JPS5615282A - Tetrahydropyridylindole novel derivatives* their salt* these manufacture* use as drug and composition containing same - Google Patents

Tetrahydropyridylindole novel derivatives* their salt* these manufacture* use as drug and composition containing same

Info

Publication number
JPS5615282A
JPS5615282A JP9408280A JP9408280A JPS5615282A JP S5615282 A JPS5615282 A JP S5615282A JP 9408280 A JP9408280 A JP 9408280A JP 9408280 A JP9408280 A JP 9408280A JP S5615282 A JPS5615282 A JP S5615282A
Authority
JP
Japan
Prior art keywords
carbon atoms
tetrahydropyridylindole
drug
salt
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP9408280A
Other languages
English (en)
Other versions
JPS6351154B2 (ja
Inventor
Giyoomu Jiyatsuku
Nedoretsuku Riyushian
Deyumon Kuroodo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS5615282A publication Critical patent/JPS5615282A/ja
Publication of JPS6351154B2 publication Critical patent/JPS6351154B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
JP9408280A 1979-07-13 1980-07-11 Tetrahydropyridylindole novel derivatives* their salt* these manufacture* use as drug and composition containing same Granted JPS5615282A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7918217A FR2460947A1 (fr) 1979-07-13 1979-07-13 Nouveau derives n-substitues du tetrahydropyridinyl-indole, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant

Publications (2)

Publication Number Publication Date
JPS5615282A true JPS5615282A (en) 1981-02-14
JPS6351154B2 JPS6351154B2 (ja) 1988-10-13

Family

ID=9227845

Family Applications (2)

Application Number Title Priority Date Filing Date
JP9408380A Granted JPS5615283A (en) 1979-07-13 1980-07-11 Tetrahydropyridylindole novel derivatives* their salt* these manufacture* use as drug and composition containing same
JP9408280A Granted JPS5615282A (en) 1979-07-13 1980-07-11 Tetrahydropyridylindole novel derivatives* their salt* these manufacture* use as drug and composition containing same

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP9408380A Granted JPS5615283A (en) 1979-07-13 1980-07-11 Tetrahydropyridylindole novel derivatives* their salt* these manufacture* use as drug and composition containing same

Country Status (16)

Country Link
US (1) US4324790A (ja)
EP (1) EP0022705B1 (ja)
JP (2) JPS5615283A (ja)
AT (1) ATE2954T1 (ja)
AU (1) AU535197B2 (ja)
BE (1) BE884279A (ja)
CA (1) CA1145752A (ja)
DE (1) DE3062614D1 (ja)
DK (1) DK152048C (ja)
ES (2) ES8107214A1 (ja)
FR (1) FR2460947A1 (ja)
HU (1) HU184792B (ja)
IE (1) IE50067B1 (ja)
PT (1) PT71549B (ja)
SU (1) SU936813A3 (ja)
ZA (2) ZA803793B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2533924A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
US5214059A (en) * 1989-07-03 1993-05-25 Hoechst-Roussel Pharmaceuticals Incorporated 2-(aminoaryl) indoles and indolines as topical antiinflammatory agents for the treatment of skin disorders
US5846982A (en) * 1996-06-14 1998-12-08 Eli Lilly And Company Inhibition of serotonin reuptake
ATE489138T1 (de) * 2005-04-13 2010-12-15 Neuraxon Inc Substituierte indolverbindungen mit nos-hemmender aktivität
US7989447B2 (en) * 2006-04-13 2011-08-02 Neuraxon, Inc. 1,5 and 3,6-substituted indole compounds having NOS inhibitory activity
AU2008321353A1 (en) * 2007-11-16 2009-05-22 The Arizona Board Of Regents On Behalf Of The University Of Arizona Methods for treating visceral pain
EP2220074A4 (en) * 2007-11-16 2012-01-04 Neuraxon Inc 3,5-SUBSTITUTED INDOL COMPOUNDS WITH NOS AND NOREPINEPHRINE RECOVERY-HEMDERING EFFECT
MX356032B (es) * 2007-11-16 2018-04-11 Neuraxon Inc Compuestos indola y métodos para tratar el dolor visceral.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4962481A (ja) * 1972-07-28 1974-06-17
JPS5186475A (ja) * 1974-12-09 1976-07-29 Roussel Uclaf

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2322470A1 (de) * 1973-05-04 1974-11-21 Boehringer Sohn Ingelheim Neue indolyl-piperidino-(bzw. 1,2,5,6tetrahydro-pyridyl-)butyrophenone und verfahren zu ihrer herstellung
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
SU639243A1 (ru) * 1976-12-27 1979-11-25 Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвийской Сср 1-/4-(4-Фторфенил)-4-оксибутил/ -4- (индолил-31)-1,2,3,6-тетрагидропиридин или его соли, обладающие психотропными свойствами
FR2444678A2 (fr) * 1978-12-22 1980-07-18 Roussel Uclaf Nouveau procede de preparation de derives du piperidyl-indole et de leurs sels

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4962481A (ja) * 1972-07-28 1974-06-17
JPS5186475A (ja) * 1974-12-09 1976-07-29 Roussel Uclaf

Also Published As

Publication number Publication date
AU6035980A (en) 1981-01-15
EP0022705A1 (fr) 1981-01-21
ATE2954T1 (de) 1983-04-15
ZA803789B (en) 1981-06-24
FR2460947B1 (ja) 1981-07-10
CA1145752A (fr) 1983-05-03
DK152048B (da) 1988-01-25
ES493311A0 (es) 1981-08-16
HU184792B (en) 1984-10-29
IE50067B1 (en) 1986-02-05
ES493308A0 (es) 1981-08-16
DK300180A (da) 1981-01-14
US4324790A (en) 1982-04-13
BE884279A (fr) 1981-01-12
DK152048C (da) 1988-10-10
PT71549B (fr) 1981-12-14
FR2460947A1 (fr) 1981-01-30
JPS6348872B2 (ja) 1988-09-30
PT71549A (fr) 1980-08-01
SU936813A3 (ru) 1982-06-15
ES8107214A1 (es) 1981-08-16
JPS5615283A (en) 1981-02-14
IE801456L (en) 1981-01-13
JPS6351154B2 (ja) 1988-10-13
ZA803793B (en) 1981-06-24
AU535197B2 (en) 1984-03-08
DE3062614D1 (en) 1983-05-11
EP0022705B1 (fr) 1983-04-06
ES8107213A1 (es) 1981-08-16

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