ATE24917T1 - Peptide-derivate, deren herstellung und verwendung als elastasehemmende mittel. - Google Patents

Peptide-derivate, deren herstellung und verwendung als elastasehemmende mittel.

Info

Publication number
ATE24917T1
ATE24917T1 AT84400999T AT84400999T ATE24917T1 AT E24917 T1 ATE24917 T1 AT E24917T1 AT 84400999 T AT84400999 T AT 84400999T AT 84400999 T AT84400999 T AT 84400999T AT E24917 T1 ATE24917 T1 AT E24917T1
Authority
AT
Austria
Prior art keywords
ala
elastasic
agents
preparation
peptide derivatives
Prior art date
Application number
AT84400999T
Other languages
English (en)
Inventor
Ladislas Robert
William Hornebeck
Elemer Moczar
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE24917T1 publication Critical patent/ATE24917T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
AT84400999T 1983-05-16 1984-05-16 Peptide-derivate, deren herstellung und verwendung als elastasehemmende mittel. ATE24917T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8308052A FR2546164B1 (fr) 1983-05-16 1983-05-16 Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
EP84400999A EP0126009B1 (de) 1983-05-16 1984-05-16 Peptide-Derivate, deren Herstellung und Verwendung als elastasehemmende Mittel

Publications (1)

Publication Number Publication Date
ATE24917T1 true ATE24917T1 (de) 1987-01-15

Family

ID=9288874

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84400999T ATE24917T1 (de) 1983-05-16 1984-05-16 Peptide-derivate, deren herstellung und verwendung als elastasehemmende mittel.

Country Status (6)

Country Link
US (1) US4665053A (de)
EP (1) EP0126009B1 (de)
JP (1) JPS59219257A (de)
AT (1) ATE24917T1 (de)
DE (1) DE3462039D1 (de)
FR (1) FR2546164B1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0124317B1 (de) * 1983-04-27 1990-04-11 Ici Americas Inc. Prolin-Derivate
US4740588A (en) * 1986-08-07 1988-04-26 Washington University Novel substrate peptides
ZA897514B (en) * 1988-10-07 1990-06-27 Merrell Dow Pharma Novel peptidase inhibitors
US5736520A (en) * 1988-10-07 1998-04-07 Merrell Pharmaceuticals Inc. Peptidase inhibitors
FR2659327A1 (fr) * 1990-03-08 1991-09-13 Centre Nat Rech Scient Derives du benzisothiazolinone-1-dioxyde, utilisables comme inhibiteurs des elastases.
FR2676741A1 (fr) * 1991-05-22 1992-11-27 Morelle Jean Lipopolyaminoacides et lipopeptides vegetaux.
FR2710839B1 (fr) * 1993-10-08 1995-12-08 Rocher Yves Biolog Vegetale Composition cosmétique et méthode de traitement esthétique s'opposant au vieillissement de la peau.
US5614489A (en) * 1995-05-25 1997-03-25 Mohammadi; Fatemeh Method and composition for treating the skin
AU6103896A (en) * 1995-06-07 1996-12-30 Cytel Corporation Manufacture and purification of peptides
AU2002241664A1 (en) * 2000-12-29 2002-07-16 Kimberly-Clark Worldwide, Inc. Use of matrix metalloproteinase peptide substrate to lower the rate of extracellular matrix turnover
FR2826266B1 (fr) * 2001-06-26 2005-02-25 Oreal Composition cosmetique ou dermatologique comprenant une association entre un compose de la famille des n-acylaminoamides et au moins un inhibiteur de metalloproteinases matricielles
AU2003303607A1 (en) * 2002-12-30 2004-07-29 Jean-Noel Thorel Cutaneous metabolic bio-activator
ES2349972B1 (es) 2009-02-16 2011-11-24 Lipotec, S.A. Péptidos útiles en el tratamiento y/o cuidado de la piel, mucosas y/o cuero cabelludo y su uso en composiciones cosméticas o farmacéuticas.
KR101635618B1 (ko) * 2014-12-29 2016-07-08 한국해양대학교 산학협력단 피부노화 억제와 피부주름 개선 활성을 가지는 화합물
US20170319643A1 (en) 2016-05-05 2017-11-09 The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv Lipoprotein targeting protease inhibitors and uses
BR112018076309A8 (pt) * 2016-06-17 2022-06-28 Univ Erasmus Med Ct Rotterdam Compostos de geminóide e seus usos
TW202233647A (zh) * 2020-11-17 2022-09-01 挪威商霍夫賽思生物保健有限公司 呼吸治療

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL279057A (de) * 1900-01-01
DE1493807A1 (de) * 1962-07-04 1969-12-18 Hoffmann La Roche Verfahren zur Herstellung von Oligopeptidgemischen
FI40902B (de) * 1962-10-12 1969-03-31 Hoffmann La Roche
IL42124A (en) * 1972-05-02 1977-02-28 Kabi Ab Substrate for the determination of proteolytic enzymes
SE407058B (sv) * 1974-12-05 1979-03-12 Kabi Ab Nya kromogena enzymsubstrat for serinproteaser
GB1533129A (en) * 1975-10-23 1978-11-22 Sagami Chem Res Process for producing a peptide in the presence of an enzyme
DE2860893D1 (en) * 1977-06-20 1981-11-05 Ciba Geigy Ag Lipopeptides, process for their preparation and pharmaceutical compositions containing them
NZ189101A (en) * 1977-12-08 1984-07-06 Ortho Pharma Corp Polypeptides having the ability to induce differentiation of both th-1+ t-lymphocytes and bu-1+ b-lymphocytes;pharmaceutical compositions
EP0014815A3 (de) * 1978-12-20 1980-10-29 Ciba-Geigy Ag Peptidderivate, Verfahren zu deren Herstellung und Zwischenprodukte sowie pharmazeutische Präparate mit einer dieser Verbindungen
FR2460288A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux dipeptides, leur preparation et les medicaments qui les contiennent

Also Published As

Publication number Publication date
US4665053A (en) 1987-05-12
EP0126009A1 (de) 1984-11-21
DE3462039D1 (en) 1987-02-19
EP0126009B1 (de) 1987-01-14
FR2546164A1 (fr) 1984-11-23
JPS59219257A (ja) 1984-12-10
FR2546164B1 (fr) 1987-07-17

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee