DK1440152T3 - 5t4-ligand - Google Patents
5t4-ligandInfo
- Publication number
- DK1440152T3 DK1440152T3 DK02772604.1T DK02772604T DK1440152T3 DK 1440152 T3 DK1440152 T3 DK 1440152T3 DK 02772604 T DK02772604 T DK 02772604T DK 1440152 T3 DK1440152 T3 DK 1440152T3
- Authority
- DK
- Denmark
- Prior art keywords
- ligand
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0126378.9A GB0126378D0 (en) | 2001-11-02 | 2001-11-02 | Antigen |
PCT/GB2002/004965 WO2003038098A2 (en) | 2001-11-02 | 2002-11-04 | 5t4 ligand |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1440152T3 true DK1440152T3 (da) | 2013-07-29 |
Family
ID=9925057
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK02772604.1T DK1440152T3 (da) | 2001-11-02 | 2002-11-04 | 5t4-ligand |
Country Status (6)
Country | Link |
---|---|
US (4) | US20050175618A1 (da) |
EP (1) | EP1440152B1 (da) |
DK (1) | DK1440152T3 (da) |
ES (1) | ES2430968T3 (da) |
GB (1) | GB0126378D0 (da) |
WO (1) | WO2003038098A2 (da) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6136311A (en) | 1996-05-06 | 2000-10-24 | Cornell Research Foundation, Inc. | Treatment and diagnosis of cancer |
JP2006510735A (ja) * | 2002-08-19 | 2006-03-30 | ジェネンテック・インコーポレーテッド | 腫瘍の診断と治療のための組成物と方法 |
WO2006031653A2 (en) * | 2004-09-10 | 2006-03-23 | Wyeth | Humanized anti-5t4 antibodies and anti-5t4 antibody / calicheamicin conjugates |
MX2008011492A (es) * | 2006-03-10 | 2008-09-22 | Wyeth Corp | Anticuerpos anti-5t4 y usos de los mismos. |
AU2013216628C1 (en) * | 2006-03-10 | 2016-02-04 | Wyeth Llc | Anti-5t4 antibodies and uses thereof |
JP5906090B2 (ja) | 2009-02-17 | 2016-04-20 | コーネル・リサーチ・ファンデーション・インコーポレイテッドCornell Research Foundation, Incorporated | 癌の診断のための方法およびキットならびに治療価の推定 |
CA2782333C (en) | 2009-12-02 | 2019-06-04 | Imaginab, Inc. | J591 minibodies and cys-diabodies for targeting human prostate specific membrane antigen (psma) and methods for their use |
JP6254951B2 (ja) | 2012-01-24 | 2017-12-27 | ファイザー・インク | 哺乳類の対象における5t4陽性循環腫瘍細胞を検出するための方法および5t4陽性がんの診断の方法 |
WO2015065954A1 (en) | 2013-11-04 | 2015-05-07 | Pfizer, Inc. | Anti-efna4 antibody-drug conjugates |
WO2015155345A1 (en) * | 2014-04-11 | 2015-10-15 | Medimmune Limited | Antibodies and antibody-drug conjugates |
RU2718692C2 (ru) * | 2014-05-29 | 2020-04-13 | Мэкроудженикс, Инк. | Триспецифичные связывающие молекулы, которые специфически связывают антигены множества злокачественных опухолей, и способы их применения |
US10680464B2 (en) * | 2014-09-02 | 2020-06-09 | Panasonic Intellectual Property Management Co., Ltd. | Contactless power receiver, contactless power feeder, and contactless power transmission system provided with same |
EP4137158A1 (en) | 2015-08-07 | 2023-02-22 | Imaginab, Inc. | Antigen binding constructs to target molecules |
JP6914956B2 (ja) * | 2015-11-24 | 2021-08-04 | ビョンディス・ビー.ブイ.Byondis B.V. | 抗5t4抗体および抗体−薬物コンジュゲート |
CN110698560B (zh) * | 2015-12-24 | 2021-11-26 | 凯惠科技发展(上海)有限公司 | 一种tpbg抗体及其制备方法、其偶联物和应用 |
US11266745B2 (en) | 2017-02-08 | 2022-03-08 | Imaginab, Inc. | Extension sequences for diabodies |
KR102609624B1 (ko) * | 2017-03-15 | 2023-12-05 | 옥스포드 바이오메디카(유케이) 리미티드 | 방법 |
MX2020009379A (es) | 2018-03-12 | 2020-10-14 | Genmab As | Anticuerpos. |
EP4028424A1 (en) | 2019-09-12 | 2022-07-20 | Genmab A/S | Bispecific antibodies binding to 5t4 and cd3 for use in treatment of cancer |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US239400A (en) | 1881-03-29 | Tobacco-fork | ||
NL181407B (nl) * | 1952-09-20 | Merck & Co Inc | Verbetering van een werkwijze ter bereiding van een farmaceutisch preparaat met antibacteriele werking, dat een combinatie van een verbinding van het 3-fluor-d-alaninetype en een cycloserineverbinding bevat. | |
US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
IL74497A (en) * | 1985-03-05 | 1990-02-09 | Proterra Ag | Pharmaceutical compositions containing phenyl carbamate derivatives and certain phenyl carbamate derivatives |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
US4997913A (en) * | 1986-06-30 | 1991-03-05 | Oncogen | pH-sensitive immunoconjugates and methods for their use in tumor therapy |
DE3856559T2 (de) | 1987-05-21 | 2004-04-29 | Micromet Ag | Multifunktionelle Proteine mit vorbestimmter Zielsetzung |
FI95572C (fi) * | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
AU3353989A (en) | 1988-03-04 | 1989-09-22 | Cancer Research Campaign Technology Limited | Improvements relating to antigens |
US5591624A (en) * | 1988-03-21 | 1997-01-07 | Chiron Viagene, Inc. | Retroviral packaging cell lines |
DE68927933T2 (de) | 1988-09-02 | 1997-08-14 | Dyax Corp | Herstellung und auswahl von rekombinantproteinen mit verschiedenen bindestellen |
WO1990005144A1 (en) | 1988-11-11 | 1990-05-17 | Medical Research Council | Single domain ligands, receptors comprising said ligands, methods for their production, and use of said ligands and receptors |
JP2501886B2 (ja) | 1988-11-16 | 1996-05-29 | 日産自動車株式会社 | 車体組み立て方法 |
US5750542A (en) * | 1993-09-28 | 1998-05-12 | Pfizer | Benzisoxazole and benzisothizole derivatives as cholinesterase inhibitors |
US5582826A (en) * | 1993-04-21 | 1996-12-10 | Ajinomoto Co., Inc. | Monoclonal antibodies which bind the gamma chain of human interleukin-2 receptor |
GB9324807D0 (en) * | 1993-12-03 | 1994-01-19 | Cancer Res Campaign Tech | Tumour antibody |
US5559099A (en) * | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
DE69523857T2 (de) * | 1994-09-16 | 2002-06-13 | Merck Patent Gmbh | Immunokonjugate |
CA2234931C (en) * | 1995-10-16 | 2010-01-19 | Dana-Farber Cancer Institute | Novel expression vectors and methods of use |
SE9601245D0 (sv) * | 1996-03-29 | 1996-03-29 | Pharmacia Ab | Chimeric superantigens and their use |
US5998423A (en) * | 1996-10-08 | 1999-12-07 | Therasys, Inc. | Methods for modulating melanin production |
US6348584B1 (en) * | 1996-10-17 | 2002-02-19 | John Edward Hodgson | Fibronectin binding protein compounds |
EP1717248A1 (en) * | 1997-06-04 | 2006-11-02 | Oxford Biomedica (UK) Limited | Tumor targeted vector |
ATE350474T1 (de) * | 1998-08-10 | 2007-01-15 | Agensys Inc | Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird |
JP4907767B2 (ja) | 1998-11-18 | 2012-04-04 | オックスフォード バイオメディカ(ユーケー)リミテッド | ポリペプチド |
DE60040555D1 (de) * | 1999-11-18 | 2008-11-27 | Oxford Biomedica Ltd | Küle |
JP2003515323A (ja) * | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ(ユーケイ)リミテッド | 抗 体 |
SE0102327D0 (sv) * | 2001-06-28 | 2001-06-28 | Active Biotech Ab | A novel engineered superantigen for human therapy |
US6875425B2 (en) * | 2002-12-12 | 2005-04-05 | Unilever Home & Personal Care Usa | Skin lightening agents, compositions and methods |
US7270805B1 (en) * | 2006-03-30 | 2007-09-18 | Conopco, Inc. | Skin lightening agents, compositions and methods |
US7250158B1 (en) * | 2006-03-30 | 2007-07-31 | Conopco, Inc. | Skin lightening agents, compositions and methods |
US7247294B1 (en) * | 2006-03-30 | 2007-07-24 | Conopco, Inc. | Skin lightening agents, compositions and methods |
-
2001
- 2001-11-02 GB GBGB0126378.9A patent/GB0126378D0/en not_active Ceased
-
2002
- 2002-11-04 WO PCT/GB2002/004965 patent/WO2003038098A2/en not_active Application Discontinuation
- 2002-11-04 ES ES02772604T patent/ES2430968T3/es not_active Expired - Lifetime
- 2002-11-04 DK DK02772604.1T patent/DK1440152T3/da active
- 2002-11-04 US US10/493,627 patent/US20050175618A1/en not_active Abandoned
- 2002-11-04 EP EP02772604.1A patent/EP1440152B1/en not_active Expired - Lifetime
-
2008
- 2008-12-10 US US12/332,022 patent/US20090155290A1/en not_active Abandoned
-
2009
- 2009-10-21 US US12/603,282 patent/US20100310584A1/en not_active Abandoned
-
2013
- 2013-04-19 US US13/866,321 patent/US20130236479A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20050175618A1 (en) | 2005-08-11 |
US20130236479A1 (en) | 2013-09-12 |
US20100310584A1 (en) | 2010-12-09 |
US20090155290A1 (en) | 2009-06-18 |
WO2003038098A3 (en) | 2003-06-12 |
ES2430968T3 (es) | 2013-11-22 |
EP1440152B1 (en) | 2013-04-24 |
GB0126378D0 (en) | 2002-01-02 |
EP1440152A2 (en) | 2004-07-28 |
WO2003038098A2 (en) | 2003-05-08 |
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