DK152048C - Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf. - Google Patents

Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf.

Info

Publication number
DK152048C
DK152048C DK300180A DK300180A DK152048C DK 152048 C DK152048 C DK 152048C DK 300180 A DK300180 A DK 300180A DK 300180 A DK300180 A DK 300180A DK 152048 C DK152048 C DK 152048C
Authority
DK
Denmark
Prior art keywords
carbon atoms
preparation
tetrahydropyridinylin
analogue
derivative
Prior art date
Application number
DK300180A
Other languages
Danish (da)
English (en)
Other versions
DK152048B (da
DK300180A (da
Inventor
Jacques Guillaume
Lucien Nedelec
Claude Dumont
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of DK300180A publication Critical patent/DK300180A/da
Publication of DK152048B publication Critical patent/DK152048B/da
Application granted granted Critical
Publication of DK152048C publication Critical patent/DK152048C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
DK300180A 1979-07-13 1980-07-11 Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf. DK152048C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7918217 1979-07-13
FR7918217A FR2460947A1 (fr) 1979-07-13 1979-07-13 Nouveau derives n-substitues du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant

Publications (3)

Publication Number Publication Date
DK300180A DK300180A (da) 1981-01-14
DK152048B DK152048B (da) 1988-01-25
DK152048C true DK152048C (da) 1988-10-10

Family

ID=9227845

Family Applications (1)

Application Number Title Priority Date Filing Date
DK300180A DK152048C (da) 1979-07-13 1980-07-11 Analogifremgangsmaade til fremstilling af n-substituerede tetrahydropyridinylindolderivater eller farmaceutisk acceptable salte deraf.

Country Status (16)

Country Link
US (1) US4324790A (pt)
EP (1) EP0022705B1 (pt)
JP (2) JPS5615282A (pt)
AT (1) ATE2954T1 (pt)
AU (1) AU535197B2 (pt)
BE (1) BE884279A (pt)
CA (1) CA1145752A (pt)
DE (1) DE3062614D1 (pt)
DK (1) DK152048C (pt)
ES (2) ES8107214A1 (pt)
FR (1) FR2460947A1 (pt)
HU (1) HU184792B (pt)
IE (1) IE50067B1 (pt)
PT (1) PT71549B (pt)
SU (1) SU936813A3 (pt)
ZA (2) ZA803789B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2533924A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
US5214059A (en) * 1989-07-03 1993-05-25 Hoechst-Roussel Pharmaceuticals Incorporated 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
KR20130136010A (ko) 2005-04-13 2013-12-11 네우렉슨 인코포레이티드 Ｎｏｓ 저해 활성을 갖는 치환된 인돌 화합물
EP2010527B1 (en) * 2006-04-13 2013-08-14 Neuraxon Inc. 1,5 and 3,6- substituted indole compounds having nos inhibitory activity
WO2009062319A1 (en) * 2007-11-16 2009-05-22 Neuraxon, Inc. Indole compounds and methods for treating visceral pain
US20090163451A1 (en) * 2007-11-16 2009-06-25 Frank Porreca Methods for treating visceral pain
MX2010005343A (es) * 2007-11-16 2010-08-09 Neuraxon Inc Compuestos indola 3, 5-sustituidos que tienen actividad inhibidora de la re-absorcion y el reciclo de nos y norepinefrina.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2193584B1 (pt) * 1972-07-28 1975-08-08 Roussel Uclaf
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
IL48508A (en) * 1974-12-09 1979-10-31 Roussel Uclaf Pharmaceutical compositions comprising piperidylindole derivatives
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
SU639243A1 (ru) * 1976-12-27 1979-11-25 Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвийской Сср 1-/4-(4-Фторфенил)-4-оксибутил/ -4- (индолил-31)-1,2,3,6-тетрагидропиридин или его соли, обладающие психотропными свойствами
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels

Also Published As

Publication number Publication date
ES8107213A1 (es) 1981-08-16
DK152048B (da) 1988-01-25
IE50067B1 (en) 1986-02-05
JPS5615283A (en) 1981-02-14
ATE2954T1 (de) 1983-04-15
JPS6348872B2 (pt) 1988-09-30
PT71549A (fr) 1980-08-01
PT71549B (fr) 1981-12-14
ES493308A0 (es) 1981-08-16
DE3062614D1 (en) 1983-05-11
BE884279A (fr) 1981-01-12
AU6035980A (en) 1981-01-15
ZA803793B (en) 1981-06-24
US4324790A (en) 1982-04-13
DK300180A (da) 1981-01-14
FR2460947B1 (pt) 1981-07-10
SU936813A3 (ru) 1982-06-15
ZA803789B (en) 1981-06-24
FR2460947A1 (fr) 1981-01-30
HU184792B (en) 1984-10-29
ES493311A0 (es) 1981-08-16
ES8107214A1 (es) 1981-08-16
EP0022705B1 (fr) 1983-04-06
CA1145752A (fr) 1983-05-03
EP0022705A1 (fr) 1981-01-21
JPS6351154B2 (pt) 1988-10-13
IE801456L (en) 1981-01-13
AU535197B2 (en) 1984-03-08
JPS5615282A (en) 1981-02-14

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