DK1467998T3 - Tetracykliske hetaroforbindelser som östrogenreceptormodulatorer - Google Patents

Tetracykliske hetaroforbindelser som östrogenreceptormodulatorer

Info

Publication number
DK1467998T3
DK1467998T3 DK02797167T DK02797167T DK1467998T3 DK 1467998 T3 DK1467998 T3 DK 1467998T3 DK 02797167 T DK02797167 T DK 02797167T DK 02797167 T DK02797167 T DK 02797167T DK 1467998 T3 DK1467998 T3 DK 1467998T3
Authority
DK
Denmark
Prior art keywords
estrogen receptor
receptor modulators
hetero compounds
tetracyclic
tetracyclic hetero
Prior art date
Application number
DK02797167T
Other languages
English (en)
Inventor
Ramesh M Kanojia
Nareshkumar F Jain
Raymond Ng
Zhihua Sui
Jiayi Xu
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of DK1467998T3 publication Critical patent/DK1467998T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30Oestrogens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
DK02797167T 2001-12-19 2002-12-02 Tetracykliske hetaroforbindelser som östrogenreceptormodulatorer DK1467998T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34195701P 2001-12-19 2001-12-19

Publications (1)

Publication Number Publication Date
DK1467998T3 true DK1467998T3 (da) 2006-07-31

Family

ID=23339719

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02797167T DK1467998T3 (da) 2001-12-19 2002-12-02 Tetracykliske hetaroforbindelser som östrogenreceptormodulatorer

Country Status (22)

Country Link
EP (1) EP1467998B1 (da)
JP (1) JP2005513133A (da)
CN (1) CN1620457A (da)
AR (1) AR038661A1 (da)
AT (1) ATE321764T1 (da)
AU (1) AU2002362041A1 (da)
BR (1) BR0215152A (da)
CA (1) CA2471107A1 (da)
CY (1) CY1105361T1 (da)
DE (1) DE60210333T2 (da)
DK (1) DK1467998T3 (da)
ES (1) ES2264737T3 (da)
HK (1) HK1068875A1 (da)
HU (1) HUP0500103A3 (da)
IL (1) IL162295A0 (da)
MX (1) MXPA04006034A (da)
NZ (1) NZ533281A (da)
PL (1) PL371045A1 (da)
PT (1) PT1467998E (da)
RU (1) RU2305099C2 (da)
WO (1) WO2003053977A1 (da)
ZA (1) ZA200405653B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7329654B2 (en) * 2001-12-19 2008-02-12 Janssen Pharmaceutica N.V. Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators
US7105679B2 (en) 2001-12-19 2006-09-12 Kanojia Ramesh M Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators
US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
WO2005073244A1 (en) * 2004-01-22 2005-08-11 Eli Lilly And Company Selective estrogen receptor modulators
AU2005300030B2 (en) * 2004-09-20 2012-01-12 Janssen Pharmaceutica N.V. Novel tetracyclic heteroatom containing derivatives useful as sex steroid hormone receptor modulators
CN101242817B (zh) 2005-06-15 2016-08-31 菲布罗根公司 HIF1α调节剂在治疗癌症中的用途
DE102006024032A1 (de) * 2006-05-23 2007-11-29 Voith Patent Gmbh Anordnung zur Bandregelung
PL2580210T3 (pl) * 2010-06-10 2017-09-29 Seragon Pharmaceuticals, Inc. Modulatory receptora estrogenowego i ich zastosowania
BR112014014124A2 (pt) * 2011-12-14 2017-08-22 Seragon Pharmaceutical Inc Moduladores do receptor de estrogênio fluorados e usos dos mesmos
CN113135884B (zh) * 2020-01-20 2023-03-10 西华大学 一种异色烯类化合物及其制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL124481C (da) * 1964-11-04
CA2214196A1 (en) * 1996-09-26 1998-03-26 Eli Lilly And Company Benzo[b]indeno[2,1-d]thiophene compounds, intermediates, processes, compositions and methods
ES2185054T3 (es) * 1996-12-13 2003-04-16 Chugai Pharmaceutical Co Ltd Derivados de benzopirano.

Also Published As

Publication number Publication date
JP2005513133A (ja) 2005-05-12
RU2004118606A (ru) 2006-01-10
EP1467998A1 (en) 2004-10-20
ATE321764T1 (de) 2006-04-15
WO2003053977A1 (en) 2003-07-03
BR0215152A (pt) 2004-10-19
CY1105361T1 (el) 2010-03-03
MXPA04006034A (es) 2005-03-31
AU2002362041A1 (en) 2003-07-09
CN1620457A (zh) 2005-05-25
IL162295A0 (en) 2005-11-20
ZA200405653B (en) 2006-06-28
DE60210333T2 (de) 2006-11-30
HUP0500103A2 (hu) 2005-05-30
PT1467998E (pt) 2006-08-31
PL371045A1 (en) 2005-06-13
DE60210333D1 (de) 2006-05-18
CA2471107A1 (en) 2003-07-03
EP1467998B1 (en) 2006-03-29
RU2305099C2 (ru) 2007-08-27
HK1068875A1 (en) 2005-05-06
ES2264737T3 (es) 2007-01-16
HUP0500103A3 (en) 2009-01-28
NZ533281A (en) 2007-05-31
AR038661A1 (es) 2005-01-26

Similar Documents

Publication Publication Date Title
DK1173440T3 (da) Tetracycliske azepinoindolforbindelser som 5-HT receptorligander
DE60327767D1 (de) Tricyclische steroidhormonkernrezeptor-modulatoren
PT1444215E (pt) Derivados de 1,2,4-triadiazolio como moduladores do receptor de melanocortina
NO20051042L (no) Pyrimidylsulfonamidderivater som kemokinreseptormodulatorer
NO20042955L (no) Substituerte fenylaftalener som estrogene midler
IS6267A (is) Ný spíróefnasambönd
DK1414440T3 (da) N-phenylpyrrolguanidinderivater som melanocortinreceptorligander
HK1092143A1 (en) Thiazole derivatives as cannabinoid receptor modulators
MA28391B1 (fr) Dérivés de 3-cycloalkylaminopyrrolidine utiles comme modulateurs de récepteurs de chimiokines
NO20015272L (no) Glukokortikoid reseptor modulatorer
DK1668014T3 (da) Kondenserede heterocykliske forbindelser som serotoninreceptormodulatorer
PL374215A1 (en) Selective estrogen receptor modulators
IL172759A0 (en) Pyrrole-2,5-dithione derivatives as liver x receptor modulators
IL172760A0 (en) Pyrrole-2,5-dithione derivatives as liver x receptor modulators
AU2002236114A1 (en) Tricyclic androgen receptor modulator compounds
PL376803A1 (pl) Nowe pochodne tetracykliczne zawierające heteroatomy, jako selektywne modulatory receptora estrogenowego
CY1105361T1 (el) Τετρακυκλικες ετepοενωσεις σαν ρυθμιστες υποδοχεα οιστρογονου
EP1656142A4 (en) 6-CYCLOAMINO-2-QUINOLINONE DERIVATIVES AS MODULATORS ANDROGEN RECEPTOR COMPOUNDS
AU2002335075A1 (en) Estrogen receptor modulators
AU2003231523A1 (en) Estrogen receptor modulators
AU2001270822A1 (en) Imidazolophthalazine derivatives as ligands for gabaa receptors
DK1495030T3 (da) Ikke-steroidale progesteronreceptormodulatorer
NO20015378L (no) Cyklokarbamatderivater som progesteronreseptormodulatorer
NO20032415D0 (no) Forbindelser som er aktive på glukokortikoidreseptor II
AU2002235543A1 (en) Imidazolophthalazine derivatives as ligands for gabaa receptors