DK156396C - 2-(n-pyrrolidino)-3-isobutoxy-n-substituerede phenyl-n-benzyl-propylamin-forbindelser og farmaceutiske midler indeholdende disse - Google Patents
2-(n-pyrrolidino)-3-isobutoxy-n-substituerede phenyl-n-benzyl-propylamin-forbindelser og farmaceutiske midler indeholdende disseInfo
- Publication number
- DK156396C DK156396C DK451884A DK451884A DK156396C DK 156396 C DK156396 C DK 156396C DK 451884 A DK451884 A DK 451884A DK 451884 A DK451884 A DK 451884A DK 156396 C DK156396 C DK 156396C
- Authority
- DK
- Denmark
- Prior art keywords
- pyrrolidino
- isobutoxy
- benzyl
- substituted phenyl
- pharmaceutical agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8315367 | 1983-09-27 | ||
| FR8315367 | 1983-09-27 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK451884D0 DK451884D0 (da) | 1984-09-21 |
| DK451884A DK451884A (da) | 1985-03-28 |
| DK156396B DK156396B (da) | 1989-08-14 |
| DK156396C true DK156396C (da) | 1990-01-08 |
Family
ID=9292587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK451884A DK156396C (da) | 1983-09-27 | 1984-09-21 | 2-(n-pyrrolidino)-3-isobutoxy-n-substituerede phenyl-n-benzyl-propylamin-forbindelser og farmaceutiske midler indeholdende disse |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4645778A (es) |
| EP (1) | EP0138684B1 (es) |
| JP (1) | JPS6092279A (es) |
| KR (1) | KR910003711B1 (es) |
| AT (1) | ATE42100T1 (es) |
| AU (1) | AU569326B2 (es) |
| CA (1) | CA1235417A (es) |
| DE (1) | DE3477664D1 (es) |
| DK (1) | DK156396C (es) |
| ES (1) | ES536264A0 (es) |
| FI (1) | FI78081C (es) |
| GR (1) | GR80481B (es) |
| HU (1) | HU192589B (es) |
| PT (1) | PT79273B (es) |
| ZA (1) | ZA847508B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4727072A (en) * | 1986-02-12 | 1988-02-23 | Mcneilab, Inc. | 3-alkoxy-2-aminopropylamines compositions and use as cardiovascular agents |
| US4758563A (en) * | 1986-02-12 | 1988-07-19 | Mcneilab, Inc. | 3-alkoxy-2-aminopropyamines, cardiovascular compositions and use |
| DE3726633A1 (de) * | 1987-08-11 | 1989-02-23 | Boehringer Mannheim Gmbh | Neue 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| DE3726632A1 (de) * | 1987-08-11 | 1989-05-18 | Boehringer Mannheim Gmbh | 1,2-diamino-verbindungen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten |
| US4888335A (en) * | 1988-07-25 | 1989-12-19 | Mcneilab, Inc. | 3-alkoxy-2-aminopropyl heterocyclic amines and their use as cardiovascular agents |
| US5185362A (en) * | 1988-09-14 | 1993-02-09 | Mcneilab, Inc. | Diphenylamine cardiovascular agents, compositions and use |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US30577A (en) * | 1860-11-06 | Truss-bridge | ||
| BE795735A (fr) * | 1972-03-06 | 1973-06-18 | Cerm Cent Europ Rech Mauvernay | Nouvelles ethylenediamines substituees a activite cardiovasculaire |
| FR2378024A1 (fr) * | 1977-01-25 | 1978-08-18 | Cerm Cent Europ Rech Mauvernay | Nouvelle propylamine substituee, obtention et application |
| GB2087233A (en) * | 1980-09-30 | 1982-05-26 | Akzo Nv | Pharmaceutical compositions containing n-aryl ethanamines having anti-atherothrombosclerotic activity |
| FR2504925A1 (en) * | 1981-05-04 | 1982-11-05 | Cerm Cent Europ Rech Mauvernay | N-2-amino 3-alkoxy or phenoxy-propyl urea and thiourea derivs. - are cardiovascular agents esp. used to treat arrhythmia |
| GB8330197D0 (en) * | 1983-11-11 | 1983-12-21 | Akzo Nv | Ether of n-propanolamine derivative |
-
1984
- 1984-09-21 DK DK451884A patent/DK156396C/da not_active IP Right Cessation
- 1984-09-24 ZA ZA847508A patent/ZA847508B/xx unknown
- 1984-09-26 JP JP59201418A patent/JPS6092279A/ja active Granted
- 1984-09-26 GR GR80481A patent/GR80481B/el unknown
- 1984-09-26 EP EP84401919A patent/EP0138684B1/fr not_active Expired
- 1984-09-26 HU HU843653A patent/HU192589B/hu not_active IP Right Cessation
- 1984-09-26 ES ES536264A patent/ES536264A0/es active Granted
- 1984-09-26 FI FI843785A patent/FI78081C/fi not_active IP Right Cessation
- 1984-09-26 CA CA000464017A patent/CA1235417A/en not_active Expired
- 1984-09-26 AU AU33540/84A patent/AU569326B2/en not_active Ceased
- 1984-09-26 DE DE8484401919T patent/DE3477664D1/de not_active Expired
- 1984-09-26 AT AT84401919T patent/ATE42100T1/de not_active IP Right Cessation
- 1984-09-27 KR KR1019840005947A patent/KR910003711B1/ko active IP Right Grant
- 1984-09-27 US US06/654,921 patent/US4645778A/en not_active Expired - Fee Related
- 1984-09-27 PT PT79273A patent/PT79273B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT79273A (en) | 1984-10-01 |
| EP0138684A3 (en) | 1985-06-19 |
| FI843785L (fi) | 1985-03-28 |
| AU3354084A (en) | 1985-04-04 |
| DK451884A (da) | 1985-03-28 |
| KR910003711B1 (ko) | 1991-06-08 |
| CA1235417A (en) | 1988-04-19 |
| ZA847508B (en) | 1985-05-29 |
| JPS6092279A (ja) | 1985-05-23 |
| FI843785A0 (fi) | 1984-09-26 |
| EP0138684B1 (fr) | 1989-04-12 |
| US4645778A (en) | 1987-02-24 |
| FI78081B (fi) | 1989-02-28 |
| ES8602723A1 (es) | 1985-12-01 |
| ES536264A0 (es) | 1985-12-01 |
| DK156396B (da) | 1989-08-14 |
| KR850002478A (ko) | 1985-05-13 |
| HUT36469A (en) | 1985-09-30 |
| PT79273B (en) | 1986-08-28 |
| AU569326B2 (en) | 1988-01-28 |
| DK451884D0 (da) | 1984-09-21 |
| ATE42100T1 (de) | 1989-04-15 |
| JPH0336836B2 (es) | 1991-06-03 |
| EP0138684A2 (fr) | 1985-04-24 |
| DE3477664D1 (en) | 1989-05-18 |
| HU192589B (en) | 1987-06-29 |
| GR80481B (en) | 1985-01-28 |
| FI78081C (fi) | 1989-06-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |