DK159100C - Fremgangsmaade til fremstilling af en flydende viral vaccine indeholdende en stabilisator og stabilisator, der kan benyttes i en saadan fremgangsmaade - Google Patents

Fremgangsmaade til fremstilling af en flydende viral vaccine indeholdende en stabilisator og stabilisator, der kan benyttes i en saadan fremgangsmaade

Info

Publication number
DK159100C
DK159100C DK455880A DK455880A DK159100C DK 159100 C DK159100 C DK 159100C DK 455880 A DK455880 A DK 455880A DK 455880 A DK455880 A DK 455880A DK 159100 C DK159100 C DK 159100C
Authority
DK
Denmark
Prior art keywords
stabilizer
procedure
preparing
vaccine containing
viral vaccine
Prior art date
Application number
DK455880A
Other languages
Danish (da)
English (en)
Other versions
DK455880A (da
DK159100B (da
Inventor
William J Mcaleer
Henry Z Markus
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK455880A publication Critical patent/DK455880A/da
Publication of DK159100B publication Critical patent/DK159100B/da
Application granted granted Critical
Publication of DK159100C publication Critical patent/DK159100C/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18411Morbillivirus, e.g. Measles virus, canine distemper
    • C12N2760/18434Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
DK455880A 1979-10-29 1980-10-28 Fremgangsmaade til fremstilling af en flydende viral vaccine indeholdende en stabilisator og stabilisator, der kan benyttes i en saadan fremgangsmaade DK159100C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US8906879A 1979-10-29 1979-10-29
US8906879 1979-10-29
US11870380A 1980-02-05 1980-02-05
US11870380 1980-02-05

Publications (3)

Publication Number Publication Date
DK455880A DK455880A (da) 1981-04-30
DK159100B DK159100B (da) 1990-09-03
DK159100C true DK159100C (da) 1991-02-11

Family

ID=26780218

Family Applications (1)

Application Number Title Priority Date Filing Date
DK455880A DK159100C (da) 1979-10-29 1980-10-28 Fremgangsmaade til fremstilling af en flydende viral vaccine indeholdende en stabilisator og stabilisator, der kan benyttes i en saadan fremgangsmaade

Country Status (7)

Country Link
EP (1) EP0028563B1 (de)
DE (1) DE3067376D1 (de)
DK (1) DK159100C (de)
ES (1) ES496358A0 (de)
GR (1) GR70319B (de)
IE (1) IE50276B1 (de)
PT (1) PT71926B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5716823A (en) * 1980-07-03 1982-01-28 Green Cross Corp:The Live mumps vaccine pharmaceutical and stabilizing method
US4554101A (en) * 1981-01-09 1985-11-19 New York Blood Center, Inc. Identification and preparation of epitopes on antigens and allergens on the basis of hydrophilicity
MX7528E (es) * 1981-01-09 1989-08-02 New York Blood Center Inc Procedimiento para la preparacion de una vacuna sintetica
FR2505657A1 (fr) * 1981-05-13 1982-11-19 Pasteur Institut Perfectionnements apportes aux agents de stabilisation de virus vivants pour la preparation de vaccins, et vaccins stabilises contenant lesdits agents de stabilisation
FR2532548B1 (fr) * 1982-09-03 1985-11-08 Pasteur Institut Nouveau procede de production de vaccins presentant un titre eleve de virus et vaccins tres purifies, a titre eleve de virus, ainsi obtenus
DK331087A (da) * 1986-06-30 1987-12-31 Smith Kline Rit Stabilisator for levende vaccine
JPS63307827A (ja) * 1987-06-08 1988-12-15 Kitasato Inst:The 安定化された生ウイルスワクチンおよびその製造法
AU1633092A (en) * 1991-05-17 1992-11-19 Merck & Co., Inc. Non-stinging vaccine composition
CA2075521C (en) * 1992-05-05 1995-11-28 Kuniaki Koyama Stabilized live vaccine
US6403098B1 (en) * 1996-09-26 2002-06-11 Merck & Co., Inc. Rotavirus vaccine formulations
US6051238A (en) * 1996-12-20 2000-04-18 Merck & Co., Inc. Stabilizers for lyophilized mumps vaccines
EP0946193A1 (de) * 1996-12-20 1999-10-06 Merck & Co., Inc. Stabilisatoren fpr lyophilisierte impfstoffe
GB9808922D0 (en) * 1998-04-24 1998-06-24 Cantab Pharmaceuticals Res Ltd Virus preparations
US20040022800A1 (en) * 2000-07-31 2004-02-05 Mark Parrington Respiratory syncytial virus vaccine
WO2006052813A2 (en) 2004-11-05 2006-05-18 Wellstat Biologics Corporation Stable and filterable enveloped virus formulations
US20060141483A1 (en) * 2004-12-23 2006-06-29 Calton Gary J Stabilization of viral compositions
DK1973406T3 (da) 2005-12-28 2014-06-23 Advanced Bionutrition Corp Fremføringsmiddel til probiotiske bakerier omfattende en tør blanding af polysaccharider, saccharider, polyoler i glasform
JP5285617B2 (ja) 2006-12-18 2013-09-11 アドバンスド バイオニュートリション コーポレーション 生きたプロバイオティクスを含む乾燥食物製品
CA2756883C (en) 2009-03-27 2018-01-09 Advanced Bionutrition Corp. Microparticulated vaccines for the oral or nasal vaccination and boostering of animals including fish
RU2567668C2 (ru) 2009-05-26 2015-11-10 Эдванст Бионутришн Корпорейшн Стабильная сухая порошкообразная композиция, содержащая биологически активные микроорганизмы и/или биоактивные материалы, и способ ее изготовления
NZ601017A (en) 2010-01-28 2014-07-25 Advanced Bionutrition Corp Dry glassy composition comprising a bioactive material
US9504750B2 (en) 2010-01-28 2016-11-29 Advanced Bionutrition Corporation Stabilizing composition for biological materials
RS57588B1 (sr) 2010-08-13 2018-11-30 Advanced Bionutrition Corp Supstanca za stabilizaciju bioloških materijala za suvo skladištenje
EP3246400B1 (de) 2012-01-09 2019-10-23 Sanofi Pasteur Biologics, LLC Aufreinigung von herpesvirus
CA2873775C (en) 2012-05-21 2021-04-20 Sanofi Pasteur Limited Herpesvirus compositions and related methods
US9314519B2 (en) 2012-08-21 2016-04-19 Intervet Inc. Liquid stable virus vaccines
US9480739B2 (en) 2013-03-15 2016-11-01 Intervet Inc. Bovine virus vaccines that are liquid stable
US9393298B2 (en) 2013-03-15 2016-07-19 Intervet Inc. Liquid stable bovine virus vaccines
AR097762A1 (es) 2013-09-27 2016-04-13 Intervet Int Bv Formulaciones secas de vacunas que son estables a temperatura ambiente
AR099470A1 (es) * 2014-02-17 2016-07-27 Intervet Int Bv Vacunas de virus de aves de corral líquidas
TWI670085B (zh) * 2014-02-19 2019-09-01 荷蘭商英特威國際公司 液體穩定之豬病毒疫苗
WO2017019273A1 (en) 2015-07-29 2017-02-02 Advanced Bionutrition Corporation Stable dry probiotic compositions for special dietary uses
MA56118A (fr) 2019-06-10 2022-04-13 Boehringer Ingelheim Animal Health Usa Inc Vaccin vivant liquide stabilisé

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE641705A (de) * 1963-12-23 1964-06-23
BE665076A (de) * 1963-12-23 1965-12-08
FR2076787A5 (en) * 1970-01-28 1971-10-15 Merieux Inst Lyophilisation stabiliser - for viruses contg potassium phosphate lactose and albumin
NL7115348A (de) * 1970-11-25 1972-05-29
US3783098A (en) * 1971-08-10 1974-01-01 Cornell Res Foundation Inc Highly potent,viable and stable cellfree virus preparations from cells infected with cell-associated viruses and method for obtaining the same
IL44143A0 (en) * 1973-02-07 1974-05-16 Wellcome Found Method of inactivating viruses and vaccines prepared thereby
US3915794A (en) * 1973-02-09 1975-10-28 Rit Rech Ind Therapeut Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them
US4147772A (en) * 1976-02-03 1979-04-03 Merck & Co., Inc. Vaccine stabilizer
DE2816349A1 (de) * 1978-04-14 1979-10-25 Merck & Co Inc Vaccinstabilisator
FR2424031A1 (fr) * 1978-04-24 1979-11-23 Merck & Co Inc Stabilisateur de vaccin
BE866330A (fr) * 1978-04-25 1978-10-25 Merck & Co Inc Procede de fabrication d'un agent de stabilisation de vaccin
LU79529A1 (fr) * 1978-04-26 1978-11-28 Merck & Co Inc Procede de fabrication d'un agent de stabilisation de vaccin

Also Published As

Publication number Publication date
PT71926A (en) 1980-11-01
DE3067376D1 (en) 1984-05-10
DK455880A (da) 1981-04-30
GR70319B (de) 1982-09-10
IE50276B1 (en) 1986-03-19
IE802225L (en) 1981-04-29
DK159100B (da) 1990-09-03
EP0028563A1 (de) 1981-05-13
ES8202584A1 (es) 1982-02-01
EP0028563B1 (de) 1984-04-04
ES496358A0 (es) 1982-02-01
PT71926B (en) 1982-03-31

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