DK1438437T3 - Fremgangsmåde til påvisning af cytosin-methyleringer i immobiliserede DNA-pröver - Google Patents

Fremgangsmåde til påvisning af cytosin-methyleringer i immobiliserede DNA-pröver

Info

Publication number
DK1438437T3
DK1438437T3 DK02802274T DK02802274T DK1438437T3 DK 1438437 T3 DK1438437 T3 DK 1438437T3 DK 02802274 T DK02802274 T DK 02802274T DK 02802274 T DK02802274 T DK 02802274T DK 1438437 T3 DK1438437 T3 DK 1438437T3
Authority
DK
Denmark
Prior art keywords
dna
immobilized
dna samples
immobilized dna
analyzing
Prior art date
Application number
DK02802274T
Other languages
Danish (da)
English (en)
Inventor
Matthias Ballhause
Kurt Berlin
David Guetig
Original Assignee
Epigenomics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epigenomics Ag filed Critical Epigenomics Ag
Application granted granted Critical
Publication of DK1438437T3 publication Critical patent/DK1438437T3/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK02802274T 2001-10-26 2002-10-25 Fremgangsmåde til påvisning af cytosin-methyleringer i immobiliserede DNA-pröver DK1438437T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10154317A DE10154317B4 (de) 2001-10-26 2001-10-26 Verfahren zum Nachweis von Cytosin-Methylierungen in immobilisierten DNA Proben
PCT/DE2002/004054 WO2003038121A2 (de) 2001-10-26 2002-10-25 Verfahren zum nachweis von cytosin-methylierungen in immobilisierten dna proben

Publications (1)

Publication Number Publication Date
DK1438437T3 true DK1438437T3 (da) 2009-07-20

Family

ID=7704694

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02802274T DK1438437T3 (da) 2001-10-26 2002-10-25 Fremgangsmåde til påvisning af cytosin-methyleringer i immobiliserede DNA-pröver

Country Status (10)

Country Link
US (3) US7407749B2 (ja)
EP (2) EP2085487A1 (ja)
JP (1) JP2005506850A (ja)
AT (1) ATE429512T1 (ja)
AU (1) AU2002363259B2 (ja)
CA (1) CA2462932C (ja)
DE (2) DE10154317B4 (ja)
DK (1) DK1438437T3 (ja)
ES (1) ES2325121T3 (ja)
WO (1) WO2003038121A2 (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060134643A1 (en) 2000-06-19 2006-06-22 Kurt Berlin Bisulfite conversion of DNA
US20110151438A9 (en) 2001-11-19 2011-06-23 Affymetrix, Inc. Methods of Analysis of Methylation
AU2003236461B2 (en) * 2002-08-29 2009-05-28 Epigenomics Ag Improved method for bisulfite treatment
DE10338308B4 (de) 2003-08-15 2006-10-19 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungen in DNA
WO2005024068A2 (en) 2003-09-05 2005-03-17 Sequenom, Inc. Allele-specific sequence variation analysis
ATE431856T1 (de) * 2003-10-09 2009-06-15 Epigenomics Ag Verbesserte bisulfitkonversion von dna
AU2005230936B2 (en) 2004-03-26 2010-08-05 Agena Bioscience, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
ES2668911T3 (es) * 2004-09-30 2018-05-23 Epigenomics Ag Método para proveer fragmentos de ADN derivados de una muestra archivada
WO2006084340A1 (en) * 2005-02-14 2006-08-17 Commonwealth Scientific And Industrial Research Organisation Solid phase assay for methylation analysis
US8129107B2 (en) 2005-04-01 2012-03-06 Epigenomics Ag Bisulfite conversion of DNA
US20060223070A1 (en) * 2005-04-01 2006-10-05 Wisniewski Michele E Methods, compositions, and kits for detecting nucleic acids in a single vessel
US20060223071A1 (en) * 2005-04-01 2006-10-05 Wisniewski Michele E Methods, compositions, and kits for detecting nucleic acids in a single vessel
US20060292585A1 (en) * 2005-06-24 2006-12-28 Affymetrix, Inc. Analysis of methylation using nucleic acid arrays
EP1746169B1 (de) 2005-07-21 2009-12-23 Epigenomics AG Verfahren zur Quantifizierung methylierter DNA
US7901882B2 (en) 2006-03-31 2011-03-08 Affymetrix, Inc. Analysis of methylation using nucleic acid arrays
DE102006046776B4 (de) * 2006-09-29 2019-07-18 Siemens Aktiengesellschaft Anordnung und Verfahren zum Nachweis kleiner Stoffkonzentrationen
US20080213870A1 (en) * 2007-03-01 2008-09-04 Sean Wuxiong Cao Methods for obtaining modified DNA from a biological specimen
EP3497220A4 (en) 2016-08-10 2020-04-01 Grail, Inc. METHOD FOR PRODUCING DUAL-INDEXED DNA LIBRARIES FOR BISULFIT CONVERSION SEQUENCING

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE501439C2 (sv) 1993-06-22 1995-02-13 Pharmacia Lkb Biotech Sätt och anordning för analys av polynukleotidsekvenser
ATE203171T1 (de) 1993-08-10 2001-08-15 Slobodan Tepic Gerät zum behandeln von tumoren mittels selektiver proteinverringerung
DE69417918T2 (de) 1993-11-30 2000-01-05 Mcgill University, Montreal Dna methyltransferase inhibierung
JPH11514872A (ja) 1995-10-18 1999-12-21 ダーウィン モレキュラー コーポレイション ハイブリダイゼーション用の固体支持体を調製する方法および非特異的バックグラウンドを低減する方法
US6017704A (en) 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
DE69836587T2 (de) * 1997-04-16 2007-10-11 Applera Corp., Foster City Nukleinsäuresammlung
DE19746874A1 (de) * 1997-10-23 1999-04-29 Qiagen Gmbh Verfahren zur Isolierung und Reinigung von Nukleinsäuren an hydrophoben Oberflächen - insbesondere unter Verwendung hydrophober Membranen
DE19754482A1 (de) 1997-11-27 1999-07-01 Epigenomics Gmbh Verfahren zur Herstellung komplexer DNA-Methylierungs-Fingerabdrücke
DE19905082C1 (de) * 1999-01-29 2000-05-18 Epigenomics Gmbh Verfahren zur Identifikation von Cytosin-Methylierungsmustern in genomischen DNA-Proben
US6331393B1 (en) 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
US20020055184A1 (en) * 1999-09-08 2002-05-09 Stephen Naylor Systems for detecting analytes
DE10029915B4 (de) * 2000-06-19 2005-06-16 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungen
US20040054162A1 (en) * 2001-10-30 2004-03-18 Hanna Michelle M. Molecular detection systems utilizing reiterative oligonucleotide synthesis
AU2003236461B2 (en) * 2002-08-29 2009-05-28 Epigenomics Ag Improved method for bisulfite treatment
US7371526B2 (en) 2003-08-29 2008-05-13 Applera Corporation Method and materials for bisulfite conversion of cytosine to uracil
US7534873B2 (en) 2003-08-29 2009-05-19 Applied Biosystems, Llc Method and materials for quaternary amine catalyzed bisulfite conversion of cytosine to uracil
US7368239B2 (en) 2003-08-29 2008-05-06 Applera Corporation Method and materials for polyamine catalyzed bisulfite conversion of cytosine to uracil
ATE431856T1 (de) 2003-10-09 2009-06-15 Epigenomics Ag Verbesserte bisulfitkonversion von dna

Also Published As

Publication number Publication date
WO2003038121A2 (de) 2003-05-08
DE50213489D1 (de) 2009-06-04
US20090280494A1 (en) 2009-11-12
EP1438437A2 (de) 2004-07-21
DE10154317A1 (de) 2003-05-15
US7534570B2 (en) 2009-05-19
EP2085487A1 (de) 2009-08-05
US20040115663A1 (en) 2004-06-17
US20080113379A1 (en) 2008-05-15
ATE429512T1 (de) 2009-05-15
AU2002363259B2 (en) 2007-09-06
ES2325121T3 (es) 2009-08-26
CA2462932A1 (en) 2003-05-08
JP2005506850A (ja) 2005-03-10
WO2003038121A3 (de) 2003-12-11
CA2462932C (en) 2011-04-26
DE10154317B4 (de) 2005-06-09
US7407749B2 (en) 2008-08-05
EP1438437B1 (de) 2009-04-22

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