DK164107C - Konjugater af vinblastin eller derivater deraf, fremgangsmaader til deres fremstilling og farmaceutiske praeparater indeholdende dem - Google Patents

Konjugater af vinblastin eller derivater deraf, fremgangsmaader til deres fremstilling og farmaceutiske praeparater indeholdende dem

Info

Publication number
DK164107C
DK164107C DK473286A DK473286A DK164107C DK 164107 C DK164107 C DK 164107C DK 473286 A DK473286 A DK 473286A DK 473286 A DK473286 A DK 473286A DK 164107 C DK164107 C DK 164107C
Authority
DK
Denmark
Prior art keywords
conjugates
image
group
derivatives
vinblastin
Prior art date
Application number
DK473286A
Other languages
English (en)
Other versions
DK473286D0 (da
DK473286A (da
DK164107B (da
Inventor
Andre Benoit Lenon Trouet
Kandukuri Sivaprasade Bush Rao
Jean-Alfred Alphonse Hannart
Jean-Paul Dejonghe
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU86157A external-priority patent/LU86157A1/fr
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of DK473286D0 publication Critical patent/DK473286D0/da
Publication of DK473286A publication Critical patent/DK473286A/da
Publication of DK164107B publication Critical patent/DK164107B/da
Application granted granted Critical
Publication of DK164107C publication Critical patent/DK164107C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6805Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a vinca alkaloid

Landscapes

  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
DK473286A 1985-11-12 1986-10-03 Konjugater af vinblastin eller derivater deraf, fremgangsmaader til deres fremstilling og farmaceutiske praeparater indeholdende dem DK164107C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
LU86157A LU86157A1 (fr) 1985-11-12 1985-11-12 Nouveau procede de fabrication de conjugues de la vinblastine et de ses derives
LU86157 1985-11-12
EP86870042 1986-04-08
EP86870042A EP0222722B1 (fr) 1985-11-12 1986-04-08 Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués

Publications (4)

Publication Number Publication Date
DK473286D0 DK473286D0 (da) 1986-10-03
DK473286A DK473286A (da) 1987-05-13
DK164107B DK164107B (da) 1992-05-11
DK164107C true DK164107C (da) 1992-10-05

Family

ID=26106792

Family Applications (1)

Application Number Title Priority Date Filing Date
DK473286A DK164107C (da) 1985-11-12 1986-10-03 Konjugater af vinblastin eller derivater deraf, fremgangsmaader til deres fremstilling og farmaceutiske praeparater indeholdende dem

Country Status (6)

Country Link
AT (1) ATE89567T1 (da)
AU (1) AU577206B2 (da)
DK (1) DK164107C (da)
GR (1) GR862436B (da)
HU (1) HU196217B (da)
OA (1) OA08424A (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2508905B1 (da) * 1981-07-01 1984-01-27 Roussel Uclaf
EP0178683B1 (en) * 1984-10-19 1989-08-09 Nihon Medi-Physics Co., Ltd. Imunoassay for estriol-3-sulfate
IL82579A0 (en) * 1986-05-27 1987-11-30 Lilly Co Eli Immunoglobulin conjugates
US5094849A (en) * 1988-08-08 1992-03-10 Eli Lilly And Company Cytotoxic antibody conjugates of hydrazide derivatized vinca analogs via simple organic linkers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR81790B (da) * 1983-04-29 1984-12-12 Omnichem Sa

Also Published As

Publication number Publication date
ATE89567T1 (de) 1993-06-15
HU196217B (en) 1988-10-28
AU577206B2 (en) 1988-09-15
DK473286D0 (da) 1986-10-03
GR862436B (en) 1986-12-23
AU6340186A (en) 1988-04-14
OA08424A (fr) 1988-06-30
HUT42493A (en) 1987-07-28
DK473286A (da) 1987-05-13
DK164107B (da) 1992-05-11

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Legal Events

Date Code Title Description
PBP Patent lapsed