DK1440152T3 - 5t4-ligand - Google Patents

5t4-ligand

Info

Publication number
DK1440152T3
DK1440152T3 DK02772604.1T DK02772604T DK1440152T3 DK 1440152 T3 DK1440152 T3 DK 1440152T3 DK 02772604 T DK02772604 T DK 02772604T DK 1440152 T3 DK1440152 T3 DK 1440152T3
Authority
DK
Denmark
Prior art keywords
ligand
Prior art date
Application number
DK02772604.1T
Other languages
English (en)
Inventor
Miles Carroll
Abigail Lamikanra
Alan Kingsman
Original Assignee
Oxford Biomedica Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Biomedica Ltd filed Critical Oxford Biomedica Ltd
Application granted granted Critical
Publication of DK1440152T3 publication Critical patent/DK1440152T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK02772604.1T 2001-11-02 2002-11-04 5t4-ligand DK1440152T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0126378.9A GB0126378D0 (en) 2001-11-02 2001-11-02 Antigen
PCT/GB2002/004965 WO2003038098A2 (en) 2001-11-02 2002-11-04 5t4 ligand

Publications (1)

Publication Number Publication Date
DK1440152T3 true DK1440152T3 (da) 2013-07-29

Family

ID=9925057

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02772604.1T DK1440152T3 (da) 2001-11-02 2002-11-04 5t4-ligand

Country Status (6)

Country Link
US (4) US20050175618A1 (da)
EP (1) EP1440152B1 (da)
DK (1) DK1440152T3 (da)
ES (1) ES2430968T3 (da)
GB (1) GB0126378D0 (da)
WO (1) WO2003038098A2 (da)

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WO2006031653A2 (en) * 2004-09-10 2006-03-23 Wyeth Humanized anti-5t4 antibodies and anti-5t4 antibody / calicheamicin conjugates
AU2007226696C1 (en) * 2006-03-10 2016-02-04 Wyeth Llc Anti-5T4 antibodies and uses thereof
AU2013216628C1 (en) * 2006-03-10 2016-02-04 Wyeth Llc Anti-5t4 antibodies and uses thereof
ES2712732T3 (es) 2009-02-17 2019-05-14 Cornell Res Foundation Inc Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
CA2782333C (en) 2009-12-02 2019-06-04 Imaginab, Inc. J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use
BR112014018192A8 (pt) 2012-01-24 2021-03-02 Epic Sciences Inc método e kit para detecção de células tumorais circulantes 5t4-positivas, bem como métodos de diagnóstico de câncer 5t4-positivo e de seleção para atividade e eficácia de conjugado fármaco-anticorpo para tratamento de câncer
AU2014342610A1 (en) 2013-11-04 2016-06-02 Abbvie Stemcentrx Llc Anti-EFNA4 antibody-drug conjugates
WO2015155345A1 (en) * 2014-04-11 2015-10-15 Medimmune Limited Antibodies and antibody-drug conjugates
TWI707872B (zh) * 2014-05-29 2020-10-21 美商宏觀基因股份有限公司 特異性結合多種癌症抗原的三特異性結合分子和其使用方法
US10680464B2 (en) * 2014-09-02 2020-06-09 Panasonic Intellectual Property Management Co., Ltd. Contactless power receiver, contactless power feeder, and contactless power transmission system provided with same
AU2016304764C1 (en) 2015-08-07 2023-06-01 Imaginab, Inc. Antigen binding constructs to target molecules
MY187325A (en) * 2015-11-24 2021-09-22 Byondis Bv Anti-5t4 antibodies and antibody-drug conjugates
EP3395834A4 (en) * 2015-12-24 2019-10-23 XDCExplorer (Shanghai) Co., Ltd. ANTI-TPBG ANTIBODIES AND ITS PREPARATION METHOD, CONJUGATED AND USE THEREOF
WO2018147960A1 (en) 2017-02-08 2018-08-16 Imaginab, Inc. Extension sequences for diabodies
KR20230166145A (ko) 2017-03-15 2023-12-06 옥스포드 바이오메디카(유케이) 리미티드 방법
BR112020018490A2 (pt) 2018-03-12 2020-12-29 Genmab A/S Anticorpo, imunoconjugado ou conjugado de anticorpo-fármaco, construção de ácido nucléico, vetor de expressão, célula, composição, composição farmacêutica, anticorpo, método, método para produzir um anticorpo, kit de partes, e, anticorpo anti-idiotípico
WO2021048423A1 (en) 2019-09-12 2021-03-18 Genmab A/S Bispecific antibodies binding to 5t4 and cd3 for use in treatment of cancer

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US239400A (en) 1881-03-29 Tobacco-fork
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US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
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WO1989007947A1 (en) 1988-03-04 1989-09-08 Cancer Research Campaign Technology Limited Improvements relating to antigens
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ATE208633T1 (de) * 1994-09-16 2001-11-15 Merck Patent Gmbh Immunokonjugate
AU7435296A (en) * 1995-10-16 1997-05-07 Dana-Farber Cancer Institute Novel expression vectors and methods of use
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EP2042598A1 (en) 1998-11-18 2009-04-01 Oxford Biomedica (UK) Limited 5T4 tumour-associated antigen for use in tumour immunotherapy
DE60040555D1 (de) * 1999-11-18 2008-11-27 Oxford Biomedica Ltd Küle
SE0102327D0 (sv) * 2001-06-28 2001-06-28 Active Biotech Ab A novel engineered superantigen for human therapy
US6875425B2 (en) * 2002-12-12 2005-04-05 Unilever Home & Personal Care Usa Skin lightening agents, compositions and methods
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Also Published As

Publication number Publication date
EP1440152A2 (en) 2004-07-28
US20100310584A1 (en) 2010-12-09
ES2430968T3 (es) 2013-11-22
GB0126378D0 (en) 2002-01-02
US20130236479A1 (en) 2013-09-12
US20050175618A1 (en) 2005-08-11
WO2003038098A3 (en) 2003-06-12
WO2003038098A2 (en) 2003-05-08
EP1440152B1 (en) 2013-04-24
US20090155290A1 (en) 2009-06-18

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