DK1416917T3 - Vandig dispersion, der omfatter stabile nanopartikler af et vanduoplöseligt aktivt stof og en excipiens som middellangkædede triglycerider (MCT) - Google Patents

Vandig dispersion, der omfatter stabile nanopartikler af et vanduoplöseligt aktivt stof og en excipiens som middellangkædede triglycerider (MCT)

Info

Publication number
DK1416917T3
DK1416917T3 DK02745697T DK02745697T DK1416917T3 DK 1416917 T3 DK1416917 T3 DK 1416917T3 DK 02745697 T DK02745697 T DK 02745697T DK 02745697 T DK02745697 T DK 02745697T DK 1416917 T3 DK1416917 T3 DK 1416917T3
Authority
DK
Denmark
Prior art keywords
water
mct
excipient
active substance
aqueous dispersion
Prior art date
Application number
DK02745697T
Other languages
Danish (da)
English (en)
Inventor
Ulf Olsson
Tommy Urban Skantze
Per Lennart Lindfors
Corswant Lars Christian Von
Schantz Anna Elisa Zzackrisson
Pia Margaretha Cecilia Skantze
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0119081A external-priority patent/GB0119081D0/en
Priority claimed from GB0212463A external-priority patent/GB0212463D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of DK1416917T3 publication Critical patent/DK1416917T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5138—Organic macromolecular compounds; Dendrimers obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Colloid Chemistry (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Dental Preparations (AREA)
DK02745697T 2001-08-06 2002-08-01 Vandig dispersion, der omfatter stabile nanopartikler af et vanduoplöseligt aktivt stof og en excipiens som middellangkædede triglycerider (MCT) DK1416917T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0119081A GB0119081D0 (en) 2001-08-06 2001-08-06 Process
GB0212463A GB0212463D0 (en) 2002-05-30 2002-05-30 Process
PCT/GB2002/003583 WO2003013472A1 (en) 2001-08-06 2002-08-01 Aqueous dispersion comprising stable nanoparticles of a water-insoluble active and an excipient like middle chain triglycerides (mct)

Publications (1)

Publication Number Publication Date
DK1416917T3 true DK1416917T3 (da) 2007-09-17

Family

ID=26246405

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02745697T DK1416917T3 (da) 2001-08-06 2002-08-01 Vandig dispersion, der omfatter stabile nanopartikler af et vanduoplöseligt aktivt stof og en excipiens som middellangkædede triglycerider (MCT)

Country Status (19)

Country Link
US (1) US20050009908A1 (https=)
EP (1) EP1416917B1 (https=)
JP (1) JP4714412B2 (https=)
KR (1) KR100914113B1 (https=)
CN (1) CN1254233C (https=)
AT (1) ATE365537T1 (https=)
AU (1) AU2002317409B2 (https=)
BR (1) BR0211705A (https=)
CA (1) CA2456180C (https=)
CY (1) CY1107059T1 (https=)
DE (1) DE60220923T2 (https=)
DK (1) DK1416917T3 (https=)
ES (1) ES2287293T3 (https=)
IL (2) IL160103A0 (https=)
MX (1) MXPA04001071A (https=)
NO (1) NO20040484L (https=)
NZ (1) NZ530916A (https=)
PT (1) PT1416917E (https=)
WO (1) WO2003013472A1 (https=)

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GB0230088D0 (en) * 2002-12-24 2003-01-29 Astrazeneca Ab Therapeutic agents
GB0302671D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302673D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0302672D0 (en) * 2003-02-06 2003-03-12 Astrazeneca Ab Pharmaceutical formulations
GB0314057D0 (en) * 2003-06-18 2003-07-23 Astrazeneca Ab Therapeutic agents
CA2527033A1 (en) * 2003-06-18 2004-12-23 Astrazeneca Ab 2-substitued 5,6-diaryl-pyrazine derivatives as cb1 modulators
GB0314261D0 (en) * 2003-06-19 2003-07-23 Astrazeneca Ab Therapeutic agents
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US20100260691A1 (en) * 2006-07-31 2010-10-14 Narayanan Kolazi S Aqueous compositions containing a hydrophobic material
US8173686B2 (en) 2006-11-06 2012-05-08 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8178564B2 (en) * 2006-11-06 2012-05-15 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168661B2 (en) * 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US8168662B1 (en) 2006-11-06 2012-05-01 Poniard Pharmaceuticals, Inc. Use of picoplatin to treat colorectal cancer
US20110033528A1 (en) * 2009-08-05 2011-02-10 Poniard Pharmaceuticals, Inc. Stabilized picoplatin oral dosage form
US20100068287A1 (en) * 2007-02-09 2010-03-18 Astrazeneca Ab Process for Preparation of a Stable Dispersion of Solid Amorphous Submicron Particles in an Aqueous Medium
US20100260832A1 (en) * 2007-06-27 2010-10-14 Poniard Pharmaceuticals, Inc. Combination therapy for ovarian cancer
TW200916094A (en) * 2007-06-27 2009-04-16 Poniard Pharmaceuticals Inc Stabilized picoplatin dosage form
US20100310661A1 (en) * 2007-07-16 2010-12-09 Poniard Pharmaceuticals, Inc. Oral formulations for picoplatin
CA2715348A1 (en) * 2008-02-08 2009-08-13 Poniard Pharmaceuticals, Inc. Use of picoplatin and bevacizumab to treat colorectal cancer
BRPI1004808B1 (pt) * 2010-10-27 2020-09-29 Embrapa - Empresa Brasileira De Pesquisa Agropecuária Composições baseadas em nanopartículas de própolis, processos de obtenção e uso
CN107596518B (zh) 2012-02-29 2021-04-23 普马特里克斯营业公司 可吸入干粉剂
KR102045732B1 (ko) * 2012-12-28 2019-11-18 엘지디스플레이 주식회사 온도감응형 계면활성제를 이용한 수용성 나노입자의 제조방법
PT106738B (pt) 2013-01-09 2015-06-08 Hovione Farmaciencia Sa Método para o controlo do fenómeno de degradação difusional de ostwald (ostwald ripening) no processamento de partículas de um ingrediente farmacêutico
JP2016507542A (ja) * 2013-02-08 2016-03-10 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 反応型噴霧乾燥による無機／有機複合材料の製造
WO2019055525A1 (en) * 2017-09-12 2019-03-21 Raj Selvaraj FORMULATION OF SOLID NANOPARTICLES OF WATER-INSOLUBLE PHARMACEUTICAL SUBSTANCES WITH REDUCED OSTWALD CURING
MX2024005292A (es) 2021-11-05 2024-05-17 Cinclus Pharma Holding Ab Publ Polimorfos de la sal de clorhidrato de glurato de linaprazan.

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Also Published As

Publication number Publication date
EP1416917B1 (en) 2007-06-27
KR100914113B1 (ko) 2009-08-27
JP2005500362A (ja) 2005-01-06
IL160103A (en) 2008-11-26
JP4714412B2 (ja) 2011-06-29
CA2456180C (en) 2011-10-11
PT1416917E (pt) 2007-08-16
MXPA04001071A (es) 2004-05-20
CY1107059T1 (el) 2012-10-24
NO20040484L (no) 2004-03-31
BR0211705A (pt) 2004-09-28
IL160103A0 (en) 2004-06-20
ATE365537T1 (de) 2007-07-15
ES2287293T3 (es) 2007-12-16
CN1564677A (zh) 2005-01-12
CA2456180A1 (en) 2003-02-20
HK1064048A1 (en) 2005-01-21
NZ530916A (en) 2005-07-29
EP1416917A1 (en) 2004-05-12
WO2003013472A1 (en) 2003-02-20
CN1254233C (zh) 2006-05-03
KR20040025739A (ko) 2004-03-25
DE60220923D1 (de) 2007-08-09
AU2002317409B2 (en) 2007-06-21
DE60220923T2 (de) 2008-03-06
US20050009908A1 (en) 2005-01-13

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