DK1715900T3 - Kompositstrukturer, som indeholder hyaluronsyre derivaterne deraf som nye knoglesubstitutter og -transplantater - Google Patents

Kompositstrukturer, som indeholder hyaluronsyre derivaterne deraf som nye knoglesubstitutter og -transplantater

Info

Publication number
DK1715900T3
DK1715900T3 DK04804587.6T DK04804587T DK1715900T3 DK 1715900 T3 DK1715900 T3 DK 1715900T3 DK 04804587 T DK04804587 T DK 04804587T DK 1715900 T3 DK1715900 T3 DK 1715900T3
Authority
DK
Denmark
Prior art keywords
hyaluronic acid
acid derivatives
transplants
composite structures
new bone
Prior art date
Application number
DK04804587.6T
Other languages
English (en)
Inventor
Andrea Pastorello
Daniele Pressato
Original Assignee
Fidia Advanced Biopolymers Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Advanced Biopolymers Srl filed Critical Fidia Advanced Biopolymers Srl
Application granted granted Critical
Publication of DK1715900T3 publication Critical patent/DK1715900T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/42—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
    • A61L27/425—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus containing material, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A61L27/3608—Bone, e.g. demineralised bone matrix [DBM], bone powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • A61L27/3645—Connective tissue
    • A61L27/365—Bones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3821—Bone-forming cells, e.g. osteoblasts, osteocytes, osteoprogenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3834—Cells able to produce different cell types, e.g. hematopoietic stem cells, mesenchymal stem cells, marrow stromal cells, embryonic stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3839—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by the site of application in the body
    • A61L27/3843—Connective tissue
    • A61L27/3847—Bones
DK04804587.6T 2003-11-27 2004-11-26 Kompositstrukturer, som indeholder hyaluronsyre derivaterne deraf som nye knoglesubstitutter og -transplantater DK1715900T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000286A ITPD20030286A1 (it) 2003-11-27 2003-11-27 Strutture composite multistrato contenenti acido ialuronico
PCT/EP2004/053129 WO2005051446A1 (en) 2003-11-27 2004-11-26 Composite structures containing hyaluronic acid the derivatives thereof as new bone substitutes and grafts

Publications (1)

Publication Number Publication Date
DK1715900T3 true DK1715900T3 (da) 2010-05-25

Family

ID=34631181

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04804587.6T DK1715900T3 (da) 2003-11-27 2004-11-26 Kompositstrukturer, som indeholder hyaluronsyre derivaterne deraf som nye knoglesubstitutter og -transplantater

Country Status (9)

Country Link
US (1) US7709018B2 (da)
EP (1) EP1715900B1 (da)
AT (1) ATE454910T1 (da)
CA (1) CA2547461C (da)
DE (1) DE602004025145D1 (da)
DK (1) DK1715900T3 (da)
ES (1) ES2339667T3 (da)
IT (1) ITPD20030286A1 (da)
WO (1) WO2005051446A1 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD20040312A1 (it) * 2004-12-15 2005-03-15 Fidia Advanced Biopolymers Srl Protesi e o supporto per la sostituzione, riparazione, rigenerazione del menisco
ES2329329B1 (es) 2008-05-23 2010-09-17 Institut Quimic De Sarria Cets, Fundacio Privada Pasta termoplastica para la reparacion tejidos vivos.
CA2750605C (en) 2009-01-23 2019-01-22 Royal College Of Surgeons In Ireland Layered scaffold suitable for osteochondral repair
JP5711736B2 (ja) * 2009-07-10 2015-05-07 バイオ２ テクノロジーズ，インク． 生体組織工学のためのデバイスおよび方法
US20110206828A1 (en) * 2009-07-10 2011-08-25 Bio2 Technologies, Inc. Devices and Methods for Tissue Engineering
US9775721B2 (en) 2009-07-10 2017-10-03 Bio2 Technologies, Inc. Resorbable interbody device
IT1401218B1 (it) * 2010-07-14 2013-07-12 Mastelli S R L Composizione ad attivita' bio-rigenerativa, riparativa ed eutrofizzante.
ITAN20110138A1 (it) * 2011-10-12 2012-01-11 Regenyal Lab S R L Sintesi di un gel iniettabile multifasico a base di acido ialuronico monofasico libero e reticolato e di acido ialuronico bifasico associato con idrossiapatite con inibitore della ialuronidasi microincapsulato.
IN2014DN09950A (da) * 2012-05-30 2015-08-14 Klox Technologies Inc
RU2018134453A (ru) * 2012-10-08 2019-05-24 Аптиссен С.А. Стерильный инъецируемый водный состав на основе сшитой гиалуроновой кислоты и гидроксиапатита для терапевтического применения
US10172651B2 (en) 2012-10-25 2019-01-08 Warsaw Orthopedic, Inc. Cortical bone implant
US9265609B2 (en) 2013-01-08 2016-02-23 Warsaw Orthopedic, Inc. Osteograft implant
JP2016514030A (ja) * 2013-03-14 2016-05-19 ジェンザイム・コーポレーション 感熱性骨成長組成物
CA2986702C (en) 2015-05-21 2023-04-04 David Wang Modified demineralized cortical bone fibers
US20200368027A1 (en) 2018-01-02 2020-11-26 Cartiheal (2009) Ltd. Implantation Tool and Protocol for Optimized Solid Substrates Promoting Cell and Tissue Growth
US11369473B2 (en) 2019-04-08 2022-06-28 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
US11779683B2 (en) 2019-04-08 2023-10-10 Loubert S. Suddaby Extended release immunomodulatory implant to facilitate bone morphogenesis
DE202021004032U1 (de) 2020-08-29 2022-10-10 BioScientific Designs d.o.o Ein steriles Medizinprodukt als Knochenersatz, Zubereitung und Verwendung
EP4255517A1 (en) * 2020-12-02 2023-10-11 Anika Therapeutics, Inc. Bioabsorbable textiles and methods for joint function restoration
IT202100027047A1 (it) * 2021-10-21 2023-04-21 The Wave Innovation Group Srls Composizione eterogenea a fasi stratificate di acido ialuronico e suo uso intrarticolare
CN115054728B (zh) * 2022-07-18 2023-11-07 中国科学院大学宁波华美医院 一种仿生骨组织工程支架材料及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5425769A (en) 1990-04-23 1995-06-20 Snyders, Jr.; Robert V. Composition of material for osseous repair
US5645591A (en) 1990-05-29 1997-07-08 Stryker Corporation Synthetic bone matrix
IT1259090B (it) * 1992-04-17 1996-03-11 Fidia Spa Biomaterialli per protesi d'osso
WO1995001181A1 (en) 1993-07-01 1995-01-12 Allelix Biopharmaceuticals Inc. Hyaluronic acid fragments and their therapeutic use
TW369414B (en) 1994-09-30 1999-09-11 Yamanouchi Pharma Co Ltd Bone formation transplant
CA2256400A1 (en) * 1996-05-28 1997-12-04 Brown University Research Foundation Hyaluronan based biodegradable scaffolds for tissue repair
US6165487A (en) 1996-09-30 2000-12-26 Children's Medical Center Corporation Methods and compositions for programming an organic matrix for remodeling into a target tissue
US7019192B2 (en) 1998-02-27 2006-03-28 Musculoskeletal Transplant Foundation Composition for filling bone defects
CA2416481C (en) 2000-07-19 2011-02-15 Osteotech, Inc. Osteoimplant and method of making same
ITPD20010032A1 (it) * 2001-02-09 2002-08-09 Fidia Advanced Biopolymers Srl Innesti ingegnerizzati per la riparazione di difetti osteocondrali

Also Published As

Publication number Publication date
ATE454910T1 (de) 2010-01-15
ES2339667T3 (es) 2010-05-24
EP1715900B1 (en) 2010-01-13
WO2005051446A1 (en) 2005-06-09
DE602004025145D1 (de) 2010-03-04
US7709018B2 (en) 2010-05-04
CA2547461C (en) 2013-12-24
ITPD20030286A1 (it) 2005-05-28
EP1715900A1 (en) 2006-11-02
US20070110819A1 (en) 2007-05-17
CA2547461A1 (en) 2005-06-09

Similar Documents

Publication Publication Date Title
DK1715900T3 (da) Kompositstrukturer, som indeholder hyaluronsyre derivaterne deraf som nye knoglesubstitutter og -transplantater
NZ591338A (en) Platelet-derived growth factor compositions and methods for the treatment of tendon and ligament injuries
EP2664341A3 (en) Native (telopeptide) placental collagen compositions
ITMI20050343A1 (it) Sostituto cartilagineo e osteocindrale comprendente una struttura multistrato e relativo impiego
WO2005110050A3 (en) Tissue scaffold
WO2004039248A3 (en) Repairing or replacing tissues or organs
DE60330181D1 (de) Actriib-fusionspolypeptide und verwendungen dafür
ATE391145T1 (de) Interpenetrierende netzwerke
SI1635731T1 (sl) Postopek preprečevanja kirurških adhezij
DE60238416D1 (de) Plasmaprotein-matritzes und verfahren zu ihrer herstellung
WO2007064772A3 (en) Implantable microbial cellulose materials for various medical applications
WO2007078427A3 (en) Diffusion-hardened medical implant
ES2141145T3 (es) Membranas compuestas para la regeneracion guiada de tejidos.
AU2003291179A1 (en) Bioactive, resorbable scaffolds for tissue engineering
WO2006081435A3 (en) Method of providing readily available cellular material derived from cord blood, and a composition thereof
EP2514445A3 (en) Bioactive hydrogel compositions
WO2004062697A3 (en) Silk fibroin materials and use thereof
WO2004067044A8 (en) Light-activated adhesive composite, system, and methods
WO2007054939A3 (en) Method for non-autologous cartilage regeneration
CU23352A1 (es) Biomateriales compuestos para implantes óseos
WO2003099230A3 (en) Electroprocessed collagen and tissue engineering
DK1085917T3 (da) Biomaterialer indeholdende hyaluronsyrederivater i form af tredimensionale strukturer, som er frie for cellulære komponenter eller produkter deraf, til in vivo-regenerering af vævsceller
GB2454154A (en) Aglet for attachment to a graft material
AU2003284691A1 (en) Calcium phosphate carrying protein, process for producing the same and sustained release protein preparation, artificial bone and tissue enginerring scaffold using the same
AU2003251729A1 (en) Use of antibodies against flt-1 for the treatment of osteoporosis