DK157387A - Substiturede 4-amino-3-hydroxysmoersyrederivater ogfysiologisk acceptable salte deraf, deres fremstilling og anvendelse - Google Patents

Substiturede 4-amino-3-hydroxysmoersyrederivater ogfysiologisk acceptable salte deraf, deres fremstilling og anvendelse

Info

Publication number
DK157387A
DK157387A DK157387A DK157387A DK157387A DK 157387 A DK157387 A DK 157387A DK 157387 A DK157387 A DK 157387A DK 157387 A DK157387 A DK 157387A DK 157387 A DK157387 A DK 157387A
Authority
DK
Denmark
Prior art keywords
amino
substituted
preparation
acceptable salts
acid derivatives
Prior art date
Application number
DK157387A
Other languages
English (en)
Other versions
DK157387D0 (da
Inventor
Helmut Wegmann
Adalbert Wagner
Heinz-Werner Kleemann
Dieter Ruppert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of DK157387D0 publication Critical patent/DK157387D0/da
Publication of DK157387A publication Critical patent/DK157387A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
DK157387A 1986-03-29 1987-03-27 Substiturede 4-amino-3-hydroxysmoersyrederivater ogfysiologisk acceptable salte deraf, deres fremstilling og anvendelse DK157387A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863610593 DE3610593A1 (de) 1986-03-29 1986-03-29 Substituierte 4-amino-3-hydroxybuttersaeure-derivate verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung

Publications (2)

Publication Number Publication Date
DK157387D0 DK157387D0 (da) 1987-03-27
DK157387A true DK157387A (da) 1987-09-30

Family

ID=6297500

Family Applications (1)

Application Number Title Priority Date Filing Date
DK157387A DK157387A (da) 1986-03-29 1987-03-27 Substiturede 4-amino-3-hydroxysmoersyrederivater ogfysiologisk acceptable salte deraf, deres fremstilling og anvendelse

Country Status (5)

Country Link
EP (1) EP0239874A3 (da)
JP (1) JPS62258349A (da)
DE (1) DE3610593A1 (da)
DK (1) DK157387A (da)
PT (1) PT84565B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2533905B2 (ja) * 1987-03-11 1996-09-11 三共株式会社 レニン阻害活性を有するペプチド誘導体
JPH03500886A (ja) * 1987-11-16 1991-02-28 ジ・アップジョン・カンパニー アミノ酸およびヒドロキシジカルボン酸を含有するレニン抑制ペプチド類
ES2086341T3 (es) * 1989-09-12 1996-07-01 Hoechst Ag Derivados de aminoacidos con propiedades inhibidoras de la renina, procedimiento para su preparacion, agentes que los contienen y su utilizacion.
JP2887560B2 (ja) * 1994-04-21 1999-04-26 参天製薬株式会社 新規含硫黄アミノ酸誘導体
US6992081B2 (en) 2000-03-23 2006-01-31 Elan Pharmaceuticals, Inc. Compounds to treat Alzheimer's disease
CA2401749A1 (en) 2000-03-23 2001-09-27 Elan Pharmaceuticals, Inc. Compounds and methods to treat alzheimer's disease
US6846813B2 (en) 2000-06-30 2005-01-25 Pharmacia & Upjohn Company Compounds to treat alzheimer's disease
CA2410972A1 (en) 2000-06-30 2002-01-10 Elan Pharmaceuticals, Inc. Compounds to treat alzheimer's disease

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1254699A (en) * 1984-03-12 1989-05-23 Jasjit S. Bindra Renin inhibitors containing statine or derivatives thereof
EP0163237A3 (en) * 1984-05-29 1988-04-27 Merck & Co. Inc. Di- and tri-peptidal renin inhibitors
EP0486478A3 (en) * 1984-08-06 1992-08-12 The Upjohn Company Renin-inhibiting peptides
SU1676454A3 (ru) * 1984-11-30 1991-09-07 Санкио Компани Лимитед (Фирма) Способ получени пептидов или их фармацевтически приемлемых солей
DE3601248A1 (de) * 1986-01-17 1987-07-23 Hoechst Ag Substituierte 4-amino-3-hydroxybuttersaeure-derivate, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung

Also Published As

Publication number Publication date
DK157387D0 (da) 1987-03-27
JPS62258349A (ja) 1987-11-10
PT84565A (de) 1987-04-01
EP0239874A3 (de) 1989-08-30
EP0239874A2 (de) 1987-10-07
DE3610593A1 (de) 1987-10-01
PT84565B (pt) 1989-11-10

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Legal Events

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PBP Patent lapsed