DK1583524T3 - Bis(thiohydrazidamid)-forbindelser til behandling af multilægemiddel-resistent cancer - Google Patents

Bis(thiohydrazidamid)-forbindelser til behandling af multilægemiddel-resistent cancer

Info

Publication number
DK1583524T3
DK1583524T3 DK04702560T DK04702560T DK1583524T3 DK 1583524 T3 DK1583524 T3 DK 1583524T3 DK 04702560 T DK04702560 T DK 04702560T DK 04702560 T DK04702560 T DK 04702560T DK 1583524 T3 DK1583524 T3 DK 1583524T3
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DK
Denmark
Prior art keywords
substituted
group
aryl group
bonded
taken together
Prior art date
Application number
DK04702560T
Other languages
Danish (da)
English (en)
Inventor
Keizo Koya
Lijun Sun
Yaming Wu
Timoty Korbut
Dan Zhou
Zhenjian Du
Shoujun Chen
Noriaki Tatsuta
Guiqing Liang
Mitsunori Ono
Original Assignee
Synta Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synta Pharmaceuticals Corp filed Critical Synta Pharmaceuticals Corp
Application granted granted Critical
Publication of DK1583524T3 publication Critical patent/DK1583524T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK04702560T 2003-01-15 2004-01-15 Bis(thiohydrazidamid)-forbindelser til behandling af multilægemiddel-resistent cancer DK1583524T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44040603P 2003-01-15 2003-01-15

Publications (1)

Publication Number Publication Date
DK1583524T3 true DK1583524T3 (da) 2006-12-27

Family

ID=32771813

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04702560T DK1583524T3 (da) 2003-01-15 2004-01-15 Bis(thiohydrazidamid)-forbindelser til behandling af multilægemiddel-resistent cancer

Country Status (13)

Country Link
US (1) US7763658B2 (enExample)
EP (1) EP1583524B1 (enExample)
JP (1) JP4852409B2 (enExample)
AT (1) ATE336991T1 (enExample)
AU (1) AU2004206865B2 (enExample)
CA (1) CA2512797C (enExample)
CY (1) CY1106246T1 (enExample)
DE (1) DE602004002087T2 (enExample)
DK (1) DK1583524T3 (enExample)
ES (1) ES2271839T3 (enExample)
PT (1) PT1583524E (enExample)
TW (1) TWI330079B (enExample)
WO (1) WO2004064826A1 (enExample)

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US20100009929A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
US20100028339A1 (en) 2004-03-29 2010-02-04 Cheng Jin Q Compositions including triciribine and trastuzumab and methods of use thereof
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US8618170B2 (en) * 2007-11-09 2013-12-31 Synta Pharmaceuticals Corp. Oral formulations of bis(thiohydrazide amides)
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US8581004B2 (en) 2008-02-21 2013-11-12 Synta Pharmaceuticals Corp. Compounds for treating proliferative disorders
WO2009123704A2 (en) * 2008-03-31 2009-10-08 Synta Pharmaceuticals Corp. Process for preparing bis(thiohydrazide amides)
US8461199B2 (en) * 2008-10-22 2013-06-11 Synta Pharmaceuticals Corp. Transition metal complexes of a bis[thio-hydrazide amide] compound
KR20110073613A (ko) 2008-10-22 2011-06-29 신타 파마슈티칼스 코프. 비스(티오하이드라자이드 아마이드) 화합물의 전이금속착체
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Also Published As

Publication number Publication date
PT1583524E (pt) 2006-12-29
AU2004206865B2 (en) 2006-07-13
HK1084024A1 (en) 2006-07-21
TW200418449A (en) 2004-10-01
ES2271839T3 (es) 2007-04-16
WO2004064826A1 (en) 2004-08-05
TWI330079B (en) 2010-09-11
EP1583524B1 (en) 2006-08-23
DE602004002087D1 (de) 2006-10-05
JP4852409B2 (ja) 2012-01-11
US7763658B2 (en) 2010-07-27
AU2004206865A1 (en) 2004-08-05
JP2006515626A (ja) 2006-06-01
EP1583524A1 (en) 2005-10-12
CA2512797C (en) 2012-02-21
CY1106246T1 (el) 2011-06-08
CA2512797A1 (en) 2004-08-05
ATE336991T1 (de) 2006-09-15
US20040225016A1 (en) 2004-11-11
DE602004002087T2 (de) 2007-03-08

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