DK1608349T3 - Oralt tilförselssystem omfattende et antibakterielt og et antiinflammatorisk middel - Google Patents

Oralt tilförselssystem omfattende et antibakterielt og et antiinflammatorisk middel

Info

Publication number
DK1608349T3
DK1608349T3 DK04757724T DK04757724T DK1608349T3 DK 1608349 T3 DK1608349 T3 DK 1608349T3 DK 04757724 T DK04757724 T DK 04757724T DK 04757724 T DK04757724 T DK 04757724T DK 1608349 T3 DK1608349 T3 DK 1608349T3
Authority
DK
Denmark
Prior art keywords
agent
antibacterial
delivery system
oral delivery
inflammatory agent
Prior art date
Application number
DK04757724T
Other languages
English (en)
Inventor
Adel Penhasi
Albert Reuveni
Dan Oren
Original Assignee
Dexcel Pharma Technologies Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dexcel Pharma Technologies Ltd filed Critical Dexcel Pharma Technologies Ltd
Application granted granted Critical
Publication of DK1608349T3 publication Critical patent/DK1608349T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063Periodont
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Physiology (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK04757724T 2003-03-19 2004-03-17 Oralt tilförselssystem omfattende et antibakterielt og et antiinflammatorisk middel DK1608349T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/391,196 US20040185009A1 (en) 2003-03-19 2003-03-19 Composition and device for treating periodontal diseases
PCT/IL2004/000252 WO2004084873A1 (en) 2003-03-19 2004-03-17 Oral delivery system comprising an antibacterial and an anti-inflammatory agent

Publications (1)

Publication Number Publication Date
DK1608349T3 true DK1608349T3 (da) 2008-02-18

Family

ID=32987657

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04757724T DK1608349T3 (da) 2003-03-19 2004-03-17 Oralt tilförselssystem omfattende et antibakterielt og et antiinflammatorisk middel

Country Status (10)

Country Link
US (1) US20040185009A1 (da)
EP (1) EP1608349B1 (da)
AT (1) ATE375789T1 (da)
CA (1) CA2519038A1 (da)
DE (1) DE602004009552T2 (da)
DK (1) DK1608349T3 (da)
ES (1) ES2298787T3 (da)
PL (1) PL1608349T3 (da)
PT (1) PT1608349E (da)
WO (1) WO2004084873A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7972137B2 (en) * 2003-06-30 2011-07-05 Rosen Gerald M Anti-microbial dental formulations for the prevention and treatment of oral mucosal disease
FR2896057A1 (fr) * 2006-01-12 2007-07-13 St Microelectronics Sa Procede et dispositif de generation d'un nombre aleatoire dans un peripherique usb
US20080241795A1 (en) * 2007-03-26 2008-10-02 Block James C Prevention and treatment of alveolar osteitis
CN101686964A (zh) * 2007-05-22 2010-03-31 威斯康星旧生研究基金会 基因组维护接口的抗细菌药物靶向
US20100040628A1 (en) * 2008-08-12 2010-02-18 OsteoGeneX, Inc Indoprofen derivatives for promoting bone growth
US20100098746A1 (en) * 2008-10-20 2010-04-22 Warsaw Orthopedic, Inc. Compositions and methods for treating periodontal disease comprising clonidine, sulindac and/or fluocinolone
AU2010267528A1 (en) 2009-07-01 2012-02-02 Dexcel Pharma Technologies Ltd. Local therapeutic release device
JP5653602B2 (ja) * 2009-09-02 2015-01-14 東洋精糖株式会社 高吸収性薬剤組成物およびその製造方法
US8865198B2 (en) 2010-10-25 2014-10-21 Dexcel Pharma Technologies Ltd. Method for treating a periodontal disease
DE102012001979A1 (de) 2012-02-02 2013-08-08 Voco Gmbh Härtbares Gemisch umfassend Weichmacher mit einem polyalicyclischen Strukturelement zur Anwendung bei der Herstellung dentaler Werkstoffe
DE102012001978A1 (de) 2012-02-02 2013-08-08 Voco Gmbh Dentale Kompositmaterialien enthaltend tricyclische Weichmacher
WO2015140802A2 (en) 2014-03-20 2015-09-24 Technion Research & Development Foundation Limited Delivery system comprising a proteolytic enzyme or effector thereof for use in a method for oral treatment and uses thereof
RU2652349C1 (ru) * 2017-03-13 2018-04-25 Федеральное государственное бюджетное образовательное учреждение дополнительного профессионального образования "Российская медицинская академия непрерывного профессионального образования" Министерства здравоохранения Российской Федерации (ФГБОУ ДПО РМАНПО Минздрава России) Способ местного лечения воспалительных заболеваний пародонта
CN107303218A (zh) * 2017-04-28 2017-10-31 上海旷视医疗科技有限公司 角/巩膜交联技术的安全控制及效能优化系统
IT201800003872A1 (it) * 2018-03-22 2019-09-22 Dtech Soc A Responsabilita Limitata Prodotto per il trattamento terapeutico per la prevenzione e cura di patologie del cavo orale, dei denti e degli impianti dentali
DE102019000322A1 (de) 2019-01-14 2020-07-16 Beuth Hochschule Für Technik Berlin Polymerzusammensetzung mit antiseptischen Eigenschaften und Verfahren zur Herstellung
DE102019000321A1 (de) 2019-01-14 2020-07-16 Beuth Hochschule Für Technik Berlin Orale Polymerzusammensetzung mit verzögerter Freisetzung
DE102019122174A1 (de) 2019-08-19 2021-02-25 Voco Gmbh Dentale polymerisierbare Zusammensetzung auf der Basis kondensierter Silane
DE102020007979A1 (de) 2020-12-29 2022-06-30 Charité Universitätsmedizin Institut für Mikrobiologie und Infektionsimmunologie Zusammensetzung zur Behandlung von lnfektionen mit Coronaviren

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59222406A (ja) * 1983-06-01 1984-12-14 Teijin Ltd 歯周疾患治療用製剤及びその製造法
US4892736A (en) * 1983-10-07 1990-01-09 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
US4764377A (en) * 1983-10-07 1988-08-16 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
US5002769A (en) * 1987-03-13 1991-03-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions for the sustained-release of chlorhexidine
US5160737A (en) * 1988-05-03 1992-11-03 Perio Products Ltd. Liquid polymer composition, and method of use
US5702716A (en) * 1988-10-03 1997-12-30 Atrix Laboratories, Inc. Polymeric compositions useful as controlled release implants
US5324520A (en) * 1988-12-19 1994-06-28 Vipont Pharmaceutical, Inc. Intragingival delivery systems for treatment of periodontal disease
US5236355A (en) * 1988-12-22 1993-08-17 American Cyanamid Company Apparatus for the treatment of periodontal disease
EP0374531B1 (en) * 1988-12-22 1994-05-04 American Cyanamid Company Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, composition of matter therefor and apparatus for the administration thereof
US5190981A (en) * 1989-08-17 1993-03-02 Sepracor Inc. Formulation containing S(+) enantiomer of flurbiprofen or ketoprofen and method of use for oral administration for prevention and treatment of bone loss associated with periodontal disease
US5308839A (en) * 1989-12-04 1994-05-03 The Research Foundation Of State University Of New York Composition comprising non-steroidal anti-inflammatory agent tenidap and effectively non-antibacterial tetracycline
US5242910A (en) * 1992-10-13 1993-09-07 The Procter & Gamble Company Sustained release compositions for treating periodontal disease
US5660854A (en) * 1994-11-28 1997-08-26 Haynes; Duncan H Drug releasing surgical implant or dressing material
US5902110A (en) * 1995-12-18 1999-05-11 The Block Drug Company Bone regeneration
US5800832A (en) * 1996-10-18 1998-09-01 Virotex Corporation Bioerodable film for delivery of pharmaceutical compounds to mucosal surfaces
CA2296654A1 (en) * 1997-07-23 1999-02-04 Perio Products Ltd. Tannic acid-polymer compositions for controlled release of pharmaceutical agents, particularly in the oral cavity
US6197331B1 (en) * 1997-07-24 2001-03-06 Perio Products Ltd. Pharmaceutical oral patch for controlled release of pharmaceutical agents in the oral cavity
US5980925A (en) * 1997-12-30 1999-11-09 Ethicon, Inc. High glycerin containing anti-microbial cleansers
RU2214244C9 (ru) * 1998-03-26 2020-07-29 Астеллас Фарма Инк. Препараты с замедленным высвобождением
US20010049363A1 (en) * 1998-05-08 2001-12-06 Warner-Lambert Company Oral composition containing NSAIDs and essential oils
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Also Published As

Publication number Publication date
WO2004084873A1 (en) 2004-10-07
EP1608349B1 (en) 2007-10-17
EP1608349A1 (en) 2005-12-28
ES2298787T3 (es) 2008-05-16
DE602004009552T2 (de) 2008-07-24
CA2519038A1 (en) 2004-10-07
US20040185009A1 (en) 2004-09-23
PT1608349E (pt) 2008-01-25
DE602004009552D1 (de) 2007-11-29
PL1608349T3 (pl) 2008-07-31
ATE375789T1 (de) 2007-11-15

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