DK164939C - Fremgangsmaade til fremstilling af n-alkylerede dipeptider eller estere deraf - Google Patents

Fremgangsmaade til fremstilling af n-alkylerede dipeptider eller estere deraf

Info

Publication number
DK164939C
DK164939C DK440584A DK440584A DK164939C DK 164939 C DK164939 C DK 164939C DK 440584 A DK440584 A DK 440584A DK 440584 A DK440584 A DK 440584A DK 164939 C DK164939 C DK 164939C
Authority
DK
Denmark
Prior art keywords
alkyl
aryl
carbon atoms
substituted
atoms
Prior art date
Application number
DK440584A
Other languages
English (en)
Other versions
DK440584A (da
DK164939B (da
DK440584D0 (da
Inventor
Volker Teetz
Hans Wissmann
Hansjoerg Urbach
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK440584D0 publication Critical patent/DK440584D0/da
Publication of DK440584A publication Critical patent/DK440584A/da
Publication of DK164939B publication Critical patent/DK164939B/da
Application granted granted Critical
Publication of DK164939C publication Critical patent/DK164939C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK440584A 1983-09-16 1984-09-14 Fremgangsmaade til fremstilling af n-alkylerede dipeptider eller estere deraf DK164939C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833333454 DE3333454A1 (de) 1983-09-16 1983-09-16 Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3333454 1983-09-16

Publications (4)

Publication Number Publication Date
DK440584D0 DK440584D0 (da) 1984-09-14
DK440584A DK440584A (da) 1985-03-17
DK164939B DK164939B (da) 1992-09-14
DK164939C true DK164939C (da) 1993-02-01

Family

ID=6209235

Family Applications (1)

Application Number Title Priority Date Filing Date
DK440584A DK164939C (da) 1983-09-16 1984-09-14 Fremgangsmaade til fremstilling af n-alkylerede dipeptider eller estere deraf

Country Status (21)

Country Link
US (1) US5068351A (da)
EP (1) EP0135182B1 (da)
JP (1) JPH0798835B2 (da)
KR (1) KR910007574B1 (da)
AT (1) ATE35997T1 (da)
AU (1) AU576782B2 (da)
CA (1) CA1338163C (da)
DE (2) DE3333454A1 (da)
DK (1) DK164939C (da)
ES (1) ES535917A0 (da)
FI (1) FI80464C (da)
GR (1) GR80369B (da)
HU (1) HU201565B (da)
IE (1) IE57798B1 (da)
IL (1) IL72947A (da)
MA (1) MA20225A1 (da)
MX (1) MX172737B (da)
NO (1) NO167743C (da)
NZ (1) NZ209543A (da)
PT (1) PT79202B (da)
ZA (1) ZA847257B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3333456A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von carbonsaeureamidgruppen enthaltenden verbindungen, insbesondere von peptiden
DE3408923A1 (de) * 1984-03-12 1985-09-26 Hoechst Ag, 6230 Frankfurt Carboxyalkyldipeptidderivate, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
KR900009154B1 (ko) * 1985-09-16 1990-12-22 쉐링 코포레이션 고혈압 치료제, 이를 포함하는 약제학적 조성물 및 이들의 제조방법
EP0331609A3 (de) * 1988-01-27 1992-07-01 Hoechst Aktiengesellschaft Angiotensin-Converting-Enzym-Hemmstoffe mit psychotroper Wirkung
IL92441A (en) * 1988-12-07 1993-05-13 Tanabe Seiyaku Co Imidazole containing peptides, their preparation and pharmaceutical compositions containing them
JP2581770Y2 (ja) * 1993-01-20 1998-09-24 川崎重工業 株式会社 航空機洗浄装置
ES2122941B1 (es) * 1997-05-29 1999-07-01 Esteve Quimica Sa Procedimiento para la obtencion de quinapril clorhidrato y solvatos utiles para el aislamiento y purificacion de quinapril clorhidrato.
CA2363658C (en) * 2001-11-21 2005-12-13 Brantford Chemicals Inc. Improved process for the preparation of ramipril
BRPI0517663A (pt) * 2004-11-05 2008-10-14 King Pharmaceuticals Res & Dev composição farmacêutica, método para preparar a mesma, produto, e, método para tratar distúrbios cardiovasculares

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5572169A (en) * 1978-11-27 1980-05-30 Tanabe Seiyaku Co Ltd Isoquinoline derivative and its preparation
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
DE2901843A1 (de) * 1979-01-18 1980-07-31 Hoechst Ag Verfahren zur herstellung von carbonsaeureamiden und peptiden
US4294832A (en) * 1979-04-28 1981-10-13 Tanabe Seiyaku Co., Ltd. Tetrahydroisoquinoline compounds and a pharmaceutical composition thereof
FR2491469A1 (fr) * 1980-10-02 1982-04-09 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
IE52663B1 (en) * 1980-04-02 1988-01-20 Warner Lambert Co Substituted acyl derivatives of octahydro-1h-indole-2-carboxylic acids
US4350704A (en) * 1980-10-06 1982-09-21 Warner-Lambert Company Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acids
DE3177130D1 (de) * 1980-08-30 1990-01-11 Hoechst Ag Aminosaeurederivate, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung.
IL63813A0 (en) * 1980-09-17 1981-12-31 Univ Miami Carboxyalkyl peptides and thioethers and ethers of peptides,antihypertensive compositions and methods for their use
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
ZA817261B (en) * 1980-10-23 1982-09-29 Schering Corp Carboxyalkyl dipeptides,processes for their production and pharmaceutical compositions containing them
DE19575012I2 (de) * 1980-10-23 2002-01-24 Schering Corp Carboxyalkyl-Dipeptide Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
US4374847A (en) * 1980-10-27 1983-02-22 Ciba-Geigy Corporation 1-Carboxyalkanoylindoline-2-carboxylic acids
GB2086390B (en) * 1980-11-03 1984-06-06 Ciba Geigy Ag 1-carboxy-azaalkanoylindoline-2-carboxylic acids process for their manufacture pharmaceutical preparations containing these compounds and their therapeutic application
DE3101427A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von carbonsaeureamidgruppen enthaltenden verbindungen, insbesondere von peptiden"
IN156096B (da) * 1981-03-19 1985-05-11 Usv Pharma Corp
US4820729A (en) * 1981-03-30 1989-04-11 Rorer Pharmaceutical Corporation N-substituted-amido-amino acids
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
DE3210496A1 (de) * 1982-03-23 1983-10-06 Hoechst Ag Neue derivate bicyclischer aminsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung
DE3211676A1 (de) * 1982-03-30 1983-10-06 Hoechst Ag Neue derivate von cycloalka (c) pyrrol-carbonsaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue cycloalka (c) pyrrol-carbonsaeuren als zwischenstufen und verfahren zu deren herstellung
DE3315464A1 (de) * 1983-04-28 1984-10-31 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3322530A1 (de) * 1983-06-23 1985-01-10 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren
DE3333456A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von carbonsaeureamidgruppen enthaltenden verbindungen, insbesondere von peptiden
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern

Also Published As

Publication number Publication date
NO167743B (no) 1991-08-26
KR910007574B1 (ko) 1991-09-28
DK440584A (da) 1985-03-17
CA1338163C (en) 1996-03-12
US5068351A (en) 1991-11-26
DK164939B (da) 1992-09-14
ATE35997T1 (de) 1988-08-15
IL72947A0 (en) 1984-12-31
PT79202B (de) 1986-09-10
ES8600219A1 (es) 1985-10-01
IE842350L (en) 1985-03-16
NO843662L (no) 1985-03-18
HUT36145A (en) 1985-08-28
KR850002251A (ko) 1985-05-10
FI843590L (fi) 1985-03-17
NZ209543A (en) 1989-04-26
MA20225A1 (fr) 1985-04-01
EP0135182A2 (de) 1985-03-27
FI80464C (fi) 1990-06-11
HU201565B (en) 1990-11-28
AU576782B2 (en) 1988-09-08
GR80369B (en) 1985-01-11
NO167743C (no) 1991-12-04
DE3333454A1 (de) 1985-04-11
AU3307084A (en) 1985-03-21
DK440584D0 (da) 1984-09-14
DE3472962D1 (en) 1988-09-01
EP0135182B1 (de) 1988-07-27
JPH0798835B2 (ja) 1995-10-25
MX172737B (es) 1994-01-10
EP0135182A3 (en) 1986-03-05
ES535917A0 (es) 1985-10-01
PT79202A (de) 1984-10-01
JPS6089497A (ja) 1985-05-20
FI843590A0 (fi) 1984-09-13
FI80464B (fi) 1990-02-28
IE57798B1 (en) 1993-04-07
IL72947A (en) 1989-02-28
ZA847257B (en) 1985-05-29

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ATE25244T1 (de) Neue derivate bicyclischer aminosaeuren, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie neue bicyclische aminosaeuren als zwischenstufen und verfahren zu deren herstellung.

Legal Events

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PUP Patent expired