DK141339B - Fremgangsmåde til fremstilling af felin-calicivirus vaccine. - Google Patents
Fremgangsmåde til fremstilling af felin-calicivirus vaccine. Download PDFInfo
- Publication number
- DK141339B DK141339B DK516975AA DK516975A DK141339B DK 141339 B DK141339 B DK 141339B DK 516975A A DK516975A A DK 516975AA DK 516975 A DK516975 A DK 516975A DK 141339 B DK141339 B DK 141339B
- Authority
- DK
- Denmark
- Prior art keywords
- virus
- cats
- feline
- feline calicivirus
- vaccine
- Prior art date
Links
- 241000714201 Feline calicivirus Species 0.000 title description 55
- 229960005486 vaccine Drugs 0.000 title description 34
- 238000000034 method Methods 0.000 title description 23
- 238000002360 preparation method Methods 0.000 title description 7
- 241000282326 Felis catus Species 0.000 description 53
- 241000700605 Viruses Species 0.000 description 53
- 238000012546 transfer Methods 0.000 description 35
- 241000282324 Felis Species 0.000 description 22
- 210000001519 tissue Anatomy 0.000 description 21
- 208000015181 infectious disease Diseases 0.000 description 19
- 201000010099 disease Diseases 0.000 description 18
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 18
- 210000004027 cell Anatomy 0.000 description 16
- 230000002238 attenuated effect Effects 0.000 description 14
- 210000002105 tongue Anatomy 0.000 description 13
- 238000002255 vaccination Methods 0.000 description 12
- 239000007788 liquid Substances 0.000 description 10
- 230000000120 cytopathologic effect Effects 0.000 description 8
- 238000011534 incubation Methods 0.000 description 8
- 239000011521 glass Substances 0.000 description 7
- 239000002609 medium Substances 0.000 description 7
- 231100000252 nontoxic Toxicity 0.000 description 7
- 230000003000 nontoxic effect Effects 0.000 description 7
- 208000024891 symptom Diseases 0.000 description 7
- 241001465754 Metazoa Species 0.000 description 6
- 230000005540 biological transmission Effects 0.000 description 6
- 230000015572 biosynthetic process Effects 0.000 description 5
- 230000003053 immunization Effects 0.000 description 5
- 238000011081 inoculation Methods 0.000 description 5
- 239000002054 inoculum Substances 0.000 description 5
- 230000000644 propagated effect Effects 0.000 description 5
- 210000002345 respiratory system Anatomy 0.000 description 5
- 239000003104 tissue culture media Substances 0.000 description 5
- 238000010790 dilution Methods 0.000 description 4
- 239000012895 dilution Substances 0.000 description 4
- 238000004108 freeze drying Methods 0.000 description 4
- 238000002955 isolation Methods 0.000 description 4
- 235000015097 nutrients Nutrition 0.000 description 4
- 239000003381 stabilizer Substances 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 206010037660 Pyrexia Diseases 0.000 description 3
- 210000001508 eye Anatomy 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 238000002649 immunization Methods 0.000 description 3
- 230000002458 infectious effect Effects 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 239000006199 nebulizer Substances 0.000 description 3
- 238000007911 parenteral administration Methods 0.000 description 3
- 230000001902 propagating effect Effects 0.000 description 3
- 230000001681 protective effect Effects 0.000 description 3
- 238000011084 recovery Methods 0.000 description 3
- 230000000241 respiratory effect Effects 0.000 description 3
- 108091003079 Bovine Serum Albumin Proteins 0.000 description 2
- 208000006339 Caliciviridae Infections Diseases 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 230000005875 antibody response Effects 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000012894 fetal calf serum Substances 0.000 description 2
- 230000027950 fever generation Effects 0.000 description 2
- 230000036039 immunity Effects 0.000 description 2
- 210000003292 kidney cell Anatomy 0.000 description 2
- 230000005923 long-lasting effect Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 239000002356 single layer Substances 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 description 2
- 239000003440 toxic substance Substances 0.000 description 2
- 230000003612 virological effect Effects 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 229930183010 Amphotericin Natural products 0.000 description 1
- QGGFZZLFKABGNL-UHFFFAOYSA-N Amphotericin A Natural products OC1C(N)C(O)C(C)OC1OC1C=CC=CC=CC=CCCC=CC=CC(C)C(O)C(C)C(C)OC(=O)CC(O)CC(O)CCC(O)C(O)CC(O)CC(O)(CC(O)C2C(O)=O)OC2C1 QGGFZZLFKABGNL-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 241000282693 Cercopithecidae Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 239000006145 Eagle's minimal essential medium Substances 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 102000004407 Lactalbumin Human genes 0.000 description 1
- 108090000942 Lactalbumin Proteins 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical group N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 241000709664 Picornaviridae Species 0.000 description 1
- 206010035148 Plague Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 229940009444 amphotericin Drugs 0.000 description 1
- APKFDSVGJQXUKY-INPOYWNPSA-N amphotericin B Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 APKFDSVGJQXUKY-INPOYWNPSA-N 0.000 description 1
- 208000022531 anorexia Diseases 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 208000010717 cat disease Diseases 0.000 description 1
- 238000004113 cell culture Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-M glutaminate Chemical compound [O-]C(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-M 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 238000007918 intramuscular administration Methods 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 201000009020 malignant peripheral nerve sheath tumor Diseases 0.000 description 1
- 210000001161 mammalian embryo Anatomy 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 208000029974 neurofibrosarcoma Diseases 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 231100000255 pathogenic effect Toxicity 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 210000003800 pharynx Anatomy 0.000 description 1
- 210000005084 renal tissue Anatomy 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 208000026425 severe pneumonia Diseases 0.000 description 1
- 206010041232 sneezing Diseases 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 229960005322 streptomycin Drugs 0.000 description 1
- 230000002381 testicular Effects 0.000 description 1
- 210000001541 thymus gland Anatomy 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/819—Viral vaccine for feline species, e.g. cats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/525,689 US3944469A (en) | 1974-11-21 | 1974-11-21 | Feline calicivirus vaccine and production thereof |
| US52568974 | 1974-11-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK516975A DK516975A (ja) | 1976-05-22 |
| DK141339B true DK141339B (da) | 1980-02-25 |
| DK141339C DK141339C (ja) | 1980-08-25 |
Family
ID=24094242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK516975AA DK141339B (da) | 1974-11-21 | 1975-11-17 | Fremgangsmåde til fremstilling af felin-calicivirus vaccine. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US3944469A (ja) |
| JP (1) | JPS5173118A (ja) |
| AT (1) | AT340584B (ja) |
| AU (1) | AU508944B2 (ja) |
| BE (1) | BE835784A (ja) |
| CA (1) | CA1055844A (ja) |
| CH (1) | CH622702A5 (ja) |
| DE (1) | DE2552137A1 (ja) |
| DK (1) | DK141339B (ja) |
| ES (1) | ES442892A1 (ja) |
| FI (1) | FI53593C (ja) |
| FR (1) | FR2291766A1 (ja) |
| GB (1) | GB1522006A (ja) |
| NL (1) | NL7513644A (ja) |
| NO (1) | NO753676L (ja) |
| SE (1) | SE7512828L (ja) |
| ZA (1) | ZA757294B (ja) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4287178A (en) * | 1974-03-25 | 1981-09-01 | Pitman-Moore, Inc. | Feline rhinotracheitis vaccine and production and use thereof |
| ZA796476B (en) * | 1978-11-30 | 1981-07-29 | Wellcome Found | Feline infectious peritonitis vaccine |
| US4303644A (en) * | 1979-10-16 | 1981-12-01 | Norden Laboratories, Inc. | Feline infectious peritonitis virus vaccines |
| US4303645A (en) * | 1980-04-18 | 1981-12-01 | Cornell Research Foundation, Inc. | Modified living canine parvovirus vaccine |
| US4537769A (en) * | 1982-04-06 | 1985-08-27 | American Cyanamid Company | Stabilization of influenza virus vaccine |
| US4522810A (en) * | 1982-12-09 | 1985-06-11 | The Regents Of The University Of California | Feline calicivirus vaccine |
| US5374424A (en) * | 1986-10-03 | 1994-12-20 | Miles Inc. | Multivalent felv-infected feline vaccine |
| ATE193725T1 (de) * | 1992-02-28 | 2000-06-15 | Chemo Sero Therapeut Res Inst | Anti-felincalicivirus rekombinanter antikörper und dafür kodierendes gen |
| WO2000076538A1 (en) | 1999-06-10 | 2000-12-21 | Michigan State University | Feline calicivirus isolated from cat urine and vaccines thereof |
| WO2004083390A2 (en) * | 2003-03-14 | 2004-09-30 | Regents Of The University Of California | Virulent systemic feline calicivirus |
| US7309495B2 (en) * | 2003-03-14 | 2007-12-18 | The Regents Of The University Of California | Hemorrhagic feline calicivirus |
| US7306807B2 (en) | 2004-09-13 | 2007-12-11 | Wyeth | Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing calicivirus infection or disease |
| CA2617341C (en) * | 2005-07-28 | 2011-03-29 | Pfizer Products Inc. | Methods of vaccine administration, new feline caliciviruses, and treatments for immunizing animals against feline paraovirus and feline herpes virus |
| MX2009013030A (es) * | 2007-05-30 | 2010-03-25 | Wyeth Llc | Poxvirus de mapache que expresa genes de antigenos felinos. |
| US10188725B2 (en) | 2015-12-14 | 2019-01-29 | Elanco Us Inc. | Hybrid core feline vaccines |
| CN114874997B (zh) * | 2022-05-26 | 2023-05-23 | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 猫杯状病毒 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1177635A (en) * | 1966-02-18 | 1970-01-14 | Wellcome Found | Cell Stains. |
-
1974
- 1974-11-21 US US05/525,689 patent/US3944469A/en not_active Expired - Lifetime
-
1975
- 1975-10-30 GB GB45026/75A patent/GB1522006A/en not_active Expired
- 1975-11-03 NO NO753676A patent/NO753676L/no unknown
- 1975-11-14 SE SE7512828A patent/SE7512828L/xx not_active Application Discontinuation
- 1975-11-17 CH CH1487975A patent/CH622702A5/de not_active IP Right Cessation
- 1975-11-17 DK DK516975AA patent/DK141339B/da unknown
- 1975-11-19 JP JP50138275A patent/JPS5173118A/ja active Pending
- 1975-11-19 AU AU86755/75A patent/AU508944B2/en not_active Expired
- 1975-11-20 FR FR7535498A patent/FR2291766A1/fr active Granted
- 1975-11-20 ZA ZA757294A patent/ZA757294B/xx unknown
- 1975-11-20 DE DE19752552137 patent/DE2552137A1/de not_active Withdrawn
- 1975-11-20 BE BE162051A patent/BE835784A/xx unknown
- 1975-11-20 CA CA240,138A patent/CA1055844A/en not_active Expired
- 1975-11-20 FI FI753274A patent/FI53593C/fi not_active IP Right Cessation
- 1975-11-20 AT AT884975A patent/AT340584B/de active
- 1975-11-21 ES ES442892A patent/ES442892A1/es not_active Expired
- 1975-11-21 NL NL7513644A patent/NL7513644A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ZA757294B (en) | 1977-06-29 |
| FI53593B (ja) | 1978-02-28 |
| BE835784A (fr) | 1976-05-20 |
| CH622702A5 (ja) | 1981-04-30 |
| US3944469A (en) | 1976-03-16 |
| FI753274A (ja) | 1976-05-22 |
| AT340584B (de) | 1977-12-27 |
| FR2291766B1 (ja) | 1978-07-28 |
| NL7513644A (nl) | 1976-05-25 |
| NO753676L (ja) | 1976-05-24 |
| SE7512828L (sv) | 1976-05-24 |
| AU8675575A (en) | 1977-05-26 |
| ATA884975A (de) | 1977-04-15 |
| DE2552137A1 (de) | 1976-05-26 |
| FI53593C (fi) | 1978-06-12 |
| CA1055844A (en) | 1979-06-05 |
| ES442892A1 (es) | 1977-08-16 |
| AU508944B2 (en) | 1980-04-17 |
| DK141339C (ja) | 1980-08-25 |
| FR2291766A1 (fr) | 1976-06-18 |
| GB1522006A (en) | 1978-08-23 |
| JPS5173118A (ja) | 1976-06-24 |
| DK516975A (ja) | 1976-05-22 |
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