DK1648880T3 - Terapeutiske midler, der kan anvendes til behandling af smerte - Google Patents

Terapeutiske midler, der kan anvendes til behandling af smerte

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Publication number
DK1648880T3
DK1648880T3 DK04779721.2T DK04779721T DK1648880T3 DK 1648880 T3 DK1648880 T3 DK 1648880T3 DK 04779721 T DK04779721 T DK 04779721T DK 1648880 T3 DK1648880 T3 DK 1648880T3
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Denmark
Prior art keywords
substituted pyridyl
pyridyl compound
animal
effective amount
disclosed
Prior art date
Application number
DK04779721.2T
Other languages
Danish (da)
English (en)
Inventor
Donald J Kyle
Qun Sun
Original Assignee
Euro Celtique Sa
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Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Application granted granted Critical
Publication of DK1648880T3 publication Critical patent/DK1648880T3/da

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
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US8030310B2 (en) 2011-10-04
AU2004261666A1 (en) 2005-02-10
CY1112129T1 (el) 2015-11-04
PL1648880T3 (pl) 2010-06-30
ATE455773T1 (de) 2010-02-15
EP2275420A1 (en) 2011-01-19
SI1942106T1 (sl) 2012-01-31
HRP20100229T1 (hr) 2010-05-31
EP1648880A1 (en) 2006-04-26
US7696208B2 (en) 2010-04-13
EP1942106B1 (en) 2011-09-14
CY1110004T1 (el) 2015-01-14
EP1942106A1 (en) 2008-07-09
HK1093489A1 (en) 2007-03-02
CN1832935A (zh) 2006-09-13
US20100240675A1 (en) 2010-09-23
HK1120799A1 (en) 2009-04-09
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PT1942106E (pt) 2011-12-22
WO2005012287A1 (en) 2005-02-10
EP1648880B1 (en) 2010-01-20
MXPA06001331A (es) 2006-05-04
SI1648880T1 (sl) 2010-05-31
US20060258669A1 (en) 2006-11-16
DK1942106T3 (da) 2011-12-19
DE602004025244D1 (de) 2010-03-11
PL1942106T3 (pl) 2012-02-29
CA2534088C (en) 2011-01-11
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