DK1675961T3 - Fremgangsmåde til identifikation og/eller validering af receptortyrosinkinaseinhibitorer - Google Patents

Fremgangsmåde til identifikation og/eller validering af receptortyrosinkinaseinhibitorer

Info

Publication number
DK1675961T3
DK1675961T3 DK03753198T DK03753198T DK1675961T3 DK 1675961 T3 DK1675961 T3 DK 1675961T3 DK 03753198 T DK03753198 T DK 03753198T DK 03753198 T DK03753198 T DK 03753198T DK 1675961 T3 DK1675961 T3 DK 1675961T3
Authority
DK
Denmark
Prior art keywords
tyrosine kinase
receptor tyrosine
host cells
validating
identifying
Prior art date
Application number
DK03753198T
Other languages
English (en)
Inventor
Tea Gunde
Catherine Berset
Alcide Barberis
Original Assignee
Oncalis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncalis Ag filed Critical Oncalis Ag
Application granted granted Critical
Publication of DK1675961T3 publication Critical patent/DK1675961T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK03753198T 2003-10-24 2003-10-24 Fremgangsmåde til identifikation og/eller validering af receptortyrosinkinaseinhibitorer DK1675961T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CH2003/000694 WO2005040413A1 (en) 2003-10-24 2003-10-24 Method for the identification and/or validation of receptor tyrosine kinase inhibitors

Publications (1)

Publication Number Publication Date
DK1675961T3 true DK1675961T3 (da) 2009-02-23

Family

ID=34468779

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03753198T DK1675961T3 (da) 2003-10-24 2003-10-24 Fremgangsmåde til identifikation og/eller validering af receptortyrosinkinaseinhibitorer

Country Status (11)

Country Link
US (1) US7566528B2 (da)
EP (1) EP1675961B1 (da)
JP (1) JP2007508801A (da)
AT (1) ATE411395T1 (da)
AU (1) AU2003271489B2 (da)
CA (1) CA2544074A1 (da)
DE (1) DE60324207D1 (da)
DK (1) DK1675961T3 (da)
IL (1) IL175097A0 (da)
NZ (1) NZ547398A (da)
WO (1) WO2005040413A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60324207D1 (de) 2003-10-24 2008-11-27 Oncalis Ag Verfahren zur identifizierung und/oder validierung von rezeptortyrosinkinase-inhibitoren
WO2005069872A2 (en) * 2004-01-15 2005-08-04 Washington University High throughput pharmaceutical screening using drosophila
US20060156421A1 (en) * 2004-06-18 2006-07-13 Cagan Ross L High throughput screening methods for anti-metastatic compounds
EP1715059A1 (en) * 2005-04-21 2006-10-25 Esbatech AG Method for the identification of possibly harmful receptor tyrosine kinase (RTK) mutations and of inhibitors or medication directed against RTK mutants
WO2006111035A1 (en) * 2005-04-21 2006-10-26 Oncalis Ag Method for the identification of possibly harmful receptor tyrosine kinase (rtk) mutations and of inhibitors or medication directed against rtk mutantstitle
DK2671954T3 (da) * 2006-01-20 2018-08-13 Cell Signaling Technology Inc Translokation og mutant ROS-kinase i human ikke-småcellet lungekarcinom
JP5392992B2 (ja) * 2007-03-30 2014-01-22 アズワン株式会社 自己リン酸化受容体のアゴニスト、アンタゴニストのスクリーニング方法、遺伝子組換え酵母
WO2009094148A2 (en) * 2008-01-22 2009-07-30 Biogen Idec Ma Inc. Ron antibodies and uses thereof
GB0900425D0 (en) * 2009-01-12 2009-02-11 Ucb Pharma Sa Biological products
KR101433057B1 (ko) 2012-03-07 2014-09-23 한국과학기술원 빛에 의해 ｒｔｋ 신호전달을 활성화하는 융합단백질 및 그의 용도
EP2789630A1 (en) 2013-04-09 2014-10-15 EngMab AG Bispecific antibodies against CD3e and ROR1
US10231965B2 (en) 2014-02-20 2019-03-19 Ignyta, Inc. Molecules for administration to ROS1 mutant cancer cells
DK3137114T3 (da) 2014-04-30 2021-01-25 Pfizer Anti-PTK7-antistof-lægemiddelkonjugater
CA2963692A1 (en) 2014-10-09 2016-04-14 Engmab Ag Bispecific antibodies against cd3epsilon and ror1
KR102595599B1 (ko) 2014-12-02 2023-11-02 이그니타, 인코포레이티드 신경모세포종의 치료를 위한 병용
WO2016196141A1 (en) * 2015-05-29 2016-12-08 Ignyta, Inc. Compositions and methods for treating patients with rtk mutant cells
KR20180096621A (ko) 2015-12-18 2018-08-29 이그니타, 인코포레이티드 암의 치료용 조합물
IL271759B2 (en) 2017-07-19 2024-01-01 Ignyta Inc Pharmaceutical preparations that include anthraxtinib
JP7311498B2 (ja) 2017-10-17 2023-07-19 イグナイタ インコーポレイテッド 薬学的組成物および剤形

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3482493A (en) * 1992-01-22 1993-09-01 New England Deaconess Hospital Novel protein tyrosine kinases
US6051397A (en) * 1993-11-16 2000-04-18 Max Planck Gesellschaft Zur Forderung Der Wissenschaften DNA encoding MCK-10, a novel receptor tyrosine kinase
US5573994A (en) 1994-05-13 1996-11-12 University Of Cincinnati Superabsorbent foams, and method for producing the same
US5573944A (en) * 1994-07-22 1996-11-12 President And Fellows Of Harvard College Yeast cell expressing heterologous receptor kinase
US6433154B1 (en) * 1997-06-12 2002-08-13 Bristol-Myers Squibb Company Functional receptor/kinase chimera in yeast cells
MXPA04008408A (es) * 2002-03-01 2004-11-29 Squibb Bristol Myers Co Mamiferos no humanos, transgenicos, que expresan receptores de la tirosina cinasa activados constitutivamente.
EP1495329B1 (en) * 2002-04-18 2006-03-29 Esbatech AG Method for the identification of modulators of a secretase activity
DE60324207D1 (de) 2003-10-24 2008-11-27 Oncalis Ag Verfahren zur identifizierung und/oder validierung von rezeptortyrosinkinase-inhibitoren

Also Published As

Publication number Publication date
EP1675961A1 (en) 2006-07-05
DE60324207D1 (de) 2008-11-27
ATE411395T1 (de) 2008-10-15
JP2007508801A (ja) 2007-04-12
EP1675961B1 (en) 2008-10-15
AU2003271489B2 (en) 2009-02-19
US20050239049A1 (en) 2005-10-27
CA2544074A1 (en) 2005-05-06
US7566528B2 (en) 2009-07-28
WO2005040413A1 (en) 2005-05-06
AU2003271489A1 (en) 2005-05-11
IL175097A0 (en) 2006-08-20
NZ547398A (en) 2008-10-31

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