DK1585470T3 - Transdermal afgivelse af fentanyl - Google Patents

Transdermal afgivelse af fentanyl

Info

Publication number
DK1585470T3
DK1585470T3 DK03781469.6T DK03781469T DK1585470T3 DK 1585470 T3 DK1585470 T3 DK 1585470T3 DK 03781469 T DK03781469 T DK 03781469T DK 1585470 T3 DK1585470 T3 DK 1585470T3
Authority
DK
Denmark
Prior art keywords
fentanyl
transdermal delivery
formulations
suspended
matrix
Prior art date
Application number
DK03781469.6T
Other languages
English (en)
Inventor
Kenneth J Ii Miller
Sharad K Govil
Kuljit Singh Bhatia
Original Assignee
Mylan Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mylan Pharmaceuticals Inc filed Critical Mylan Pharmaceuticals Inc
Application granted granted Critical
Publication of DK1585470T3 publication Critical patent/DK1585470T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
DK03781469.6T 2002-10-30 2003-10-29 Transdermal afgivelse af fentanyl DK1585470T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/283,355 US20040086551A1 (en) 2002-10-30 2002-10-30 Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
PCT/US2003/034403 WO2004041324A2 (en) 2002-10-30 2003-10-29 Transdermal delivery of fentanyl

Publications (1)

Publication Number Publication Date
DK1585470T3 true DK1585470T3 (da) 2011-06-27

Family

ID=32174649

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03781469.6T DK1585470T3 (da) 2002-10-30 2003-10-29 Transdermal afgivelse af fentanyl

Country Status (14)

Country Link
US (8) US20040086551A1 (da)
EP (1) EP1585470B1 (da)
JP (1) JP5069402B2 (da)
AT (1) ATE511393T1 (da)
AU (1) AU2003288977A1 (da)
CA (1) CA2503722C (da)
CY (1) CY1112582T1 (da)
DE (1) DE03781469T1 (da)
DK (1) DK1585470T3 (da)
ES (1) ES2249197T3 (da)
HK (1) HK1075816A1 (da)
PT (1) PT1585470E (da)
SI (1) SI1585470T1 (da)
WO (1) WO2004041324A2 (da)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ528148A (en) * 2001-03-16 2006-02-24 Alza Corp Transdermal patch for administering fentanyl
CA2460352C (en) * 2001-08-17 2013-05-14 Lavipharm Laboratories Inc. Composition and transdermal drug delivery device
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US20040086551A1 (en) * 2002-10-30 2004-05-06 Miller Kenneth J. Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
JP2006517124A (ja) * 2003-02-07 2006-07-20 エルテーエス ローマン テラピー−ジステーメ アーゲー 活性物質の浸透を促進するために熱を用いるのに適した経皮治療システム及びその使用
JP5137286B2 (ja) * 2003-06-10 2013-02-06 帝國製薬株式会社 フェンタニル含有口腔粘膜貼付剤
EP1663179A1 (en) * 2003-07-21 2006-06-07 Noven Pharmaceuticals, Inc. Composition and method for controlling drug delivery from silicone adhesive blends
EP1928881A2 (en) 2005-08-19 2008-06-11 Pharmacofore, Inc. Prodrugs of active agents
EP2402037B8 (en) 2006-05-26 2019-12-04 Signature Therapeutics, Inc. Controlled release of phenolic opioids
WO2008007554A1 (fr) 2006-07-14 2008-01-17 Hisamitsu Pharmaceutical Co., Inc. Préparation d'adhésif
MY154027A (en) * 2007-10-15 2015-04-30 Alza Corp Once-a-day replacement transdermal administration of fentanyl
US8231906B2 (en) * 2008-07-10 2012-07-31 Noven Pharmaceuticals, Inc. Transdermal estrogen device and delivery
DE102011100619A1 (de) 2010-05-05 2012-01-05 Amw Gmbh Transdermales therapeutisches System (TTS) mit einem Gehalt an einem Opiod-Analgetikum
US9205605B2 (en) 2012-04-25 2015-12-08 Textron Innovations Inc. Multi-function detection liner for manufacturing of composites
JP6533520B2 (ja) 2013-06-13 2019-06-19 マイクロダーミクス インコーポレイテッドＭｉｃｒｏｄｅｒｍｉｃｓ Ｉｎｃ． 金属マイクロニードルの作製方法
JP6360614B2 (ja) * 2015-03-02 2018-07-18 久光製薬株式会社 貼付剤
WO2016149077A2 (en) * 2015-03-13 2016-09-22 Amneal Pharmaceuticals Llc Fentanyl transdermal delivery system
CN106714782A (zh) * 2015-06-30 2017-05-24 第三共株式会社 具有滥用遏制性质的药物组合物
US10335406B2 (en) 2015-10-01 2019-07-02 Elysium Therapeutics, Inc. Opioid compositions resistant to overdose and abuse
GB2556817B (en) 2015-10-01 2019-11-06 Elysium Therapeutics Inc Polysubunit opioid prodrugs resistant to overdose and abuse
ES2805342T3 (es) * 2015-10-26 2021-02-11 Hisamitsu Pharmaceutical Co Parche cutáneo adhesivo
US9650338B1 (en) 2016-07-29 2017-05-16 VDM Biochemicals, Inc. Opioid antagonist compounds and methods of making and using
CA3056239C (en) 2017-03-17 2023-09-12 Elysium Therapeutics, Inc. Polysubunit opioid prodrugs resistant to overdose and abuse
US11052054B2 (en) 2017-04-19 2021-07-06 Inep Europe Sarl Method for manufacturing a transdermal device
WO2018194879A1 (en) * 2017-04-19 2018-10-25 Inep Europe Sarl Method for making a transdermal fentanyl patch with even drug crystal distribution
US10391065B2 (en) * 2017-04-19 2019-08-27 Inep Europe Sarl Method for making a transdermal fentanyl patch with even drug crystal distribution
KR20220163495A (ko) * 2017-06-08 2022-12-09 애프리컷 지엠비에이치 피부 관리 및 피부 노화 방지를 위한 활성 물질이 포함된 실리콘 패드
KR102710072B1 (ko) * 2018-08-31 2024-09-24 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
KR20200025883A (ko) * 2018-08-31 2020-03-10 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
US20210393607A1 (en) * 2018-11-09 2021-12-23 Medrx Co., Ltd. Transdermal Patch Containing Fentanyl as Active Ingredient

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US466953A (en) * 1892-01-12 Ammeter
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
US5310559A (en) * 1982-09-01 1994-05-10 Hercon Laboratories Corporation Device for controlled release and delivery to mammalian tissue of pharmacologically active agents incorporating a rate controlling member which comprises an alkylene-alkyl acrylate copolymer
IT1153003B (it) * 1982-11-03 1987-01-14 Grace W R & Co Pellicole laminate per imballaggio e relativi manufatti a migliorata resistenza a trattamenti termici
DE3315272C2 (de) * 1983-04-27 1986-03-27 Lohmann Gmbh & Co Kg, 5450 Neuwied Pharmazeutisches Produkt und Verfahren zu seiner Herstellung
US4588580B2 (en) * 1984-07-23 1999-02-16 Alaz Corp Transdermal administration of fentanyl and device therefor
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4655767A (en) * 1984-10-29 1987-04-07 Dow Corning Corporation Transdermal drug delivery devices with amine-resistant silicone adhesives
US4938759A (en) * 1986-09-02 1990-07-03 Alza Corporation Transdermal delivery device having a rate controlling adhesive
US5006342A (en) * 1986-12-22 1991-04-09 Cygnus Corporation Resilient transdermal drug delivery device
US4906463A (en) * 1986-12-22 1990-03-06 Cygnus Research Corporation Transdermal drug-delivery composition
US5186939A (en) * 1987-04-23 1993-02-16 Cygnus Therapeutic Systems Laminated composite for transdermal administration of fentanyl
US4839174A (en) * 1987-10-05 1989-06-13 Pharmetrix Corporation Novel transdermal nicotine patch
US4943435A (en) * 1987-10-05 1990-07-24 Pharmetrix Corporation Prolonged activity nicotine patch
US5656286A (en) * 1988-03-04 1997-08-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
US5474783A (en) * 1988-03-04 1995-12-12 Noven Pharmaceuticals, Inc. Solubility parameter based drug delivery system and method for altering drug saturation concentration
JP2681365B2 (ja) * 1988-04-11 1997-11-26 日東電工株式会社 経皮吸収性製剤及びその製法
US4882377A (en) * 1988-09-21 1989-11-21 Dow Corning Corporation Low-viscosity pressure-adherent silicone elastomer compositions
US4908213A (en) * 1989-02-21 1990-03-13 Schering Corporation Transdermal delivery of nicotine
DE3910543A1 (de) * 1989-04-01 1990-10-11 Lohmann Therapie Syst Lts Transdermales therapeutisches system mit erhoehtem wirkstofffluss und verfahren zu seiner herstellung
CA2053462A1 (en) * 1990-10-22 1992-04-23 Yoshiaki Yano Sticky composition for medical use
US5232702A (en) * 1991-07-22 1993-08-03 Dow Corning Corporation Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices
US6010715A (en) * 1992-04-01 2000-01-04 Bertek, Inc. Transdermal patch incorporating a polymer film incorporated with an active agent
JP3081858B2 (ja) * 1992-05-12 2000-08-28 日東電工株式会社 貼付剤および貼付製剤
JPH06137725A (ja) 1992-10-28 1994-05-20 Hitachi Ltd 冷凍装置の冷媒漏れ検知方式
US5762952A (en) * 1993-04-27 1998-06-09 Hercon Laboratories Corporation Transdermal delivery of active drugs
US5503844A (en) * 1993-05-18 1996-04-02 Mli Acquisition Corp. Ii Foam laminate transdermal patch
EP0708627B1 (en) * 1993-07-09 2000-02-02 Cygnus, Inc. Method and device for providing nicotine replacement therapy transdermally/transbuccally
US6024974A (en) * 1995-01-06 2000-02-15 Noven Pharmaceuticals, Inc. Composition and methods for transdermal delivery of acid labile drugs
WO1996040085A2 (en) 1995-06-07 1996-12-19 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
US5906830A (en) * 1995-09-08 1999-05-25 Cygnus, Inc. Supersaturated transdermal drug delivery systems, and methods for manufacturing the same
TW411277B (en) * 1996-05-13 2000-11-11 Hisamitsu Pharmaceutical Co Percutaneous tape preparation containing fentanyl
US5985317A (en) * 1996-09-06 1999-11-16 Theratech, Inc. Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents
US5928666A (en) * 1996-11-12 1999-07-27 Cygnus Inc. Crystalline form of estradiol and pharmaceutical formulations comprising same
DE19653606A1 (de) * 1996-12-20 1998-06-25 Roehm Gmbh Haft- und Bindemittel aus (Meth)acrylatpolymer, organischer Säure und Weichmacher
DE19653605C2 (de) * 1996-12-20 2002-11-28 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme und dessen Verwendung zur Herstellung eines transdermalen Therapiesystems
US5948433A (en) * 1997-08-21 1999-09-07 Bertek, Inc. Transdermal patch
IT1294748B1 (it) 1997-09-17 1999-04-12 Permatec Tech Ag Formulazione per un dispositivo transdermico
DE19827732A1 (de) * 1998-06-22 1999-12-23 Rottapharm Bv Transdermales System vom Matrix-Typ zur Abgabe von Wirkstoffen mit einer hohen Abgaberate von Steroid-Hormonen und die Verwendung eines derartigen Systems zur Hormonersatztherapie
DE19828273B4 (de) * 1998-06-25 2005-02-24 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System, enthaltend Hormone und Kristallisationsinhibitoren
AU778992B2 (en) 1998-12-07 2004-12-23 Agi Therapeutics Research Limited Transdermal patch for delivering volatile liquid drugs
FR2793689B1 (fr) * 1999-05-19 2001-08-24 Pf Medicament Dispositif transdermique pour l'administration de testosterone ou d'un de ses derives
KR20010036685A (ko) * 1999-10-11 2001-05-07 김윤 펜타닐을 함유하는 매트릭스형 경피투여제
WO2001064149A1 (en) * 2000-02-29 2001-09-07 Jie Zhang Improved transdermal drug patch
US20020119187A1 (en) * 2000-09-29 2002-08-29 Cantor Adam S. Composition for the transdermal delivery of fentanyl
NZ528148A (en) * 2001-03-16 2006-02-24 Alza Corp Transdermal patch for administering fentanyl
DE10141651B4 (de) 2001-08-24 2007-02-15 Lts Lohmann Therapie-Systeme Ag Transdermales Therapeutisches System (TTS) mit dem Wirkstoff Fentanyl und Verfahren zu seiner Herstellung
CA2460352C (en) * 2001-08-17 2013-05-14 Lavipharm Laboratories Inc. Composition and transdermal drug delivery device
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
US6893655B2 (en) * 2001-10-09 2005-05-17 3M Innovative Properties Co. Transdermal delivery devices
US6958446B2 (en) * 2002-04-17 2005-10-25 Agilent Technologies, Inc. Compliant and hermetic solder seal
US20040086551A1 (en) * 2002-10-30 2004-05-06 Miller Kenneth J. Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl

Also Published As

Publication number Publication date
US20060210617A1 (en) 2006-09-21
ES2249197T3 (es) 2011-09-06
CY1112582T1 (el) 2016-02-10
US20090041831A1 (en) 2009-02-12
EP1585470A2 (en) 2005-10-19
US20070259027A1 (en) 2007-11-08
US20120145320A1 (en) 2012-06-14
US20070166365A1 (en) 2007-07-19
ES2249197T1 (es) 2006-04-01
SI1585470T1 (sl) 2011-10-28
DE03781469T1 (de) 2006-08-10
AU2003288977A1 (en) 2004-06-07
US8449907B2 (en) 2013-05-28
CA2503722A1 (en) 2004-05-21
CA2503722C (en) 2012-05-22
EP1585470A4 (en) 2008-06-18
US7556823B2 (en) 2009-07-07
WO2004041324A3 (en) 2004-07-22
JP2006513160A (ja) 2006-04-20
WO2004041324A2 (en) 2004-05-21
US20130319595A1 (en) 2013-12-05
HK1075816A1 (en) 2005-12-30
PT1585470E (pt) 2011-08-25
JP5069402B2 (ja) 2012-11-07
EP1585470B1 (en) 2011-06-01
AU2003288977A8 (en) 2004-06-07
US20090238861A1 (en) 2009-09-24
ATE511393T1 (de) 2011-06-15
US20040086551A1 (en) 2004-05-06

Similar Documents

Publication Publication Date Title
DK1585470T3 (da) Transdermal afgivelse af fentanyl
MY151020A (en) Transdermal therapeutic system
ATE474617T1 (de) Medizinproduktsysteme
RS50510B (sr) Formulacije koje sadrže ekteinascidin i disaharid
ATE461217T1 (de) Glp-1-verbindungen
LTC1608344I2 (lt) Per burną vartojamos kladribino kompozicijos
IS7997A (is) Granisetron lyfjaplástur
DE602005017753D1 (de) Mittel für die transdermale verabreichung von nikotin
NO20052739D0 (no) CCR5-antagonister som medikamenter
HRP20080564T3 (en) Dihydrotetrabenazines and pharmaceutical compositions containing them
DE602005019944D1 (de) Druckempfindliche Klebstoffzusammensetzung und druckempfindliche Klebefilme
DE60215898D1 (de) Druckempfindliche Silikonklebezusammensetzung und druckempfindliches Klebeband
DE602005000717D1 (de) Druckempfindliches Klebeband
DE60208114D1 (de) Entfernbare druckempfindliche Klebstoff-zusammensetzungen und -folien
DK1373256T3 (da) CCR5-antagonister, der er nyttige til behandling af AIDS
DK1372624T3 (da) Lægemiddel på basis af tramadol
DE602004029518D1 (de) Zusammensetzungen zur Haarbehandlung enthaltend einen druckempfindlichen Silikonklebstoff
DE60330006D1 (de) Druckempfindliches Klebeband
TW200613343A (en) Novel prepolymers for improved surface modification of contact lenses
DE50202537D1 (de) Haftklebstoff, enthaltend Vinylpyrrolidon
BR0312978A (pt) Dispositivo dental de micro-malha revestido, sobre-revestido com particulado embutido
DK1603584T3 (da) Aplidine til behandling af multipelt myelom
EA200501565A1 (ru) Предназначенная для перорального приёма лекарственная форма для антагонистов протонного насоса
DE602005013530D1 (de) Dentalkleberzusammensetzung
AU2003230034A1 (en) Transdermal delivery device for the administration of fentanyl