DK159785C - Fremgangsmaade til fremstilling af et krystallinsk hemi-syresalt af et cephalosporinderivat - Google Patents

Fremgangsmaade til fremstilling af et krystallinsk hemi-syresalt af et cephalosporinderivat

Info

Publication number
DK159785C
DK159785C DK524579A DK524579A DK159785C DK 159785 C DK159785 C DK 159785C DK 524579 A DK524579 A DK 524579A DK 524579 A DK524579 A DK 524579A DK 159785 C DK159785 C DK 159785C
Authority
DK
Denmark
Prior art keywords
preparing
procedure
acid salt
crystalline hemi
cephalosporine derivative
Prior art date
Application number
DK524579A
Other languages
Danish (da)
English (en)
Other versions
DK159785B (da
DK524579A (da
Inventor
Hideaki Natsugari
Iwao Mikami
Michihiko Ochiai
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK524579A publication Critical patent/DK524579A/da
Publication of DK159785B publication Critical patent/DK159785B/da
Application granted granted Critical
Publication of DK159785C publication Critical patent/DK159785C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK524579A 1978-12-11 1979-12-10 Fremgangsmaade til fremstilling af et krystallinsk hemi-syresalt af et cephalosporinderivat DK159785C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP15337778 1978-12-11
JP15337778A JPS5579393A (en) 1978-12-11 1978-12-11 Cephalosporin derivative and its preparation

Publications (3)

Publication Number Publication Date
DK524579A DK524579A (da) 1980-06-12
DK159785B DK159785B (da) 1990-12-03
DK159785C true DK159785C (da) 1991-04-22

Family

ID=15561123

Family Applications (1)

Application Number Title Priority Date Filing Date
DK524579A DK159785C (da) 1978-12-11 1979-12-10 Fremgangsmaade til fremstilling af et krystallinsk hemi-syresalt af et cephalosporinderivat

Country Status (18)

Country Link
US (1) US4298607A (sv)
JP (1) JPS5579393A (sv)
BE (1) BE880518A (sv)
CA (1) CA1128499A (sv)
CH (1) CH646437A5 (sv)
DE (1) DE2949485A1 (sv)
DK (1) DK159785C (sv)
ES (1) ES8100299A1 (sv)
FR (1) FR2444042A1 (sv)
GB (1) GB2036746B (sv)
GR (1) GR74078B (sv)
HK (1) HK9486A (sv)
IT (1) IT1126514B (sv)
MY (1) MY8500456A (sv)
NL (1) NL190487C (sv)
NO (1) NO158219C (sv)
SE (1) SE447117B (sv)
SG (1) SG93185G (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR78221B (sv) * 1980-02-01 1984-09-26 Ciba Geigy Ag
US4400503A (en) * 1981-10-30 1983-08-23 Eli Lilly And Company Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid
US4594417A (en) * 1981-10-30 1986-06-10 Eli Lilly Company Crystalline antibiotic salt
US4902683A (en) * 1984-10-25 1990-02-20 The Upjohn Company Crystalline cephalosporin hydrohalide salts
EP0638573A1 (en) * 1993-08-10 1995-02-15 Lucky Ltd. Crystalline hydrates of cephalosporin and process for preparation thereof
EP1606293B1 (en) * 2003-03-27 2009-08-19 Basilea Pharmaceutica AG Cephalosporin in crystalline form

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
JPS603314B2 (ja) * 1976-08-31 1985-01-26 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
NL190487C (nl) 1994-03-16
DE2949485A1 (de) 1980-06-19
CH646437A5 (de) 1984-11-30
JPS636552B2 (sv) 1988-02-10
SE447117B (sv) 1986-10-27
FR2444042B1 (sv) 1983-06-24
DK159785B (da) 1990-12-03
SG93185G (en) 1987-03-27
NO158219C (no) 1988-08-03
NO793989L (no) 1980-06-12
HK9486A (en) 1986-02-14
GB2036746A (en) 1980-07-02
DK524579A (da) 1980-06-12
JPS5579393A (en) 1980-06-14
IT1126514B (it) 1986-05-21
GB2036746B (en) 1983-02-09
ES486680A0 (es) 1980-11-01
NO158219B (no) 1988-04-25
BE880518A (fr) 1980-06-10
FR2444042A1 (fr) 1980-07-11
GR74078B (sv) 1984-06-06
DE2949485C2 (sv) 1989-06-08
NL190487B (nl) 1993-10-18
NL7908869A (nl) 1980-06-13
MY8500456A (en) 1985-12-31
SE7909998L (sv) 1980-06-12
IT7927924A0 (it) 1979-12-07
US4298607A (en) 1981-11-03
ES8100299A1 (es) 1980-11-01
CA1128499A (en) 1982-07-27

Similar Documents

Publication Publication Date Title
DK425579A (da) Fremgangsmaade til fremstilling af heterocycliske forbindelser
DK152213C (da) Fremgangsmaade til fremstilling af en krystallinsk form af natriumsaltet af et oximderivat af 7-aminothiazolylacetamidocephalosporansyre
DK388079A (da) R fremgangsmaade til fremstilling af heterocycliske forbindelse
SE426069B (sv) Forfarande for framstellning av ett kristallint cefalosporinderivat
DK541782A (da) Fremgangsmaade til fremstilling af et salt af 2-(2-fluor-4-bifenyl)-propionsyre
DK7679A (da) Fremgangsmaade til fremstilling af et prostaglandinholdigt praeparat
DK159785C (da) Fremgangsmaade til fremstilling af et krystallinsk hemi-syresalt af et cephalosporinderivat
NO790994L (no) Fremgangsmaate for fremstilling av et soyasapogenolderivat
SE438337B (sv) Forfarande for framstellning av 2-(metyl)-7-substituerade 3-cefem-4-karboxylsyraforeningar
DK493780A (da) Fremgangsmaade til fremstilling af et nicotinamidderivat
DK159153C (da) Analogifremgangsmaade til fremstilling af penicillinforbindelser
ES486028A0 (es) Un procedimiento para preparar derivados de indol policiclicos
DK480982A (da) Fremgangsmaade til fremstilling af et krystallinsk hydrochloridsalt af et cephalosporinderivat
DK231979A (da) Fremgangsmaade til fremstilling af et krystallinsk cephalosporin-derivat
DK550276A (da) Fremgangsmade til fremstilling af en krystalmodifikation af et natriumsalt
DK225179A (da) Fremgangsmaade til fremstilling af cephalosporinderivater
DK172880A (da) Fremgangsmaade til fremstilling af en krystallinsk d-isomer af en oxa-lactamforbindelse
DK12879A (da) R fremgangsmaade til fremstilling af ergopeptidalkaloidderivate
DK177980A (da) Fremgangsmaade til fremstilling af et krystallinsk d-diammoniumsalt af en oxa-beta-lactamforbindelse
DK217079A (da) Fremgangsmaade til fremstilling af cephalosporinforbindelser
DK331579A (da) R fremgangsmaade til fremstilling af 2-aminobenzophenonderivate
DK378979A (da) Fremgangsmaade til fremstilling af naphthopyranforbindelser
DK172679A (da) Fremgangmmaade til fremstilling af fenylaeterforbindelser
DK2884D0 (da) Fremgangsmade til fremstilling af et cephalosporinderivat
SE7800378L (sv) Forfarande for framstellning av ett nytt cefalosporinderivat