DK166756B1 - Farmaceutisk praeparat indeholdende phenindamin (2,3,4,9-tetrahydro-2-methyl-9-phenyl-1h-indeno(2,1-c)pyridin) kombineret med et analgetikum - Google Patents

Farmaceutisk praeparat indeholdende phenindamin (2,3,4,9-tetrahydro-2-methyl-9-phenyl-1h-indeno(2,1-c)pyridin) kombineret med et analgetikum Download PDF

Info

Publication number
DK166756B1
DK166756B1 DK372786A DK372786A DK166756B1 DK 166756 B1 DK166756 B1 DK 166756B1 DK 372786 A DK372786 A DK 372786A DK 372786 A DK372786 A DK 372786A DK 166756 B1 DK166756 B1 DK 166756B1
Authority
DK
Denmark
Prior art keywords
phenindamine
approx
wax
composition according
wax matrix
Prior art date
Application number
DK372786A
Other languages
Danish (da)
English (en)
Other versions
DK372786D0 (da
DK372786A (da
Inventor
Luidoslava V Shtohryn
David Peters
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of DK372786D0 publication Critical patent/DK372786D0/da
Publication of DK372786A publication Critical patent/DK372786A/da
Application granted granted Critical
Publication of DK166756B1 publication Critical patent/DK166756B1/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/16Otologicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK372786A 1986-04-15 1986-08-05 Farmaceutisk praeparat indeholdende phenindamin (2,3,4,9-tetrahydro-2-methyl-9-phenyl-1h-indeno(2,1-c)pyridin) kombineret med et analgetikum DK166756B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/852,471 US4820523A (en) 1986-04-15 1986-04-15 Pharmaceutical composition
US85247186 1986-04-15

Publications (3)

Publication Number Publication Date
DK372786D0 DK372786D0 (da) 1986-08-05
DK372786A DK372786A (da) 1987-10-16
DK166756B1 true DK166756B1 (da) 1993-07-12

Family

ID=25313433

Family Applications (1)

Application Number Title Priority Date Filing Date
DK372786A DK166756B1 (da) 1986-04-15 1986-08-05 Farmaceutisk praeparat indeholdende phenindamin (2,3,4,9-tetrahydro-2-methyl-9-phenyl-1h-indeno(2,1-c)pyridin) kombineret med et analgetikum

Country Status (12)

Country Link
US (1) US4820523A (de)
EP (1) EP0241615B1 (de)
JP (1) JPH0621067B2 (de)
AT (1) ATE67407T1 (de)
AU (1) AU569431B2 (de)
CA (1) CA1267605A (de)
DE (1) DE3681582D1 (de)
DK (1) DK166756B1 (de)
ES (1) ES2001391A6 (de)
FI (1) FI863362A (de)
NZ (1) NZ217189A (de)
ZA (1) ZA865923B (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA882783B (en) * 1987-06-10 1988-10-20 Warner-Lambert Company Process for preparing a pharmaceutical composition
JP2729494B2 (ja) * 1988-11-08 1998-03-18 武田薬品工業株式会社 安定な細粒剤
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
IE65045B1 (en) * 1990-04-28 1995-10-04 Takeda Chemical Industries Ltd Granulated preparations and method of producing the same
DE4102629A1 (de) * 1991-01-30 1992-08-06 Bayer Ag Pharmazeutischer kaugummi mit acetylsalicylsaeure
US5380535A (en) * 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
US5405617A (en) * 1991-11-07 1995-04-11 Mcneil-Ppc, Inc. Aliphatic or fatty acid esters as a solventless carrier for pharmaceuticals
US5348747A (en) * 1992-03-05 1994-09-20 American Home Products Corporation Pharmaceutical coating sugars
DE4216756C2 (de) * 1992-05-21 1994-08-25 Pharmatrans Sanaq Ag 2-Arylpropionsäure-Zubereitungen und Verfahren zu ihrer Herstellung
US5260340A (en) * 1992-11-19 1993-11-09 Baranowitz Steven A Prevention and amelioration of acetaminophen toxicity with beta-carotene
AU6086794A (en) * 1993-02-18 1994-09-14 Warner-Lambert Company Cold/sinus preparation consisting of phenindamine tartarate with or without therapeutic agents
IL109460A (en) 1993-05-10 1998-03-10 Euro Celtique Sa Controlled release formulation comprising tramadol
US5455045A (en) * 1993-05-13 1995-10-03 Syntex (U.S.A.) Inc. High dose formulations
ZA944949B (en) * 1993-07-12 1995-04-05 Smithkline Beecham Corp Matrix-entrapped beadlet preparation
US5891471A (en) 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
CN1062129C (zh) * 1995-09-14 2001-02-21 徐荣祥 药物基质及其用途
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
US7232924B2 (en) * 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
EP1412324A4 (de) * 2001-06-11 2004-09-29 Xenoport Inc Aminosäurekonjugate, die anhaltende systemische konzentrationen von gaba-analoga ergeben
AU2002345664C1 (en) * 2001-06-11 2008-03-06 Xenoport, Inc. Prodrugs of gaba analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2004052841A1 (en) 2002-12-06 2004-06-24 Xenoport, Inc. Carbidopa prodrugs and uses thereof
US20040162351A1 (en) * 2002-12-11 2004-08-19 Gallop Mark A. Orally administered dosage forms of fused GABA analog prodrugs having reduced toxicity
WO2004089289A2 (en) * 2003-03-31 2004-10-21 Xenoport, Inc. Treating or preventing hot flashes using prodrugs of gaba analogs
US7109239B2 (en) * 2003-08-20 2006-09-19 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
EP2354120A1 (de) 2003-08-20 2011-08-10 XenoPort, Inc. Synthese von Acyloxyalkylcarbamat-Prodrugs und Zwischenprodukten davon
CA2537837A1 (en) * 2003-09-11 2005-03-24 Xenoport, Inc. Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
WO2005027850A2 (en) * 2003-09-17 2005-03-31 Xenoport, Inc. Treating or preventing restless legs syndrome using prodrugs of gaba analogs
US9492541B2 (en) * 2004-09-14 2016-11-15 Sovereign Pharmaceuticals, Llc Phenylepherine containing dosage form
US20060029664A1 (en) * 2004-08-04 2006-02-09 Sovereign Pharmaceuticals, Ltd. Dosage form containing carbetapentane and another drug
US20060128676A1 (en) * 2004-07-13 2006-06-15 Pharmacofore, Inc. Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
WO2006050471A2 (en) * 2004-11-03 2006-05-11 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
US7494985B2 (en) * 2004-11-03 2009-02-24 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
WO2006050514A1 (en) 2004-11-04 2006-05-11 Xenoport, Inc. Gabapentin prodrug sustained release oral dosage forms
US9241502B2 (en) * 2005-01-28 2016-01-26 Adm Alliance Nutrition Animal feed compositions capable of reducing the incidence of fescue toxicosis in mammals
US7529255B2 (en) * 2005-04-21 2009-05-05 Microsoft Corporation Peer-to-peer multicasting using multiple transport protocols
WO2007002013A2 (en) 2005-06-20 2007-01-04 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
US20070049626A1 (en) * 2005-08-26 2007-03-01 Tran Pierre V Treating premature ejaculation using gabapentin and pregabalin prodrugs
EP2402037B8 (de) 2006-05-26 2019-12-04 Signature Therapeutics, Inc. Kontrollierte Freisetzung phenolischer Opioide
US20090074917A2 (en) * 2006-07-26 2009-03-19 Remington Direct Lp Low-calorie, no laxation bulking system
US7585996B2 (en) * 2006-09-15 2009-09-08 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
CN101652133A (zh) * 2006-12-08 2010-02-17 克塞诺波特公司 Gaba类似物的前药用于治疗疾病的用途
WO2011028234A1 (en) * 2009-09-04 2011-03-10 Xenoport, Inc. Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
DK2621282T3 (da) 2010-09-28 2020-05-04 Univ California Gaba-agonister i behandlingen af forstyrrelser forbundet med metabolisk syndrom og gaba-kombinationer i behandling eller profylakse af type i diabetes
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
GB2556817B (en) 2015-10-01 2019-11-06 Elysium Therapeutics Inc Polysubunit opioid prodrugs resistant to overdose and abuse
CA3056239C (en) 2017-03-17 2023-09-12 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
KR20210013081A (ko) 2018-05-14 2021-02-03 엑스진 파마슈티컬 인크. 나프록센 및 프레가발린의 1-(아실옥시)-알킬 카르바메이트 약물 복합체의 결정형

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2470108A (en) * 1949-05-17 Heterocyclic amines
US3402240A (en) * 1957-06-25 1968-09-17 Pfizer & Co C Medicinal tablet and process of making same
US2993836A (en) * 1958-02-20 1961-07-25 Dow Chemical Co Sustained release tablets
US3062720A (en) * 1959-05-20 1962-11-06 Philips Roxane Sustained release pharmaceutical tablet
US3400197A (en) * 1965-01-26 1968-09-03 Robins Co Inc A H Compressible sustained release pharmaceutical tablet lipid-colloidal silica gel matrix fragment granules
US3577514A (en) * 1968-06-10 1971-05-04 Pfizer Sustained release pharmaceutical tablets
JPS50155614A (de) * 1974-06-07 1975-12-16
DE3024416C2 (de) * 1980-06-28 1982-04-15 Gödecke AG, 1000 Berlin Verfahren zur Herstellung von Arzneimitteln mit retardierter Wirkstoff-Freisetzung
JPS6045846B2 (ja) * 1980-11-14 1985-10-12 理研ビタミン株式会社 L−アスコルビン酸製剤およびその製造法
US4704284A (en) * 1982-08-12 1987-11-03 Pfizer Inc. Long-acting matrix tablet formulations
US4643892A (en) * 1983-07-20 1987-02-17 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates of analgesics
US4647450A (en) * 1983-07-20 1987-03-03 Warner-Lambert Company Chewing gum compositions containing magnesium trisilicate absorbates
US4632821A (en) * 1983-07-20 1986-12-30 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates of decongestants
US4642231A (en) * 1983-07-20 1987-02-10 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates of antihistamines
US4650663A (en) * 1983-07-20 1987-03-17 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates of antitussives
US4581232A (en) * 1983-07-20 1986-04-08 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates
US4552899A (en) * 1984-04-09 1985-11-12 Analgesic Associates Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs
US4590062A (en) * 1984-04-16 1986-05-20 Tech Trade Corp. Dry direct compression compositions for controlled release dosage forms
US4752485A (en) * 1984-10-05 1988-06-21 Warner-Lambert Company Novel sweetener delivery systems
US4747881A (en) * 1985-02-05 1988-05-31 Warner-Lambert Company Ingestible aggregate and delivery system prepared therefrom
US4753800A (en) * 1985-10-04 1988-06-28 Warner-Lambert Company Medicament adsorbates and their preparation

Also Published As

Publication number Publication date
JPH0621067B2 (ja) 1994-03-23
FI863362A0 (fi) 1986-08-20
EP0241615B1 (de) 1991-09-18
US4820523A (en) 1989-04-11
EP0241615A1 (de) 1987-10-21
AU6113786A (en) 1987-10-22
DK372786D0 (da) 1986-08-05
NZ217189A (en) 1989-11-28
ZA865923B (en) 1987-03-25
DK372786A (da) 1987-10-16
DE3681582D1 (de) 1991-10-24
JPS62242619A (ja) 1987-10-23
ATE67407T1 (de) 1991-10-15
AU569431B2 (en) 1988-01-28
FI863362A (fi) 1987-10-16
ES2001391A6 (es) 1988-05-16
CA1267605A (en) 1990-04-10

Similar Documents

Publication Publication Date Title
DK166756B1 (da) Farmaceutisk praeparat indeholdende phenindamin (2,3,4,9-tetrahydro-2-methyl-9-phenyl-1h-indeno(2,1-c)pyridin) kombineret med et analgetikum
US5656296A (en) Dual control sustained release drug delivery systems and methods for preparing same
EP0219458B1 (de) Arzneistoffadsorbate und deren Herstellung
DK168267B1 (da) Lægemiddel-adsorbat og fremgangsmåde til dets fremstilling
DK167047B1 (da) Laegemiddel-adsorbat, dets fremstilling og laegemiddelpraeparat, konfektureprodukt og tyggegummiprodukt indeholdende laegemiddeladsorbatet
AU2016246580B2 (en) Multicomponent gummy compositions with hard core
US4647450A (en) Chewing gum compositions containing magnesium trisilicate absorbates
EP0774955B1 (de) Verbessertes bioadhäsives pharmazeutisches abgabesystem
US4797288A (en) Novel drug delivery system
US4929508A (en) Novel drug delivery system for antitussives
US4935242A (en) Novel drug delivery system for expectorants
US4647459A (en) Confectionery compositions containing magnesium trisilicate adsorbates
US4894233A (en) Novel drug delivery system for decongestants
JPS61126015A (ja) 新規な薬物放出系
JP2006503046A (ja) 放出が改変された経口製剤
US4933183A (en) Novel drug delivery system for mineral supplements
JPS62289527A (ja) 薬用吸着質の製法
US4643898A (en) Magnesium trisilicate suitable for preparation of medicament adsorbates of nutritional supplements and laxatives
EP0295212A2 (de) Verfahren zur Herstellung einer pharmazeutischen Zusammensetzung
Jadhav et al. A comprehensive review on: medicated chewing gum
US4643892A (en) Magnesium trisilicate suitable for preparation of medicament adsorbates of analgesics
US5626878A (en) Reduction of electrostatic forces between magnesium trisilicate adsorbates
Conway Solid dosage forms
CA2194168C (en) Improved bioadhesive pharmaceutical delivery system
JUNO et al. PHARMACEUTICAL SCIENCES

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed