DK155330C - FREMGANGSMAADE TIL UDVINDING AF ET FARMAKOLOGISK AKTIVT STOF MED ET SMELTEPUNKT PAA 230-232ìC OG SUMFORMLEN C22H34O7 FRA PLANTEN COLEUS FORSKOHLII - Google Patents
FREMGANGSMAADE TIL UDVINDING AF ET FARMAKOLOGISK AKTIVT STOF MED ET SMELTEPUNKT PAA 230-232ìC OG SUMFORMLEN C22H34O7 FRA PLANTEN COLEUS FORSKOHLIIInfo
- Publication number
- DK155330C DK155330C DK397376A DK397376A DK155330C DK 155330 C DK155330 C DK 155330C DK 397376 A DK397376 A DK 397376A DK 397376 A DK397376 A DK 397376A DK 155330 C DK155330 C DK 155330C
- Authority
- DK
- Denmark
- Prior art keywords
- c22h34o7
- preface
- recovery
- procedure
- melting point
- Prior art date
Links
- 235000021508 Coleus Nutrition 0.000 title 1
- OHCQJHSOBUTRHG-KGGHGJDLSA-N FORSKOLIN Chemical compound O=C([C@@]12O)C[C@](C)(C=C)O[C@]1(C)[C@@H](OC(=O)C)[C@@H](O)[C@@H]1[C@]2(C)[C@@H](O)CCC1(C)C OHCQJHSOBUTRHG-KGGHGJDLSA-N 0.000 title 1
- 241000131459 Plectranthus barbatus Species 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 238000002844 melting Methods 0.000 title 1
- 230000008018 melting Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000011084 recovery Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2557784 | 1975-12-22 | ||
| DE2557784A DE2557784C2 (de) | 1975-12-22 | 1975-12-22 | Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK397376A DK397376A (da) | 1977-06-23 |
| DK155330B DK155330B (da) | 1989-03-28 |
| DK155330C true DK155330C (da) | 1989-08-14 |
Family
ID=5965159
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK397376A DK155330C (da) | 1975-12-22 | 1976-09-02 | FREMGANGSMAADE TIL UDVINDING AF ET FARMAKOLOGISK AKTIVT STOF MED ET SMELTEPUNKT PAA 230-232ìC OG SUMFORMLEN C22H34O7 FRA PLANTEN COLEUS FORSKOHLII |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4088659A (enExample) |
| JP (1) | JPS6059237B2 (enExample) |
| AT (1) | AT362053B (enExample) |
| BE (1) | BE847417A (enExample) |
| DE (1) | DE2557784C2 (enExample) |
| DK (1) | DK155330C (enExample) |
| ES (1) | ES454286A1 (enExample) |
| FR (1) | FR2336138A1 (enExample) |
| IL (1) | IL50431A (enExample) |
| IT (1) | IT1065230B (enExample) |
| LU (1) | LU75718A1 (enExample) |
| NL (1) | NL7609954A (enExample) |
| SE (1) | SE439877B (enExample) |
| ZA (1) | ZA765378B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4751224A (en) * | 1983-07-21 | 1988-06-14 | Brown University Research Foundation | Treatment of metastasis |
| AU2690684A (en) * | 1984-02-24 | 1985-09-10 | Kenji Adachi | Methods and pharmaceutical compositions for the treatment of hyperplastic diseases of the skin |
| DE3502686A1 (de) * | 1985-01-26 | 1986-08-14 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von labdan-derivaten und ihre verwendung als arzneimittel |
| DE3502685A1 (de) * | 1985-01-26 | 1986-09-04 | Hoechst Ag, 6230 Frankfurt | Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel |
| US4963537A (en) * | 1985-03-01 | 1990-10-16 | Hoechst-Roussel Pharmaceuticals Inc. | Labdane compounds, pharmaceutical compositions and use |
| IN163242B (enExample) | 1985-05-03 | 1988-08-27 | Hoechst India | |
| AU591196B2 (en) * | 1985-11-15 | 1989-11-30 | Nippon Kayaku Kabushiki Kaisha | Novel forskolin derivatives |
| US4740522A (en) * | 1986-08-28 | 1988-04-26 | Hoechst-Roussel Pharmaceuticals Inc. | Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure |
| US4978678A (en) * | 1986-11-20 | 1990-12-18 | Hoechst-Roussel Pharmaceuticals Inc. | 12-halogenated forskolin derivatives |
| US4920146A (en) * | 1986-12-29 | 1990-04-24 | Hoechst Roussel Pharmaceuticals Inc. | Carbamoyloxylabdane compounds useful in reducing intraocular pressure |
| US5646175A (en) * | 1987-12-28 | 1997-07-08 | Hoechst Marion Roussel, Inc. | Carbamoyloxylabdane compounds |
| US5302730A (en) * | 1987-06-29 | 1994-04-12 | Nippon Kayaku Kk | Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives |
| US4909799A (en) * | 1987-09-18 | 1990-03-20 | Olav Thulesius | Methods for preventing thrombosis; and surgical implant having reduced platelet deposition characteristics |
| US4902696A (en) * | 1987-10-08 | 1990-02-20 | Hoechst-Roussel Pharmaceuticals, Inc. | Synergistic intraocular pressure lowering combinations |
| US5846992A (en) * | 1987-10-08 | 1998-12-08 | Hoechst Marion Roussel, Inc. | Synergistic intraocular pressure lowering combinations |
| US4883793A (en) * | 1988-05-09 | 1989-11-28 | Hoechst-Roussel Pharmaceuticals Inc. | Hydrazinocarbonyloxylabdanes for treating cardiac failure |
| EP0370379B1 (en) * | 1988-11-19 | 1992-09-09 | Hoechst Aktiengesellschaft | Pharmaceutical compositions comprising labdane diterpenoid derivatives and pyrimido(6,1-a) isoquinolin-4-one derivatives and their use |
| US4999351A (en) * | 1989-01-11 | 1991-03-12 | Hoechst-Roussel Pharmaceuticals, Inc. | 7-aryl and heteroaryl ethers of desacetylforskolin |
| US5177207A (en) * | 1989-01-11 | 1993-01-05 | Hoechst-Roussel Pharmaceuticals, Inc. | 7-aryl and heteroaryl ethers of desacetylforskolin |
| US5093336A (en) * | 1989-07-06 | 1992-03-03 | Hoechat-Roussel Pharmaceuticals, Inc. | 6- and 7-deoxyforskolin and derivatives thereof |
| US5145855A (en) * | 1989-07-06 | 1992-09-08 | Hoechst Roussel Pharmaceuticals, Inc. | 6- and 7-deoxyforskolin and derivatives thereof |
| EP0447962A1 (en) * | 1990-03-17 | 1991-09-25 | Hoechst Aktiengesellschaft | Labdanes and process for their preparation |
| FR2665637B1 (fr) * | 1990-08-13 | 1993-08-06 | Lvmh Rech | Composition cosmetique ou pharmaceutique, contenant un extrait de coleus esquirolii, de coleus scutellarioides, de coleus xanthanthus ou un de leurs melanges. |
| US6268206B1 (en) | 1998-11-06 | 2001-07-31 | David Liptak | Bioremediation, detoxication and plant-growth enhancing compositions and methods of making and using such compositions |
| US20080267939A1 (en) * | 2006-09-29 | 2008-10-30 | Jose Angel Olalde Rangel | Synergistic anti-hypertensive phyto-nutraceutical composition |
| EP2424529B1 (en) * | 2009-04-30 | 2016-12-28 | Midwestern University | Novel therapeutic treatments using centhaquin |
| WO2013021399A1 (en) | 2011-08-05 | 2013-02-14 | Council Of Scientific & Industrial Research | Pi marane diterpenes from anisochilus verticillatus |
| HUE033785T2 (en) | 2012-09-14 | 2018-01-29 | Claride Pharma S R L | Composition for the prevention and treatment of acute and recurrent urinary tract infections |
| AU2014287427B2 (en) | 2013-07-08 | 2019-11-21 | Midwestern University | Compositions and methods for treating neuropsychiatric disorders using an endothelin-B receptor agonist |
| USD923470S1 (en) | 2019-07-01 | 2021-06-29 | The Procter & Gamble Company | Absorbent article package |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH503724A (de) * | 1966-05-13 | 1971-02-28 | Hoffmann La Roche | Verfahren zur Herstellung von polycyclischen Verbindungen |
| BE795525A (fr) * | 1972-02-16 | 1973-08-16 | Roure Bertrand Dupont Sa | Naphtopyrannes, leur procede de preparation et leur applications |
-
1975
- 1975-12-22 DE DE2557784A patent/DE2557784C2/de not_active Expired
-
1976
- 1976-09-02 DK DK397376A patent/DK155330C/da not_active IP Right Cessation
- 1976-09-03 SE SE7609756A patent/SE439877B/xx not_active IP Right Cessation
- 1976-09-03 AT AT657276A patent/AT362053B/de not_active IP Right Cessation
- 1976-09-03 LU LU75718A patent/LU75718A1/xx unknown
- 1976-09-07 IT IT26947/76A patent/IT1065230B/it active
- 1976-09-08 ZA ZA765378A patent/ZA765378B/xx unknown
- 1976-09-08 NL NL7609954A patent/NL7609954A/xx not_active Application Discontinuation
- 1976-09-08 IL IL50431A patent/IL50431A/xx unknown
- 1976-09-09 JP JP51107339A patent/JPS6059237B2/ja not_active Expired
- 1976-10-19 BE BE171616A patent/BE847417A/xx not_active IP Right Cessation
- 1976-12-16 ES ES454286A patent/ES454286A1/es not_active Expired
- 1976-12-17 US US05/751,967 patent/US4088659A/en not_active Expired - Lifetime
- 1976-12-22 FR FR7638664A patent/FR2336138A1/fr active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IL50431A0 (en) | 1976-11-30 |
| IL50431A (en) | 1980-01-31 |
| FR2336138B1 (enExample) | 1981-11-20 |
| DK397376A (da) | 1977-06-23 |
| ATA657276A (de) | 1980-09-15 |
| AT362053B (de) | 1981-04-27 |
| DE2557784C2 (de) | 1986-04-17 |
| ES454286A1 (es) | 1978-03-16 |
| FR2336138A1 (fr) | 1977-07-22 |
| DE2557784A1 (de) | 1977-07-07 |
| ZA765378B (en) | 1977-08-31 |
| LU75718A1 (enExample) | 1977-06-15 |
| IT1065230B (it) | 1985-02-25 |
| SE7609756L (sv) | 1977-06-23 |
| NL7609954A (nl) | 1977-06-24 |
| BE847417A (fr) | 1977-04-19 |
| US4088659A (en) | 1978-05-09 |
| JPS6059237B2 (ja) | 1985-12-24 |
| SE439877B (sv) | 1985-07-08 |
| DK155330B (da) | 1989-03-28 |
| JPS5279015A (en) | 1977-07-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |