DK160082A - Fremgangsmaade til fremstilling af 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)-butyl)-8-azaapiro(4,5)-dekan-7,9-dion - Google Patents

Fremgangsmaade til fremstilling af 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)-butyl)-8-azaapiro(4,5)-dekan-7,9-dion Download PDF

Info

Publication number
DK160082A
DK160082A DK160082A DK160082A DK160082A DK 160082 A DK160082 A DK 160082A DK 160082 A DK160082 A DK 160082A DK 160082 A DK160082 A DK 160082A DK 160082 A DK160082 A DK 160082A
Authority
DK
Denmark
Prior art keywords
formula
image
compound
piperazinyl
pyrimidinyl
Prior art date
Application number
DK160082A
Other languages
English (en)
Other versions
DK152730B (da
DK152730C (da
Inventor
P J Kairisalo
E J Honkanen
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of DK160082A publication Critical patent/DK160082A/da
Publication of DK152730B publication Critical patent/DK152730B/da
Application granted granted Critical
Publication of DK152730C publication Critical patent/DK152730C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK160082A 1981-04-09 1982-04-07 Fremgangsmaade til fremstilling af 8-ae4-oe4-(2-pyrimidinyl)-1-piperazinylaa-butylaa-8-azaspiro(4,5)-dekan-7,9-dion DK152730C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI811108 1981-04-09
FI811108 1981-04-09

Publications (3)

Publication Number Publication Date
DK160082A true DK160082A (da) 1982-10-10
DK152730B DK152730B (da) 1988-05-02
DK152730C DK152730C (da) 1988-10-03

Family

ID=8514296

Family Applications (1)

Application Number Title Priority Date Filing Date
DK160082A DK152730C (da) 1981-04-09 1982-04-07 Fremgangsmaade til fremstilling af 8-ae4-oe4-(2-pyrimidinyl)-1-piperazinylaa-butylaa-8-azaspiro(4,5)-dekan-7,9-dion

Country Status (3)

Country Link
DK (1) DK152730C (da)
NO (1) NO821086L (da)
SE (1) SE449224B (da)

Also Published As

Publication number Publication date
SE8202132L (sv) 1982-10-10
SE449224B (sv) 1987-04-13
NO821086L (no) 1982-10-11
DK152730B (da) 1988-05-02
DK152730C (da) 1988-10-03

Similar Documents

Publication Publication Date Title
JPS5817454B2 (ja) アルキル化ヒドロキシルアミン及びその製法
JPS5645464A (en) Substituted oxiranecarboxylic acid* drug containing it* its manufacture and alphaamethylenecarboxylic acid and drug containing alphaamethylenecarboxylic acid
DE3043252A1 (de) Cyclische acetale von n-acylglutaminsaeure- (gamma) -semialdehyden, verfahren zu deren herstellung und ihre verwendung
DE3424685A1 (de) Neue substituierte phenylpiperazinyl-propanole, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
DE69132082T2 (de) Pyridin-Derivate, Verfahren zu deren Herstellung und Anwendung
EP0008645A1 (de) Alkoxyphenylpyrrolidone, Verfahren zu ihrer Herstellung und Arzneimittel auf Basis dieser Verbindungen
DK160082A (da) Fremgangsmaade til fremstilling af 8-(4-(4-(2-pyrimidinyl)-1-piperazinyl)-butyl)-8-azaapiro(4,5)-dekan-7,9-dion
ATE38515T1 (de) Spiro-2-aza-alkan-3-carbonitrile, verfahren zu ihrer herstellung und ihre verwendung.
SU795469A3 (ru) Способ получени производныхуРАцилА
US4292431A (en) Process for the production of hydroxymethylimidazoles
SE8005127L (sv) Sett att framstella 15-hydroxiimino-e-homoeburnanderivat
US2987546A (en) Acyl-and amino-substituted phenol ethers
ES8500742A1 (es) Procedimiento para la preparacion de derivados de acido fenilacetico
ES8307236A1 (es) Un procedimiento para la preparacion de ranitidina.
JPS54148786A (en) Preparation of 1,3-dimethyl-4-(2,4-dichlorobenzoyl)-5- hydroxypyrazole
DE2962281D1 (en) Substituted 2-phenylamino-3,4,5,6-tetrahydropyrimidines, their acid addition salts, medicines containing them and process for their preparation
JPS57142929A (en) Forming method of dipentaerythritol or ditrimethylolalkane as by-product at given ratio
JPS554349A (en) Preparation of creatine
JPS5594374A (en) Preparation of orotic acid
ATE5583T1 (de) 4-methyl-3-formylpentensaeurealkylester, deren herstellungsverfahren, deren verwendung zur herstellung der 4-methyl-3-formyl-3-pentensaeure und die zwischenprodukte.
US2945043A (en) Diloweralkl
KR860008171A (ko) 4-아미노알킬리덴-치환 3-알킬-5(4h)이속사졸론의 제조방법
Ruskin et al. A Synthesis of 5-Ethyl-5-(5', 5'-phenylhydantoin) Barbituric Acid
JPS55143960A (en) Novel acetal compound and its preparation
Chattaway et al. The condensation of bromal with urea

Legal Events

Date Code Title Description
PBP Patent lapsed
PBP Patent lapsed