DK1408981T3 - Fremgangsmåder til forebyggelse af vægtforögelse som fölge af antipsykotiske midler - Google Patents

Fremgangsmåder til forebyggelse af vægtforögelse som fölge af antipsykotiske midler

Info

Publication number
DK1408981T3
DK1408981T3 DK02750269T DK02750269T DK1408981T3 DK 1408981 T3 DK1408981 T3 DK 1408981T3 DK 02750269 T DK02750269 T DK 02750269T DK 02750269 T DK02750269 T DK 02750269T DK 1408981 T3 DK1408981 T3 DK 1408981T3
Authority
DK
Denmark
Prior art keywords
methods
weight gain
result
receptor antagonist
glucocorticoid receptor
Prior art date
Application number
DK02750269T
Other languages
English (en)
Inventor
Joseph K Belanoff
Alan F Schatzberg
Original Assignee
Corcept Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corcept Therapeutics Inc filed Critical Corcept Therapeutics Inc
Application granted granted Critical
Publication of DK1408981T3 publication Critical patent/DK1408981T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK02750269T 2001-07-23 2002-07-22 Fremgangsmåder til forebyggelse af vægtforögelse som fölge af antipsykotiske midler DK1408981T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30769301P 2001-07-23 2001-07-23
PCT/US2002/023441 WO2003009853A1 (en) 2001-07-23 2002-07-22 Methods for preventing antipsychotic-induced weight gain

Publications (1)

Publication Number Publication Date
DK1408981T3 true DK1408981T3 (da) 2009-01-12

Family

ID=23190816

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02750269T DK1408981T3 (da) 2001-07-23 2002-07-22 Fremgangsmåder til forebyggelse af vægtforögelse som fölge af antipsykotiske midler

Country Status (20)

Country Link
US (1) US6680310B2 (da)
EP (1) EP1408981B1 (da)
JP (2) JP2004537563A (da)
KR (1) KR20040028942A (da)
CN (2) CN1853722A (da)
AT (1) ATE406166T1 (da)
AU (1) AU2002319665B2 (da)
BR (1) BR0211365A (da)
CA (1) CA2454339C (da)
CY (1) CY1108562T1 (da)
DE (1) DE60228579D1 (da)
DK (1) DK1408981T3 (da)
ES (1) ES2312598T3 (da)
HK (1) HK1061526A1 (da)
IL (1) IL159913A0 (da)
MX (1) MXPA04000692A (da)
NZ (1) NZ530724A (da)
PT (1) PT1408981E (da)
WO (1) WO2003009853A1 (da)
ZA (1) ZA200400444B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1556708A (zh) * 2001-08-31 2004-12-22 �Ƹ��� 抑制成年唐氏综合症患者认知退化的方法
NZ527142A (en) * 2003-07-23 2006-03-31 Douglas Pharmaceuticals Ltd A stable suspension formulation
GB0400031D0 (en) 2004-01-03 2004-02-04 Univ Sheffield Depression treatment
US20050171088A1 (en) * 2004-01-30 2005-08-04 Astrazeneca Ab Treatment of psychoses with dibenzothiazepine antipsychotic
US20060211667A1 (en) * 2005-03-21 2006-09-21 Eric Marchewitz Use of pregnane steroid derivatives for enhancing physical performance
WO2007067714A2 (en) * 2005-12-08 2007-06-14 The Mclean Hospital Corporation Treatment of sequelae of psychiatric disorders
WO2008128166A1 (en) * 2007-04-13 2008-10-23 Concert Pharmaceuticals Inc. Deuterated derivatives of 4-(6-fluoro-1, 2-benzisoxazol-3-yl) piperidine compounds
US10500216B2 (en) 2011-11-18 2019-12-10 Corcept Therapeutics, Inc. Optimizing mifepristone absorption
US8859774B2 (en) 2012-05-25 2014-10-14 Corcept Therapeutics, Inc. Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
PT3074011T (pt) * 2013-11-25 2019-09-17 Corcept Therapeutics Inc Moduladores de receptores de glicocorticoides de azadecalina fundidas com octa-hidro
US9943526B2 (en) 2015-04-21 2018-04-17 Corcept Therapeutics, Inc. Optimizing mifepristone levels for cushing's patients
UA127409C2 (uk) 2017-03-31 2023-08-16 Корцепт Терап'Ютікс, Інк. Модулятори глюкокортикоїдного рецептора для лікування раку шийки матки
US11273166B2 (en) 2017-06-13 2022-03-15 Monash University Methods and compositions for the treatment of obesity
US11234971B2 (en) 2018-12-19 2022-02-01 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
US11389432B2 (en) 2018-12-19 2022-07-19 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
CN113194931B (zh) 2018-12-19 2023-11-10 科塞普特治疗公司 含有瑞拉可兰、杂芳基-酮稠合的氮杂十氢化萘化合物的药物制剂
CA3131263C (en) 2019-02-22 2024-01-02 Corcept Therapeutics Incorporated Therapeutic uses of relacorilant, a heteroaryl-ketone fused azadecalin glucocorticoid receptor modulator
WO2020190351A1 (en) * 2019-03-18 2020-09-24 Nieman Lynnette K Method for improving insulin sensitivity
CN114929229A (zh) * 2019-12-11 2022-08-19 科赛普特治疗学股份有限公司 用米立可兰治疗抗精神病药导致的体重增加的方法
US20210361651A1 (en) 2020-05-06 2021-11-25 Corcept Therapeutics Incorporated Formulations of pyrimidine cyclohexyl glucocorticoid receptor modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757400B1 (fr) * 1996-12-19 1999-12-17 Hoechst Marion Roussel Inc Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs
WO1998027986A1 (en) * 1996-12-24 1998-07-02 Zymogenetics, Inc. Treatment agents and methods for treating type ii diabetes and symptoms of type ii diabetes
AU747956B2 (en) * 1997-10-06 2002-05-30 Board Of Trustees Of The Leland Stanford Junior University Methods for treating psychosis associated with glucocorticoid related dysfunction
AU756818B2 (en) 1998-05-15 2003-01-23 Board Of Trustees Of The Leland Stanford Junior University Glucocorticoid receptor antagonists for the treatment of dementia
WO2000071106A2 (en) * 1999-05-19 2000-11-30 Astrazeneca Ab Method of treating weight gain

Also Published As

Publication number Publication date
EP1408981B1 (en) 2008-08-27
WO2003009853A1 (en) 2003-02-06
NZ530724A (en) 2005-09-30
DE60228579D1 (de) 2008-10-09
CA2454339C (en) 2012-01-10
EP1408981A1 (en) 2004-04-21
PT1408981E (pt) 2008-12-04
JP2009102413A (ja) 2009-05-14
CN1547473A (zh) 2004-11-17
US20030027802A1 (en) 2003-02-06
EP1408981A4 (en) 2005-06-08
BR0211365A (pt) 2004-09-21
CN1853722A (zh) 2006-11-01
CA2454339A1 (en) 2003-02-06
AU2002319665B2 (en) 2006-09-21
KR20040028942A (ko) 2004-04-03
JP2004537563A (ja) 2004-12-16
MXPA04000692A (es) 2004-04-21
US6680310B2 (en) 2004-01-20
CY1108562T1 (el) 2014-04-09
ZA200400444B (en) 2005-03-30
ATE406166T1 (de) 2008-09-15
IL159913A0 (en) 2004-06-20
HK1061526A1 (en) 2004-09-24
ES2312598T3 (es) 2009-03-01

Similar Documents

Publication Publication Date Title
CY1108562T1 (el) Μεθοδοι για την προληψη προσληψης βαρους η οποια προκαλειται απο αντιψυχωτικες θεραπειες
IL139672A (en) Glucocorticoid receptor antagonists for the tretment of dementia
DK1023074T3 (da) Fremgangsmåder til behandling af psykose forbundet med glucocorticoid-relateret dysfunktion
WO2002076390A3 (en) Methods for treating stress disorders using glucocorticoid receptor-specific antagonists
NO20070723L (no) Progesteron reseptormodulatorer inneholdende pyrrol-oksindolderivater og deres anvendelse
NO20070742L (no) Progesteron reseptormodulatorer inneholdende pyrrol-oksindolderivater og deres anvendelse.
AU2003228283A1 (en) Quinazolinone modulators of nuclear receptors
WO2004058717A8 (en) Isoquinolinone derivatives and their use as therapeutic agents
ZA200700616B (en) Modified pyrimidine glucocorticoid receptor modulatore
ECSP066468A (es) Antagonistas de receptores muscarínicos de acetilcolina
CL2004000449A1 (es) Compuestos derivados de imidazol-4-il-etinil-piridina, para tratar trastornos mediados por el receptor mglur5; procedimiento de preparacion de los compuestos; composicion farmaceutica que comprende a uno de los compuestos; y uso de los compuestos en
DK1467762T3 (da) Anvendelse af en H1-antagonist og rimexolon som et sikkert steroid til behandling af rhinitis
IL160649A0 (en) Methods for inhibiting cognitive deterioration in adults with down syndrome
WO2004069202A3 (en) Antiglucocorticoids for the treatment of postpartum psychosis
IL158744A0 (en) Methods for treating delirium using glucocorticoid receptor-specific antagonists
DK1420789T3 (da) Anvendelse af aktivstoffer med my-opioid-receptoragonistisk virkning og opioid-receptorantagonistisk virkning som kombinationslægemidler til cancerbehandling
WO2002020526A3 (en) Cyclic and acyclic amidines and pharmaceutical compositions containing them for use as progesterone receptor binding agents