DK1695088T3 - Fremgangsmåde til at analysere metabolitter - Google Patents
Fremgangsmåde til at analysere metabolitterInfo
- Publication number
- DK1695088T3 DK1695088T3 DK04804051.3T DK04804051T DK1695088T3 DK 1695088 T3 DK1695088 T3 DK 1695088T3 DK 04804051 T DK04804051 T DK 04804051T DK 1695088 T3 DK1695088 T3 DK 1695088T3
- Authority
- DK
- Denmark
- Prior art keywords
- metabolites
- biological sample
- isotopically labeled
- sample
- determining
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y10T436/144444—Glucose
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25625—Dilution
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03029370 | 2003-12-19 | ||
PCT/EP2004/014450 WO2005059556A1 (en) | 2003-12-19 | 2004-12-17 | Method for analysing metabolites |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1695088T3 true DK1695088T3 (da) | 2012-06-25 |
Family
ID=34684550
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04804051.3T DK1695088T3 (da) | 2003-12-19 | 2004-12-17 | Fremgangsmåde til at analysere metabolitter |
Country Status (8)
Country | Link |
---|---|
US (1) | US8420406B2 (da) |
EP (1) | EP1695088B1 (da) |
AT (1) | ATE554391T1 (da) |
AU (1) | AU2004299949B2 (da) |
CA (1) | CA2547755C (da) |
DK (1) | DK1695088T3 (da) |
ES (1) | ES2385330T3 (da) |
WO (1) | WO2005059556A1 (da) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005059556A1 (en) | 2003-12-19 | 2005-06-30 | Max Planck Geselllschaft Zur Förderung Der Wissenschaften E.V. | Method for analysing metabolites |
US20060200316A1 (en) * | 2005-03-01 | 2006-09-07 | Harin Kanani | Data correction, normalization and validation for quantitative high-throughput metabolomic profiling |
US20090203145A1 (en) * | 2008-02-07 | 2009-08-13 | Min Huang | Methods for analysis of vitamins |
EP2891882B1 (en) * | 2008-12-05 | 2018-08-15 | C2N Diagnostics | Methods for measuring concentrations of biomolecules |
WO2011123479A1 (en) * | 2010-03-29 | 2011-10-06 | Academia Sinica | Quantitative measurement of nano / micro particle endocytosis with cell mass spectrometry |
US20130037709A1 (en) * | 2010-05-01 | 2013-02-14 | Edward J. Barbieri | Method for Clinically Monitoring Niacin and Niacin Metabolites in Serum or Plasma |
EP2812686A4 (en) * | 2012-02-10 | 2016-04-13 | Childrens Medical Center | NMR BASED METABOLITE SCREENING PLATFORM |
US10607723B2 (en) | 2016-07-05 | 2020-03-31 | University Of Kentucky Research Foundation | Method and system for identification of metabolites using mass spectra |
EP3586137A4 (en) * | 2017-02-24 | 2020-11-04 | Iroa Technologies, LLC | IROA METABOLOMIC WORKFLOW FOR IMPROVED ACCURACY, IDENTIFICATION AND QUANTIFICATION |
CN107589194B (zh) * | 2017-11-02 | 2019-01-29 | 武汉迈特维尔生物科技有限公司 | 一种肺癌早期诊断用小分子标志物及在诊断方面的应用 |
EP3934423A1 (en) * | 2019-03-08 | 2022-01-12 | Basf Se | Metabolic analysis method |
CN112697894A (zh) * | 2020-11-30 | 2021-04-23 | 重庆医科大学附属口腔医院 | 氨基酸同位素标记物的定量分析方法 |
CN113514531B (zh) * | 2021-04-27 | 2022-10-25 | 清华大学 | 一种化合物的碎片离子预测方法及应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9117634D0 (en) * | 1991-08-15 | 1991-10-02 | Evans Lloyd T | Method of treating plants or plant tissues |
US6391649B1 (en) * | 1999-05-04 | 2002-05-21 | The Rockefeller University | Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy |
US20030077572A1 (en) * | 2001-10-11 | 2003-04-24 | Abramson Fred P. | Quantitative differential display using isotope ratio monitoring |
US20030180710A1 (en) * | 2002-03-22 | 2003-09-25 | Lee Wai-Nang Paul | Method of enhancing the efficiency of a pharmaceutical business |
SG152923A1 (en) * | 2002-09-16 | 2009-06-29 | Univ California | Biochemical methods for measuring metabolic fitness of tissues or whole organisms |
US20050112706A1 (en) * | 2002-11-07 | 2005-05-26 | Susan Kasper | Diagnostic and prognostic methods for prostate cancers |
US6872516B2 (en) * | 2003-04-16 | 2005-03-29 | Advanced Breath Diagnostics, Llc | Methods of producing carbon-13 labeled biomass |
EP1686372A4 (en) * | 2003-11-21 | 2009-04-01 | Eisai R&D Man Co Ltd | QUANTIFICATION METHOD USING AN ISOTOPE-MARKED INTERNAL CALIBRATION, ANALYSIS SYSTEM FOR EXECUTING THE QUANTIFICATION METHOD AND ASSOCIATED SEPARATION PROGRAM |
WO2005059556A1 (en) | 2003-12-19 | 2005-06-30 | Max Planck Geselllschaft Zur Förderung Der Wissenschaften E.V. | Method for analysing metabolites |
-
2004
- 2004-12-17 WO PCT/EP2004/014450 patent/WO2005059556A1/en active Application Filing
- 2004-12-17 US US10/580,024 patent/US8420406B2/en not_active Expired - Fee Related
- 2004-12-17 AT AT04804051T patent/ATE554391T1/de active
- 2004-12-17 CA CA2547755A patent/CA2547755C/en not_active Expired - Fee Related
- 2004-12-17 ES ES04804051T patent/ES2385330T3/es active Active
- 2004-12-17 AU AU2004299949A patent/AU2004299949B2/en not_active Ceased
- 2004-12-17 EP EP04804051A patent/EP1695088B1/en not_active Not-in-force
- 2004-12-17 DK DK04804051.3T patent/DK1695088T3/da active
Also Published As
Publication number | Publication date |
---|---|
AU2004299949B2 (en) | 2011-11-24 |
WO2005059556A1 (en) | 2005-06-30 |
AU2004299949A1 (en) | 2005-06-30 |
EP1695088A1 (en) | 2006-08-30 |
CA2547755A1 (en) | 2005-06-30 |
US8420406B2 (en) | 2013-04-16 |
ES2385330T3 (es) | 2012-07-23 |
ATE554391T1 (de) | 2012-05-15 |
US20070141712A1 (en) | 2007-06-21 |
CA2547755C (en) | 2014-06-03 |
EP1695088B1 (en) | 2012-04-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK1695088T3 (da) | Fremgangsmåde til at analysere metabolitter | |
Kool et al. | Advances in mass spectrometry-based post-column bioaffinity profiling of mixtures | |
ATE418729T1 (de) | Verfahren zur charakterisierung von biomolekülen mittels resultat-gesteuerter strategie | |
MY145833A (en) | Micro-hydrocarbon analysis | |
US20210080469A1 (en) | Anoliter-scale sample processing and mass spectrometry acquisition method for single cell proteomics | |
ATE350666T1 (de) | Verfahren zur analyse von proteinproben | |
ATE378420T1 (de) | Mediator-stabilisierende verbindung und methoden zur verwendung zur detektion elektrochemischer analyte | |
WO2007140291A3 (en) | Expression quantification using mass spectrometry | |
WO2007139956A3 (en) | Methods and systems for the quantitative analysis of biomarkers | |
WO2008022205A3 (en) | Thyroxine-containing compound analysis methods | |
US9068995B2 (en) | Method for determining derivatized analytes in a separated biological fluid | |
ATE548651T1 (de) | Verfahren zur klassifizierung chemisch quervernetzter zellulärer proben unter verwendung von massenspektren | |
WO2007090081A3 (en) | Analysis of mycophenolic acid in saliva using liquid chromatography tandem mass spectrometry | |
BRPI0606239A2 (pt) | métodos de análise de um ou mais compostos pesticidas | |
Pascual‐Caro et al. | Comparison of different chiral selectors for the enantiomeric determination of amphetamine‐type substances in human urine by solid‐phase extraction followed by capillary electrophoresis‐tandem mass spectrometry | |
TW200801506A (en) | Method and device of identifying individuals | |
Orlando | Quantitative analysis of glycoprotein glycans | |
WO2004008480A3 (en) | Quantitative analysis via isotopically differentitated derivatization | |
Li et al. | Rapid determination of corticosterone in mouse plasma by ultra fast liquid chromatography‐tandem mass spectrometry | |
CN103175921B (zh) | 液相色谱串联质谱分析尿液中苯和甲苯四种代谢产物的方法 | |
Orlando | Quantitative glycomics | |
EP1327883A3 (en) | Combined metabolomic, proteomic and transcriptomic analysis from one, single sample and suitable statistical evaluation of data | |
Castro-Gamero et al. | Biomarker verification using selected reaction monitoring and shotgun proteomics | |
SE0004094D0 (sv) | A method for the quantification of carbohudrates | |
DE602004021193D1 (de) | Erstellung von digitalaufnahmen einzelner radialer immundiffusionstests |