DK151260C - Analogifremgangsmaade til fremstilling af spiro-thienohydantoinderivater. - Google Patents
Analogifremgangsmaade til fremstilling af spiro-thienohydantoinderivater.Info
- Publication number
- DK151260C DK151260C DK019579A DK19579A DK151260C DK 151260 C DK151260 C DK 151260C DK 019579 A DK019579 A DK 019579A DK 19579 A DK19579 A DK 19579A DK 151260 C DK151260 C DK 151260C
- Authority
- DK
- Denmark
- Prior art keywords
- thieno
- spiro
- preparation
- hydantoin derivatives
- analogy procedure
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/870,542 US4127665A (en) | 1978-01-18 | 1978-01-18 | Thienohydantoin derivatives |
US87054278 | 1978-01-18 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK19579A DK19579A (da) | 1979-07-19 |
DK151260B DK151260B (da) | 1987-11-16 |
DK151260C true DK151260C (da) | 1988-05-09 |
Family
ID=25355609
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK019579A DK151260C (da) | 1978-01-18 | 1979-01-17 | Analogifremgangsmaade til fremstilling af spiro-thienohydantoinderivater. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4127665A (hr) |
JP (1) | JPS54109975A (hr) |
BE (1) | BE873500A (hr) |
DE (1) | DE2901477C2 (hr) |
DK (1) | DK151260C (hr) |
FR (1) | FR2415112A1 (hr) |
GB (1) | GB2012759B (hr) |
IE (1) | IE47726B1 (hr) |
IT (1) | IT1110007B (hr) |
LU (1) | LU80795A1 (hr) |
NL (1) | NL176459B (hr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4147797A (en) * | 1978-08-11 | 1979-04-03 | Pfizer Inc. | Spiro-furanohydantoin derivatives |
US4181728A (en) * | 1978-11-16 | 1980-01-01 | Pfizer Inc. | Spiro-polycyclicimidazolidinedione derivatives |
US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
US4210667A (en) * | 1979-04-19 | 1980-07-01 | Pfizer Inc. | Pharmaceutical preparations containing coumarin carboxylic acid derivatives |
AU532110B2 (en) * | 1979-11-13 | 1983-09-15 | Ici Ltd. | Spiro(imidazolidine-4,3:-indoline)-2,2:5-trione derivatives |
ATE10940T1 (de) * | 1981-05-12 | 1985-01-15 | Imperial Chemical Industries Plc | Pyrrolderivate. |
US4540700A (en) * | 1982-04-15 | 1985-09-10 | Alcon Laboratories, Inc. | Treatment of diabetic complications with certain spiro-imidazolidine-diones |
US4464385A (en) * | 1982-04-15 | 1984-08-07 | Alcon Laboratories, Inc. | Treatment of diabetic complications with hydantoins |
US4436745A (en) | 1982-04-15 | 1984-03-13 | Alcon Laboratories, Inc. | Method of inhibiting aldose reductase activity |
US4438272A (en) | 1982-04-15 | 1984-03-20 | Alcon Laboratories, Inc. | Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones |
US5070100A (en) * | 1983-09-14 | 1991-12-03 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives |
US4864028A (en) * | 1983-09-14 | 1989-09-05 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives |
US4537892A (en) * | 1983-09-14 | 1985-08-27 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase |
US5153211A (en) * | 1983-09-14 | 1992-10-06 | Alcon Laboratories, Inc. | Spiro-tricyclicaromatic succinimide derivatives as inhibitors of aldose reductase |
US4680306A (en) * | 1984-07-20 | 1987-07-14 | Pfizer Inc. | Sprio-imidazolones for treatment of diabetes complications |
US4966911A (en) * | 1984-11-20 | 1990-10-30 | Washington Research Foundation | Immunoregulatory agents |
US5340829A (en) * | 1984-11-20 | 1994-08-23 | Washington Research Foundation | Immunoregulatory agents |
JP2708507B2 (ja) * | 1988-04-07 | 1998-02-04 | 株式会社三和化学研究所 | (d)‐6‐フルオロ‐2,3‐ジヒドロ‐2’,5’‐ジオキソ‐スピロ[4H‐1‐ベンゾピラン‐4,4’‐イミダゾリジン]‐2‐カルボキサミド誘導体、これらの製法及び用途 |
EP0536119A4 (en) * | 1989-02-10 | 1993-08-04 | Washington Research Foundation | Immunoregulatory agents |
RU2641648C1 (ru) * | 2009-12-04 | 2018-01-19 | Суновион Фармасьютикалз, Инк. | Полициклические соединения и способы их применения |
KR20190065246A (ko) | 2016-07-29 | 2019-06-11 | 선오비온 파마슈티컬스 인코포레이티드 | 화합물 및 조성물 및 이들의 용도 |
CN116283877A (zh) | 2016-07-29 | 2023-06-23 | 赛诺维信制药公司 | 化合物、组合物及其用途 |
MX2019009763A (es) | 2017-02-16 | 2019-11-21 | Sunovion Pharmaceuticals Inc | Metodos para tratar esquizofrenia. |
SG11202000669VA (en) | 2017-08-02 | 2020-02-27 | Sunovion Pharmaceuticals Inc | Isochroman compounds and uses thereof |
WO2019161238A1 (en) | 2018-02-16 | 2019-08-22 | Sunovion Pharmaceuticals Inc. | Salts, crystal forms, and production methods thereof |
AU2020236225A1 (en) | 2019-03-14 | 2021-09-16 | Sunovion Pharmaceuticals Inc. | Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof |
KR20230003503A (ko) | 2020-04-14 | 2023-01-06 | 선오비온 파마슈티컬스 인코포레이티드 | 신경학적 및 정신의학적 장애의 치료를 위한 (S)-(4,5-디히드로-7H-티에노[2,3-c]피란-7-일)-N-메틸메탄아민 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB796069A (en) * | 1955-12-23 | 1958-06-04 | Ici Ltd | Substituted hydantoins |
DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
-
1978
- 1978-01-18 US US05/870,542 patent/US4127665A/en not_active Expired - Lifetime
-
1979
- 1979-01-16 DE DE2901477A patent/DE2901477C2/de not_active Expired
- 1979-01-16 BE BE0/192915A patent/BE873500A/xx not_active IP Right Cessation
- 1979-01-16 LU LU80795A patent/LU80795A1/xx unknown
- 1979-01-17 JP JP444379A patent/JPS54109975A/ja active Granted
- 1979-01-17 FR FR7901155A patent/FR2415112A1/fr active Granted
- 1979-01-17 DK DK019579A patent/DK151260C/da not_active IP Right Cessation
- 1979-01-17 GB GB791692A patent/GB2012759B/en not_active Expired
- 1979-01-17 NL NLAANVRAGE7900354,A patent/NL176459B/xx not_active IP Right Cessation
- 1979-01-17 IT IT19369/79A patent/IT1110007B/it active
- 1979-01-30 IE IE88/79A patent/IE47726B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
NL7900354A (nl) | 1979-07-20 |
IT1110007B (it) | 1985-12-23 |
DK151260B (da) | 1987-11-16 |
FR2415112B1 (hr) | 1983-01-14 |
DE2901477C2 (de) | 1982-06-09 |
FR2415112A1 (fr) | 1979-08-17 |
DE2901477A1 (de) | 1979-07-19 |
BE873500A (fr) | 1979-07-16 |
US4127665A (en) | 1978-11-28 |
GB2012759B (en) | 1982-05-26 |
LU80795A1 (fr) | 1979-09-07 |
IE47726B1 (en) | 1984-05-30 |
IE790088L (en) | 1979-07-18 |
DK19579A (da) | 1979-07-19 |
NL176459B (nl) | 1984-11-16 |
JPS54109975A (en) | 1979-08-29 |
IT7919369A0 (it) | 1979-01-17 |
GB2012759A (en) | 1979-08-01 |
JPS612067B2 (hr) | 1986-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |