DK1496917T3 - Kombination af en beta-2-adrenoceptoragonist og en aminosukker og anvendelse deraf til behandling af immunmodulerende lidelser - Google Patents

Kombination af en beta-2-adrenoceptoragonist og en aminosukker og anvendelse deraf til behandling af immunmodulerende lidelser

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Publication number
DK1496917T3
DK1496917T3 DK03752710T DK03752710T DK1496917T3 DK 1496917 T3 DK1496917 T3 DK 1496917T3 DK 03752710 T DK03752710 T DK 03752710T DK 03752710 T DK03752710 T DK 03752710T DK 1496917 T3 DK1496917 T3 DK 1496917T3
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DK
Denmark
Prior art keywords
beta
treatment
combination
adrenoceptor agonist
amino sugar
Prior art date
Application number
DK03752710T
Other languages
Danish (da)
English (en)
Inventor
Morten Sloth Weidner
Original Assignee
Astion Dev As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astion Dev As filed Critical Astion Dev As
Application granted granted Critical
Publication of DK1496917T3 publication Critical patent/DK1496917T3/da

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/549—Sugars, nucleosides, nucleotides or nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
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    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
DK03752710T 2002-04-19 2003-04-22 Kombination af en beta-2-adrenoceptoragonist og en aminosukker og anvendelse deraf til behandling af immunmodulerende lidelser DK1496917T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37361502P 2002-04-19 2002-04-19
DKPA200200586 2002-04-19

Publications (1)

Publication Number Publication Date
DK1496917T3 true DK1496917T3 (da) 2006-04-10

Family

ID=49447268

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03752710T DK1496917T3 (da) 2002-04-19 2003-04-22 Kombination af en beta-2-adrenoceptoragonist og en aminosukker og anvendelse deraf til behandling af immunmodulerende lidelser

Country Status (18)

Country Link
US (1) US20050130935A1 (fr)
EP (2) EP1496917B1 (fr)
JP (1) JP2005529151A (fr)
KR (1) KR20050007460A (fr)
CN (1) CN1646143A (fr)
AT (1) ATE311889T1 (fr)
AU (1) AU2003260279B2 (fr)
CA (1) CA2482746A1 (fr)
DE (1) DE60308915T2 (fr)
DK (1) DK1496917T3 (fr)
EA (1) EA007906B1 (fr)
ES (1) ES2254960T3 (fr)
HK (1) HK1073436A1 (fr)
NO (1) NO20045038L (fr)
NZ (1) NZ536447A (fr)
PL (1) PL373190A1 (fr)
SI (1) SI1496917T1 (fr)
WO (1) WO2003097073A1 (fr)

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CA2499170A1 (fr) 2002-09-27 2004-04-08 Children's Medical Center Corporation Procedes et compositions pour le traitement des troubles neurologiques
WO2005089741A2 (fr) * 2004-03-17 2005-09-29 Sosei R&D Ltd. Traitement des troubles inflammatoires et de la douleur a l'aide de beta-aminoalcools
CA2604758C (fr) * 2005-04-13 2014-11-25 Astion Pharma A/S Traitement de maladies du tissu conjonctif cutane
WO2011109340A1 (fr) 2010-03-01 2011-09-09 Nova Southeastern University Nanoparticules d'épinéphrine, leurs méthodes de fabrication et leurs méthodes d'emploi dans le traitement d'états pathologiques sensibles à l'épinéphrine
US20160045457A1 (en) 2005-09-09 2016-02-18 Ousama Rachid Epinephrine fine particles and methods for use thereof for treatment of conditions responsive to epinephrine
WO2007028247A1 (fr) * 2005-09-09 2007-03-15 University Of Manitoba Comprimes d'epinephrine a desintegration rapide destines a une administration orale ou sublinguale
US9877921B2 (en) 2005-09-09 2018-01-30 Nova Southeastern University Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
US8497258B2 (en) 2005-11-12 2013-07-30 The Regents Of The University Of California Viscous budesonide for the treatment of inflammatory diseases of the gastrointestinal tract
GB0604826D0 (en) * 2006-03-09 2006-04-19 Arakis Ltd The treatment of inflammatory disorders and pain
WO2007143676A2 (fr) * 2006-06-05 2007-12-13 Verus Pharmaceuticals, Inc. Posologies d'epinéphrine comprenant des formes pharmaceutiques buccales, linguales ou sublinguales
US20070293580A1 (en) * 2006-06-05 2007-12-20 Malcolm Hill Methods for Buccal, Lingual or Sublingual Dosing Regimens of Epinephrine for the Treatment of Allergic Emergencies
GB0625270D0 (en) * 2006-12-19 2007-01-31 Univ Leicester Angiogenesis
EP3175859B1 (fr) * 2007-05-31 2020-09-23 The Government of the United States of America as represented by The Secretary of the Department of Health and Human Services Mannosamine de n-acétyle pour le traitement d'une maladie renale
GB0805535D0 (en) 2008-03-27 2008-04-30 Univ Leicester Scar prevention
WO2010144865A2 (fr) 2009-06-12 2010-12-16 Meritage Pharma, Inc. Procédés de traitement de troubles gastro-intestinaux
US8716350B2 (en) 2010-03-30 2014-05-06 Algynomics Inc. Compositions and methods for the treatment of somatosensory disorders
JP2013523764A (ja) 2010-03-30 2013-06-17 アルジーノミクス インコーポレイテッド 体性感覚障害治療用の組成物と方法
US20140242177A1 (en) 2011-10-21 2014-08-28 Nova Southeastern University Epinephrine nanoparticles, methods of fabrication thereof, and methods for use thereof for treatment of conditions responsive to epinephrine
CA2876883C (fr) 2012-06-15 2022-11-01 Nova Southeastern University Nanoparticules d'epinephrine, procede pour les fabriquer et procedes pour les utiliser pour le traitement d'affections repondant a l'epinephrine
GB2513297A (en) 2013-03-08 2014-10-29 Univ Leicester Methods
DK2976072T3 (da) 2013-03-22 2021-08-16 Univ Nova Southeastern Epinephrinfinpartikler og fremgangsmåder til anvendelse deraf til behandling af tilstande, der reagerer på epinephrin
CN105601685B (zh) * 2016-01-08 2017-12-26 鲁东大学 含喹唑啉环壳寡糖衍生物及制备方法和生物活性
WO2018000098A1 (fr) * 2016-06-30 2018-01-04 Cipher Pharmaceuticals Inc. Traitement de myopathies inflammatoires

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US4647453A (en) * 1984-10-18 1987-03-03 Peritain, Ltd. Treatment for tissue degenerative inflammatory disease
JP3390477B2 (ja) * 1993-01-25 2003-03-24 生化学工業株式会社 薬剤組成物及びその製造法
AU1533495A (en) * 1994-01-12 1995-08-01 Byk Nederland Bv Phenyl ethanol amine ethers and uses thereof as beta-adreno-receptor agonists
US6255295B1 (en) * 1996-12-23 2001-07-03 Nutramax Laboratories, Inc. Aminosugar, glycosaminoglycan or glycosaminoglycan-like compounds, and s-adenosylmethionine composition for the protection, treatment, repair, and reduction of inflammation of connective tissue
US6046179A (en) * 1998-04-17 2000-04-04 Murch; Simon Composition for and treatment of inflammatory bowel disease by colon administration of N-acetylglucosamine
US6420350B1 (en) * 2001-01-18 2002-07-16 Goen Group, Inc. Weight loss product
US20020136782A1 (en) * 2001-01-18 2002-09-26 Fleischner Albert M. Composition patent for solid-dosage form of weight loss product

Also Published As

Publication number Publication date
KR20050007460A (ko) 2005-01-18
EA007906B1 (ru) 2007-02-27
AU2003260279B2 (en) 2008-01-24
ES2254960T3 (es) 2006-06-16
HK1073436A1 (en) 2005-10-07
EP1496917B1 (fr) 2005-12-07
NO20045038L (no) 2004-11-19
EP1642574A3 (fr) 2008-11-12
WO2003097073A1 (fr) 2003-11-27
SI1496917T1 (sl) 2006-06-30
JP2005529151A (ja) 2005-09-29
PL373190A1 (en) 2005-08-22
CA2482746A1 (fr) 2003-11-27
US20050130935A1 (en) 2005-06-16
DE60308915T2 (de) 2006-12-21
CN1646143A (zh) 2005-07-27
ATE311889T1 (de) 2005-12-15
EP1496917A1 (fr) 2005-01-19
EA200401404A1 (ru) 2005-04-28
AU2003260279A1 (en) 2003-12-02
DE60308915D1 (de) 2006-11-16
EP1642574A2 (fr) 2006-04-05
NZ536447A (en) 2006-05-26

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