DK161254C - Fremgangsmaade til fremstilling af 1-formyl-derivater af dimere indol-dihydroindol-forbindelser - Google Patents
Fremgangsmaade til fremstilling af 1-formyl-derivater af dimere indol-dihydroindol-forbindelserInfo
- Publication number
- DK161254C DK161254C DK504882A DK504882A DK161254C DK 161254 C DK161254 C DK 161254C DK 504882 A DK504882 A DK 504882A DK 504882 A DK504882 A DK 504882A DK 161254 C DK161254 C DK 161254C
- Authority
- DK
- Denmark
- Prior art keywords
- dihydroindol
- indol
- dimers
- preparing
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines Containing Plant Substances (AREA)
- Peptides Or Proteins (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32166281 | 1981-11-16 | ||
| US06/321,662 US4375432A (en) | 1981-05-12 | 1981-11-16 | Method of preparing vincristine |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK504882A DK504882A (da) | 1983-05-17 |
| DK161254B DK161254B (da) | 1991-06-17 |
| DK161254C true DK161254C (da) | 1991-12-02 |
Family
ID=23251481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK504882A DK161254C (da) | 1981-11-16 | 1982-11-12 | Fremgangsmaade til fremstilling af 1-formyl-derivater af dimere indol-dihydroindol-forbindelser |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4375432A (el) |
| EP (1) | EP0079785B1 (el) |
| JP (1) | JPS5890591A (el) |
| KR (1) | KR860000488B1 (el) |
| CA (1) | CA1180328A (el) |
| DE (1) | DE3277200D1 (el) |
| DK (1) | DK161254C (el) |
| GB (1) | GB2109378B (el) |
| GR (1) | GR77791B (el) |
| HU (1) | HU189620B (el) |
| IE (1) | IE54172B1 (el) |
| IL (1) | IL67219A (el) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU190219B (en) * | 1984-01-06 | 1986-08-28 | Richter Gedeon Vegyeszeti Gyar Rt,Hu | Process for preparing in 3",7'-position cyclized dimer-cinca-alkaloid-derivatives |
| FR2582651B1 (fr) * | 1985-06-03 | 1987-08-28 | Pf Medicament | Procede de preparation de vincristine |
| WO2001024763A2 (en) | 1999-10-01 | 2001-04-12 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| JP2003513756A (ja) * | 1999-11-12 | 2003-04-15 | アンジオテック ファーマシューティカルズ，インコーポレイテッド | 放射性治療と細胞周期インヒビターとの組合せの組成物 |
| ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| CN115540503B (zh) * | 2022-10-28 | 2024-04-23 | 广州白云山汉方现代药业有限公司 | 一种硫酸长春新碱三元溶剂体系下的程序性干燥方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3354163A (en) * | 1966-12-15 | 1967-11-21 | Eli Lillty And Company | Nu-desmethylvinblastine |
| GB1382460A (en) * | 1972-12-04 | 1975-01-29 | Richter Gedeon Vegyeszet | Vincristine separation process |
| US3899493A (en) * | 1972-12-29 | 1975-08-12 | Richter Gedeon Vegyeszet | Chromic acid oxidation of vinblastine sulfate to form vincristine |
| US4110330A (en) * | 1977-05-27 | 1978-08-29 | Eli Lilly And Company | 5'-Acetonylvincristine and related compounds |
| US4195022A (en) * | 1978-03-27 | 1980-03-25 | Eli Lilly And Company | 4-Desacetoxy-4α-hydroxyvinblastine and related compounds |
| HU178706B (en) * | 1979-04-23 | 1982-06-28 | Richter Gedeon Vegyeszet | Process for preparing bis-indole alkaloids and acid addition salts thereof |
| HU183385B (en) * | 1980-04-02 | 1984-04-28 | Lilly Co Eli | Process for preparing vinca dimer derivatives |
| JPS57188596A (en) * | 1981-05-12 | 1982-11-19 | Lilly Co Eli | Manufacture of vinca dimer |
-
1981
- 1981-11-16 US US06/321,662 patent/US4375432A/en not_active Expired - Lifetime
-
1982
- 1982-11-10 IL IL67219A patent/IL67219A/xx not_active IP Right Cessation
- 1982-11-11 GR GR69790A patent/GR77791B/el unknown
- 1982-11-12 DK DK504882A patent/DK161254C/da not_active IP Right Cessation
- 1982-11-12 JP JP57199652A patent/JPS5890591A/ja active Granted
- 1982-11-12 CA CA000415468A patent/CA1180328A/en not_active Expired
- 1982-11-15 GB GB08232561A patent/GB2109378B/en not_active Expired
- 1982-11-15 EP EP82306057A patent/EP0079785B1/en not_active Expired
- 1982-11-15 DE DE8282306057T patent/DE3277200D1/de not_active Expired
- 1982-11-15 IE IE2714/82A patent/IE54172B1/en not_active IP Right Cessation
- 1982-11-16 HU HU823674A patent/HU189620B/hu unknown
- 1982-11-16 KR KR8205165A patent/KR860000488B1/ko active
Also Published As
| Publication number | Publication date |
|---|---|
| GR77791B (el) | 1984-09-25 |
| DK161254B (da) | 1991-06-17 |
| DE3277200D1 (en) | 1987-10-15 |
| JPS5890591A (ja) | 1983-05-30 |
| CA1180328A (en) | 1985-01-02 |
| DK504882A (da) | 1983-05-17 |
| KR840002399A (ko) | 1984-07-02 |
| EP0079785A2 (en) | 1983-05-25 |
| IE54172B1 (en) | 1989-07-05 |
| EP0079785B1 (en) | 1987-09-09 |
| EP0079785A3 (en) | 1984-03-28 |
| US4375432A (en) | 1983-03-01 |
| JPH049792B2 (el) | 1992-02-21 |
| GB2109378A (en) | 1983-06-02 |
| IE822714L (en) | 1983-05-16 |
| KR860000488B1 (ko) | 1986-04-30 |
| HU189620B (en) | 1986-07-28 |
| GB2109378B (en) | 1985-07-17 |
| IL67219A (en) | 1985-09-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK112582A (da) | Fremgangsmaade til fremstilling af triazolonderivater | |
| DK66582A (da) | Fremgangsmaade til fremstilling af carbostyrilderivater | |
| DK354482A (da) | Fremgangsmaade til fremstilling af substituerede pyridazinderivater | |
| DK491582A (da) | Fremgangsmaade til fremstilling af morphinanderivater | |
| DK352082A (da) | Fremgangsmaade til fremstilling af ergopeptinderivater | |
| DK399282A (da) | Fremgangsmaade til fremstilling af cephalosporinderivater | |
| DK324182A (da) | Fremgangsmaade til fremstilling af ergolinderivater | |
| DK150070C (da) | Analogifremgangsmaade til fremstilling af n-dihydrothiazolyl-3-quinolincarboxamidderivater | |
| DK416082A (da) | Fremgangsmaade til fremstilling af aminopropanolderivater af 2-hydroxy-beta-phenylpropiophenoner | |
| DK353781A (da) | Fremgangsmaade til fremstilling af insulinderivater | |
| DK494882A (da) | Fremgangsmaade til fremstilling af ergolinderivater | |
| DK312082A (da) | Fremgangsmaade til fremstilling af benzothiazolsulfonamidderivater | |
| DK160555C (da) | Fremgangsmaade til fremstilling af eburnamoninderivater | |
| DK462983A (da) | Fremgangsmaade til kontinuerlig fremstilling af azoforbindelser | |
| DK116982A (da) | Fremgangsmaade til fremstilling af alkylendioxybenzenderivater | |
| DK156722C (da) | Analogifremgangsmaade til fremstilling af 2-piperazinopyrimidinderivater | |
| DK161254C (da) | Fremgangsmaade til fremstilling af 1-formyl-derivater af dimere indol-dihydroindol-forbindelser | |
| DK507282A (da) | Fremgangsmaade til fremstilling af azinorifamycin forbindelser | |
| DK375882A (da) | Fremgangsmaade til fremstilling af benzisoxazolderivater | |
| DK480482A (da) | Fremgangsmaade til syntese af alfa-chlormethylchlorformiat | |
| DK70482A (da) | Fremgangsmaade til fremstilling af diazolderivater | |
| DK396482A (da) | Fremgangsmaade til fremstilling af cephalosporinderivater | |
| DK245682A (da) | Fremgangsmaade til fremstilling af basisk substituerede phenylacetonitril-forbindelser | |
| DK553882A (da) | Fremgangsmaade til fremstilling af benzo-anellerede heterocycliske forbindelser | |
| DK289382A (da) | Fremgangsmaade til fremstilling af hidtil ukendte derivater af benzoylphenylpiperidin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired |