DK1440152T3 - 5t4-ligand - Google Patents

5t4-ligand

Info

Publication number
DK1440152T3
DK1440152T3 DK02772604.1T DK02772604T DK1440152T3 DK 1440152 T3 DK1440152 T3 DK 1440152T3 DK 02772604 T DK02772604 T DK 02772604T DK 1440152 T3 DK1440152 T3 DK 1440152T3
Authority
DK
Denmark
Prior art keywords
ligand
Prior art date
Application number
DK02772604.1T
Other languages
English (en)
Inventor
Miles Carroll
Abigail Lamikanra
Alan Kingsman
Original Assignee
Oxford Biomedica Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxford Biomedica Ltd filed Critical Oxford Biomedica Ltd
Application granted granted Critical
Publication of DK1440152T3 publication Critical patent/DK1440152T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77Internalization into the cell
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
DK02772604.1T 2001-11-02 2002-11-04 5t4-ligand DK1440152T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0126378.9A GB0126378D0 (en) 2001-11-02 2001-11-02 Antigen
PCT/GB2002/004965 WO2003038098A2 (en) 2001-11-02 2002-11-04 5t4 ligand

Publications (1)

Publication Number Publication Date
DK1440152T3 true DK1440152T3 (da) 2013-07-29

Family

ID=9925057

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02772604.1T DK1440152T3 (da) 2001-11-02 2002-11-04 5t4-ligand

Country Status (6)

Country Link
US (4) US20050175618A1 (da)
EP (1) EP1440152B1 (da)
DK (1) DK1440152T3 (da)
ES (1) ES2430968T3 (da)
GB (1) GB0126378D0 (da)
WO (1) WO2003038098A2 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136311A (en) 1996-05-06 2000-10-24 Cornell Research Foundation, Inc. Treatment and diagnosis of cancer
MXPA05001933A (es) * 2002-08-19 2005-04-28 Genentech Inc Composiciones y metodos para el diagnostico y tratamiento de tumores.
BRPI0515113A (pt) * 2004-09-10 2008-07-01 Wyeth Corp anticorpos anti-5t4 humanizados e conjugados de anticorpo anti-5t4/caliqueamicina
ES2712942T3 (es) * 2006-03-10 2019-05-16 Wyeth Llc Anticuerpos anti-5T4 y usos de los mismos
AU2013216628C1 (en) * 2006-03-10 2016-02-04 Wyeth Llc Anti-5t4 antibodies and uses thereof
ES2712732T3 (es) 2009-02-17 2019-05-14 Cornell Res Foundation Inc Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
RU2673908C2 (ru) 2009-12-02 2018-12-03 Имэджинэб, Инк. Мини-антитела j591 и цис-диатела для направленной доставки простата-специфичного мембранного антигена (psma) человека и способы их применения
US10254286B2 (en) 2012-01-24 2019-04-09 Pfizer Inc. Methods for detecting 5T4-positive circulating tumor cells and methods of diagnosis of 5T4-positive cancer in a mammalian subject
PE20161413A1 (es) 2013-11-04 2017-01-10 Stemcentrx Inc Conjugados de anticuerpo anti-efna4-farmaco
WO2015155345A1 (en) * 2014-04-11 2015-10-15 Medimmune Limited Antibodies and antibody-drug conjugates
BR112016027912A2 (pt) 2014-05-29 2018-02-20 Macrogenics, Inc. molécula de ligação triespecífica capaz de se ligar de maneira imunoespecífica a três epítopos diferentes, composição farmacêutica, método de tratamento de câncer, método de tratamento de uma doença associada à presença de um patógeno, anticorpo anti-ror1, ou fragmento de ligação a ror1, fragmento de anticorpo biespecífico, bite ou anticorpo de cadeia simples, e método de tratamento de câncer
US10680464B2 (en) * 2014-09-02 2020-06-09 Panasonic Intellectual Property Management Co., Ltd. Contactless power receiver, contactless power feeder, and contactless power transmission system provided with same
CA2994951A1 (en) 2015-08-07 2017-02-16 Imaginab, Inc. Antigen binding constructs to target molecules
BR112018010394A8 (pt) * 2015-11-24 2019-02-26 Synthon Biopharmaceuticals Bv anticorpo, conjugado anticorpo-fármaco, composição farmacêutica, e, combinação do anticorpo.
CN110606890B (zh) * 2015-12-24 2021-11-26 凯惠科技发展(上海)有限公司 一种tpbg抗体及其制备方法、其偶联物和应用
WO2018147960A1 (en) 2017-02-08 2018-08-16 Imaginab, Inc. Extension sequences for diabodies
CN110678197A (zh) * 2017-03-15 2020-01-10 牛津生物医学(英国)有限公司 方法
PE20210339A1 (es) 2018-03-12 2021-02-22 Genmab As Anticuerpos
EP4028424A1 (en) 2019-09-12 2022-07-20 Genmab A/S Bispecific antibodies binding to 5t4 and cd3 for use in treatment of cancer

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US239400A (en) 1881-03-29 Tobacco-fork
NL181407B (nl) * 1952-09-20 Merck & Co Inc Verbetering van een werkwijze ter bereiding van een farmaceutisch preparaat met antibacteriele werking, dat een combinatie van een verbinding van het 3-fluor-d-alaninetype en een cycloserineverbinding bevat.
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
IL74497A (en) * 1985-03-05 1990-02-09 Proterra Ag Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives
GB8607679D0 (en) 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US4997913A (en) * 1986-06-30 1991-03-05 Oncogen pH-sensitive immunoconjugates and methods for their use in tumor therapy
WO1988009344A1 (en) 1987-05-21 1988-12-01 Creative Biomolecules, Inc. Targeted multifunctional proteins
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
AU3353989A (en) 1988-03-04 1989-09-22 Cancer Research Campaign Technology Limited Improvements relating to antigens
US5591624A (en) * 1988-03-21 1997-01-07 Chiron Viagene, Inc. Retroviral packaging cell lines
WO1990002809A1 (en) 1988-09-02 1990-03-22 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
AU634186B2 (en) 1988-11-11 1993-02-18 Medical Research Council Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors
JP2501886B2 (ja) 1988-11-16 1996-05-29 日産自動車株式会社 車体組み立て方法
US5750542A (en) * 1993-09-28 1998-05-12 Pfizer Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors
EP0621338A3 (en) * 1993-04-21 1997-10-29 Ajinomoto Kk The interleukin-2 response blocking immunosuppressor.
GB9324807D0 (en) * 1993-12-03 1994-01-19 Cancer Res Campaign Tech Tumour antibody
US5559099A (en) * 1994-09-08 1996-09-24 Genvec, Inc. Penton base protein and methods of using same
ATE208633T1 (de) * 1994-09-16 2001-11-15 Merck Patent Gmbh Immunokonjugate
WO1997014809A2 (en) * 1995-10-16 1997-04-24 Dana-Farber Cancer Institute Novel expression vectors and methods of use
SE9601245D0 (sv) * 1996-03-29 1996-03-29 Pharmacia Ab Chimeric superantigens and their use
US5998423A (en) * 1996-10-08 1999-12-07 Therasys, Inc. Methods for modulating melanin production
US6348584B1 (en) * 1996-10-17 2002-02-19 John Edward Hodgson Fibronectin binding protein compounds
EP1012259B1 (en) * 1997-06-04 2009-09-30 Oxford Biomedica (UK) Limited Tumor targeted vector
AU756452B2 (en) * 1998-08-10 2003-01-16 Agensys, Inc. BPC-1: a secreted brain specific protein expressed and secreted by prostate and bladder cancer cells
EP1160323A1 (en) 1998-11-18 2001-12-05 Oxford Biomedica (UK) Limited 5T4 tumour-associated antigen for use in tumour immunotherapy
AU1290001A (en) * 1999-11-18 2001-05-30 Oxford Biomedica (Uk) Limited Antibodies
ATE411342T1 (de) * 1999-11-18 2008-10-15 Oxford Biomedica Ltd Scfv antikörper gegen krankheiten-assoziierte moleküle
SE0102327D0 (sv) * 2001-06-28 2001-06-28 Active Biotech Ab A novel engineered superantigen for human therapy
US6875425B2 (en) * 2002-12-12 2005-04-05 Unilever Home & Personal Care Usa Skin lightening agents, compositions and methods
US7247294B1 (en) * 2006-03-30 2007-07-24 Conopco, Inc. Skin lightening agents, compositions and methods
US7270805B1 (en) * 2006-03-30 2007-09-18 Conopco, Inc. Skin lightening agents, compositions and methods
US7250158B1 (en) * 2006-03-30 2007-07-31 Conopco, Inc. Skin lightening agents, compositions and methods

Also Published As

Publication number Publication date
WO2003038098A3 (en) 2003-06-12
GB0126378D0 (en) 2002-01-02
ES2430968T3 (es) 2013-11-22
EP1440152B1 (en) 2013-04-24
WO2003038098A2 (en) 2003-05-08
US20130236479A1 (en) 2013-09-12
US20100310584A1 (en) 2010-12-09
US20090155290A1 (en) 2009-06-18
US20050175618A1 (en) 2005-08-11
EP1440152A2 (en) 2004-07-28

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