DK153398C - Analogifremgangsmaade til fremstilling af substituerede 4-aminopyridiner - Google Patents
Analogifremgangsmaade til fremstilling af substituerede 4-aminopyridinerInfo
- Publication number
- DK153398C DK153398C DK006880A DK6880A DK153398C DK 153398 C DK153398 C DK 153398C DK 006880 A DK006880 A DK 006880A DK 6880 A DK6880 A DK 6880A DK 153398 C DK153398 C DK 153398C
- Authority
- DK
- Denmark
- Prior art keywords
- alkyl
- carbon atoms
- group
- halogen
- radical
- Prior art date
Links
- 150000003928 4-aminopyridines Chemical class 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 9
- 125000000217 alkyl group Chemical group 0.000 abstract 7
- 229910052736 halogen Inorganic materials 0.000 abstract 4
- 150000002367 halogens Chemical class 0.000 abstract 4
- -1 phenyl-sulfoxy Chemical group 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 150000003254 radicals Chemical class 0.000 abstract 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 150000001350 alkyl halides Chemical class 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- BQIKRTGTPBOIMK-UHFFFAOYSA-N [O]C[O] Chemical compound [O]C[O] BQIKRTGTPBOIMK-UHFFFAOYSA-N 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 125000004397 aminosulfonyl group Chemical group NS(=O)(=O)* 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000003884 phenylalkyl group Chemical group 0.000 abstract 1
- 125000003356 phenylsulfanyl group Chemical group [*]SC1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000001174 sulfone group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792900504 DE2900504A1 (de) | 1979-01-08 | 1979-01-08 | Neue substituierte 4-aminopyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE2900504 | 1979-01-08 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK6880A DK6880A (da) | 1980-07-09 |
| DK153398B DK153398B (da) | 1988-07-11 |
| DK153398C true DK153398C (da) | 1988-12-12 |
Family
ID=6060184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK006880A DK153398C (da) | 1979-01-08 | 1980-01-07 | Analogifremgangsmaade til fremstilling af substituerede 4-aminopyridiner |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4289765A (ru) |
| EP (1) | EP0013408B1 (ru) |
| JP (1) | JPS5594365A (ru) |
| AT (1) | ATE1097T1 (ru) |
| AU (1) | AU530060B2 (ru) |
| CA (1) | CA1138449A (ru) |
| DE (2) | DE2900504A1 (ru) |
| DK (1) | DK153398C (ru) |
| ES (4) | ES487412A1 (ru) |
| FI (1) | FI71131C (ru) |
| IE (1) | IE49038B1 (ru) |
| IL (1) | IL59079A (ru) |
| NO (1) | NO154633C (ru) |
| ZA (1) | ZA8066B (ru) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2465723A1 (fr) * | 1979-05-30 | 1981-03-27 | Italiana Schoum Spa | Nouvelles diphenylpropylamino-pyridines utilisables comme medicaments |
| US4734275A (en) * | 1983-08-19 | 1988-03-29 | Research Corporation | Anti-curare agents |
| DE3514073A1 (de) * | 1985-04-18 | 1986-10-23 | Hoechst Ag, 6230 Frankfurt | Mehrfach substituierte pyridin-1-oxide, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
| DE3541428A1 (de) * | 1985-11-23 | 1987-05-27 | Hoechst Ag | Neue basisch substituierte pyridinverbindungen, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung |
| GB8819307D0 (en) * | 1988-08-13 | 1988-09-14 | Pfizer Ltd | Antiarrhythmic agents |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3547935A (en) * | 1967-08-07 | 1970-12-15 | American Cyanamid Co | Certain nitro-4-pyridinols,n-oxides thereof and derivatives thereof |
| US3517021A (en) * | 1968-05-20 | 1970-06-23 | Engelhard Min & Chem | 4-amino-3-cyanopyridines and methods of preparation |
| GB1386091A (en) * | 1971-03-19 | 1975-03-05 | Ici Ltd | Amino pyridine compounds and compositions |
-
1979
- 1979-01-08 DE DE19792900504 patent/DE2900504A1/de not_active Withdrawn
- 1979-12-21 EP EP79105320A patent/EP0013408B1/de not_active Expired
- 1979-12-21 DE DE7979105320T patent/DE2962972D1/de not_active Expired
- 1979-12-21 AT AT79105320T patent/ATE1097T1/de active
-
1980
- 1980-01-02 ES ES487412A patent/ES487412A1/es not_active Expired
- 1980-01-02 ES ES487411A patent/ES487411A1/es not_active Expired
- 1980-01-02 ES ES487410A patent/ES487410A1/es not_active Expired
- 1980-01-02 ES ES487405A patent/ES487405A1/es not_active Expired
- 1980-01-04 FI FI800030A patent/FI71131C/fi not_active IP Right Cessation
- 1980-01-06 IL IL59079A patent/IL59079A/xx unknown
- 1980-01-07 US US06/109,913 patent/US4289765A/en not_active Expired - Lifetime
- 1980-01-07 ZA ZA00800066A patent/ZA8066B/xx unknown
- 1980-01-07 DK DK006880A patent/DK153398C/da not_active IP Right Cessation
- 1980-01-07 IE IE18/80A patent/IE49038B1/en unknown
- 1980-01-07 CA CA000343136A patent/CA1138449A/en not_active Expired
- 1980-01-07 NO NO800033A patent/NO154633C/no unknown
- 1980-01-07 AU AU54397/80A patent/AU530060B2/en not_active Ceased
- 1980-01-08 JP JP36380A patent/JPS5594365A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| IE800018L (en) | 1980-07-08 |
| DE2962972D1 (en) | 1982-07-15 |
| DK6880A (da) | 1980-07-09 |
| NO800033L (no) | 1980-07-09 |
| EP0013408A1 (de) | 1980-07-23 |
| ES487412A1 (es) | 1980-06-16 |
| ZA8066B (en) | 1980-12-31 |
| EP0013408B1 (de) | 1982-05-26 |
| US4289765A (en) | 1981-09-15 |
| FI71131C (fi) | 1986-11-24 |
| CA1138449A (en) | 1982-12-28 |
| ES487405A1 (es) | 1980-06-16 |
| ES487410A1 (es) | 1980-06-16 |
| FI800030A (fi) | 1980-07-09 |
| IE49038B1 (en) | 1985-07-10 |
| JPS6325584B2 (ru) | 1988-05-26 |
| DK153398B (da) | 1988-07-11 |
| DE2900504A1 (de) | 1980-07-24 |
| AU5439780A (en) | 1980-07-17 |
| NO154633C (no) | 1986-11-19 |
| IL59079A0 (en) | 1980-05-30 |
| ES487411A1 (es) | 1980-07-01 |
| AU530060B2 (en) | 1983-06-30 |
| NO154633B (no) | 1986-08-11 |
| FI71131B (fi) | 1986-08-14 |
| ATE1097T1 (de) | 1982-06-15 |
| JPS5594365A (en) | 1980-07-17 |
| IL59079A (en) | 1984-02-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0463945T3 (da) | Chalcon-derivater, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende derivaterne | |
| MX9205817A (es) | Derivados de benzodiazepina, procedimiento para supreparacion y medicamentos que los contienen | |
| FI873726A0 (fi) | Dihydropyridinfoereningar, foerfaranden foer deras framstaellning och deras anvaendning. | |
| SE8106733L (sv) | 2-substituerade bensofuran-derivat och forfarande for deras framstellning | |
| DK153398C (da) | Analogifremgangsmaade til fremstilling af substituerede 4-aminopyridiner | |
| ES531933A0 (es) | Un procedimiento para preparar un derivado de imidazolinona | |
| SE7901715L (sv) | Nya pyrrolidin-2-on-derivat och herbicida kompositioner innehallande desamma | |
| ATE8633T1 (de) | Vinyl-3-cephalosporinverbindungen und ihre herstellung. | |
| FI874549A0 (fi) | Flera substituenter omfattande pyridin -1-oxider, foerfarande foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning. | |
| DK347379A (da) | Pyrano-heterocycler fremgangsmaader til fremstilling deraf og laegemidler indeholdende disse forbindelser | |
| ATE17490T1 (de) | Dithiino (1,4) (2,3-c) pyrrolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |