DK156575C - Fremgangsmaade til fremstilling af 3-hydroxy-3-cephem- eller 3-oxo-cepham-carboxylsyrederivater - Google Patents

Fremgangsmaade til fremstilling af 3-hydroxy-3-cephem- eller 3-oxo-cepham-carboxylsyrederivater

Info

Publication number
DK156575C
DK156575C DK061976A DK61976A DK156575C DK 156575 C DK156575 C DK 156575C DK 061976 A DK061976 A DK 061976A DK 61976 A DK61976 A DK 61976A DK 156575 C DK156575 C DK 156575C
Authority
DK
Denmark
Prior art keywords
cepham
cephem
oxo
hydroxy
preparing
Prior art date
Application number
DK061976A
Other languages
Danish (da)
English (en)
Other versions
DK156575B (da
DK61976A (da
Inventor
Teruji Tsuji
Yoshio Hamashima
Mitsuru Yoshioka
Masayuki Narisada
Hiroshi Tanida
Taichiro Komeno
Wataru Nagata
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27457226&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK156575(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP50019612A external-priority patent/JPS5198265A/ja
Priority claimed from JP50022229A external-priority patent/JPS51105051A/ja
Priority claimed from JP50028452A external-priority patent/JPS609516B2/ja
Priority claimed from JP50033808A external-priority patent/JPS5817460B2/ja
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of DK61976A publication Critical patent/DK61976A/da
Priority to DK76882A priority Critical patent/DK76882A/da
Publication of DK156575B publication Critical patent/DK156575B/da
Application granted granted Critical
Publication of DK156575C publication Critical patent/DK156575C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK061976A 1975-02-17 1976-02-16 Fremgangsmaade til fremstilling af 3-hydroxy-3-cephem- eller 3-oxo-cepham-carboxylsyrederivater DK156575C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK76882A DK76882A (da) 1975-02-17 1982-02-22 Mellemprodukter til dannelse af en sephemring og fremgangsmaader til fremstilling deraf

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP1961275 1975-02-17
JP50019612A JPS5198265A (pt) 1975-02-17 1975-02-17
JP2222975 1975-02-21
JP50022229A JPS51105051A (pt) 1975-02-21 1975-02-21
JP2845275 1975-03-07
JP50028452A JPS609516B2 (ja) 1975-03-07 1975-03-07 セフエム骨格の環化製法
JP50033808A JPS5817460B2 (ja) 1975-03-20 1975-03-20 チアゾリンカンノ カイカンホウホウ
JP3380875 1975-03-20

Publications (3)

Publication Number Publication Date
DK61976A DK61976A (da) 1976-08-18
DK156575B DK156575B (da) 1989-09-11
DK156575C true DK156575C (da) 1990-02-05

Family

ID=27457226

Family Applications (1)

Application Number Title Priority Date Filing Date
DK061976A DK156575C (da) 1975-02-17 1976-02-16 Fremgangsmaade til fremstilling af 3-hydroxy-3-cephem- eller 3-oxo-cepham-carboxylsyrederivater

Country Status (24)

Country Link
US (4) US4079181A (pt)
AR (1) AR225878A1 (pt)
AU (1) AU508160B2 (pt)
BE (1) BE838656A (pt)
BG (5) BG27557A4 (pt)
CA (5) CA1136132A (pt)
CH (5) CH627160A5 (pt)
DD (5) DD127899A5 (pt)
DE (1) DE2606278A1 (pt)
DK (1) DK156575C (pt)
ES (1) ES445250A1 (pt)
FR (1) FR2334669A1 (pt)
GB (3) GB1548641A (pt)
GR (1) GR60437B (pt)
IE (1) IE42479B1 (pt)
IL (5) IL49048A (pt)
MX (1) MX3818E (pt)
NL (1) NL190721C (pt)
NZ (1) NZ180037A (pt)
PH (1) PH18022A (pt)
PT (1) PT64806B (pt)
RO (4) RO68460A (pt)
SE (4) SE421691B (pt)
YU (5) YU40272B (pt)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
US4579684A (en) * 1975-02-20 1986-04-01 Ciba-Geigy Corporation Process for the manufacture of enol derivatives
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
US4550162A (en) * 1975-02-20 1985-10-29 Ciba-Geigy Corporation Process for the manufacture of enol derivatives
GB1543048A (en) * 1976-02-04 1979-03-28 Beecham Group Ltd 4-mercapto-3-phenoxyacetamido-2-azetidinone
US4271305A (en) * 1979-02-01 1981-06-02 Eli Lilly And Company Thiazolinoazetidinones and process therefor
JPS55133355A (en) * 1979-04-03 1980-10-17 Shionogi & Co Ltd Inversion of 3-amino group of beta-lactam ring
US4518531A (en) * 1979-04-30 1985-05-21 Eli Lilly And Company Allylic chlorination process and compounds prepared thereby
CA1145339A (en) * 1979-04-30 1983-04-26 Eli Lilly And Company Allylic chlorination process and compounds prepared thereby
CA1148938A (en) * 1979-05-08 1983-06-28 John R. Corfield Preparation of cephalosporins and intermediates employed therein
US4237279A (en) * 1979-07-27 1980-12-02 Eli Lilly And Company Crystalline 3-hydroxycephalosporin solvates
EP0065488B1 (de) * 1981-05-19 1985-08-14 Ciba-Geigy Ag Verfahren zur Herstellung von 4-Thio-azetidinon-Verbindungen
FR2511376A1 (fr) * 1981-08-17 1983-02-18 Rhone Poulenc Sante Nouveaux derives de la cephalosporine et leur prepration
JPS5832884A (ja) * 1981-08-20 1983-02-25 Otsuka Chem Co Ltd ３−エキソメチレンセフアム誘導体の製造方法
JPS59101485A (ja) * 1982-11-29 1984-06-12 Otsuka Chem Co Ltd アセチジノン誘導体
US4533497A (en) * 1982-12-27 1985-08-06 Eli Lilly And Company N-ethylidene azetidinones
KR850000291B1 (ko) * 1983-02-07 1985-03-16 한국과학기술원 3-메틸렌 세팜 화합물의 제조방법
JPS59164771A (ja) * 1983-03-10 1984-09-17 Otsuka Chem Co Ltd 塩素化アゼチジノン誘導体の製造方法
EP0133670A3 (de) * 1983-08-09 1985-12-18 Bayer Ag Verfahren zur Herstellung von 7-Acylamino-3-hydrocy-cephem-4-carbonsäuren und 7-Acylamino-3-hydroxy-1-de-thia-1-oxacephem-4-carbonsäuren
DE3725375A1 (de) * 1987-07-31 1989-02-09 Bayer Ag Stabile oxapenem-3-carbonsaeuren
JP3007986B2 (ja) * 1990-03-02 2000-02-14 大塚化学株式会社 β―ラクタム誘導体の製法
EP0445822B1 (en) * 1990-03-08 1997-06-04 Otsuka Kagaku Kabushiki Kaisha Thiazolinoazetidinone derivative and process for preparing 2-exo-methylene-penam derivative thereform
US5604222A (en) * 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) * 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters
IT1277048B1 (it) * 1995-12-06 1997-11-04 3 Exo S R L Procedimento per la preparazione di cefalosporine attraverso ciclizzazione riduttiva dicarbonilica per trattamento con
US5986091A (en) * 1996-03-13 1999-11-16 Otsuka Kagaku Kabushiki Kaisha Process for preparation of β-lactam compounds
EP2209474A4 (en) 2007-10-09 2013-07-24 Sopharmia Inc BROAD SPECTRUM BETA-LACTAMASE INHIBITORS
CN101525341B (zh) * 2009-04-01 2012-07-04 浙江东邦药业有限公司 一种3-羟基头孢化合物的制备方法
WO2014165126A2 (en) 2013-03-12 2014-10-09 Sopharmia, Inc. Derivatized 3-styryl-cephalosporins
CN108727409A (zh) * 2017-04-24 2018-11-02 浙江省化工研究院有限公司 一种3-羟基头孢菌素的制备方法
CN115397807B (zh) * 2020-04-17 2024-08-13 帝斯曼知识产权资产管理有限公司 用于制备取代的烯胺化合物的方法
CN111647638A (zh) * 2020-04-17 2020-09-11 江苏正泰药业有限公司 一种7-anca的制备工艺

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862164A (en) * 1971-02-03 1975-01-21 Lilly Co Eli Thiazolidine azetidinones
GB1457421A (en) * 1973-01-04 1976-12-01 Glaxo Lab Ltd Cepham derivatives
AU498131B2 (en) * 1974-02-26 1979-02-15 Ciba-Geigy Ag Production of cephems by cyclization
JPS5188955A (pt) * 1975-01-30 1976-08-04
CA1136132A (en) * 1975-02-17 1982-11-23 Teruji Tsuji Cyclization to form cephem ring and intermediates therefor
US4147864A (en) * 1975-02-20 1979-04-03 Ciba-Geigy Corporation Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds
AT342197B (de) * 1975-02-20 1978-03-28 Ciba Geigy Ag Neues verfahren zur herstellung von 3-cephemverbindungen
JPS5214789A (en) * 1975-07-22 1977-02-03 Shionogi & Co Ltd Process for preparing 3-substiuted cephem compounds by ring closure
US4008230A (en) * 1975-10-29 1977-02-15 Eli Lilly And Company Process for preparing 3-hydroxy cephalosporins
JPS6019315B2 (ja) * 1976-01-23 1985-05-15 塩野義製薬株式会社 アゼチジノン化合物
GB1529913A (en) * 1976-02-04 1978-10-25 Beecham Group Ltd Beta-lactam compounds
US4264597A (en) * 1978-06-06 1981-04-28 Masashi Hashimoto Cephalosporin analogues and processes for the preparation thereof

Also Published As

Publication number Publication date
IE42479L (en) 1976-08-17
NZ180037A (en) 1979-11-01
YU40414B (en) 1985-12-31
DD127901A5 (de) 1977-10-19
FR2334669B1 (pt) 1981-12-31
DE2606278C2 (pt) 1989-05-03
CA1144924A (en) 1983-04-19
BG24948A3 (en) 1978-06-15
CA1077936A (en) 1980-05-20
GR60437B (en) 1978-05-26
BG25216A3 (en) 1978-08-10
BE838656A (fr) 1976-06-16
SE7907812L (sv) 1979-09-20
SE444811B (sv) 1986-05-12
DK156575B (da) 1989-09-11
GB1548642A (en) 1979-07-18
AR225878A1 (es) 1982-05-14
NL190721B (nl) 1994-02-16
ES445250A1 (es) 1977-06-16
RO75006A (ro) 1980-10-30
IL56050A0 (en) 1979-01-31
US4440683A (en) 1984-04-03
SE421691B (sv) 1982-01-25
FR2334669A1 (fr) 1977-07-08
DD127899A5 (de) 1977-10-19
IL56049A0 (en) 1979-01-31
AU1118176A (en) 1977-08-25
DE2606278A1 (de) 1976-08-26
YU174182A (en) 1983-01-21
YU174282A (en) 1983-01-21
CH628031A5 (en) 1982-02-15
CH634579A5 (en) 1983-02-15
BG25076A3 (en) 1978-07-12
YU40272B (en) 1985-12-31
IL49048A0 (en) 1976-04-30
CA1095026A (en) 1981-02-03
IL57541A0 (en) 1979-10-31
IE42479B1 (en) 1980-08-13
YU40411B (en) 1985-12-31
CH628030A5 (en) 1982-02-15
GB1548643A (en) 1979-07-18
IL49048A (en) 1981-12-31
MX3818E (es) 1981-07-30
CA1132547A (en) 1982-09-28
CH630074A5 (en) 1982-05-28
YU40412B (en) 1985-12-31
NL7601613A (nl) 1976-08-19
AU508160B2 (en) 1980-03-13
SE7907811L (sv) 1979-09-20
SE7601715L (sv) 1976-08-18
DK61976A (da) 1976-08-18
CH627160A5 (en) 1981-12-31
SE7907813L (sv) 1979-09-20
YU38476A (en) 1983-01-21
YU173882A (en) 1983-01-21
SE434637B (sv) 1984-08-06
RO74936A (fr) 1980-10-30
DD127900A5 (de) 1977-10-19
US4079181A (en) 1978-03-14
DD124986A5 (pt) 1977-03-23
YU173982A (en) 1983-01-21
BG24949A3 (en) 1978-06-15
RO68460A (ro) 1981-08-17
SE434950B (sv) 1984-08-27
IL57418A0 (en) 1979-09-30
YU40413B (en) 1985-12-31
NL190721C (nl) 1994-07-18
PH18022A (en) 1985-03-03
DD127902A5 (de) 1977-10-19
CA1136132A (en) 1982-11-23
US4346218A (en) 1982-08-24
GB1548641A (en) 1979-07-18
PT64806B (en) 1977-07-07
RO74958A (ro) 1980-10-30
BG27557A4 (en) 1979-11-12
US4160085A (en) 1979-07-03

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