ATE554391T1 - Verfahren zur analyse von metaboliten - Google Patents
Verfahren zur analyse von metabolitenInfo
- Publication number
- ATE554391T1 ATE554391T1 AT04804051T AT04804051T ATE554391T1 AT E554391 T1 ATE554391 T1 AT E554391T1 AT 04804051 T AT04804051 T AT 04804051T AT 04804051 T AT04804051 T AT 04804051T AT E554391 T1 ATE554391 T1 AT E554391T1
- Authority
- AT
- Austria
- Prior art keywords
- metabolites
- biological sample
- isotopically labeled
- sample
- determining
- Prior art date
Links
- 239000002207 metabolite Substances 0.000 title abstract 9
- 239000012472 biological sample Substances 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000523 sample Substances 0.000 abstract 2
- 230000000155 isotopic effect Effects 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
- G01N33/6851—Methods of protein analysis involving laser desorption ionisation mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6848—Methods of protein analysis involving mass spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/15—Non-radioactive isotope labels, e.g. for detection by mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/13—Tracers or tags
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
- Y10T436/144444—Glucose
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
- Y10T436/25625—Dilution
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03029370 | 2003-12-19 | ||
| PCT/EP2004/014450 WO2005059556A1 (en) | 2003-12-19 | 2004-12-17 | Method for analysing metabolites |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE554391T1 true ATE554391T1 (de) | 2012-05-15 |
Family
ID=34684550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04804051T ATE554391T1 (de) | 2003-12-19 | 2004-12-17 | Verfahren zur analyse von metaboliten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8420406B2 (de) |
| EP (1) | EP1695088B1 (de) |
| AT (1) | ATE554391T1 (de) |
| AU (1) | AU2004299949B2 (de) |
| CA (1) | CA2547755C (de) |
| DK (1) | DK1695088T3 (de) |
| ES (1) | ES2385330T3 (de) |
| WO (1) | WO2005059556A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2004299949B2 (en) | 2003-12-19 | 2011-11-24 | Max Planck Geselllschaft Zur Forderung Der Wissenschaften | Method for analysing metabolites |
| US20060200316A1 (en) * | 2005-03-01 | 2006-09-07 | Harin Kanani | Data correction, normalization and validation for quantitative high-throughput metabolomic profiling |
| US20090203145A1 (en) * | 2008-02-07 | 2009-08-13 | Min Huang | Methods for analysis of vitamins |
| WO2010065878A1 (en) * | 2008-12-05 | 2010-06-10 | C2N Diagnostics | Methods for measuring concentrations of biomolecules |
| US9459247B2 (en) * | 2010-03-29 | 2016-10-04 | Academia Sinica | Quantitative measurement of nano/micro particle endocytosis with cell mass spectrometry |
| WO2011139930A1 (en) * | 2010-05-01 | 2011-11-10 | Nms Labs | A method for clinically monitoring niacin and niacin metabolites in serum or plasma |
| US9606106B2 (en) | 2012-02-10 | 2017-03-28 | Children's Medical Center Corporation | NMR-based metabolite screening platform |
| US10607723B2 (en) * | 2016-07-05 | 2020-03-31 | University Of Kentucky Research Foundation | Method and system for identification of metabolites using mass spectra |
| CN110392830B (zh) * | 2017-02-24 | 2024-04-16 | 伊罗亚科技有限公司 | 用于改进的精度、鉴定和定量的iroa代谢组学工作流程 |
| CN107589194B (zh) * | 2017-11-02 | 2019-01-29 | 武汉迈特维尔生物科技有限公司 | 一种肺癌早期诊断用小分子标志物及在诊断方面的应用 |
| US20220137057A1 (en) * | 2019-03-08 | 2022-05-05 | Basf Se | Metabolic analysis method |
| KR102333499B1 (ko) * | 2019-06-17 | 2021-12-01 | 고려대학교 산학협력단 | 대사체 분석을 이용한 류마티스 관절염 중증도 예측 또는 구분용 바이오마커 |
| CN112697894A (zh) * | 2020-11-30 | 2021-04-23 | 重庆医科大学附属口腔医院 | 氨基酸同位素标记物的定量分析方法 |
| CN113514531B (zh) * | 2021-04-27 | 2022-10-25 | 清华大学 | 一种化合物的碎片离子预测方法及应用 |
| WO2025090085A1 (en) * | 2023-10-26 | 2025-05-01 | The Regents Of The University Of Colorado, A Body Corporate | System and method for nadome analysis |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9117634D0 (en) * | 1991-08-15 | 1991-10-02 | Evans Lloyd T | Method of treating plants or plant tissues |
| US6391649B1 (en) | 1999-05-04 | 2002-05-21 | The Rockefeller University | Method for the comparative quantitative analysis of proteins and other biological material by isotopic labeling and mass spectroscopy |
| US20030077572A1 (en) * | 2001-10-11 | 2003-04-24 | Abramson Fred P. | Quantitative differential display using isotope ratio monitoring |
| US20030180710A1 (en) * | 2002-03-22 | 2003-09-25 | Lee Wai-Nang Paul | Method of enhancing the efficiency of a pharmaceutical business |
| EP1545628A4 (de) * | 2002-09-16 | 2010-07-28 | Univ California | Biochemische verfahren zur messung der metabolischen fitness von geweben oder des gesamten organismus |
| US20050112706A1 (en) * | 2002-11-07 | 2005-05-26 | Susan Kasper | Diagnostic and prognostic methods for prostate cancers |
| US6872516B2 (en) * | 2003-04-16 | 2005-03-29 | Advanced Breath Diagnostics, Llc | Methods of producing carbon-13 labeled biomass |
| EP1686372A4 (de) | 2003-11-21 | 2009-04-01 | Eisai R&D Man Co Ltd | Quantifizierungsverfahren mit verwendung eines isotopenmarkierten inneren standards, analysesystem zur durchführung des quantifizierungsverfahrens sowie programm zum abbau davon |
| AU2004299949B2 (en) | 2003-12-19 | 2011-11-24 | Max Planck Geselllschaft Zur Forderung Der Wissenschaften | Method for analysing metabolites |
-
2004
- 2004-12-17 AU AU2004299949A patent/AU2004299949B2/en not_active Ceased
- 2004-12-17 AT AT04804051T patent/ATE554391T1/de active
- 2004-12-17 CA CA2547755A patent/CA2547755C/en not_active Expired - Fee Related
- 2004-12-17 DK DK04804051.3T patent/DK1695088T3/da active
- 2004-12-17 WO PCT/EP2004/014450 patent/WO2005059556A1/en not_active Ceased
- 2004-12-17 ES ES04804051T patent/ES2385330T3/es not_active Expired - Lifetime
- 2004-12-17 US US10/580,024 patent/US8420406B2/en not_active Expired - Fee Related
- 2004-12-17 EP EP04804051A patent/EP1695088B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1695088B1 (de) | 2012-04-18 |
| AU2004299949A1 (en) | 2005-06-30 |
| US8420406B2 (en) | 2013-04-16 |
| WO2005059556A1 (en) | 2005-06-30 |
| US20070141712A1 (en) | 2007-06-21 |
| AU2004299949B2 (en) | 2011-11-24 |
| EP1695088A1 (de) | 2006-08-30 |
| CA2547755A1 (en) | 2005-06-30 |
| CA2547755C (en) | 2014-06-03 |
| ES2385330T3 (es) | 2012-07-23 |
| DK1695088T3 (da) | 2012-06-25 |
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