BR0211365A - Método e kit para inibir ou reverter o ganho de peso em um paciente sendo tratado com uma medicação antipsicótica - Google Patents

Método e kit para inibir ou reverter o ganho de peso em um paciente sendo tratado com uma medicação antipsicótica

Info

Publication number
BR0211365A
BR0211365A BR0211365-1A BR0211365A BR0211365A BR 0211365 A BR0211365 A BR 0211365A BR 0211365 A BR0211365 A BR 0211365A BR 0211365 A BR0211365 A BR 0211365A
Authority
BR
Brazil
Prior art keywords
weight gain
inhibiting
kit
patient receiving
receptor antagonist
Prior art date
Application number
BR0211365-1A
Other languages
English (en)
Inventor
Joseph K Belanoff
Alan F Schatzberg
Original Assignee
Corcept Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corcept Therapeutics Inc filed Critical Corcept Therapeutics Inc
Publication of BR0211365A publication Critical patent/BR0211365A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

"MéTODO E KIT PARA INIBIR OU REVERTER O GANHO DE PESO EM UM PACIENTE SENDO TRATADO COM UMA MEDICAçãO ANTIPSICóTICA". Esta invenção pertence, genericamente, ao campo da psiquiatria. Em particular, esta invenção pertence à verificação de que, agentes capazes de inibir a ligação do cortisol a seus receptores, podem ser usados em métodos para impedir ganho de peso induzido por antipsicótico. A mifepristona, um potente antagonista de receptor de glicocorticóide específico, pode ser usada nestes métodos. A invenção também provê um kit para prevenir o ganho de peso induzido por AP em um humano, incluindo um antagonista de receptor de glicocorticóide e material instrucional dando as indicações, dosagem e programa de administração do antagonista de receptor de glicocorticóide.
BR0211365-1A 2001-07-23 2002-07-22 Método e kit para inibir ou reverter o ganho de peso em um paciente sendo tratado com uma medicação antipsicótica BR0211365A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30769301P 2001-07-23 2001-07-23
PCT/US2002/023441 WO2003009853A1 (en) 2001-07-23 2002-07-22 Methods for preventing antipsychotic-induced weight gain

Publications (1)

Publication Number Publication Date
BR0211365A true BR0211365A (pt) 2004-09-21

Family

ID=23190816

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0211365-1A BR0211365A (pt) 2001-07-23 2002-07-22 Método e kit para inibir ou reverter o ganho de peso em um paciente sendo tratado com uma medicação antipsicótica

Country Status (20)

Country Link
US (1) US6680310B2 (pt)
EP (1) EP1408981B1 (pt)
JP (2) JP2004537563A (pt)
KR (1) KR20040028942A (pt)
CN (2) CN1853722A (pt)
AT (1) ATE406166T1 (pt)
AU (1) AU2002319665B2 (pt)
BR (1) BR0211365A (pt)
CA (1) CA2454339C (pt)
CY (1) CY1108562T1 (pt)
DE (1) DE60228579D1 (pt)
DK (1) DK1408981T3 (pt)
ES (1) ES2312598T3 (pt)
HK (1) HK1061526A1 (pt)
IL (1) IL159913A0 (pt)
MX (1) MXPA04000692A (pt)
NZ (1) NZ530724A (pt)
PT (1) PT1408981E (pt)
WO (1) WO2003009853A1 (pt)
ZA (1) ZA200400444B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040029116A (ko) * 2001-08-31 2004-04-03 코어셉트 쎄라퓨틱스, 잉크. 다운 증후군에 걸린 성인에서의 인지 장애 억제 방법
NZ527142A (en) * 2003-07-23 2006-03-31 Douglas Pharmaceuticals Ltd A stable suspension formulation
GB0400031D0 (en) 2004-01-03 2004-02-04 Univ Sheffield Depression treatment
US20050171088A1 (en) * 2004-01-30 2005-08-04 Astrazeneca Ab Treatment of psychoses with dibenzothiazepine antipsychotic
US20060211667A1 (en) * 2005-03-21 2006-09-21 Eric Marchewitz Use of pregnane steroid derivatives for enhancing physical performance
US8551986B2 (en) * 2005-12-08 2013-10-08 The Mclean Hospital Corporation Treatment of sequelae of psychiatric disorders
US8198305B2 (en) * 2007-04-13 2012-06-12 Concert Pharmaceuticals Inc. 1,2-benzisoxazol-3-yl compounds
US10500216B2 (en) 2011-11-18 2019-12-10 Corcept Therapeutics, Inc. Optimizing mifepristone absorption
US8859774B2 (en) 2012-05-25 2014-10-14 Corcept Therapeutics, Inc. Heteroaryl-ketone fused azadecalin glucocorticoid receptor modulators
EP3848027B1 (en) 2013-11-25 2023-04-05 Corcept Therapeutics Incorporated Octahydro fused azadecalin glucocorticoid receptor modulators
US9943526B2 (en) 2015-04-21 2018-04-17 Corcept Therapeutics, Inc. Optimizing mifepristone levels for cushing's patients
WO2018183947A1 (en) 2017-03-31 2018-10-04 Corcept Therapeutics, Inc. Glucocorticoid receptor modulators to treat cervical cancer
WO2018227248A1 (en) * 2017-06-13 2018-12-20 Monash University Methods and compositions for the treatment of obesity
US11389432B2 (en) 2018-12-19 2022-07-19 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
CN117281790A (zh) 2018-12-19 2023-12-26 科塞普特治疗公司 含有瑞拉可兰、杂芳基-酮稠合的氮杂十氢化萘化合物的药物制剂
US11234971B2 (en) 2018-12-19 2022-02-01 Corcept Therapeutics Incorporated Methods of treating cancer comprising administration of a glucocorticoid receptor modulator and a cancer chemotherapy agent
JP2022523376A (ja) 2019-02-22 2022-04-22 コーセプト セラピューティクス， インコーポレイテッド レラコリラント、ヘテロアリール－ケトン縮合アザデカリングルココルチコイド受容体調節物質の治療用途
KR20210153056A (ko) * 2019-03-18 2021-12-16 리네트 케이. 니만 인슐린 감수성 개선 방법
KR20220113767A (ko) 2019-12-11 2022-08-16 코어셉트 쎄라퓨틱스 인코포레이티드 미리코릴란트로 항정신병약-유도 체중 증가를 치료하는 방법
EP4146173A4 (en) 2020-05-06 2024-05-29 Corcept Therapeutics Inc FORMULATIONS OF PYRIMIDINE-CYCLOHEXYL-GLUCOCORTICOID RECEPTOR MODULATORS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2757400B1 (fr) * 1996-12-19 1999-12-17 Hoechst Marion Roussel Inc Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs
US5929058A (en) 1996-12-24 1999-07-27 Zymogenetics, Inc. Treatment agents and methods for treating type II diabetes and symptoms of type II diabetes
EP1023074B1 (en) * 1997-10-06 2006-07-12 The Board Of Trustees Of The Leland Stanford Junior University Methods for treating psychosis associated with glucocorticoid related dysfunction
WO1999059596A1 (en) 1998-05-15 1999-11-25 The Board Of Trustees Of Leland Stanford Junior University Glucocorticoid receptor antagonists for the treatment of dementia
JP2003500353A (ja) * 1999-05-19 2003-01-07 アストラゼネカ・アクチエボラーグ 処置方法

Also Published As

Publication number Publication date
EP1408981A1 (en) 2004-04-21
EP1408981B1 (en) 2008-08-27
ZA200400444B (en) 2005-03-30
DK1408981T3 (da) 2009-01-12
IL159913A0 (en) 2004-06-20
JP2004537563A (ja) 2004-12-16
AU2002319665B2 (en) 2006-09-21
EP1408981A4 (en) 2005-06-08
US20030027802A1 (en) 2003-02-06
WO2003009853A1 (en) 2003-02-06
DE60228579D1 (de) 2008-10-09
JP2009102413A (ja) 2009-05-14
CN1853722A (zh) 2006-11-01
US6680310B2 (en) 2004-01-20
ATE406166T1 (de) 2008-09-15
KR20040028942A (ko) 2004-04-03
CN1547473A (zh) 2004-11-17
PT1408981E (pt) 2008-12-04
NZ530724A (en) 2005-09-30
CY1108562T1 (el) 2014-04-09
CA2454339A1 (en) 2003-02-06
MXPA04000692A (es) 2004-04-21
HK1061526A1 (en) 2004-09-24
CA2454339C (en) 2012-01-10
ES2312598T3 (es) 2009-03-01

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA INT.CL: A61K 31/56, A61P 25/00

Ipc: A61K 31/56 (2011.01)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]