DK168516B1 - Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr - Google Patents

Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr Download PDF

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Publication number
DK168516B1
DK168516B1 DK147086A DK147086A DK168516B1 DK 168516 B1 DK168516 B1 DK 168516B1 DK 147086 A DK147086 A DK 147086A DK 147086 A DK147086 A DK 147086A DK 168516 B1 DK168516 B1 DK 168516B1
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DK
Denmark
Prior art keywords
agonist
treatment
inhibitor
antiandrogen
biosynthesis
Prior art date
Application number
DK147086A
Other languages
Danish (da)
English (en)
Other versions
DK147086D0 (da
DK147086A (da
Inventor
Fernand Labrie
Alain Belanger
Andre Dupont
Original Assignee
Fernand Labrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/636,883 external-priority patent/US4775660A/en
Priority claimed from US06/699,711 external-priority patent/US4659695A/en
Priority claimed from US06/699,710 external-priority patent/US5023234A/en
Priority claimed from US06/699,702 external-priority patent/US4666885A/en
Application filed by Fernand Labrie filed Critical Fernand Labrie
Publication of DK147086D0 publication Critical patent/DK147086D0/da
Publication of DK147086A publication Critical patent/DK147086A/da
Application granted granted Critical
Publication of DK168516B1 publication Critical patent/DK168516B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
DK147086A 1984-08-02 1986-04-01 Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr DK168516B1 (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US06/636,883 US4775660A (en) 1984-08-02 1984-08-02 Treatment of breast cancer by combination therapy
US63688384 1984-08-02
US69971185 1985-02-08
US69970285 1985-02-08
US06/699,711 US4659695A (en) 1985-02-08 1985-02-08 Method of treatment of prostate cancer
US06/699,710 US5023234A (en) 1985-02-08 1985-02-08 Combination male breast cancer therapy
US69971085 1985-02-08
US06/699,702 US4666885A (en) 1985-02-08 1985-02-08 Combination therapy for treatment of female breast cancer
US8501454 1985-08-02
PCT/US1985/001454 WO1986001105A1 (fr) 1984-08-02 1985-08-02 Composition pharmaceutique pour le traitement de cancers dependant d'hormones

Publications (3)

Publication Number Publication Date
DK147086D0 DK147086D0 (da) 1986-04-01
DK147086A DK147086A (da) 1986-04-01
DK168516B1 true DK168516B1 (da) 1994-04-11

Family

ID=27505215

Family Applications (1)

Application Number Title Priority Date Filing Date
DK147086A DK168516B1 (da) 1984-08-02 1986-04-01 Sæt til kombinationsterapi af visse kønshormonafhængige cancertyper hos et varmblodet dyr

Country Status (8)

Country Link
EP (1) EP0195015B1 (fr)
JP (1) JPH0680016B2 (fr)
AT (1) ATE75947T1 (fr)
AU (1) AU594309B2 (fr)
DE (2) DE3590389T1 (fr)
DK (1) DK168516B1 (fr)
IE (1) IE58836B1 (fr)
WO (1) WO1986001105A1 (fr)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012488A (en) * 1987-07-31 1989-02-02 Syntex (U.S.A.) Inc. Combination therapy with lhrh antagonist analogs and 19nor progestational steroids
DE3733478A1 (de) * 1987-10-01 1989-04-13 Schering Ag Antigestagen- und antioestrogenwirksame verbindungen zur geburtseinleitung und zum schwangerschaftsabbruch sowie zur behandlung gynaekologischer stoerungen und hormonabhaengiger tumore
HU199694B (en) * 1988-05-10 1990-03-28 Innofinance Altalanos Innovaci Process for producing citostatic pharmaceutical compositions containing gonadoliberin derivatives
US5686465A (en) * 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
US5204337A (en) * 1988-10-31 1993-04-20 Endorecherche Inc. Estrogen nucleus derivatives for use in inhibition of sex steroid activity
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5364847A (en) * 1989-03-10 1994-11-15 Endorecherche Inhibitors of sex steroid biosynthesis and methods for their production and use
US5372996A (en) * 1989-03-10 1994-12-13 Endorecherche, Inc. Method of treatment of androgen-related diseases
US5595985A (en) * 1989-03-10 1997-01-21 Endorecherche Inc. Combination therapy for prophylaxis and/or treatment of benign prostatic hyperplasia
WO1990010462A1 (fr) * 1989-03-10 1990-09-20 Endorecherche Inc. Therapie combinee pour le traitement de maladies sensibles a l'×strogene
DE3921059A1 (de) * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
ES2189784T3 (es) * 1989-07-07 2003-07-16 Endorech Inc Procedimiento para el tratamiento de enfermedades relacionadas con adrogenos.
DK0943328T3 (da) * 1989-07-07 2004-10-18 Endorech Inc Kombinationsterapi til profylakse og/eller behandling af godartet prostatahyperplasi
US4990538A (en) * 1989-08-23 1991-02-05 Harris Adrian L Use of toremifene and its metabolites for the reversal of multidrug resistance of cancer cells against cytotoxic drugs
HU222501B1 (hu) * 1991-06-28 2003-07-28 Endorecherche Inc. MPA-t vagy MGA-t tartalmazó nyújtott hatóanyag-felszabadulású gyógyászati készítmény és eljárás előállítására
ZA924811B (en) * 1991-06-28 1993-12-29 Endorecherche Inc Controlled release systems and low dose androgens
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
WO1993023053A1 (fr) * 1992-05-21 1993-11-25 Endorecherche Inc. INHIBITEURS D'ACTIVITE DE LA TESTOSTERONE 5α-REDUCTASE
ZA961564B (en) * 1995-02-28 1997-08-27 Lilly Co Eli Methods of inhibiting ovarian cancer.
JPH08253417A (ja) * 1995-02-28 1996-10-01 Eli Lilly & Co 脳又はｃｎｓのエストロゲン陽性腫瘍抑制用製剤
CN1429104A (zh) 1998-03-11 2003-07-09 内部研究股份有限公司 5型和3型17β－羟基类固醇脱氢酶的抑制剂及其用法
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) * 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
DE60239207D1 (de) * 2001-08-10 2011-03-31 Takeda Pharmaceutical Gnrh-agonistische kombinationsmittel
PE20030703A1 (es) 2001-09-06 2003-08-21 Schering Corp Inhibidores de la 17b-hidroxiesteroide deshidrogenasa tipo 3
CA2463626C (fr) 2001-10-17 2011-05-24 Schering Corporation Piperidine- et piperazineacetamines en tant qu'inhibiteurs de 17beta-hydroxysteroide deshydrogenase de type 3 servant a traiter des maladies dependantes des androgenes
ATE469886T1 (de) 2002-11-18 2010-06-15 Schering Corp 17beta-hydroxysteroid dehydrogenase typ-3 hemmer zur behandlung von androgen abhängigen erkrankungen
CA2509758A1 (fr) 2002-12-17 2004-07-22 Schering Corporation Inhibiteurs de 17 beta-hydroxysteroide deshydrogenase de type 3 pour le traitement de maladies androgeno-dependantes
GB0513702D0 (en) 2005-07-04 2005-08-10 Sterix Ltd Compound
GB0722779D0 (en) 2007-11-20 2008-01-02 Sterix Ltd Compound
CN115862804B (zh) * 2022-11-25 2023-12-19 成都诺医德医学检验实验室有限公司 双药联用的联合用药的推荐方法及装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4329364A (en) * 1974-09-11 1982-05-11 Schering Corporation Antiandrogenic agents and methods for the treatment of androgen dependent disease states
FR2329276A1 (fr) * 1975-10-29 1977-05-27 Roussel Uclaf Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
DE2921593C2 (de) * 1979-05-28 1984-02-02 Gränges Nyby AB, Nybybruk Verfahren und Vorrichtung zum Weiterzerkleinern von hydriertem, grobstückigem Material, insbes. Schrott aus Titan oder dessen Legierungen
ZA822247B (en) * 1981-04-03 1983-11-30 Lilly Co Eli Benzothiophene compounds and process for preparing them

Also Published As

Publication number Publication date
IE58836B1 (en) 1993-11-17
DE3586053D1 (de) 1992-06-17
EP0195015B1 (fr) 1992-05-13
JPH0680016B2 (ja) 1994-10-12
DE3590389T1 (de) 1986-08-28
DK147086D0 (da) 1986-04-01
WO1986001105A1 (fr) 1986-02-27
DK147086A (da) 1986-04-01
ATE75947T1 (de) 1992-05-15
JPS62500451A (ja) 1987-02-26
EP0195015A1 (fr) 1986-09-24
AU4728285A (en) 1986-03-07
AU594309B2 (en) 1990-03-08
IE851929L (en) 1986-02-02

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PBP Patent lapsed
B1 Patent granted (law 1993)
PUP Patent expired