DK149270C - Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater - Google Patents
Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivaterInfo
- Publication number
- DK149270C DK149270C DK240283A DK240283A DK149270C DK 149270 C DK149270 C DK 149270C DK 240283 A DK240283 A DK 240283A DK 240283 A DK240283 A DK 240283A DK 149270 C DK149270 C DK 149270C
- Authority
- DK
- Denmark
- Prior art keywords
- carbolin
- carboxylic acid
- acid derivatives
- propyl
- preparing beta
- Prior art date
Links
- ARLVFKCLBYUINL-UHFFFAOYSA-N 9h-pyrido[3,4-b]indole-3-carboxylic acid Chemical class N1C2=CC=CC=C2C2=C1C=NC(C(=O)O)=C2 ARLVFKCLBYUINL-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 2
- 239000005557 antagonist Substances 0.000 abstract 1
- 229940049706 benzodiazepine Drugs 0.000 abstract 1
- 150000001557 benzodiazepines Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Emergency Protection Circuit Devices (AREA)
- Testing Of Short-Circuits, Discontinuities, Leakage, Or Incorrect Line Connections (AREA)
Priority Applications (16)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK240283A DK149270C (da) | 1983-05-27 | 1983-05-27 | Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater |
| NO842014A NO159854C (no) | 1983-05-27 | 1984-05-21 | Analogifremgangsm te til fremstilling av terapeutisk aktive beta-karbolin-3-karboksylsyrederivater. |
| IL71887A IL71887A (en) | 1983-05-27 | 1984-05-22 | Ethyl 5-alkoxy-beta-carboline-3-carboxylate derivatives and methods for the preparation thereof |
| DE8484105849T DE3473759D1 (en) | 1983-05-27 | 1984-05-22 | Beta-carbolin-3-carboxylic acid derivatives and methods of preparing them |
| EP84105849A EP0128415B1 (en) | 1983-05-27 | 1984-05-22 | Beta-carbolin-3-carboxylic acid derivatives and methods of preparing them |
| AU28470/84A AU567163B2 (en) | 1983-05-27 | 1984-05-22 | B-carbolin-3-carboxylic acid derivatives |
| AT84105849T ATE36853T1 (de) | 1983-05-27 | 1984-05-22 | Beta-carbolin-3-carbonsaeurederivate und methode zu ihrer herstellung. |
| DK256384A DK149271C (da) | 1983-05-27 | 1984-05-24 | Beta-carbolin-3-carboxylsyrederivater |
| GR74830A GR81580B (cs) | 1983-05-27 | 1984-05-25 | |
| CA000455218A CA1256877A (en) | 1983-05-27 | 1984-05-25 | .beta.-CARBOLIN-3-CARBOXYLIC ACID DERIVATIVES AND METHODS OF PREPARING THEM |
| ES532836A ES532836A0 (es) | 1983-05-27 | 1984-05-25 | Metodo para preparar derivados de acidos b-carbolin-3-barboxilicos |
| FI842112A FI79108C (fi) | 1983-05-27 | 1984-05-25 | Foerfarande foer framstaellning av farmakologiskt aktiva 5-alkoxi- -karbolin-3-karboxylsyraderivat. |
| ZA844003A ZA844003B (en) | 1983-05-27 | 1984-05-25 | Beta-carbolin-3-carboxylic acid derivatives and methods of preparing them |
| HU842037A HU189904B (en) | 1983-05-27 | 1984-05-25 | Process for production of derivatives of beta-carbolin-3-carboxylic acid ethyl ester |
| JP59106707A JPH089614B2 (ja) | 1983-05-27 | 1984-05-28 | β―カルボリン―３―カルボン酸誘導体、その製法及びこれを含有する精神安定剤 |
| US06/746,811 US4748179A (en) | 1983-05-27 | 1985-06-20 | β-carbolin-3-carboxylic acid derivatives and their use as benzodiazepine antagonists |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK240283A DK149270C (da) | 1983-05-27 | 1983-05-27 | Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater |
| DK240283 | 1983-05-27 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK240283D0 DK240283D0 (da) | 1983-05-27 |
| DK240283A DK240283A (da) | 1984-11-28 |
| DK149270B DK149270B (da) | 1986-04-14 |
| DK149270C true DK149270C (da) | 1986-08-25 |
Family
ID=8112124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK240283A DK149270C (da) | 1983-05-27 | 1983-05-27 | Analogifremgangsmaade til fremstilling af beta-carbolin-3-carboxylsyrederivater |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US4748179A (cs) |
| EP (1) | EP0128415B1 (cs) |
| JP (1) | JPH089614B2 (cs) |
| AT (1) | ATE36853T1 (cs) |
| AU (1) | AU567163B2 (cs) |
| CA (1) | CA1256877A (cs) |
| DE (1) | DE3473759D1 (cs) |
| DK (1) | DK149270C (cs) |
| ES (1) | ES532836A0 (cs) |
| FI (1) | FI79108C (cs) |
| GR (1) | GR81580B (cs) |
| HU (1) | HU189904B (cs) |
| IL (1) | IL71887A (cs) |
| NO (1) | NO159854C (cs) |
| ZA (1) | ZA844003B (cs) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3322895A1 (de) * | 1983-06-23 | 1985-01-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue ss-carboline, verfahren zur ihrer herstellung und ihre verwendung als arzneimittel (s) |
| FR2562071B1 (fr) * | 1984-03-30 | 1986-12-19 | Sanofi Sa | Triazolo(4,3-b)pyridazines, procede pour leur preparation et compositions pharmaceutiques les contenant |
| DK240184D0 (da) * | 1984-05-15 | 1984-05-15 | Ferrosan As | Beta-carboline-3-carboxylic acid derivatives and method of preparing the same |
| DE3504045A1 (de) * | 1985-02-04 | 1986-08-07 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur herstellung von ss-carbolinen durch dehydrierung |
| DE3535927A1 (de) * | 1985-10-04 | 1987-04-09 | Schering Ag | 3-vinyl- und 3-ethinyl-ss-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel |
| DE3535928A1 (de) * | 1985-10-04 | 1987-04-09 | Schering Ag | Tetrahydro-(beta)-carboline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4952584A (en) * | 1986-01-11 | 1990-08-28 | Beecham Group P.L.C. | 9H-pyrido[2,B-8]indole-3-carboxylic acid ester compounds having useful pharmaceutical activity |
| US5193732A (en) * | 1991-10-04 | 1993-03-16 | International Business Machines Corporation | Apparatus and methods for making simultaneous electrical connections |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1084257A (cs) * | 1963-11-06 | |||
| NZ194747A (en) * | 1979-08-29 | 1988-11-29 | Schering Ag | 9h-pyrido(3,4-b)indol-3-ylcarboxylic acid derivatives |
| ZA805383B (en) * | 1979-08-29 | 1981-08-26 | Schering Ag | -carbolin-3-carboxylic acid derivatives and methods of preparing the same |
| JPS574987A (en) * | 1980-06-09 | 1982-01-11 | Sankyo Co Ltd | Pyridoindolecarboxylic acid derivative and its preparation |
| JPS6023627B2 (ja) * | 1980-06-09 | 1985-06-08 | 和親 和田 | 柱状物用昇降器具 |
| JPS57123180A (en) * | 1980-12-17 | 1982-07-31 | Schering Ag | 3-substituted beta-carboline, manufacture and psychotropic drug containing same |
| DE3240513A1 (de) * | 1982-10-29 | 1984-05-03 | Schering AG, 1000 Berlin und 4709 Bergkamen | Indolderivate, verfahren zu ihrer herstellung und deren verwendung zur weiterverarbeitung |
-
1983
- 1983-05-27 DK DK240283A patent/DK149270C/da not_active IP Right Cessation
-
1984
- 1984-05-21 NO NO842014A patent/NO159854C/no unknown
- 1984-05-22 AU AU28470/84A patent/AU567163B2/en not_active Ceased
- 1984-05-22 IL IL71887A patent/IL71887A/xx unknown
- 1984-05-22 AT AT84105849T patent/ATE36853T1/de not_active IP Right Cessation
- 1984-05-22 DE DE8484105849T patent/DE3473759D1/de not_active Expired
- 1984-05-22 EP EP84105849A patent/EP0128415B1/en not_active Expired
- 1984-05-25 ZA ZA844003A patent/ZA844003B/xx unknown
- 1984-05-25 CA CA000455218A patent/CA1256877A/en not_active Expired
- 1984-05-25 FI FI842112A patent/FI79108C/fi not_active IP Right Cessation
- 1984-05-25 ES ES532836A patent/ES532836A0/es active Granted
- 1984-05-25 GR GR74830A patent/GR81580B/el unknown
- 1984-05-25 HU HU842037A patent/HU189904B/hu not_active IP Right Cessation
- 1984-05-28 JP JP59106707A patent/JPH089614B2/ja not_active Expired - Lifetime
-
1985
- 1985-06-20 US US06/746,811 patent/US4748179A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK240283A (da) | 1984-11-28 |
| NO842014L (no) | 1984-11-28 |
| ES8505682A1 (es) | 1985-06-16 |
| EP0128415B1 (en) | 1988-08-31 |
| US4748179A (en) | 1988-05-31 |
| DK240283D0 (da) | 1983-05-27 |
| FI79108B (fi) | 1989-07-31 |
| HUT34483A (en) | 1985-03-28 |
| DE3473759D1 (en) | 1988-10-06 |
| AU567163B2 (en) | 1987-11-12 |
| IL71887A0 (en) | 1984-09-30 |
| ATE36853T1 (de) | 1988-09-15 |
| AU2847084A (en) | 1984-11-29 |
| EP0128415A3 (en) | 1985-12-18 |
| CA1256877A (en) | 1989-07-04 |
| NO159854C (no) | 1989-02-15 |
| JPH089614B2 (ja) | 1996-01-31 |
| ZA844003B (en) | 1985-01-30 |
| GR81580B (cs) | 1984-12-11 |
| FI79108C (fi) | 1989-11-10 |
| FI842112L (fi) | 1984-11-28 |
| ES532836A0 (es) | 1985-06-16 |
| EP0128415A2 (en) | 1984-12-19 |
| JPS6041676A (ja) | 1985-03-05 |
| FI842112A0 (fi) | 1984-05-25 |
| IL71887A (en) | 1987-10-30 |
| HU189904B (en) | 1986-08-28 |
| NO159854B (no) | 1988-11-07 |
| DK149270B (da) | 1986-04-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |