DK1661913T3 - Bioaktive peptider udledt fra æggehvideprotein gennem enzymatisk hydrolyse - Google Patents
Bioaktive peptider udledt fra æggehvideprotein gennem enzymatisk hydrolyseInfo
- Publication number
- DK1661913T3 DK1661913T3 DK04766983T DK04766983T DK1661913T3 DK 1661913 T3 DK1661913 T3 DK 1661913T3 DK 04766983 T DK04766983 T DK 04766983T DK 04766983 T DK04766983 T DK 04766983T DK 1661913 T3 DK1661913 T3 DK 1661913T3
- Authority
- DK
- Denmark
- Prior art keywords
- activity
- egg white
- treatment
- bioactive peptides
- peptides
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 102000002322 Egg Proteins Human genes 0.000 title abstract 2
- 108010000912 Egg Proteins Proteins 0.000 title abstract 2
- 230000000975 bioactive effect Effects 0.000 title abstract 2
- 230000007071 enzymatic hydrolysis Effects 0.000 title 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 title 1
- 102100030988 Angiotensin-converting enzyme Human genes 0.000 abstract 3
- 230000002401 inhibitory effect Effects 0.000 abstract 3
- 206010020772 Hypertension Diseases 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 2
- 230000003276 anti-hypertensive effect Effects 0.000 abstract 2
- 230000003078 antioxidant effect Effects 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- UUUHXMGGBIUAPW-UHFFFAOYSA-N 1-[1-[2-[[5-amino-2-[[1-[5-(diaminomethylideneamino)-2-[[1-[3-(1h-indol-3-yl)-2-[(5-oxopyrrolidine-2-carbonyl)amino]propanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]pyrrolidine-2-carbon Chemical compound C1CCC(C(=O)N2C(CCC2)C(O)=O)N1C(=O)C(C(C)CC)NC(=O)C(CCC(N)=O)NC(=O)C1CCCN1C(=O)C(CCCN=C(N)N)NC(=O)C1CCCN1C(=O)C(CC=1C2=CC=CC=C2NC=1)NC(=O)C1CCC(=O)N1 UUUHXMGGBIUAPW-UHFFFAOYSA-N 0.000 abstract 1
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 abstract 1
- 108090000882 Peptidyl-Dipeptidase A Proteins 0.000 abstract 1
- 241000700159 Rattus Species 0.000 abstract 1
- 239000000470 constituent Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 235000014103 egg white Nutrition 0.000 abstract 1
- 210000000969 egg white Anatomy 0.000 abstract 1
- 230000002255 enzymatic effect Effects 0.000 abstract 1
- 235000013373 food additive Nutrition 0.000 abstract 1
- 239000002778 food additive Substances 0.000 abstract 1
- 235000012041 food component Nutrition 0.000 abstract 1
- 239000005417 food ingredient Substances 0.000 abstract 1
- 235000013376 functional food Nutrition 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 229940127557 pharmaceutical product Drugs 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/04—Animal proteins
- A23J3/08—Dairy proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8103—Exopeptidase (E.C. 3.4.11-19) inhibitors
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
- A23J3/341—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes of animal proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/01—Hydrolysed proteins; Derivatives thereof
- A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/465—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from birds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
- C07K14/77—Ovalbumin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biophysics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200301829A ES2253036B1 (es) | 2003-07-31 | 2003-07-31 | Peptidos bioactivos derivados de proteinas de la clara de huevo mediante hidrolisis enzimatica. |
| PCT/ES2004/070059 WO2005012355A1 (es) | 2003-07-31 | 2004-07-23 | Péptidos bioactivos derivados de proteínas de la clara de huevo mediante hidrólisis enzimática |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1661913T3 true DK1661913T3 (da) | 2008-07-07 |
Family
ID=34112522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04766983T DK1661913T3 (da) | 2003-07-31 | 2004-07-23 | Bioaktive peptider udledt fra æggehvideprotein gennem enzymatisk hydrolyse |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8227207B2 (de) |
| EP (1) | EP1661913B1 (de) |
| JP (1) | JP2007523045A (de) |
| AT (1) | ATE388166T1 (de) |
| DE (1) | DE602004012289T2 (de) |
| DK (1) | DK1661913T3 (de) |
| ES (2) | ES2253036B1 (de) |
| WO (1) | WO2005012355A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006273850A (ja) * | 2005-03-04 | 2006-10-12 | Pharma Foods International Co Ltd | 血中乳酸値上昇抑制組成物及びそれを含有する飲食品 |
| ES2329316B1 (es) * | 2005-05-23 | 2010-10-14 | Consejo Superior Investig. Cientificas | Obtencion y propiedades antihipertensivas de peptidos derivados de proteinas de clara de huevo. |
| JP2008156344A (ja) * | 2006-11-27 | 2008-07-10 | Q P Corp | 生体内抗酸化材、生体内抗酸化用食品組成物及び生体内抗酸化用医薬品組成物、並びに肝機能障害抑制材、肝機能障害抑制用食品組成物及び肝機能障害抑制用医薬品組成物 |
| EP2322041A4 (de) | 2008-08-01 | 2016-03-30 | Naturex Sa | Gewinnung von kakaoextrakten mit hohem gehalt an biologisch aktiven peptiden mit ace- und pep-enzymhemmwirkung |
| WO2010106437A1 (en) * | 2009-03-20 | 2010-09-23 | The Governors Of The University Of Alberta | Peptides that inhibit angiotensin converting enzyme and peptides with antioxidant activity purified from ovotransferrin and methods of producing and using the same |
| KR20130059335A (ko) * | 2010-04-07 | 2013-06-05 | 고쿠리츠 다이가쿠 호진 교토 다이가쿠 | 생리 활성 펩티드 |
| EP2548458B1 (de) * | 2011-07-22 | 2013-07-03 | HPF Nutraceutics S.r.L. | Lupinen-abgeleitete Verbindungen mit hypotonischer Wirkung und Verfahrensprozess zu ihrer Herstellung |
| KR101510178B1 (ko) | 2013-05-27 | 2015-04-10 | 대한민국 | 항산화 펩타이드를 포함하는 조성물 |
| WO2015082741A1 (es) * | 2013-12-04 | 2015-06-11 | Consejo Superior De Investigaciones Cientificas (Csic) | Uso de productos bioactivos multifuncionales derivados de la hidrólisis enzimática de proteínas de clara de huevo para el tratamiento del síndrome metabólico |
| CN107205432A (zh) | 2014-11-11 | 2017-09-26 | 克莱拉食品公司 | 用于生成卵清蛋白的方法和组合物 |
| CN104814439B (zh) * | 2015-05-27 | 2017-09-29 | 吉林大学 | 一种蛋清小肽降压营养粉及制备方法 |
| KR102056348B1 (ko) | 2018-05-28 | 2019-12-16 | 주식회사 바이오프로후즈 | 난백 가수분해물의 제조방법 및 이의 용도 |
| CN109485696B (zh) * | 2018-11-06 | 2020-10-23 | 渤海大学 | 一种克服肠道降解的膜肽酶抑制肽 |
| EP3997118A4 (de) | 2019-07-11 | 2023-07-19 | Clara Foods Co. | Proteinzusammensetzungen und verbrauchbare produkte daraus |
| US10927360B1 (en) | 2019-08-07 | 2021-02-23 | Clara Foods Co. | Compositions comprising digestive enzymes |
| CN110628856A (zh) * | 2019-10-17 | 2019-12-31 | 武汉普诺金生物科技股份有限公司 | 一种降血压小分子肽及其制备方法和应用 |
| CN112616925A (zh) * | 2020-12-30 | 2021-04-09 | 光明乳业股份有限公司 | 一种双蛋白发酵乳及其制备方法 |
| EP4046649A1 (de) | 2021-02-22 | 2022-08-24 | Bioseutica B.V. | Ovotransferrine zur verwendung bei der behandlung von eisenmangelanämie |
| CN116444611B (zh) * | 2022-11-30 | 2024-06-04 | 内蒙古伊利实业集团股份有限公司 | 乳源活性肽tdplfkg及其制备方法与应用 |
| CN117264018B (zh) * | 2023-09-26 | 2024-04-09 | 南京工业大学 | 一种鸽蛋清中功能肽的制备及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5470970A (en) * | 1991-02-28 | 1995-11-28 | Dana-Farber Cancer Institute, Inc. | Maspin, a serpin with tumor suppresing activity |
| JP3129523B2 (ja) * | 1992-05-29 | 2001-01-31 | 日本合成化学工業株式会社 | 新規ペプチド及びその製造方法 |
| GB9310472D0 (en) * | 1993-05-20 | 1993-07-07 | Univ Warwick | Phenylalanine-free protein and dna coding thereof |
| JPH09263597A (ja) * | 1996-03-29 | 1997-10-07 | Taiyo Kagaku Co Ltd | 新規ペプチド |
| JP3770659B2 (ja) * | 1996-07-23 | 2006-04-26 | 日本合成化学工業株式会社 | 新規ペプチド及びその製造方法 |
| US5935968A (en) * | 1997-03-17 | 1999-08-10 | Merck & Co., Inc. | Methods for treating polycystic ovary syndrome |
| CN1367875A (zh) * | 1999-07-08 | 2002-09-04 | 斯特思吉生物技术公司 | 活体外th1一样反应的诱导方法 |
| US6514941B1 (en) | 1999-12-10 | 2003-02-04 | Campina Melkunie B.V. | Method of preparing a casein hydrolysate enriched in anti-hypertensive peptides |
| AU2001259625A1 (en) | 2000-05-08 | 2001-11-20 | Davisco Foods International, Inc. | Enzymatic treatment of whey proteins for the production of antihypertensive peptides, the resulting products and treatment of hypertension in mammals |
| US7265208B2 (en) * | 2001-05-01 | 2007-09-04 | The Regents Of The University Of California | Fusion molecules and treatment of IgE-mediated allergic diseases |
-
2003
- 2003-07-31 ES ES200301829A patent/ES2253036B1/es not_active Withdrawn - After Issue
-
2004
- 2004-07-23 EP EP04766983A patent/EP1661913B1/de not_active Not-in-force
- 2004-07-23 DE DE602004012289T patent/DE602004012289T2/de active Active
- 2004-07-23 WO PCT/ES2004/070059 patent/WO2005012355A1/es active IP Right Grant
- 2004-07-23 DK DK04766983T patent/DK1661913T3/da active
- 2004-07-23 AT AT04766983T patent/ATE388166T1/de not_active IP Right Cessation
- 2004-07-23 JP JP2006521598A patent/JP2007523045A/ja active Pending
- 2004-07-23 ES ES04766983T patent/ES2303090T3/es active Active
-
2006
- 2006-01-30 US US11/343,263 patent/US8227207B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2253036B1 (es) | 2007-07-16 |
| DE602004012289T2 (de) | 2009-09-03 |
| WO2005012355B1 (es) | 2005-03-24 |
| ATE388166T1 (de) | 2008-03-15 |
| ES2303090T3 (es) | 2008-08-01 |
| US20060280804A1 (en) | 2006-12-14 |
| EP1661913B1 (de) | 2008-03-05 |
| EP1661913A1 (de) | 2006-05-31 |
| JP2007523045A (ja) | 2007-08-16 |
| US8227207B2 (en) | 2012-07-24 |
| WO2005012355A1 (es) | 2005-02-10 |
| DE602004012289D1 (de) | 2008-04-17 |
| ES2253036A1 (es) | 2006-05-16 |
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