IL50431A - Pharmacologically active 5-acetoxy-3-ethenyl dodecahydro-6,10,10b-trihydroxy-3,4,7,7,10a-pentamethyl-1h-naphtho-(2,1b)pyran-1-one obtainined from the plant coleus forkskohlii - Google Patents

Pharmacologically active 5-acetoxy-3-ethenyl dodecahydro-6,10,10b-trihydroxy-3,4,7,7,10a-pentamethyl-1h-naphtho-(2,1b)pyran-1-one obtainined from the plant coleus forkskohlii

Info

Publication number
IL50431A
IL50431A IL50431A IL5043176A IL50431A IL 50431 A IL50431 A IL 50431A IL 50431 A IL50431 A IL 50431A IL 5043176 A IL5043176 A IL 5043176A IL 50431 A IL50431 A IL 50431A
Authority
IL
Israel
Prior art keywords
obtainined
forkskohlii
dodecahydro
naphtho
pentamethyl
Prior art date
Application number
IL50431A
Other languages
English (en)
Other versions
IL50431A0 (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IL50431A0 publication Critical patent/IL50431A0/xx
Publication of IL50431A publication Critical patent/IL50431A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/92Naphthopyrans; Hydrogenated naphthopyrans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL50431A 1975-12-22 1976-09-08 Pharmacologically active 5-acetoxy-3-ethenyl dodecahydro-6,10,10b-trihydroxy-3,4,7,7,10a-pentamethyl-1h-naphtho-(2,1b)pyran-1-one obtainined from the plant coleus forkskohlii IL50431A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2557784A DE2557784C2 (de) 1975-12-22 1975-12-22 Forskolin, Verfahren zu dessen Gewinnung und diese Verbindung enthaltende pharmazeutische Präparate

Publications (2)

Publication Number Publication Date
IL50431A0 IL50431A0 (en) 1976-11-30
IL50431A true IL50431A (en) 1980-01-31

Family

ID=5965159

Family Applications (1)

Application Number Title Priority Date Filing Date
IL50431A IL50431A (en) 1975-12-22 1976-09-08 Pharmacologically active 5-acetoxy-3-ethenyl dodecahydro-6,10,10b-trihydroxy-3,4,7,7,10a-pentamethyl-1h-naphtho-(2,1b)pyran-1-one obtainined from the plant coleus forkskohlii

Country Status (14)

Country Link
US (1) US4088659A (xx)
JP (1) JPS6059237B2 (xx)
AT (1) AT362053B (xx)
BE (1) BE847417A (xx)
DE (1) DE2557784C2 (xx)
DK (1) DK155330C (xx)
ES (1) ES454286A1 (xx)
FR (1) FR2336138A1 (xx)
IL (1) IL50431A (xx)
IT (1) IT1065230B (xx)
LU (1) LU75718A1 (xx)
NL (1) NL7609954A (xx)
SE (1) SE439877B (xx)
ZA (1) ZA765378B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD923470S1 (en) * 2019-07-01 2021-06-29 The Procter & Gamble Company Absorbent article package

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4751224A (en) * 1983-07-21 1988-06-14 Brown University Research Foundation Treatment of metastasis
AU2690684A (en) * 1984-02-24 1985-09-10 Kenji Adachi Methods and pharmaceutical compositions for the treatment of hyperplastic diseases of the skin
DE3502685A1 (de) * 1985-01-26 1986-09-04 Hoechst Ag, 6230 Frankfurt Forskolin, seine analoge und derivate, verfahren zu deren herstellung mittels mikrobieller umwandlungen und die anwendung dieser verbindungen als arzneimittel
DE3502686A1 (de) * 1985-01-26 1986-08-14 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von labdan-derivaten und ihre verwendung als arzneimittel
US4963537A (en) * 1985-03-01 1990-10-16 Hoechst-Roussel Pharmaceuticals Inc. Labdane compounds, pharmaceutical compositions and use
IN163242B (xx) 1985-05-03 1988-08-27 Hoechst India
AU591196B2 (en) * 1985-11-15 1989-11-30 Nippon Kayaku Kabushiki Kaisha Novel forskolin derivatives
US4740522A (en) * 1986-08-28 1988-04-26 Hoechst-Roussel Pharmaceuticals Inc. Oxolabdanes useful as pharmaceuticals for reducing intraocular pressure
US4978678A (en) * 1986-11-20 1990-12-18 Hoechst-Roussel Pharmaceuticals Inc. 12-halogenated forskolin derivatives
US5646175A (en) * 1987-12-28 1997-07-08 Hoechst Marion Roussel, Inc. Carbamoyloxylabdane compounds
US4920146A (en) * 1986-12-29 1990-04-24 Hoechst Roussel Pharmaceuticals Inc. Carbamoyloxylabdane compounds useful in reducing intraocular pressure
US5302730A (en) * 1987-06-29 1994-04-12 Nippon Kayaku Kk Process for the preparation of 6,7-diacyl-7-deacetylforskolin derivatives
US4909799A (en) * 1987-09-18 1990-03-20 Olav Thulesius Methods for preventing thrombosis; and surgical implant having reduced platelet deposition characteristics
US5846992A (en) * 1987-10-08 1998-12-08 Hoechst Marion Roussel, Inc. Synergistic intraocular pressure lowering combinations
US4902696A (en) * 1987-10-08 1990-02-20 Hoechst-Roussel Pharmaceuticals, Inc. Synergistic intraocular pressure lowering combinations
US4883793A (en) * 1988-05-09 1989-11-28 Hoechst-Roussel Pharmaceuticals Inc. Hydrazinocarbonyloxylabdanes for treating cardiac failure
DE68902811D1 (de) * 1988-11-19 1992-10-15 Hoechst Ag Pharmazeutische zusammensetzungen mit einem gehalt an labdan-di-terpenoid-derivaten und pyrimido(6,1-a)isochinolin-4-on-derivaten und ihre anwendung.
US4999351A (en) * 1989-01-11 1991-03-12 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US5177207A (en) * 1989-01-11 1993-01-05 Hoechst-Roussel Pharmaceuticals, Inc. 7-aryl and heteroaryl ethers of desacetylforskolin
US5145855A (en) * 1989-07-06 1992-09-08 Hoechst Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
US5093336A (en) * 1989-07-06 1992-03-03 Hoechat-Roussel Pharmaceuticals, Inc. 6- and 7-deoxyforskolin and derivatives thereof
EP0447962A1 (en) * 1990-03-17 1991-09-25 Hoechst Aktiengesellschaft Labdanes and process for their preparation
FR2665637B1 (fr) * 1990-08-13 1993-08-06 Lvmh Rech Composition cosmetique ou pharmaceutique, contenant un extrait de coleus esquirolii, de coleus scutellarioides, de coleus xanthanthus ou un de leurs melanges.
US6268206B1 (en) 1998-11-06 2001-07-31 David Liptak Bioremediation, detoxication and plant-growth enhancing compositions and methods of making and using such compositions
US20080267939A1 (en) * 2006-09-29 2008-10-30 Jose Angel Olalde Rangel Synergistic anti-hypertensive phyto-nutraceutical composition
PL2424529T3 (pl) * 2009-04-30 2017-06-30 Midwestern University Nowe postępowania terapeutyczne z zastosowaniem centakwiny
WO2013021399A1 (en) 2011-08-05 2013-02-14 Council Of Scientific & Industrial Research Pi marane diterpenes from anisochilus verticillatus
PT2895180T (pt) 2012-09-14 2017-06-23 Claride Pharma S R L Composição para a prevenção e o tratamento de infeções agudas e recorrentes do trato urinário
US10561704B2 (en) 2013-07-08 2020-02-18 Midwestern University Compositions and methods for treating neuropsychiatric disorders using an endothelin-B receptor agonist

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH503724A (de) * 1966-05-13 1971-02-28 Hoffmann La Roche Verfahren zur Herstellung von polycyclischen Verbindungen
BE795525A (fr) * 1972-02-16 1973-08-16 Roure Bertrand Dupont Sa Naphtopyrannes, leur procede de preparation et leur applications

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD923470S1 (en) * 2019-07-01 2021-06-29 The Procter & Gamble Company Absorbent article package
USD928608S1 (en) 2019-07-01 2021-08-24 The Procter & Gamble Company Absorbent article package
USD934679S1 (en) 2019-07-01 2021-11-02 The Procter & Gamble Company Absorbent article package
USD939954S1 (en) 2019-07-01 2022-01-04 The Procter & Gamble Company Absorbent article package

Also Published As

Publication number Publication date
DE2557784C2 (de) 1986-04-17
US4088659A (en) 1978-05-09
ES454286A1 (es) 1978-03-16
AT362053B (de) 1981-04-27
FR2336138A1 (fr) 1977-07-22
SE439877B (sv) 1985-07-08
IL50431A0 (en) 1976-11-30
ATA657276A (de) 1980-09-15
DK155330C (da) 1989-08-14
BE847417A (fr) 1977-04-19
DE2557784A1 (de) 1977-07-07
JPS6059237B2 (ja) 1985-12-24
SE7609756L (sv) 1977-06-23
DK155330B (da) 1989-03-28
LU75718A1 (xx) 1977-06-15
ZA765378B (en) 1977-08-31
JPS5279015A (en) 1977-07-02
FR2336138B1 (xx) 1981-11-20
IT1065230B (it) 1985-02-25
DK397376A (da) 1977-06-23
NL7609954A (nl) 1977-06-24

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