ES454286A1 - Procedimiento para la obtencion de una sustancia farmacolo- gicamente activa que tiene un punto de fusion de 230-232 grados c y la formula empirica c22h34o7. - Google Patents

Procedimiento para la obtencion de una sustancia farmacolo- gicamente activa que tiene un punto de fusion de 230-232 grados c y la formula empirica c22h34o7.

Info

Publication number
ES454286A1
ES454286A1 ES454286A ES454286A ES454286A1 ES 454286 A1 ES454286 A1 ES 454286A1 ES 454286 A ES454286 A ES 454286A ES 454286 A ES454286 A ES 454286A ES 454286 A1 ES454286 A1 ES 454286A1
Authority
ES
Spain
Prior art keywords
labiatae family
plants belonging
effective substance
compound
labiatae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES454286A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of ES454286A1 publication Critical patent/ES454286A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)

Abstract

Procedimiento para la obtención de una sustancia farmacológicamente activa que tiene un punto de fusión de 230 - 232ºC y la fórmula empírica C22H34O7, caracterizado porque el material de las plantas, eventualmente extraído previamente con un hidrocarburo para la eliminación de las sustancias acompañantes, procedente de una planta de la familia de las labidas, se extrae con un hidrocarburo halogenado o con un alcohol y se purifica de manera conocida.
ES454286A 1975-12-22 1976-12-16 Procedimiento para la obtencion de una sustancia farmacolo- gicamente activa que tiene un punto de fusion de 230-232 grados c y la formula empirica c22h34o7. Expired ES454286A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2557784A DE2557784C2 (de) 1975-12-22 1975-12-22 Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate

Publications (1)

Publication Number Publication Date
ES454286A1 true ES454286A1 (es) 1978-03-16

Family

ID=5965159

Family Applications (1)

Application Number Title Priority Date Filing Date
ES454286A Expired ES454286A1 (es) 1975-12-22 1976-12-16 Procedimiento para la obtencion de una sustancia farmacolo- gicamente activa que tiene un punto de fusion de 230-232 grados c y la formula empirica c22h34o7.

Country Status (14)

Country Link
US (1) US4088659A (es)
JP (1) JPS6059237B2 (es)
AT (1) AT362053B (es)
BE (1) BE847417A (es)
DE (1) DE2557784C2 (es)
DK (1) DK155330C (es)
ES (1) ES454286A1 (es)
FR (1) FR2336138A1 (es)
IL (1) IL50431A (es)
IT (1) IT1065230B (es)
LU (1) LU75718A1 (es)
NL (1) NL7609954A (es)
SE (1) SE439877B (es)
ZA (1) ZA765378B (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751224A (en) * 1983-07-21 1988-06-14 Brown University Research Foundation Treatment of metastasis
WO1985003637A1 (en) * 1984-02-24 1985-08-29 Halprin Kenneth M Methods and pharmaceutical compositions for the treatment of hyperplastic diseases of the skin
DE3502686A1 (de) * 1985-01-26 1986-08-14 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von labdan-derivaten und ihre verwendung als arzneimittel
DE3502685A1 (de) * 1985-01-26 1986-09-04 Hoechst Ag, 6230 Frankfurt Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel
US4963537A (en) * 1985-03-01 1990-10-16 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
IN163242B (es) 1985-05-03 1988-08-27 Hoechst India
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
US4740522A (en) * 1986-08-28 1988-04-26 Hoechst-Roussel Pharmaceuticals Inc. Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure
US4978678A (en) * 1986-11-20 1990-12-18 Hoechst-Roussel Pharmaceuticals Inc. 12-halogenated forskolin derivatives
US5646175A (en) * 1987-12-28 1997-07-08 Hoechst Marion Roussel, Inc. Carbamoyloxylabdane compounds
US4920146A (en) * 1986-12-29 1990-04-24 Hoechst Roussel Pharmaceuticals Inc. Carbamoyloxylabdane compounds useful in reducing intraocular pressure
US5302730A (en) * 1987-06-29 1994-04-12 Nippon Kayaku Kk Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives
US4909799A (en) * 1987-09-18 1990-03-20 Olav Thulesius Methods for preventing thrombosis; and surgical implant having reduced platelet deposition characteristics
US5846992A (en) * 1987-10-08 1998-12-08 Hoechst Marion Roussel, Inc. Synergistic intraocular pressure lowering combinations
US4902696A (en) * 1987-10-08 1990-02-20 Hoechst-Roussel Pharmaceuticals, Inc. Synergistic intraocular pressure lowering combinations
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
DE68902811D1 (de) * 1988-11-19 1992-10-15 Hoechst Ag Pharmazeutische zusammensetzungen mit einem gehalt an labdan-di-terpenoid-derivaten und pyrimido(6,1-a)isochinolin-4-on-derivaten und ihre anwendung.
US5177207A (en) * 1989-01-11 1993-01-05 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US4999351A (en) * 1989-01-11 1991-03-12 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US5093336A (en) * 1989-07-06 1992-03-03 Hoechat-Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
US5145855A (en) * 1989-07-06 1992-09-08 Hoechst Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation
FR2665637B1 (fr) * 1990-08-13 1993-08-06 Lvmh Rech Composition cosmetique ou pharmaceutique, contenant un extrait de coleus esquirolii, de coleus scutellarioides, de coleus xanthanthus ou un de leurs melanges.
US6268206B1 (en) 1998-11-06 2001-07-31 David Liptak Bioremediation, detoxication and plant-growth enhancing compositions and methods of making and using such compositions
US20080267939A1 (en) * 2006-09-29 2008-10-30 Jose Angel Olalde Rangel Synergistic anti-hypertensive phyto-nutraceutical composition
PL2424529T3 (pl) * 2009-04-30 2017-06-30 Midwestern University Nowe postępowania terapeutyczne z zastosowaniem centakwiny
JP6049719B2 (ja) 2011-08-05 2016-12-21 カウンスィル オブ サイエンティフィック アンド インダストリアル リサーチＣｏｕｎｃｉｌ Ｏｆ Ｓｃｉｅｎｔｉｆｉｃ ＆ Ｉｎｄｕｓｔｒｉａｌ Ｒｅｓｅａｒｃｈ Ａｎｉｓｏｃｈｉｌｕｓｖｅｒｔｉｃｉｌｌａｔｕｓ由来のピマランジテルペン
ES2627984T3 (es) 2012-09-14 2017-08-01 Claride Pharma S.R.L. Composición para la prevención y el tratamiento de infecciones agudas y recurrentes del tracto urinario
ES2825101T3 (es) 2013-07-08 2021-05-14 Univ Midwestern Composiciones y métodos para el tratamiento de trastornos neuropsiquiátricos usando un agonista del receptor de la endotelina B
USD923470S1 (en) 2019-07-01 2021-06-29 The Procter & Gamble Company Absorbent article package

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH503724A (de) * 1966-05-13 1971-02-28 Hoffmann La Roche Verfahren zur Herstellung von polycyclischen Verbindungen
BE795525A (fr) * 1972-02-16 1973-08-16 Roure Bertrand Dupont Sa Naphtopyrannes, leur procede de preparation et leur applications

Also Published As

Publication number Publication date
DK155330B (da) 1989-03-28
DE2557784A1 (de) 1977-07-07
SE7609756L (sv) 1977-06-23
DE2557784C2 (de) 1986-04-17
FR2336138B1 (es) 1981-11-20
IL50431A0 (en) 1976-11-30
IL50431A (en) 1980-01-31
SE439877B (sv) 1985-07-08
DK155330C (da) 1989-08-14
ATA657276A (de) 1980-09-15
FR2336138A1 (fr) 1977-07-22
ZA765378B (en) 1977-08-31
BE847417A (fr) 1977-04-19
JPS5279015A (en) 1977-07-02
IT1065230B (it) 1985-02-25
JPS6059237B2 (ja) 1985-12-24
US4088659A (en) 1978-05-09
AT362053B (de) 1981-04-27
LU75718A1 (es) 1977-06-15
DK397376A (da) 1977-06-23
NL7609954A (nl) 1977-06-24

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