-03-12 IL IL174250A patent/IL174250A/en not_active IP Right Cessation
- 2006-04-07 NO NO20061600A patent/NO20061600L/no not_active Application Discontinuation
-
2007
- 2007-02-28 HK HK07102247A patent/HK1096594A1/xx not_active IP Right Cessation
- 2007-11-16 HR HR20070527T patent/HRP20070527T3/xx unknown
- 2007-12-04 CY CY20071101543T patent/CY1107820T1/el unknown
-
2013
- 2013-10-08 US US14/048,690 patent/US20140107116A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1696909A1 (en) | 2006-09-06 |
| HK1096594A1 (en) | 2007-06-08 |
| AU2004271740B2 (en) | 2010-10-28 |
| WO2005025567A1 (en) | 2005-03-24 |
| AU2004271740A1 (en) | 2005-03-24 |
| US20070088017A1 (en) | 2007-04-19 |
| CA2534314C (en) | 2012-11-13 |
| NO20061600L (no) | 2006-04-07 |
| ATE378047T1 (de) | 2007-11-15 |
| US20140107116A1 (en) | 2014-04-17 |
| ES2297494T3 (es) | 2008-05-01 |
| JP2007505083A (ja) | 2007-03-08 |
| EP1696909B1 (en) | 2007-11-14 |
| CY1107820T1 (el) | 2013-06-19 |
| CA2534314A1 (en) | 2005-03-24 |
| JP5021307B2 (ja) | 2012-09-05 |
| SI1696909T1 (sl) | 2008-02-29 |
| DE602004010178T2 (de) | 2008-09-11 |
| HRP20070527T3 (en) | 2007-12-31 |
| IL174250A0 (en) | 2006-08-01 |
| PL1696909T3 (pl) | 2008-04-30 |
| DE602004010178D1 (de) | 2007-12-27 |
| PT1696909E (pt) | 2007-12-21 |
| IL174250A (en) | 2011-01-31 |
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