DK140834C - - Google Patents

Info

Publication number
DK140834C
DK140834C DK457475A DK457475A DK140834C DK 140834 C DK140834 C DK 140834C DK 457475 A DK457475 A DK 457475A DK 457475 A DK457475 A DK 457475A DK 140834 C DK140834 C DK 140834C
Authority
DK
Denmark
Application number
DK457475A
Other languages
Danish (da)
Other versions
DK140834B (da
DK457475A (ko
Inventor
U Fischer
E Lorch
Original Assignee
Hoffmann F. La Roche & Co Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann F. La Roche & Co Ag filed Critical Hoffmann F. La Roche & Co Ag
Publication of DK457475A publication Critical patent/DK457475A/da
Publication of DK140834B publication Critical patent/DK140834B/da
Application granted granted Critical
Publication of DK140834C publication Critical patent/DK140834C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK457475AA 1974-10-11 1975-10-10 Analogifremgangsmåde til fremstilling af biguanidsalte. DK140834B (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1369774A CH602612A5 (ko) 1974-10-11 1974-10-11

Publications (3)

Publication Number Publication Date
DK457475A DK457475A (ko) 1976-04-12
DK140834B DK140834B (da) 1979-11-26
DK140834C true DK140834C (ko) 1980-04-28

Family

ID=4394567

Family Applications (1)

Application Number Title Priority Date Filing Date
DK457475AA DK140834B (da) 1974-10-11 1975-10-10 Analogifremgangsmåde til fremstilling af biguanidsalte.

Country Status (26)

Country Link
US (1) US4028402A (ko)
JP (1) JPS51125718A (ko)
AR (1) AR209457A1 (ko)
AT (1) AT343676B (ko)
BE (1) BE834369A (ko)
BR (1) BR7506595A (ko)
CA (1) CA1053258A (ko)
CH (1) CH602612A5 (ko)
CU (1) CU34371A (ko)
DD (1) DD123322A5 (ko)
DE (1) DE2542598A1 (ko)
DK (1) DK140834B (ko)
ES (1) ES441673A1 (ko)
FI (1) FI752626A (ko)
FR (1) FR2287221A1 (ko)
GB (1) GB1473256A (ko)
IE (1) IE41807B1 (ko)
IL (1) IL48116A (ko)
LU (1) LU73557A1 (ko)
NL (1) NL7511890A (ko)
NO (1) NO753447L (ko)
PH (1) PH12279A (ko)
PL (1) PL95259B1 (ko)
SE (1) SE7511357L (ko)
SU (1) SU572200A3 (ko)
ZA (1) ZA755861B (ko)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2401898A1 (fr) * 1977-09-05 1979-03-30 Aec Chim Organ Biolog Nouveau sel de l'acide patoique
US20020006899A1 (en) * 1998-10-06 2002-01-17 Pospisilik Andrew J. Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals
DE122010000020I1 (de) 1996-04-25 2010-07-08 Prosidion Ltd Verfahren zur Senkung des Blutglukosespiegels in Säugern
EP1004304A4 (en) 1996-12-24 2002-10-16 Sumitomo Pharma COMPOSITION WITH ACORBIC ACID
DE19823831A1 (de) * 1998-05-28 1999-12-02 Probiodrug Ges Fuer Arzneim Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
DE19828113A1 (de) 1998-06-24 2000-01-05 Probiodrug Ges Fuer Arzneim Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
DE19828114A1 (de) 1998-06-24 2000-01-27 Probiodrug Ges Fuer Arzneim Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
DE19834591A1 (de) 1998-07-31 2000-02-03 Probiodrug Ges Fuer Arzneim Verfahren zur Steigerung des Blutglukosespiegels in Säugern
US20030176357A1 (en) * 1998-10-06 2003-09-18 Pospisilik Andrew J. Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels
DE19926233C1 (de) 1999-06-10 2000-10-19 Probiodrug Ges Fuer Arzneim Verfahren zur Herstellung von Thiazolidin
DE19940130A1 (de) * 1999-08-24 2001-03-01 Probiodrug Ges Fuer Arzneim Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
EP1228756A4 (en) 1999-10-06 2004-06-09 Kurokawa Kiyoshi AGENTS FOR RELIEVING CARBONYL-INDUCED STRESS
US20080076811A1 (en) * 2000-01-21 2008-03-27 Bork Balkan Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents
EP2266665B1 (en) 2000-03-31 2016-05-11 Royalty Pharma Collection Trust Method for the improvement of islet signaling in diabetes mellitus and for its prevention
FR2809310B1 (fr) 2000-05-26 2004-02-13 Centre Nat Rech Scient Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
JP2005097117A (ja) * 2000-06-30 2005-04-14 Chugai Pharmaceut Co Ltd 糖尿病治療剤
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
EP1328270A2 (en) * 2000-10-27 2003-07-23 Probiodrug AG Method for the treatment of neurological and neuropsychological disorders
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
US20030130199A1 (en) 2001-06-27 2003-07-10 Von Hoersten Stephan Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
DE10150203A1 (de) 2001-10-12 2003-04-17 Probiodrug Ag Peptidylketone als Inhibitoren der DPIV
WO2003015768A2 (en) * 2001-08-16 2003-02-27 Probiodrug Ag Use of inhibitors of proline endopeptidase to modulate inositol (1,4,5) triphosphate concentration dependent on intracellular signal cascades
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
UA76309C2 (en) 2002-02-28 2006-07-17 Prosidion Ltd Dpiv inhibitors based on glutaminyl
US20030232761A1 (en) * 2002-03-28 2003-12-18 Hinke Simon A. Novel analogues of glucose-dependent insulinotropic polypeptide
US20040033051A1 (en) * 2002-08-16 2004-02-19 Ip Kiril Kun Wan Method and system for producing and displaying visual presentations which inhibit off-screen duplication
US20040058876A1 (en) * 2002-09-18 2004-03-25 Torsten Hoffmann Secondary binding site of dipeptidyl peptidase IV (DP IV)
EP1543023B1 (en) * 2002-09-18 2010-03-17 Prosidion Limited Secondary binding site of dipeptidyl peptidase iv (dp iv)
EP1620091B1 (en) 2003-05-05 2010-03-31 Probiodrug AG Inhibitors of glutaminyl cyclase
PT1620082E (pt) 2003-05-05 2010-06-11 Probiodrug Ag Utilização médica de inibidores de ciclases de glutaminilo e glutamato para o tratamento da doença de alzheimer e síndrome de down
JP5707014B2 (ja) * 2003-10-15 2015-04-22 プロビオドルグ エージー グルタミニル、及びグルタミン酸シクラーゼのエフェクターの使用
US20050171112A1 (en) * 2003-11-03 2005-08-04 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
US20100099721A1 (en) * 2003-11-03 2010-04-22 Probiodrug Ag Novel compounds for the treatment of neurological disorders
KR101099206B1 (ko) 2004-02-05 2011-12-27 프로비오드룩 아게 신규한 글루타미닐 시클라제 저해제
CN105152983A (zh) 2007-01-29 2015-12-16 韩诺生物制药株式会社 N,n-二甲基亚氨基二碳亚氨酸二酰胺乙酸盐、其制备方法和包含其的药物组合物
WO2008097861A2 (en) * 2007-02-02 2008-08-14 Braincells, Inc. MODULATION OF NEUROGENESIS WITH BIGUANIDES AND GSK3-ß AGENTS
KR101226669B1 (ko) * 2007-09-21 2013-01-25 한올바이오파마주식회사 Ｎ,ｎ－디메틸 이미도디카르본이미딕 디아미드의 디카르복실산염, 그의 제조 방법 및 그의 약제학적 조성물
WO2009088220A2 (ko) * 2008-01-08 2009-07-16 Hanall Pharmaceutical Company. Ltd Ｎ,ｎ-디메틸 이미도디카르본이미딕 디아미드의 니코틴산염, 그의 제조방법 및 그를 포함하는 약제학적 조성물
WO2009144527A1 (en) 2008-06-26 2009-12-03 Laboratorios Silanes, S.A. De C.V. A new metformin glycinate salt for blood glucose control
WO2010146604A2 (en) 2009-06-18 2010-12-23 Exemed Pharmaceuticals Processes for preparing metformin hydrochloride
WO2011049400A2 (ko) * 2009-10-23 2011-04-28 한올바이오파마주식회사 N,n-디메틸 이미도디카르본이미딕 디아미드의 산 부가염을 포함하는 항암용 약제학적 조성물
KR101324283B1 (ko) 2010-04-27 2013-11-01 한올바이오파마주식회사 바이구아나이드 화합물의 신규 염, 그의 제조방법, 그를 포함하는 약제학적 조성물
MX2019003725A (es) 2016-09-30 2019-08-12 Laboratorios Silanes S A De C V Glicinato de metformina, composiciones farmaceuticas que comprenden la misma, y metodos de uso de la misma.
US11510886B2 (en) 2016-09-30 2022-11-29 Laboratorios Silanes, S.A. De C.V. Metformin amino acid compounds and methods of using the same
CN107118130A (zh) * 2017-05-11 2017-09-01 杜剑平 一类治疗肿瘤的药物化合物及其应用
CN106986791A (zh) * 2017-05-11 2017-07-28 杜剑平 一种治疗肿瘤的药物化合物及其制备方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3179562A (en) * 1961-08-23 1965-04-20 Du Pont Treatment of diabetes with alpha, alpha substituted acetic acid derivatives

Also Published As

Publication number Publication date
IE41807L (en) 1976-04-11
DD123322A5 (ko) 1976-12-12
ATA776375A (de) 1977-10-15
PH12279A (en) 1978-12-12
BR7506595A (pt) 1976-08-17
DK140834B (da) 1979-11-26
CU34371A (es) 1979-06-01
US4028402A (en) 1977-06-07
PL95259B1 (pl) 1977-10-31
BE834369A (fr) 1976-04-12
AT343676B (de) 1978-06-12
FR2287221A1 (fr) 1976-05-07
IL48116A0 (en) 1975-11-25
JPS51125718A (en) 1976-11-02
SE7511357L (sv) 1976-04-12
FI752626A (ko) 1976-04-12
SU572200A3 (ru) 1977-09-05
AR209457A1 (es) 1977-04-29
DE2542598A1 (de) 1976-04-22
AU8497775A (en) 1977-03-24
ES441673A1 (es) 1977-04-01
IE41807B1 (en) 1980-03-26
IL48116A (en) 1979-07-25
NO753447L (ko) 1976-04-13
LU73557A1 (ko) 1977-05-24
GB1473256A (en) 1977-05-11
NL7511890A (nl) 1976-04-13
CA1053258A (en) 1979-04-24
DK457475A (ko) 1976-04-12
ZA755861B (en) 1976-08-25
CH602612A5 (ko) 1978-07-31

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