DK1495051T3 - Modifikation af egenskaberne af en fibrinmatrix med hensyn til vækst og indvækst af celler - Google Patents
Modifikation af egenskaberne af en fibrinmatrix med hensyn til vækst og indvækst af cellerInfo
- Publication number
- DK1495051T3 DK1495051T3 DK03723513T DK03723513T DK1495051T3 DK 1495051 T3 DK1495051 T3 DK 1495051T3 DK 03723513 T DK03723513 T DK 03723513T DK 03723513 T DK03723513 T DK 03723513T DK 1495051 T3 DK1495051 T3 DK 1495051T3
- Authority
- DK
- Denmark
- Prior art keywords
- fibrinogen
- fibrin
- properties
- lmw
- hmw
- Prior art date
Links
- 102000009123 Fibrin Human genes 0.000 title abstract 7
- 108010073385 Fibrin Proteins 0.000 title abstract 7
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 title abstract 7
- 229950003499 fibrin Drugs 0.000 title abstract 7
- 239000011159 matrix material Substances 0.000 title abstract 3
- 230000010261 cell growth Effects 0.000 title 1
- 230000004048 modification Effects 0.000 title 1
- 238000012986 modification Methods 0.000 title 1
- 102000008946 Fibrinogen Human genes 0.000 abstract 7
- 108010049003 Fibrinogen Proteins 0.000 abstract 7
- 229940012952 fibrinogen Drugs 0.000 abstract 7
- 230000033115 angiogenesis Effects 0.000 abstract 3
- 239000002323 fibrinogen variant Substances 0.000 abstract 2
- 239000000565 sealant Substances 0.000 abstract 2
- 230000012010 growth Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 231100000241 scar Toxicity 0.000 abstract 1
- 230000004614 tumor growth Effects 0.000 abstract 1
- 230000029663 wound healing Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/106—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/363—Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/046—Fibrin; Fibrinogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Surgery (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1020426A NL1020426C2 (nl) | 2002-04-18 | 2002-04-18 | Modificatie van de eigenschappen van een fibrinematrix met betrekking tot groei en ingroei van cellen. |
| PCT/NL2003/000293 WO2003087160A1 (en) | 2002-04-18 | 2003-04-07 | Modification of the properties of a fibrin matrix with respect to growth and ingrowth of cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1495051T3 true DK1495051T3 (da) | 2008-11-10 |
Family
ID=29244993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03723513T DK1495051T3 (da) | 2002-04-18 | 2003-04-07 | Modifikation af egenskaberne af en fibrinmatrix med hensyn til vækst og indvækst af celler |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US7867519B2 (https=) |
| EP (1) | EP1495051B1 (https=) |
| JP (3) | JP5083928B2 (https=) |
| AT (1) | ATE403679T1 (https=) |
| AU (1) | AU2003230455A1 (https=) |
| CA (1) | CA2482893C (https=) |
| DE (1) | DE60322687D1 (https=) |
| DK (1) | DK1495051T3 (https=) |
| NL (1) | NL1020426C2 (https=) |
| WO (1) | WO2003087160A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2514474C (en) | 2003-01-30 | 2014-05-06 | Avner Yayon | Freeze-dried fibrin matrices and methods for preparation thereof |
| US7067123B2 (en) | 2003-04-29 | 2006-06-27 | Musculoskeletal Transplant Foundation | Glue for cartilage repair |
| US7901457B2 (en) | 2003-05-16 | 2011-03-08 | Musculoskeletal Transplant Foundation | Cartilage allograft plug |
| US7335508B2 (en) | 2004-07-22 | 2008-02-26 | Prochon Biotech Ltd. | Porous plasma protein matrices and methods for preparation thereof |
| US7837740B2 (en) | 2007-01-24 | 2010-11-23 | Musculoskeletal Transplant Foundation | Two piece cancellous construct for cartilage repair |
| US7815926B2 (en) | 2005-07-11 | 2010-10-19 | Musculoskeletal Transplant Foundation | Implant for articular cartilage repair |
| JP2009508596A (ja) | 2005-09-19 | 2009-03-05 | ヒストジェニックス コーポレイション | 細胞支持基材及びその調製方法 |
| EP2106263B1 (en) | 2007-01-04 | 2016-12-21 | Hepacore Ltd. | Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof |
| US8435551B2 (en) | 2007-03-06 | 2013-05-07 | Musculoskeletal Transplant Foundation | Cancellous construct with support ring for repair of osteochondral defects |
| WO2009111069A1 (en) | 2008-03-05 | 2009-09-11 | Musculoskeletal Transplant Foundation | Cancellous constructs, cartilage particles and combinations of cancellous constructs and cartilage particles |
| US20110177524A1 (en) | 2008-07-09 | 2011-07-21 | Profibrix Bv | Recombinant Fibrinogen |
| WO2011083154A1 (en) * | 2010-01-08 | 2011-07-14 | Profibrix Bv | Dry powder fibrin sealant |
| ES2524886T3 (es) * | 2010-01-08 | 2014-12-15 | Profibrix Bv | Preparados de fibrinógeno enriquecidos en fibrinógeno con una cadena alfa extendida |
| WO2012140650A2 (en) | 2011-04-12 | 2012-10-18 | Hepacore Ltd. | Conjugates of carboxy polysaccharides with fibroblast growth factors and variants thereof |
| US8999376B2 (en) | 2012-02-03 | 2015-04-07 | Xcede Technologies, Inc. | Tissue patch |
| KR101567053B1 (ko) | 2013-09-30 | 2015-11-09 | 한국원자력의학원 | 방사선 피폭에 의한 간 손상 예측용 바이오마커 및 그 예측방법 |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| US9540548B1 (en) | 2015-08-07 | 2017-01-10 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
| WO2017027378A1 (en) | 2015-08-07 | 2017-02-16 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
| US9833538B2 (en) | 2015-08-07 | 2017-12-05 | Xcede Technologies, Inc. | Adhesive compositions and related methods |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1142581A3 (en) * | 1990-11-27 | 2002-09-11 | American National Red Cross | Tissue sealant and growth factor containing compositions that promote accelerated wound healing |
| CA2188647A1 (en) * | 1994-05-02 | 1995-11-09 | Stewart Anthony Cederholm-Williams | Recombinant fibrin chains, fibrin and fibrin-homologs |
| ATE244584T1 (de) * | 1995-01-16 | 2003-07-15 | Baxter Int | Selbsttragende flächengebilde aus vernetztem fibrin zur hemmung von postoperativen adhäsionen |
| US6037457A (en) * | 1997-01-31 | 2000-03-14 | The University Of North Carolina At Chapel Hill | Method for recombinant fibrinogen production |
| WO1998055140A1 (en) * | 1997-06-05 | 1998-12-10 | Omrix Biopharmaceuticals S.A. | Fibrinogen concentrate from human plasma |
| US6946140B1 (en) * | 1999-02-09 | 2005-09-20 | The Research Foundation Of State University Of New York | Methods and compositions for enhancing fibroblast migration |
| AU4351000A (en) * | 1999-04-15 | 2000-11-02 | Research Foundation Of State University Of New York, The | Cellular matrix system and use thereof |
| WO2000072852A1 (en) * | 1999-06-01 | 2000-12-07 | Bristol-Myers Squibb Company | Prevention of post surgical adhesions using a fibrin monomer sealant |
-
2002
- 2002-04-18 NL NL1020426A patent/NL1020426C2/nl not_active IP Right Cessation
-
2003
- 2003-04-07 AU AU2003230455A patent/AU2003230455A1/en not_active Abandoned
- 2003-04-07 CA CA2482893A patent/CA2482893C/en not_active Expired - Lifetime
- 2003-04-07 US US10/511,700 patent/US7867519B2/en not_active Expired - Lifetime
- 2003-04-07 DK DK03723513T patent/DK1495051T3/da active
- 2003-04-07 JP JP2003584115A patent/JP5083928B2/ja not_active Expired - Lifetime
- 2003-04-07 DE DE60322687T patent/DE60322687D1/de not_active Expired - Lifetime
- 2003-04-07 WO PCT/NL2003/000293 patent/WO2003087160A1/en not_active Ceased
- 2003-04-07 EP EP03723513A patent/EP1495051B1/en not_active Expired - Lifetime
- 2003-04-07 AT AT03723513T patent/ATE403679T1/de active
-
2010
- 2010-04-07 JP JP2010088946A patent/JP5395726B2/ja not_active Expired - Lifetime
- 2010-05-06 JP JP2010106630A patent/JP5248547B2/ja not_active Expired - Lifetime
- 2010-11-24 US US12/953,941 patent/US20110071083A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005538045A (ja) | 2005-12-15 |
| JP2010246543A (ja) | 2010-11-04 |
| CA2482893A1 (en) | 2003-10-23 |
| JP5395726B2 (ja) | 2014-01-22 |
| EP1495051B1 (en) | 2008-08-06 |
| JP2010195805A (ja) | 2010-09-09 |
| JP5248547B2 (ja) | 2013-07-31 |
| DE60322687D1 (de) | 2008-09-18 |
| WO2003087160A1 (en) | 2003-10-23 |
| US7867519B2 (en) | 2011-01-11 |
| CA2482893C (en) | 2014-08-12 |
| US20110071083A1 (en) | 2011-03-24 |
| JP5083928B2 (ja) | 2012-11-28 |
| US20050181972A1 (en) | 2005-08-18 |
| ATE403679T1 (de) | 2008-08-15 |
| AU2003230455A1 (en) | 2003-10-27 |
| NL1020426C2 (nl) | 2003-10-21 |
| EP1495051A1 (en) | 2005-01-12 |
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