DK1613594T3 - 4-(2-Phenylsulfanyl-phenyl)-1,2,3,6-tetrahydropyridin derivater som serotonin-genoptagelseshæmmere - Google Patents
4-(2-Phenylsulfanyl-phenyl)-1,2,3,6-tetrahydropyridin derivater som serotonin-genoptagelseshæmmereInfo
- Publication number
- DK1613594T3 DK1613594T3 DK04725299T DK04725299T DK1613594T3 DK 1613594 T3 DK1613594 T3 DK 1613594T3 DK 04725299 T DK04725299 T DK 04725299T DK 04725299 T DK04725299 T DK 04725299T DK 1613594 T3 DK1613594 T3 DK 1613594T3
- Authority
- DK
- Denmark
- Prior art keywords
- phenylsulfanyl
- phenyl
- serotonin reuptake
- reuptake inhibitors
- tetrahydropyridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46026603P | 2003-04-04 | 2003-04-04 | |
DKPA200300518 | 2003-04-04 | ||
PCT/DK2004/000243 WO2004087662A1 (en) | 2003-04-04 | 2004-04-02 | 4-(2-phenylsulfanyl-phenyl)-1,2,3,6-tetrahydropyridine derivatives as serotonin reuptake inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1613594T3 true DK1613594T3 (da) | 2008-07-14 |
Family
ID=35432910
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04725299T DK1613594T3 (da) | 2003-04-04 | 2004-04-02 | 4-(2-Phenylsulfanyl-phenyl)-1,2,3,6-tetrahydropyridin derivater som serotonin-genoptagelseshæmmere |
Country Status (28)
Country | Link |
---|---|
US (1) | US20070173522A1 (de) |
EP (1) | EP1613594B1 (de) |
JP (1) | JP2006522029A (de) |
KR (1) | KR20060021825A (de) |
CN (1) | CN100384822C (de) |
AR (1) | AR043964A1 (de) |
AT (1) | ATE390413T1 (de) |
AU (1) | AU2004226319A1 (de) |
BR (1) | BRPI0408453A (de) |
CA (1) | CA2521172A1 (de) |
CL (1) | CL2004000730A1 (de) |
CO (1) | CO5700777A2 (de) |
DE (1) | DE602004012724T2 (de) |
DK (1) | DK1613594T3 (de) |
EA (1) | EA009282B1 (de) |
ES (1) | ES2301979T3 (de) |
HK (1) | HK1090051A1 (de) |
HR (1) | HRP20080243T3 (de) |
IS (1) | IS8007A (de) |
MX (1) | MXPA05010678A (de) |
NO (1) | NO20055205L (de) |
NZ (1) | NZ541944A (de) |
PL (1) | PL1613594T3 (de) |
PT (1) | PT1613594E (de) |
SI (1) | SI1613594T1 (de) |
UA (1) | UA81300C2 (de) |
WO (1) | WO2004087662A1 (de) |
ZA (1) | ZA200507182B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SI1626720T1 (sl) | 2003-04-04 | 2008-12-31 | Lundbeck & Co As H | Derivati 4-(2-fenilsulfanil-fenil)-piperidina kotzaviralci ponovnega vnosa serotonina |
EP2248524A3 (de) | 2004-08-25 | 2011-03-09 | Takeda Pharmaceutical Company Limited | Mittel zur prävention/behandlung von stressbedingter harninkontinenz und vorsorgeuntersuchungsverfahren dafür |
EP2018863B9 (de) | 2006-05-16 | 2015-02-18 | Takeda Pharmaceutical Company Limited | Kondensierte, heterocyclische Verbindung und ihre Verwendung |
EP2216023A4 (de) | 2007-11-15 | 2013-03-13 | Takeda Pharmaceutical | Kondensiertes pyridinderivat und seine verwendung |
UA98698C2 (en) * | 2008-03-03 | 2012-06-11 | Х. Луннбек А/С | Phenylsulfanylphenyl-piperidines and process for the preparation thereof |
US20120253036A1 (en) | 2009-12-11 | 2012-10-04 | Yukinori Nagakura | Agent for treating fibromyalgia |
EP2930171A1 (de) * | 2014-04-07 | 2015-10-14 | LEK Pharmaceuticals d.d. | Synthese von Vortioxetin über (2,4-Dimethylphenyl) (2-Iodophenyl)sulfan-Zwischenprodukt |
CN105294554B (zh) * | 2015-11-18 | 2017-11-07 | 乳源瑶族自治县大众药品贸易有限公司 | 苯基哌嗪衍生物及其使用方法和用途 |
WO2019131902A1 (ja) | 2017-12-27 | 2019-07-04 | 武田薬品工業株式会社 | 腹圧性尿失禁および便失禁の治療薬 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3803143A (en) * | 1969-09-08 | 1974-04-09 | Eisai Co Ltd | 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines |
US4018830A (en) * | 1969-09-22 | 1977-04-19 | Merck & Co., Inc. | Phenylthioaralkylamines |
US4055665A (en) * | 1974-11-25 | 1977-10-25 | Merck & Co., Inc. | Treating arrythmia with phenylthioaralkylamines |
US4066654A (en) * | 1975-04-16 | 1978-01-03 | G. D. Searle & Co. | 1-triarylalkyl-4-phenyl-4-piperidine carboxylic acids and derivatives |
US4056632A (en) * | 1975-07-21 | 1977-11-01 | Burroughs Wellcome Co. | 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use |
US4241071A (en) * | 1977-01-27 | 1980-12-23 | American Hoechst Corporation | Antidepressant (α-phenyl-2-tolyl)azacycloalkanes |
DE2802306A1 (de) * | 1977-01-27 | 1978-08-10 | Hoechst Ag | Azacycloalkane, azacycloalkene und ihre derivate |
US4198417A (en) * | 1979-01-10 | 1980-04-15 | American Hoechst Corporation | Phenoxyphenylpiperidines |
US4198419A (en) * | 1979-01-10 | 1980-04-15 | American Hoechst Corporation | Phenylthiophenylpiperidines |
GB8912971D0 (en) * | 1989-06-06 | 1989-07-26 | Wellcome Found | Halogen substituted diphenylsulfides |
US6410736B1 (en) * | 1999-11-29 | 2002-06-25 | Pfizer Inc. | Biaryl ether derivatives useful as monoamine reuptake inhibitors |
EE200200191A (et) * | 1999-10-13 | 2003-06-16 | Pfizer Products Inc. | Monoamiini taasomastamise inhibiitoritena kasulikud biarüüleetri derivaadid |
PT1246816E (pt) * | 1999-12-30 | 2004-08-31 | Lundbeck & Co As H | Derivados de fenilpiperazina substituidos sua preparacao e utilizacao |
US6436938B1 (en) * | 2001-01-22 | 2002-08-20 | Pfizer Inc. | Combination treatment for depression |
US20020107244A1 (en) * | 2001-02-02 | 2002-08-08 | Howard Harry R. | Combination treatment for depression |
UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
-
2004
- 2004-02-04 UA UAA200508779A patent/UA81300C2/uk unknown
- 2004-04-02 WO PCT/DK2004/000243 patent/WO2004087662A1/en active IP Right Grant
- 2004-04-02 NZ NZ541944A patent/NZ541944A/en unknown
- 2004-04-02 PL PL04725299T patent/PL1613594T3/pl unknown
- 2004-04-02 US US10/551,869 patent/US20070173522A1/en not_active Abandoned
- 2004-04-02 AT AT04725299T patent/ATE390413T1/de not_active IP Right Cessation
- 2004-04-02 JP JP2006504348A patent/JP2006522029A/ja active Pending
- 2004-04-02 BR BRPI0408453-5A patent/BRPI0408453A/pt not_active IP Right Cessation
- 2004-04-02 CA CA002521172A patent/CA2521172A1/en not_active Abandoned
- 2004-04-02 CL CL200400730A patent/CL2004000730A1/es unknown
- 2004-04-02 AU AU2004226319A patent/AU2004226319A1/en not_active Abandoned
- 2004-04-02 EP EP04725299A patent/EP1613594B1/de not_active Expired - Lifetime
- 2004-04-02 MX MXPA05010678A patent/MXPA05010678A/es active IP Right Grant
- 2004-04-02 DK DK04725299T patent/DK1613594T3/da active
- 2004-04-02 KR KR1020057018870A patent/KR20060021825A/ko not_active Application Discontinuation
- 2004-04-02 CN CNB2004800094713A patent/CN100384822C/zh not_active Expired - Fee Related
- 2004-04-02 ES ES04725299T patent/ES2301979T3/es not_active Expired - Lifetime
- 2004-04-02 AR ARP040101130A patent/AR043964A1/es not_active Application Discontinuation
- 2004-04-02 DE DE602004012724T patent/DE602004012724T2/de not_active Expired - Fee Related
- 2004-04-02 PT PT04725299T patent/PT1613594E/pt unknown
- 2004-04-02 ZA ZA200507182A patent/ZA200507182B/en unknown
- 2004-04-02 SI SI200430727T patent/SI1613594T1/sl unknown
- 2004-04-02 EA EA200501579A patent/EA009282B1/ru not_active IP Right Cessation
-
2005
- 2005-08-29 IS IS8007A patent/IS8007A/is unknown
- 2005-11-02 CO CO05111852A patent/CO5700777A2/es unknown
- 2005-11-04 NO NO20055205A patent/NO20055205L/no unknown
-
2006
- 2006-09-26 HK HK06110721A patent/HK1090051A1/xx not_active IP Right Cessation
-
2008
- 2008-06-03 HR HR20080243T patent/HRP20080243T3/xx unknown
Also Published As
Publication number | Publication date |
---|---|
NO20055205L (no) | 2005-11-04 |
CN100384822C (zh) | 2008-04-30 |
UA81300C2 (en) | 2007-12-25 |
IS8007A (is) | 2005-08-29 |
DE602004012724T2 (de) | 2009-04-09 |
ES2301979T3 (es) | 2008-07-01 |
JP2006522029A (ja) | 2006-09-28 |
AR043964A1 (es) | 2005-08-17 |
EP1613594B1 (de) | 2008-03-26 |
PL1613594T3 (pl) | 2008-09-30 |
WO2004087662A1 (en) | 2004-10-14 |
HRP20080243T3 (en) | 2009-04-30 |
NZ541944A (en) | 2008-05-30 |
PT1613594E (pt) | 2008-07-01 |
AU2004226319A1 (en) | 2004-10-14 |
ATE390413T1 (de) | 2008-04-15 |
CA2521172A1 (en) | 2004-10-14 |
BRPI0408453A (pt) | 2006-04-04 |
SI1613594T1 (sl) | 2008-08-31 |
KR20060021825A (ko) | 2006-03-08 |
US20070173522A1 (en) | 2007-07-26 |
ZA200507182B (en) | 2006-12-27 |
CO5700777A2 (es) | 2006-11-30 |
CN1777585A (zh) | 2006-05-24 |
EP1613594A1 (de) | 2006-01-11 |
DE602004012724D1 (de) | 2008-05-08 |
HK1090051A1 (en) | 2006-12-15 |
EA009282B1 (ru) | 2007-12-28 |
CL2004000730A1 (es) | 2005-02-18 |
MXPA05010678A (es) | 2005-12-12 |
EA200501579A1 (ru) | 2006-04-28 |
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