DK1428816T3 - Fremgangsmåde til fremstilling af dodecyl-2-(N,N-dimethylamino)-propionat - Google Patents
Fremgangsmåde til fremstilling af dodecyl-2-(N,N-dimethylamino)-propionatInfo
- Publication number
- DK1428816T3 DK1428816T3 DK04006144.2T DK04006144T DK1428816T3 DK 1428816 T3 DK1428816 T3 DK 1428816T3 DK 04006144 T DK04006144 T DK 04006144T DK 1428816 T3 DK1428816 T3 DK 1428816T3
- Authority
- DK
- Denmark
- Prior art keywords
- dimethylamino
- propionate
- dodecyl
- preparation
- ddaip
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
- C07C227/42—Crystallisation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
- C07C229/12—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of acyclic carbon skeletons
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
- Paper (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Holo Graphy (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/314,571 US6118020A (en) | 1999-05-19 | 1999-05-19 | Crystalline salts of dodecyl 2-(N,N-dimethylamino)-propionate |
| EP00932524A EP1097126B1 (en) | 1999-05-19 | 2000-05-18 | Crystalline salts of dodecyl 2-(n,n-dimethylamino)-propionate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1428816T3 true DK1428816T3 (da) | 2012-10-01 |
Family
ID=23220476
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00932524T DK1097126T3 (da) | 1999-05-19 | 2000-05-18 | Krystallinske salte af dodecyl-2-(N,N-dimethylamino)-propionat |
| DK04006144.2T DK1428816T3 (da) | 1999-05-19 | 2000-05-18 | Fremgangsmåde til fremstilling af dodecyl-2-(N,N-dimethylamino)-propionat |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK00932524T DK1097126T3 (da) | 1999-05-19 | 2000-05-18 | Krystallinske salte af dodecyl-2-(N,N-dimethylamino)-propionat |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US6118020A (da) |
| EP (2) | EP1097126B1 (da) |
| JP (1) | JP4864208B2 (da) |
| KR (1) | KR100688920B1 (da) |
| CN (3) | CN1244546C (da) |
| AT (1) | ATE272607T1 (da) |
| AU (1) | AU781427B2 (da) |
| BR (1) | BR0006133A (da) |
| CA (2) | CA2338139C (da) |
| CY (1) | CY1113331T1 (da) |
| DE (1) | DE60012656T2 (da) |
| DK (2) | DK1097126T3 (da) |
| ES (2) | ES2223524T3 (da) |
| HK (2) | HK1088592A1 (da) |
| HU (1) | HU230508B1 (da) |
| IL (1) | IL140569A (da) |
| MX (1) | MXPA01000669A (da) |
| PT (2) | PT1097126E (da) |
| SI (1) | SI1097126T1 (da) |
| TW (1) | TWI256949B (da) |
| WO (1) | WO2000069809A1 (da) |
| ZA (1) | ZA200100142B (da) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6414028B1 (en) * | 1997-11-05 | 2002-07-02 | Nexmed Holdings, Inc. | Topical compositions containing prostaglandin E1 |
| IL142535A0 (en) * | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Pharmaceutical compositions for the treatment of inflammation |
| IL142536A0 (en) * | 2001-04-11 | 2002-03-10 | Yeda Res & Dev | Carriers for therapeutic preparations for treatment of t-cell mediated diseases |
| WO2004032824A2 (en) | 2002-10-10 | 2004-04-22 | Yeda Research And Development Co. Ltd. | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents |
| MXPA05010068A (es) * | 2003-03-21 | 2005-11-23 | Nexmed Holdings Inc | Promocion de la angiogenesis por composiciones de prostaglandina y metodos. |
| EP1635770B1 (en) | 2003-03-21 | 2009-05-27 | Nexmed Holdings, Inc. | Antifungal nail coat and method of use |
| CA2519707A1 (en) * | 2003-03-21 | 2004-10-07 | Nexmed (Holdings), Inc. | Prostaglandin compositions for the treatment of erectile dysfunction |
| CN1777429A (zh) | 2003-04-02 | 2006-05-24 | 尼克美制药控股有限公司 | 前列腺素组合物和其治疗血管痉挛的应用 |
| WO2008106092A1 (en) * | 2007-02-26 | 2008-09-04 | Yeda Research And Development Co. Ltd. | Enantiomers of amino-phenyl-acetic acid octadec- 9- (z) enyl ester, their salts and their uses |
| EP2117301A4 (en) * | 2007-02-26 | 2010-04-14 | Yeda Res & Dev | USE OF LONG-CHAINED ALCOHOL DERIVATIVES FOR THE TREATMENT OF CIRCULAR HAIR LOSS |
| EP2451944A4 (en) | 2009-07-10 | 2012-11-28 | Harvard College | Permanently loaded soda and calcium channel blockers as anti-inflammatory agents |
| ES2677352T3 (es) * | 2009-12-18 | 2018-08-01 | Achelios Therapeutics, Inc. | Métodos y composiciones para tratar y prevenir las cefaleas autonómicas trigeminales, la migraña y las afecciones vasculares |
| MX336037B (es) * | 2010-05-04 | 2016-01-07 | Nexmed Holdings Inc | Composicion y metodo de peptido terapeutico. |
| CN102858158A (zh) * | 2010-05-04 | 2013-01-02 | 尼克美控股公司 | 小分子治疗剂的组合物 |
| SG188612A1 (en) * | 2010-09-24 | 2013-04-30 | Nexmed Holdings Inc | Enhanced transbuccal drug delivery system and compositions |
| MX2013005522A (es) | 2010-12-02 | 2013-07-17 | Nexmed Holdings Inc | Enantiomero activo de dodecil-2-(n,n-dimetilamino)-propionato. |
| WO2012097160A1 (en) * | 2011-01-14 | 2012-07-19 | Nexmed Holdings, Inc. | Rectal delivery method for therapeutic peptides |
| EP2693877A4 (en) | 2011-04-07 | 2014-11-19 | Nexmed Holdings Inc | METHODS AND COMPOSITIONS FOR TREATING RAYNAUD'S DISEASE |
| US8900625B2 (en) * | 2012-12-15 | 2014-12-02 | Nexmed Holdings, Inc. | Antimicrobial compounds and methods of use |
| EP2934497B1 (en) | 2012-12-21 | 2016-11-23 | Teikoku Pharma USA, Inc. | Compositions and methods for transdermal delivery of hormones and other medicinal agents |
| WO2016089893A1 (en) | 2014-12-01 | 2016-06-09 | Achelios Therapeutics Inc. | Methods and compositions for treating migraine and conditions associated with pain |
| RU2018107695A (ru) | 2015-08-03 | 2019-09-05 | Президент Энд Феллоуз Оф Гарвард Колледж | Заряженные блокаторы ионных каналов и способы их применения |
| JP2019532027A (ja) | 2016-08-17 | 2019-11-07 | ソルスティス バイオロジクス，リミティッド | ポリヌクレオチド構築物 |
| US11597744B2 (en) | 2017-06-30 | 2023-03-07 | Sirius Therapeutics, Inc. | Chiral phosphoramidite auxiliaries and methods of their use |
| MA55318A (fr) | 2019-03-11 | 2022-01-19 | Nocion Therapeutics Inc | Bloqueurs de canaux ioniques chargés et procédés d'utilisation |
| JP2022527731A (ja) | 2019-03-11 | 2022-06-06 | ノシオン セラピューティクス，インコーポレイテッド | エステル置換イオンチャンネル遮断薬および使用方法 |
| US11377422B2 (en) | 2019-03-11 | 2022-07-05 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10780083B1 (en) | 2019-03-11 | 2020-09-22 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| US10828287B2 (en) | 2019-03-11 | 2020-11-10 | Nocion Therapeutics, Inc. | Charged ion channel blockers and methods for use |
| EP4054586A4 (en) | 2019-11-06 | 2023-11-22 | Nocion Therapeutics, Inc. | CHARGED ION CHANNEL BLOCKERS AND METHODS OF USE |
| IL292505A (en) | 2019-11-06 | 2022-06-01 | Nocion Therapeutics Inc | Charged ion channel blockers and methods of use |
| IL295950A (en) | 2020-03-11 | 2022-10-01 | Nocion Therapeutics Inc | Charged ion channel blockers and methods of use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4980378A (en) * | 1988-06-01 | 1990-12-25 | Odontex, Inc. | Biodegradable absorption enhancers |
| US5082866A (en) * | 1988-06-01 | 1992-01-21 | Odontex, Inc. | Biodegradable absorption enhancers |
| JPH08311210A (ja) * | 1995-05-24 | 1996-11-26 | Dai Ichi Kogyo Seiyaku Co Ltd | 樹脂成形体の導電性改良方法および静電塗装方法 |
-
1999
- 1999-05-19 US US09/314,571 patent/US6118020A/en not_active Expired - Lifetime
-
2000
- 2000-05-12 TW TW089109133A patent/TWI256949B/zh not_active IP Right Cessation
- 2000-05-18 DK DK00932524T patent/DK1097126T3/da active
- 2000-05-18 PT PT00932524T patent/PT1097126E/pt unknown
- 2000-05-18 CA CA2338139A patent/CA2338139C/en not_active Expired - Lifetime
- 2000-05-18 ES ES00932524T patent/ES2223524T3/es not_active Expired - Lifetime
- 2000-05-18 AU AU50232/00A patent/AU781427B2/en not_active Expired
- 2000-05-18 CN CNB008009139A patent/CN1244546C/zh not_active Expired - Lifetime
- 2000-05-18 CN CNA2006100513309A patent/CN1837187A/zh active Pending
- 2000-05-18 CA CA2706680A patent/CA2706680C/en not_active Expired - Lifetime
- 2000-05-18 KR KR1020017000789A patent/KR100688920B1/ko active IP Right Grant
- 2000-05-18 EP EP00932524A patent/EP1097126B1/en not_active Expired - Lifetime
- 2000-05-18 SI SI200030467T patent/SI1097126T1/xx unknown
- 2000-05-18 IL IL140569A patent/IL140569A/en not_active IP Right Cessation
- 2000-05-18 AT AT00932524T patent/ATE272607T1/de active
- 2000-05-18 BR BR0006133-6A patent/BR0006133A/pt not_active Application Discontinuation
- 2000-05-18 DK DK04006144.2T patent/DK1428816T3/da active
- 2000-05-18 JP JP2000618227A patent/JP4864208B2/ja not_active Expired - Lifetime
- 2000-05-18 DE DE60012656T patent/DE60012656T2/de not_active Expired - Lifetime
- 2000-05-18 HU HU0202090A patent/HU230508B1/hu unknown
- 2000-05-18 PT PT04006144T patent/PT1428816E/pt unknown
- 2000-05-18 EP EP04006144A patent/EP1428816B1/en not_active Expired - Lifetime
- 2000-05-18 CN CNB2005100977135A patent/CN1315783C/zh not_active Expired - Lifetime
- 2000-05-18 MX MXPA01000669A patent/MXPA01000669A/es active IP Right Grant
- 2000-05-18 ES ES04006144T patent/ES2390952T3/es not_active Expired - Lifetime
- 2000-05-18 WO PCT/US2000/013535 patent/WO2000069809A1/en active IP Right Grant
-
2001
- 2001-01-05 ZA ZA200100142A patent/ZA200100142B/en unknown
- 2001-11-29 HK HK06108943A patent/HK1088592A1/xx not_active IP Right Cessation
- 2001-11-29 HK HK01108398A patent/HK1037607A1/xx not_active IP Right Cessation
-
2012
- 2012-11-15 CY CY20121101103T patent/CY1113331T1/el unknown
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