DK1620373T3 - Apparat og fremgangsmåde til nucleofil fluorering - Google Patents

Apparat og fremgangsmåde til nucleofil fluorering

Info

Publication number
DK1620373T3
DK1620373T3 DK04731136T DK04731136T DK1620373T3 DK 1620373 T3 DK1620373 T3 DK 1620373T3 DK 04731136 T DK04731136 T DK 04731136T DK 04731136 T DK04731136 T DK 04731136T DK 1620373 T3 DK1620373 T3 DK 1620373T3
Authority
DK
Denmark
Prior art keywords
anion exchange
measurement
nucleophilic fluorination
fluoride ions
exchange device
Prior art date
Application number
DK04731136T
Other languages
English (en)
Inventor
Peter Maeding
Frank Fuechtner
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2003120552 external-priority patent/DE10320552A1/de
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of DK1620373T3 publication Critical patent/DK1620373T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/041Heterocyclic compounds
    • A61K51/044Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K51/0459Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nuclear Medicine (AREA)
  • Saccharide Compounds (AREA)
DK04731136T 2003-05-07 2004-05-05 Apparat og fremgangsmåde til nucleofil fluorering DK1620373T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2003120552 DE10320552A1 (de) 2003-05-07 2003-05-07 Vorrichtung und Verfahren zum nucleophilen Fluorieren
US46896303P 2003-05-09 2003-05-09
PCT/EP2004/004784 WO2004100490A2 (de) 2003-05-07 2004-05-05 Vorrichtung und verfahren zum nucleophilen fluorieren

Publications (1)

Publication Number Publication Date
DK1620373T3 true DK1620373T3 (da) 2008-07-28

Family

ID=33435959

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04731136T DK1620373T3 (da) 2003-05-07 2004-05-05 Apparat og fremgangsmåde til nucleofil fluorering

Country Status (11)

Country Link
US (1) US7482498B2 (da)
EP (1) EP1620373B1 (da)
JP (1) JP2006525279A (da)
AT (1) ATE390395T1 (da)
AU (1) AU2004237297B2 (da)
DE (1) DE502004006670D1 (da)
DK (1) DK1620373T3 (da)
ES (1) ES2305769T3 (da)
PL (1) PL1620373T3 (da)
PT (1) PT1620373E (da)
WO (1) WO2004100490A2 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200823170A (en) * 2006-09-06 2008-06-01 Nihon Mediphysics Co Ltd Process for producing radioactive fluorine labeled organic compound, and relevant synthetic apparatus and program
US8293208B2 (en) 2009-05-15 2012-10-23 The Governors Of The University Of Alberta Fluorinated fructose derivatives for PET imaging
JP5735519B2 (ja) * 2009-10-08 2015-06-17 ゼネラル・エレクトリック・カンパニイ マルチストリーム分光光度計モジュール
US9139316B2 (en) 2010-12-29 2015-09-22 Cardinal Health 414, Llc Closed vial fill system for aseptic dispensing
KR101245790B1 (ko) 2011-05-13 2013-03-20 성균관대학교산학협력단 방사성 화합물 합성장치
WO2013012813A1 (en) 2011-07-15 2013-01-24 Cardinal Health 414, Llc Modular cassette synthesis unit
WO2013012808A2 (en) * 2011-07-15 2013-01-24 Cardinal Health 414, Llc System for radiopharmaceutical preparation involving solid and liquid phase interactions
US9417332B2 (en) 2011-07-15 2016-08-16 Cardinal Health 414, Llc Radiopharmaceutical CZT sensor and apparatus
US20130102772A1 (en) 2011-07-15 2013-04-25 Cardinal Health 414, Llc Systems, methods and devices for producing, manufacturing and control of radiopharmaceuticals-full
US9523778B2 (en) 2011-09-30 2016-12-20 Ge Healthcare Limited Calibration and normalization systems and methods for radiopharmaceutical synthesizers
CN102744346B (zh) * 2012-07-17 2014-04-23 济宁科力光电产业有限责任公司 安全光幕的动态自检方法
KR101276741B1 (ko) 2012-10-22 2013-06-19 성균관대학교산학협력단 방사성 화합물 합성장치
CN109806822B (zh) * 2019-01-30 2021-07-30 杭州吉蕊科技有限公司 一种模块化、多功能的pet探针自动化合成系统

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3424525A1 (de) * 1984-07-04 1986-01-16 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verfahren zur herstellung von (pfeil hoch)1(pfeil hoch)(pfeil hoch)8(pfeil hoch)f-alkyl- und arylverbindungen durch halogenaustausch
JP3133251B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 陽イオン交換樹脂カラム上で、溶媒除去と加水分解反応を同時に行うfdg合成装置
JP3133252B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 三方切り替え活栓を組み込んだfdg合成装置
JP3279914B2 (ja) * 1996-03-29 2002-04-30 エヌケ−ケ−プラント建設株式会社 オンカラムfdg合成装置
US5932178A (en) * 1996-03-29 1999-08-03 Nkk Plant Engineering Corporation FDG synthesizer using columns
JPH11295494A (ja) * 1998-04-08 1999-10-29 Nippon Meji Physics Kk [f−18]−フッ化物イオンの製造方法
UY27003A1 (es) * 2000-11-06 2002-07-31 Schering Ag Productos radiofarmacéuticos para el diagnóstico de la enfermedad de alzheimer
EP1412951A2 (en) * 2001-06-13 2004-04-28 The Uni. Of Alberta, the Uni. of British Columbia, Carleton Uni., Simon Fraser Uni., the Uni. of Victoria, d.b.a. TRIUMF Apparatus and method for generating ?18 f-fluoride by ion beams
GB0305848D0 (en) * 2003-03-14 2003-04-16 Imaging Res Solutions Ltd Radiopharmaceutical generation system
CA2523189A1 (en) * 2003-04-22 2004-11-04 Molecular Technologies, Inc. System and method for synthesis of molecular imaging probes including fdg

Also Published As

Publication number Publication date
WO2004100490A3 (de) 2005-05-26
WO2004100490A2 (de) 2004-11-18
EP1620373A2 (de) 2006-02-01
EP1620373B1 (de) 2008-03-26
ATE390395T1 (de) 2008-04-15
US20090005617A1 (en) 2009-01-01
PT1620373E (pt) 2008-06-30
US7482498B2 (en) 2009-01-27
JP2006525279A (ja) 2006-11-09
AU2004237297B2 (en) 2010-04-08
AU2004237297A1 (en) 2004-11-18
PL1620373T3 (pl) 2008-09-30
ES2305769T3 (es) 2008-11-01
DE502004006670D1 (de) 2008-05-08

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