ATE336991T1 - Bis(thio-hydrazid amid) verbindungen zur behandlung von mehrfach resistenten krebs - Google Patents

Bis(thio-hydrazid amid) verbindungen zur behandlung von mehrfach resistenten krebs

Info

Publication number
ATE336991T1
ATE336991T1 AT04702560T AT04702560T ATE336991T1 AT E336991 T1 ATE336991 T1 AT E336991T1 AT 04702560 T AT04702560 T AT 04702560T AT 04702560 T AT04702560 T AT 04702560T AT E336991 T1 ATE336991 T1 AT E336991T1
Authority
AT
Austria
Prior art keywords
substituted
group
aryl group
bonded
taken together
Prior art date
Application number
AT04702560T
Other languages
German (de)
English (en)
Inventor
Keizo Koya
Lijun Sun
Yaming Wu
Timoty Korbut
Dan Zhou
Zhenjian Du
Shoujun Chen
Noriaki Tatsuta
Guiqing Liang
Mitsunori Ono
Original Assignee
Synta Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synta Pharmaceuticals Corp filed Critical Synta Pharmaceuticals Corp
Application granted granted Critical
Publication of ATE336991T1 publication Critical patent/ATE336991T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT04702560T 2003-01-15 2004-01-15 Bis(thio-hydrazid amid) verbindungen zur behandlung von mehrfach resistenten krebs ATE336991T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44040603P 2003-01-15 2003-01-15

Publications (1)

Publication Number Publication Date
ATE336991T1 true ATE336991T1 (de) 2006-09-15

Family

ID=32771813

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04702560T ATE336991T1 (de) 2003-01-15 2004-01-15 Bis(thio-hydrazid amid) verbindungen zur behandlung von mehrfach resistenten krebs

Country Status (13)

Country Link
US (1) US7763658B2 (enExample)
EP (1) EP1583524B1 (enExample)
JP (1) JP4852409B2 (enExample)
AT (1) ATE336991T1 (enExample)
AU (1) AU2004206865B2 (enExample)
CA (1) CA2512797C (enExample)
CY (1) CY1106246T1 (enExample)
DE (1) DE602004002087T2 (enExample)
DK (1) DK1583524T3 (enExample)
ES (1) ES2271839T3 (enExample)
PT (1) PT1583524E (enExample)
TW (1) TWI330079B (enExample)
WO (1) WO2004064826A1 (enExample)

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LT2574341T (lt) 2004-03-29 2017-09-11 University Of South Florida Navikų ir vėžio efektyvus gydymas triciribino fosfatu
US20110008327A1 (en) 2004-03-29 2011-01-13 Cheng Jin Q Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US20100009929A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
US20100028339A1 (en) 2004-03-29 2010-02-04 Cheng Jin Q Compositions including triciribine and trastuzumab and methods of use thereof
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US8618170B2 (en) * 2007-11-09 2013-12-31 Synta Pharmaceuticals Corp. Oral formulations of bis(thiohydrazide amides)
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US8581004B2 (en) 2008-02-21 2013-11-12 Synta Pharmaceuticals Corp. Compounds for treating proliferative disorders
WO2009123704A2 (en) * 2008-03-31 2009-10-08 Synta Pharmaceuticals Corp. Process for preparing bis(thiohydrazide amides)
US8461199B2 (en) * 2008-10-22 2013-06-11 Synta Pharmaceuticals Corp. Transition metal complexes of a bis[thio-hydrazide amide] compound
KR20110073613A (ko) 2008-10-22 2011-06-29 신타 파마슈티칼스 코프. 비스(티오하이드라자이드 아마이드) 화합물의 전이금속착체
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Also Published As

Publication number Publication date
PT1583524E (pt) 2006-12-29
AU2004206865B2 (en) 2006-07-13
HK1084024A1 (en) 2006-07-21
TW200418449A (en) 2004-10-01
ES2271839T3 (es) 2007-04-16
WO2004064826A1 (en) 2004-08-05
TWI330079B (en) 2010-09-11
EP1583524B1 (en) 2006-08-23
DE602004002087D1 (de) 2006-10-05
JP4852409B2 (ja) 2012-01-11
US7763658B2 (en) 2010-07-27
AU2004206865A1 (en) 2004-08-05
JP2006515626A (ja) 2006-06-01
EP1583524A1 (en) 2005-10-12
DK1583524T3 (da) 2006-12-27
CA2512797C (en) 2012-02-21
CY1106246T1 (el) 2011-06-08
CA2512797A1 (en) 2004-08-05
US20040225016A1 (en) 2004-11-11
DE602004002087T2 (de) 2007-03-08

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