DK1408981T3 - Fremgangsmåder til forebyggelse af vægtforögelse som fölge af antipsykotiske midler - Google Patents

Fremgangsmåder til forebyggelse af vægtforögelse som fölge af antipsykotiske midler

Info

Publication number
DK1408981T3
DK1408981T3 DK02750269T DK02750269T DK1408981T3 DK 1408981 T3 DK1408981 T3 DK 1408981T3 DK 02750269 T DK02750269 T DK 02750269T DK 02750269 T DK02750269 T DK 02750269T DK 1408981 T3 DK1408981 T3 DK 1408981T3
Authority
DK
Denmark
Prior art keywords
methods
weight gain
result
receptor antagonist
glucocorticoid receptor
Prior art date
Application number
DK02750269T
Other languages
Danish (da)
English (en)
Inventor
Joseph K Belanoff
Alan F Schatzberg
Original Assignee
Corcept Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corcept Therapeutics Inc filed Critical Corcept Therapeutics Inc
Application granted granted Critical
Publication of DK1408981T3 publication Critical patent/DK1408981T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
DK02750269T 2001-07-23 2002-07-22 Fremgangsmåder til forebyggelse af vægtforögelse som fölge af antipsykotiske midler DK1408981T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30769301P 2001-07-23 2001-07-23
PCT/US2002/023441 WO2003009853A1 (en) 2001-07-23 2002-07-22 Methods for preventing antipsychotic-induced weight gain

Publications (1)

Publication Number Publication Date
DK1408981T3 true DK1408981T3 (da) 2009-01-12

Family

ID=23190816

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02750269T DK1408981T3 (da) 2001-07-23 2002-07-22 Fremgangsmåder til forebyggelse af vægtforögelse som fölge af antipsykotiske midler

Country Status (20)

Country Link
US (1) US6680310B2 (pt)
EP (1) EP1408981B1 (pt)
JP (2) JP2004537563A (pt)
KR (1) KR20040028942A (pt)
CN (2) CN1547473A (pt)
AT (1) ATE406166T1 (pt)
AU (1) AU2002319665B2 (pt)
BR (1) BR0211365A (pt)
CA (1) CA2454339C (pt)
CY (1) CY1108562T1 (pt)
DE (1) DE60228579D1 (pt)
DK (1) DK1408981T3 (pt)
ES (1) ES2312598T3 (pt)
HK (1) HK1061526A1 (pt)
IL (1) IL159913A0 (pt)
MX (1) MXPA04000692A (pt)
NZ (1) NZ530724A (pt)
PT (1) PT1408981E (pt)
WO (1) WO2003009853A1 (pt)
ZA (1) ZA200400444B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1868480A (zh) * 2001-08-31 2006-11-29 科塞普特治疗公司 抑制成年唐氏综合症患者认知退化的方法
NZ527142A (en) * 2003-07-23 2006-03-31 Douglas Pharmaceuticals Ltd A stable suspension formulation
GB0400031D0 (en) 2004-01-03 2004-02-04 Univ Sheffield Depression treatment
US20050171088A1 (en) * 2004-01-30 2005-08-04 Astrazeneca Ab Treatment of psychoses with dibenzothiazepine antipsychotic
US20060211667A1 (en) * 2005-03-21 2006-09-21 Eric Marchewitz Use of pregnane steroid derivatives for enhancing physical performance
WO2007067714A2 (en) * 2005-12-08 2007-06-14 The Mclean Hospital Corporation Treatment of sequelae of psychiatric disorders
WO2008128166A1 (en) * 2007-04-13 2008-10-23 Concert Pharmaceuticals Inc. Deuterated derivatives of 4-(6-fluoro-1, 2-benzisoxazol-3-yl) piperidine compounds
US10500216B2 (en) 2011-11-18 2019-12-10 Corcept Therapeutics, Inc. Optimizing mifepristone absorption
US8859774B2 (en) 2012-05-25 2014-10-14 Corcept Therapeutics, Inc. Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
CN109761976B (zh) 2013-11-25 2021-11-23 科赛普特治疗公司 八氢稠合的氮杂萘烷糖皮质激素受体调节剂
US9943526B2 (en) 2015-04-21 2018-04-17 Corcept Therapeutics, Inc. Optimizing mifepristone levels for cushing's patients
EP3600282A4 (en) 2017-03-31 2020-08-19 Corcept Therapeutics, Inc. GLUCOCORTICOID RECEPTOR MODULATORS FOR THE TREATMENT OF COLD CANCER
US11273166B2 (en) 2017-06-13 2022-03-15 Monash University Methods and compositions for the treatment of obesity
SG11202105770YA (en) 2018-12-19 2021-07-29 Corcept Therapeutics Inc Pharmaceutical formulations containing relacorilant, a heteroaryl-ketone fused azadecalin compound
WO2020132046A1 (en) 2018-12-19 2020-06-25 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
US11234971B2 (en) 2018-12-19 2022-02-01 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
US11058670B2 (en) 2019-02-22 2021-07-13 Corcept Therapeutics Incorporated Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator
AU2020239920A1 (en) * 2019-03-18 2021-11-04 Arnold L. Newman Method of improving insulin sensitivity
JP2023505948A (ja) 2019-12-11 2023-02-14 コーセプト セラピューティクス, インコーポレイテッド 抗精神病薬誘発性体重増加のミリコリラントによる治療方法
BR112022022473A2 (pt) 2020-05-06 2022-12-13 Corcept Therapeutics Inc Formulações de moduladores de receptor de glucocorticoide ciclo-hexil pirimidina

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757400B1 (fr) * 1996-12-19 1999-12-17 Hoechst Marion Roussel Inc Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs
AU5729098A (en) 1996-12-24 1998-07-17 Zymogenetics Inc. Treatment agents and methods for treating type ii diabetes and symptoms of type ii diabetes
ATE332696T1 (de) * 1997-10-06 2006-08-15 Univ Leland Stanford Junior Methode zur behandlung von durch glycocorticoidstörungen verursachten psychosen
AU756818B2 (en) 1998-05-15 2003-01-23 Board Of Trustees Of The Leland Stanford Junior University Glucocorticoid receptor antagonists for the treatment of dementia
EP1223939A1 (en) * 1999-05-19 2002-07-24 AstraZeneca AB Method of treating weight gain

Also Published As

Publication number Publication date
AU2002319665B2 (en) 2006-09-21
CA2454339C (en) 2012-01-10
PT1408981E (pt) 2008-12-04
MXPA04000692A (es) 2004-04-21
JP2009102413A (ja) 2009-05-14
CN1547473A (zh) 2004-11-17
NZ530724A (en) 2005-09-30
EP1408981A4 (en) 2005-06-08
KR20040028942A (ko) 2004-04-03
EP1408981A1 (en) 2004-04-21
IL159913A0 (en) 2004-06-20
EP1408981B1 (en) 2008-08-27
JP2004537563A (ja) 2004-12-16
US6680310B2 (en) 2004-01-20
ZA200400444B (en) 2005-03-30
BR0211365A (pt) 2004-09-21
HK1061526A1 (en) 2004-09-24
CA2454339A1 (en) 2003-02-06
DE60228579D1 (de) 2008-10-09
CY1108562T1 (el) 2014-04-09
WO2003009853A1 (en) 2003-02-06
US20030027802A1 (en) 2003-02-06
ES2312598T3 (es) 2009-03-01
ATE406166T1 (de) 2008-09-15
CN1853722A (zh) 2006-11-01

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