DK168785B1 - Fremgangsmåde til fremstilling af en bærer ladet med lipofilt biologisk aktivt stof på basis af rekonstitueret LDL - Google Patents

Fremgangsmåde til fremstilling af en bærer ladet med lipofilt biologisk aktivt stof på basis af rekonstitueret LDL Download PDF

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Publication number
DK168785B1
DK168785B1 DK077787A DK77787A DK168785B1 DK 168785 B1 DK168785 B1 DK 168785B1 DK 077787 A DK077787 A DK 077787A DK 77787 A DK77787 A DK 77787A DK 168785 B1 DK168785 B1 DK 168785B1
Authority
DK
Denmark
Prior art keywords
ldl
biologically active
active substance
lyophilized
reconstituted
Prior art date
Application number
DK077787A
Other languages
Danish (da)
English (en)
Other versions
DK77787D0 (da
DK77787A (da
Inventor
Michele Masquelier
Curt Peterson
Mikael Ros
Mats Rudling
Sigurd Vitols
Original Assignee
Oncholab Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncholab Ab filed Critical Oncholab Ab
Publication of DK77787D0 publication Critical patent/DK77787D0/da
Publication of DK77787A publication Critical patent/DK77787A/da
Application granted granted Critical
Publication of DK168785B1 publication Critical patent/DK168785B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1275—Lipoproteins; Chylomicrons; Artificial HDL, LDL, VLDL, protein-free species thereof; Precursors thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK077787A 1985-06-17 1987-02-16 Fremgangsmåde til fremstilling af en bærer ladet med lipofilt biologisk aktivt stof på basis af rekonstitueret LDL DK168785B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8502998A SE456136B (sv) 1985-06-17 1985-06-17 Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein)
SE8502998 1985-06-17
SE8600291 1986-06-17
PCT/SE1986/000291 WO1986007540A1 (en) 1985-06-17 1986-06-17 Method for the preparation of a macromolecular carrier loaded with a biologically active substance, product thus obtained and use thereof

Publications (3)

Publication Number Publication Date
DK77787D0 DK77787D0 (da) 1987-02-16
DK77787A DK77787A (da) 1987-02-16
DK168785B1 true DK168785B1 (da) 1994-06-13

Family

ID=20360603

Family Applications (1)

Application Number Title Priority Date Filing Date
DK077787A DK168785B1 (da) 1985-06-17 1987-02-16 Fremgangsmåde til fremstilling af en bærer ladet med lipofilt biologisk aktivt stof på basis af rekonstitueret LDL

Country Status (11)

Country Link
US (1) US4868158A (sv)
EP (1) EP0229100B1 (sv)
JP (1) JPS62502549A (sv)
AT (1) ATE67412T1 (sv)
AU (1) AU583402B2 (sv)
DE (1) DE3681578D1 (sv)
DK (1) DK168785B1 (sv)
FI (1) FI86802C (sv)
NO (1) NO169048C (sv)
SE (1) SE456136B (sv)
WO (1) WO1986007540A1 (sv)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2609399A1 (fr) * 1987-01-13 1988-07-15 Ire Celltarg Sa Procede d'incorporation d'un ou plusieurs principes actifs lipophiles dans des lipoproteines, lipoproteines obtenues et composition pharmaceutique les contenant
FR2664500B1 (fr) * 1990-07-13 1994-10-28 Lille Ii Universite Droit Sant Procede de preparation d'une lipoproteine modifiee par incorporation d'une substance active lipophile, lipoproteine modifiee ainsi obtenue et composition pharmaceutique ou cosmetique la contenant.
WO1993008842A1 (en) * 1991-11-08 1993-05-13 Somatogen, Inc. Hemoglobins as drug delivery agents
AU3892593A (en) * 1992-04-08 1993-11-18 Paavo Kai Johannes Kinnunen Composition for therapeutic or diagnostic use, process for its preparation and its use
NZ275054A (en) * 1993-11-08 1997-04-24 Peptide Delivery Systems Pty L Diagnosing atherosclerosis or coronary artery disease using labelled composition which mimics essential features of an exogenous lipoprotein
AU690592B2 (en) * 1993-11-08 1998-04-30 Peptide Delivery Systems Pty Ltd Labelled diagnostic compositions and methods of their use
US5652339A (en) * 1993-12-31 1997-07-29 Rotkreuzstiftung Zentrallaboratorium Method of producing reconstituted lipoproteins
US6610321B2 (en) 1996-07-03 2003-08-26 University Of Pittsburgh Emulsion formulations for hydrophilic active agents
AUPP032097A0 (en) * 1997-11-11 1997-12-04 Peptide Delivery Systems Pty Ltd Improved labelled diagnostic compositions and methods of their use
US6514523B1 (en) 2000-02-14 2003-02-04 Ottawa Heart Institute Research Corporation Carrier particles for drug delivery and process for preparation
US20090110739A1 (en) * 2007-05-15 2009-04-30 University Of North Texas Health Science Center At Forth Worth Targeted cancer chemotherapy using synthetic nanoparticles
WO2010057203A2 (en) 2008-11-17 2010-05-20 The Board Of Regents Of The University Of Texas System Hdl particles for delivery of nucleic acids
US20160346219A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
FI20215508A1 (sv) 2020-04-09 2021-10-10 Niemelae Erik Johan Mimetiska nanopartiklar för att förhindra spridningen och för att sänka infektionsgraden av nya coronavirus

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ180199A (en) * 1976-03-04 1978-11-13 New Zealand Dev Finance Method of testing for the presence of elevated plasma liprotein concentration
US4186192A (en) * 1978-12-18 1980-01-29 Cutter Laboratories, Inc. Stabilized immune serum globulin
US4440679A (en) * 1980-03-05 1984-04-03 Cutter Laboratories, Inc. Pasteurized therapeutically active protein compositions
US4356117A (en) * 1980-10-23 1982-10-26 U.S. Govt., Dept. Of Health & Human Services Chemical modifications of proteins which induce new receptor specificities and therefore elicit new effects in cells
JPS5967228A (ja) * 1982-10-07 1984-04-16 Green Cross Corp:The 寒冷不溶性グロブリンの凍結乾燥方法
US4478829A (en) * 1983-04-28 1984-10-23 Armour Pharmaceutical Company Pharmaceutical preparation containing purified fibronectin
NZ208241A (en) * 1984-05-22 1987-09-30 John Stephen Ayers Purification of blood plasma or serum: selective removal of (very) low density lipoproteins (ldl and vldl)
EP0238645A1 (en) * 1985-10-03 1987-09-30 Biotechnology Research Partners, Ltd. Novel lipoprotein-based drug-delivery systems

Also Published As

Publication number Publication date
US4868158A (en) 1989-09-19
NO169048B (no) 1992-01-27
AU583402B2 (en) 1989-04-27
SE8502998L (sv) 1986-12-18
FI870644A (fi) 1987-02-16
WO1986007540A1 (en) 1986-12-31
JPS62502549A (ja) 1987-10-01
FI86802B (fi) 1992-07-15
EP0229100B1 (en) 1991-09-18
FI870644A0 (fi) 1987-02-16
SE456136B (sv) 1988-09-12
NO169048C (no) 1992-05-06
NO870545D0 (no) 1987-02-11
JPH0586935B2 (sv) 1993-12-14
FI86802C (sv) 1992-10-26
NO870545L (no) 1987-02-11
AU5996886A (en) 1987-01-13
ATE67412T1 (de) 1991-10-15
DE3681578D1 (de) 1991-10-24
DK77787D0 (da) 1987-02-16
DK77787A (da) 1987-02-16
SE8502998D0 (sv) 1985-06-17
EP0229100A1 (en) 1987-07-22

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