DK157244C - Calciferolderivater, disse derivater til brug som farmaceutisk aktive stoffer, disse derivater til brug som antiproliferative og differentieringsinducerende aktive stoffer, samt laegemiddel indeholdende disse - Google Patents
Calciferolderivater, disse derivater til brug som farmaceutisk aktive stoffer, disse derivater til brug som antiproliferative og differentieringsinducerende aktive stoffer, samt laegemiddel indeholdende disseInfo
- Publication number
- DK157244C DK157244C DK053785A DK53785A DK157244C DK 157244 C DK157244 C DK 157244C DK 053785 A DK053785 A DK 053785A DK 53785 A DK53785 A DK 53785A DK 157244 C DK157244 C DK 157244C
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- active substances
- differentient
- calciferold
- antiproliferative
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title 2
- 230000001028 anti-proliverative effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
- C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
- C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
- C07C35/32—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a (4.3.0) system, e.g. indenols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/26—Radicals substituted by doubly bound oxygen or sulfur atoms or by two such atoms singly bound to the same carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57816084A | 1984-02-08 | 1984-02-08 | |
| US57816084 | 1984-02-08 | ||
| US68212584A | 1984-12-17 | 1984-12-17 | |
| US68212584 | 1984-12-17 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK53785D0 DK53785D0 (da) | 1985-02-06 |
| DK53785A DK53785A (da) | 1985-08-09 |
| DK157244B DK157244B (da) | 1989-11-27 |
| DK157244C true DK157244C (da) | 1990-04-23 |
Family
ID=27077449
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK053785A DK157244C (da) | 1984-02-08 | 1985-02-06 | Calciferolderivater, disse derivater til brug som farmaceutisk aktive stoffer, disse derivater til brug som antiproliferative og differentieringsinducerende aktive stoffer, samt laegemiddel indeholdende disse |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0154185B1 (de) |
| JP (1) | JPH0735365B2 (de) |
| AU (1) | AU575373B2 (de) |
| CA (1) | CA1311501C (de) |
| DE (1) | DE3565401D1 (de) |
| DK (1) | DK157244C (de) |
| IE (1) | IE57917B1 (de) |
| IL (1) | IL74264A (de) |
| NZ (1) | NZ211071A (de) |
| PH (1) | PH19845A (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL77668A (en) * | 1986-01-21 | 1989-03-31 | Teva Pharma | Production of cholecalciferol derivatives and novel intermediates used therefor |
| GB2229921B (en) * | 1989-04-05 | 1992-12-16 | Chugai Pharmaceutical Co Ltd | Treatment for hyperparathyroidism with use of vitamin d derivatives |
| CA2062520C (en) * | 1991-03-11 | 1998-08-11 | Hector F. Deluca | Synthesis of 1-alpha-hydroxy-secosterol compounds |
| AU650751B2 (en) * | 1991-05-28 | 1994-06-30 | Wisconsin Alumni Research Foundation | Novel synthesis of 19-nor vitamin D compounds |
| US5300705A (en) * | 1993-03-18 | 1994-04-05 | Hoffmann-La Roche Inc. | Process for the preparation of 1α,25,26-trihydroxy-22-ene-cholecalciferol |
| JP4752110B2 (ja) * | 2000-12-25 | 2011-08-17 | 住友化学株式会社 | トリフルオロプロペニル化合物の製造法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4069321A (en) * | 1975-10-14 | 1978-01-17 | Merck & Co., Inc. | Blocked cholecalciferol and dihydrotachysterol 3 derivatives |
| EP0086350A3 (de) * | 1982-02-12 | 1984-11-28 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung von Cholesterinderivaten |
| IL67881A0 (en) * | 1982-02-12 | 1983-06-15 | Sparamedica Ag | Pharmaceutical compositions including certain cholecalciferol derivatives |
| JPS58210017A (ja) * | 1982-05-31 | 1983-12-07 | Kureha Chem Ind Co Ltd | 抗腫瘍剤 |
| ATE90564T1 (de) * | 1982-06-30 | 1993-07-15 | Gen Hospital Corp | Vitamin d glycoside. |
| ATE34977T1 (de) * | 1983-01-28 | 1988-06-15 | Hoffmann La Roche | Verfahren zur herstellung von cholecalciferolderivaten. |
-
1985
- 1985-02-06 IL IL74264A patent/IL74264A/xx not_active IP Right Cessation
- 1985-02-06 EP EP85101254A patent/EP0154185B1/de not_active Expired
- 1985-02-06 DE DE8585101254T patent/DE3565401D1/de not_active Expired
- 1985-02-06 AU AU38469/85A patent/AU575373B2/en not_active Ceased
- 1985-02-06 DK DK053785A patent/DK157244C/da not_active IP Right Cessation
- 1985-02-07 NZ NZ211071A patent/NZ211071A/en unknown
- 1985-02-07 CA CA000473719A patent/CA1311501C/en not_active Expired - Fee Related
- 1985-02-07 PH PH31827A patent/PH19845A/en unknown
- 1985-02-07 IE IE298/85A patent/IE57917B1/en not_active IP Right Cessation
- 1985-02-08 JP JP60022091A patent/JPH0735365B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| IL74264A (en) | 1988-08-31 |
| IL74264A0 (en) | 1985-05-31 |
| DK53785D0 (da) | 1985-02-06 |
| PH19845A (en) | 1986-07-22 |
| NZ211071A (en) | 1988-04-29 |
| DK53785A (da) | 1985-08-09 |
| AU3846985A (en) | 1985-08-15 |
| EP0154185A1 (de) | 1985-09-11 |
| DE3565401D1 (de) | 1988-11-10 |
| EP0154185B1 (de) | 1988-10-05 |
| IE850298L (en) | 1985-08-08 |
| CA1311501C (en) | 1992-12-15 |
| JPH0735365B2 (ja) | 1995-04-19 |
| JPS60248664A (ja) | 1985-12-09 |
| IE57917B1 (en) | 1993-05-19 |
| DK157244B (da) | 1989-11-27 |
| AU575373B2 (en) | 1988-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |