DK143109C - Optisk aktiv lacton til anvendelse som mellemprodukt i syntesen af (+)-biotin og fremgangsmaade til fremstilling af den optisk aktive lacton - Google Patents

Optisk aktiv lacton til anvendelse som mellemprodukt i syntesen af (+)-biotin og fremgangsmaade til fremstilling af den optisk aktive lacton

Info

Publication number
DK143109C
DK143109C DK607170A DK607170A DK143109C DK 143109 C DK143109 C DK 143109C DK 607170 A DK607170 A DK 607170A DK 607170 A DK607170 A DK 607170A DK 143109 C DK143109 C DK 143109C
Authority
DK
Denmark
Prior art keywords
lacton
active
biotin
synthesis
procedure
Prior art date
Application number
DK607170A
Other languages
Danish (da)
English (en)
Other versions
DK143109B (da
Inventor
M Gerecke
J P Zimmermann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK143109B publication Critical patent/DK143109B/da
Application granted granted Critical
Publication of DK143109C publication Critical patent/DK143109C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK607170A 1969-11-29 1970-11-27 Optisk aktiv lacton til anvendelse som mellemprodukt i syntesen af (+)-biotin og fremgangsmaade til fremstilling af den optisk aktive lacton DK143109C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1777269A CH565798A5 (xx) 1969-11-29 1969-11-29
CH1777269 1969-11-29

Publications (2)

Publication Number Publication Date
DK143109B DK143109B (da) 1981-03-30
DK143109C true DK143109C (da) 1981-09-21

Family

ID=4427992

Family Applications (1)

Application Number Title Priority Date Filing Date
DK607170A DK143109C (da) 1969-11-29 1970-11-27 Optisk aktiv lacton til anvendelse som mellemprodukt i syntesen af (+)-biotin og fremgangsmaade til fremstilling af den optisk aktive lacton

Country Status (10)

Country Link
JP (1) JPS4932551B1 (xx)
BE (1) BE759512A (xx)
CA (1) CA983938A (xx)
CH (1) CH565798A5 (xx)
DE (1) DE2058248C3 (xx)
DK (1) DK143109C (xx)
FR (1) FR2077539B1 (xx)
GB (1) GB1287839A (xx)
NL (1) NL159385B (xx)
SE (1) SE391718B (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0081047B1 (de) * 1981-12-07 1985-12-18 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung eines optisch aktiven Lactons und neue Ausgangsprodukte in diesem Verfahren
DE3150723A1 (de) * 1981-12-22 1983-06-30 Basf Ag, 6700 Ludwigshafen Verbessertes verfahren zur herstellung von 1,3-disubstituierten 4,5-cis-dicarboxy-2-imidazolidonen
CH670644A5 (xx) * 1986-12-18 1989-06-30 Lonza Ag
CH671227A5 (xx) * 1986-12-02 1989-08-15 Lonza Ag
US5162540A (en) * 1986-12-18 1992-11-10 Lonza Ltd. Process for the production of (+) biotin
FI95034C (fi) * 1989-03-15 1995-12-11 Lonza Ag Menetelmä 1,3-substituoidun tetrahydro-1H-tieno/3,4-d/-imidatsol-2(3H)-on-4-ylideenipentaanihappoesterin valmistamiseksi
FI935609A (fi) * 1992-12-18 1994-06-19 Lonza Ag Dihydrofuroimidatsolijohdannaisten asymmetrinen hydraus
CA2134441A1 (en) * 1993-04-20 1994-10-27 Martin Eyer Asymmetric hydrogenation of furoimidazole derivatives
CA2122511A1 (en) * 1993-05-14 1994-11-15 John Mcgarrity Asymmetric hydrogenation of furoimidazole derivatives
DE10033284A1 (de) * 2000-07-07 2002-01-17 Merck Patent Gmbh Verfahren zur Herstellung von (+)-Biotin
TW200300676A (en) 2001-12-04 2003-06-16 Tanabe Seiyaku Co Biotin intermediate and its production
CN113121549B (zh) * 2019-12-31 2022-08-26 江西天新药业股份有限公司 立体选择性合成手性内酯的方法和手性化合物及其应用

Also Published As

Publication number Publication date
CH565798A5 (xx) 1975-08-29
CA983938A (en) 1976-02-17
NL7015355A (xx) 1971-06-02
DE2058248C3 (de) 1980-12-18
JPS4932551B1 (xx) 1974-08-31
FR2077539A1 (xx) 1971-10-29
DK143109B (da) 1981-03-30
GB1287839A (xx) 1972-09-06
FR2077539B1 (xx) 1973-02-02
BE759512A (fr) 1971-05-27
NL159385B (nl) 1979-02-15
DE2058248B2 (de) 1980-04-10
DE2058248A1 (de) 1971-06-09
SE391718B (sv) 1977-02-28

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Legal Events

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PUP Patent expired